SGLT2 (sodium-glucose-co-transporter 2) inhibitor is an oral tablet used in conjunction with exercise and diet to improve blood glucose control in Type 2 diabetes mellitus patients.

The medication works by targeting and helping prevent sodium-glucose transport proteins from allowing glucose that has been filtered by the kidneys to be reabsorbed into your bloodstream.

Who is SGLT2 Inhibitor suitable for?

This drug is not suitable for everyone. Selection of the right patients is crucial to understand the mechanism of the medication and see improvement in the condition.

SGLT2 Inhibitor is given to patients with Type 2 diabetes mellitus as a second-line drug in case the first line of treatment, metformin, fails to keep high blood sugar levels in check.

If the patient has hyperglycemia i.e. high, uncontrolled blood sugar, and a Body Mass Index (BMI) equal to or greater than 30 due to the accumulation of fat in the abdominal region (central obesity), then SGLT2 Inhibitor could be a useful medication. The drug not only works to reduce high blood glucose but also helps with weight loss. However, in patients with normal BMI, the medication does not induce weight loss.

SGLT2 Inhibitor may not be suitable for patients with a history of urinary tract infection. Hence, it is advisable for all patients to undergo a urine test before starting with the dosage. If the test results are normal, then only you can discuss the dosage with your doctor/healthcare provider and start taking the prescribed medications immediately.

Benefits of Taking SGLT2 Inhibitor :

The benefits of using SGLT2 Inhibitor are as follows  

Helps reduce excess weight if the patient is obese. If taken in the correct dosage as prescribed, you can lose up to 5 Kgs in about three months.

Helps reduce Systolic blood pressure   if a diabetic is living with hypertension, SGLT2 Inhibitor can bring down systolic blood pressure.

As an anti-diabetic drug, SGLT2 Inhibitor works to control high blood glucose and improves glycemic control. Thus, with the help of the drug, Type 2 diabetes mellitus patients can keep their HbA1c levels at 7% or less.

Side Effects

One major side effect of SGLT2 Inhibitor is urinary tract infection. SGLT2 Inhibitor drug filters excess blood sugar from the body in the form of urine. Frequent urination or filtering of wastes through the urethra may lead to infections. Therefore, it is imperative that patients are informed about the mechanism of the drug and its probable side effects before taking the medication. One way to avoid urinary tract infections is to maintain good hygiene   wash and clean your private areas after urination.

SGLT2 Inhibitor can also cause dehydration in the patient, as a lot of fluid is drained out of the body. Patients are advised to have a glass or two of water more than what they usually drink.

SGLT2 Inhibitor is an effective oral medication for Type 2 Diabetes mellitus. Speak with your doctor and get yourself thoroughly checked before you start taking the drug.

SGLT2 Inhibitor - Know Merits & Demerits Of It!

It is true that most people are aware of the fact that  angina  is a term which has something or the other to do with the heart. That being said, very few would be able to answer a question regarding what exactly it is, in a satisfactory manner. So would it not make sense to know more about it and become one of the few?

The term is derived from the ancient language of Latin and refers to a tightness that is felt or a squeezing of the chest. This happens when there is not enough oxygen-rich blood which is reaching the area of the heart muscle. While many people think that angina is a disease, it is actually not true to think that it is! As a matter of fact, it is a symptom of coronary artery disease. It is this disease which is the most common disease which affects the heart.

But why exactly does a person experience angina? Well, the lack of blood which is rich in oxygen occurs when it so happens that the coronary arteries become narrower than they normally should be. This generally happens due to the build-up of plaque. The condition in which this happens is known as atherosclerosis.

When it comes to the sort of people who are at a higher risk of developing angina, it can be said that those who smoke tobacco really do increase their risk, as do those who are overweight or obese and have other lifestyle diseases such as diabetes.

In order to avoid angina, the most important thing a person can possibly control is his or her lifestyle. In fact, a lot of the risk factors related to angina are attributable to the lifestyle a person chooses to lead. Cholesterol levels can be controlled if a person puts enough attention and effort in. Also, avoiding a lifestyle that is sedentary by exercise can not only help with cutting the risk of angina but also the risks of other conditions such as high blood pressure. It is ironic that high blood pressure is one of the potential signals of angina!

