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Hi I am suffering from social anxiety disorder since long. My psychiatrist tried different combination of medicines but nothing worked notable. Finally, Bupron XL 300 and Panazep (25/0.5 mg) combination worked for me the most. I am taking this combination of these medicines since January 2015 and regularly since October 2015. Recently I gone through regular medical checkup and found elevated liver enzymes - Aspartate Aminotransferase (AST) and Alanine Aminotransferase (ALT), in my blood stream. I am diagnosed with no signs of Hepatitis (A/B/C), though a bit fatty liver and a small Kidney stone. I am a healthy person with no physical signs of any liver issue. I am developed little fat in my stomach in last couple of years but feel healthy. I don't drink, smoke and am pure vegetarian. I eat home-made healthy food mostly with balanced nutrition diet. I want to understand the possible causes behind my elevated liver enzymes and what could be the possible results of this situation? Is it happening due to my long-term usage of anti-anxiety medication. Do I need to stop my anti-anxiety medication? If I do so, I would be in big trouble as this will directly affect my social and working life. If this is necessary to stop medication, what are possible alternatives for me to control my social-anxiety? Please help and advise. I am worried as I have a family dependent on me only. Thanks in advance. Medicines: Bupron- Bupropion Hydrochloride Modified Release Tablets Panazep- Paroxetine Hydrochloride IP 25 mg + Clonazepam IP 0.5 mg Dosages: 1 Bupron + 1 Panazep daily in the morning with empty stomach before leaving to office Elevated Liver Enzymes: Aspartate Aminotransferase (AST or SGOT) as 169 U/L Alanine Aminotransferase (ALT or SGPT) as 113 U/L.


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