It is to be noted that while most people just call angina as it is, there are various types-

Stable angina is when the heart is working harder than usual and medicine helps improve this.

Unstable angina occurs even at rest and is unpredictable. It may also be a signal of a coming heart attack.

Variant and microvascular angina is relievable by medicine and is generally rare.

What Is Angina?

Cholesterol is generally regarded as something bad for the health. As a part of diet, everyone tries to avoid anything that has cholesterol in it. What needs to be understood is that not all cholesterol is bad. There is also good cholesterol, which is actually very essential for body functions. This is required for the production of essential hormones. Inadequate amounts of good cholesterol can lead to problems ranging from simple hormonal imbalances to severe issues like infertility.

The following are some food items, which contain sufficient amounts of good cholesterol and should find a place in your plate. They are essential for various body functions including hormone formation.

Avocado oil: Most oil is considered bad, but avocado oil contains about 70% of good cholesterol and should be used for its heart-healthy benefits. Being a great antioxidant, it protects the heart by reducing inflammation and by improving blood pressure. Eating whole avocado is also beneficial for the heart and the body as a whole.

Buckwheat: This whole grain is rich in many vitamins, quite a few minerals, and is a good provider of dietary fiber. It is also gluten-free and is rich in antioxidants, making it extremely cardio-friendly.

Soy: Too much saturated fat in the diet cannot be digested and the liver converts these and stores it, which adds to obesity. Soy which is a good replacement for animal fat and even dairy products can help improve cholesterol levels and prevent fat accumulation.

Salmon: This is one of the most heart-friendly food items, which is loaded with omega-3 fatty acids and good cholesterol. It lowers triglyceride levels and provides a good amount of protein for the body.

Spinach: The cholesterol which settles against the blood vessels is washed off by consuming spinach   in regular quantities at regular intervals. It is also the richest source of lutein, which is known as guardian against aging diseases including hypertension.

Go the nutty way: While most would consider nuts as rich in oils, truth is they are loaded with good cholesterol. Therefore, whether it is almonds or pecans, ground nuts or walnuts, nuts are great for the heart. They are also rich in minerals including calcium, copper, magnesium, and potassium and contain various vitamins. So about a teaspoon of chopped nuts should be on your plate on any given day.

Dark chocolate: Again, like nuts, most of us tend to avoid chocolate, but these restrictions are only for the white ones with sugar. The dark one is extremely healthy for the heart with loaded antioxidants, which prevents clogging of arteries. It is also rich in flavonoids, which are useful in controlling blood pressure and other heart diseases.

Low Cholesterol Diet - Seven Food Items To Try!!

5 natural ways to control your blood pressure

Blood pressure rises with each heartbeat and falls as your heart relaxes. The normal blood pressure should be less than 120/80 mm hg. An increase or decrease on either end can cause various problems.

Here are some of the natural ways to control your blood pressure.

1. Having a diet low in sodium

In the event of a high blood pressure, curtail the consumption of foods that are rich in sodium. However, research reveals that sometimes it is not just enough to cut down on sodium in your diet. A person suffering from high bp should consume foods rich in minerals like calcium, magnesium and potassium as well to keep his/her bp in check.

2. Drink plenty of water and curtail the consumption of alcohol

In case a person suffers from low blood pressure, it is advisable to drink plenty of water as low blood pressure is usually accompanied by bouts of dehydration, and consumption of water can help increase your blood pressure. Also, health drinks, which are rich in electrolytes, help your raise blood pressure. But one should avoid drinks that are high in sugar, and abating your alcohol consumption also helps to quite an extent.

3. Burn extra calories and exercise regularly

Blood pressure usually increases with weight. Being overweight can lead to sleep apnea, which is marked by disruptive breathing while you sleep, which in turn condition can lead to increased blood pressure. Studies have found that weight loss is one of the most effective ways to control high bp. Regular physical activity is also advised to maintain a stable blood pressure.

4. Avoid long, hot showers

The hot water in showers and spas can expand your blood vessels, which can often lead to a drop in blood pressure. A common sign of this would be dizziness and fainting while taking a bath. Therefore, for people suffering from this condition, using warm water rather than hot water is advisable.

5. Completely avoid stress

One of the contributing factors of high blood pressure is chronic stress. Stress tends to affect blood pressure in indirect ways. Many react to stress by overeating, consumption of alcohol and smoking, all of which can increase your blood pressure. Try to know what triggers your stress and take steps to avoid it.


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Related Tip: Got High Blood Pressure? Eat These 5 Foods!



5 Tricks that Control Your Blood Pressure, Naturally

The news of Sridevi's sudden and unexpected demise was a shock for the entire nation and left a number of questions in the minds of the people. However, there are multiple reasons which are under speculation and can be attributed to her death - cardiac arrest, heart attack and death due to accidental drowning. Usually, cardiac arrest and heart attack are two things which most people use interchangeably, however, there is a big difference between the two. 

Difference between cardiac arrest and heart attack: 
A cardiac arrest is far deadlier considering that it comes without a warning or any prior indication of a problem. Here, the heart just stops beating and immediate first-aid can make a lot of difference between life and death. Electrical shock is the best way to revive a patient and should be given within a few minutes of such an arrest. 

On the other hand, a person suffers a heart attack when there is a blockage in the artery which prevents the smooth flow of oxygen-rich blood from reaching the heart. It is important to note that unlike a cardiac arrest the signs of heart attack start slow and persists for long. 

A heart attack is one of the common causes of cardiac arrest, but not always it is the case. A cardiac arrest happens most commonly when the heart is receiving more than 300 impulses per minute or due to absent electrical impulses. In the first instance an electrical shock is a lifesaving technique and in the second, the patient can be treated with certain medications and a temporary pacemaker. 

Symptoms of cardiac arrest:
The symptoms of cardiac arrest are immediate and extreme.

A fainting spell or a sudden collapse
Loss of consciousness
No pulse or breathing 
Symptoms of a heart attack 

Discomfort along with chest pain 
Shortness of breath
Nausea with vomiting
Sweating
Headache and jawpain
Prevention of a cardiac arrest:
What makes this a deadly condition is that you cannot tell your risks of having one and therefore the next best thing to do is to lower your risks. 
The best way to do that is to:

Follow a diet that is balanced and nutritious
Alcohol should be consumed in moderation 
Quit smoking
Stay physically active
How can you prevent a heart attack?

Keep yourself fit and exercise regularly
Keep your cholesterol level under check 
Limit your alcohol intake 
If you are obese, control your weight
Intake a heart-friendly diet.
Now that the distinction is clear between the two, it is recommended that everyone should get themselves screened for potential heart problems on a regular basis. In case of a query or concern consult an expert and get your answers. 

Cardiac Arrest And Heart Attack - Understanding The Difference Between The Two!

Causes and Symptoms of Renal Hypertension

High blood pressure is characterized by an increased force that the blood exerts on the blood vessels when it moves through the body. Renal hypertension is a blood pressure disorder where the arteries that carry blood to the kidneys become narrow, as a result of which the blood pressure through these vessels increases.

Causes

It is caused when the arteries that supply blood to the kidney get narrow or get blocked. This can cause the kidney to release specific hormones that signal the body to retain water and sodium. This can put additional pressure on the blood vessels which leads to increased blood pressure. It can also be caused by atherosclerosis which is characterized by hardening of the arteries. Improper development of the arteries can also lead to renal hypertension.

Symptoms

The symptoms of renal hypertension are:

Feeling confused
Blurred vision
Regular headaches
Bleeding from the nose
Gradual decline in kidney function
Possible long-term damage to the kidney
Feeling lethargic and drowsy
Loss of appetite
Dryness in skin
Muscle cramps
Breathing difficulties

Treatments

The diagnostic procedure for this disorder consists of blood, urine, doppler ultrasound and CT angiography or MR angiography tests. Treatments for this disorder usually include medications to ease blood pressure. Preventive measures include modifications in lifestyle such as following a proper diet, limiting smoking, restricting sodium or salt in the diet and following an exercise regimen. Steps should also be taken to reduce stress. Yoga and meditation are highly beneficial to control the condition. Sometimes intervention is needed in the form of PTRA and stenting.

High Blood Pressure and Kidney Disease - Causes and Symptoms!

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