I m. Suffering from hepatitis b since last. 5. Year. Can you tell me that it can be totally cure?
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Chronic HBV infection as is attributed to your condition has the potency of complications like Hepatocellular carcinoma (HCC), Cirrhosis of liver. Or. Liver failure. In general, for HBeAg-positive patients with evidence of chronic HBV disease, treatment is advised when the HBV DNA level is at or above, 2, 000 IU/mL) and when serum alanine aminotransferase (ALT) is elevated for 3-6 months. Risk factors for progression of chronic HBV include the following: Persistently elevated levels of HBV DNA and, in some patients, alanine aminotransferase (ALT), as well as the presence of core and precore mutations Male sex Older age Family history of HCC Elevated alpha-fetoprotein (AFP) Coinfection with hepatitis D (delta) virus (HDV), hepatitis C virus (HCV), or human immunodeficiency virus (HIV) A synergistic approach of suppressing viral load and boosting the patient?s immune response with immunotherapeutic interventions is�needed. The NIH also indicates that immediate therapy is not routinely indicated for patients who have the following: Chronic hepatitis B with high levels of serum HBV DNA but normal serum ALT levels or little activity on liver biopsy (immune-tolerant phase) Low levels of or no detectable serum HBV DNA and normal serum ALT levels (inactive chronically infected/low replicative phase) Positive serum HBV DNA but not HBsAg (latent HBV infection). Currently, pegylated interferon alfa (PEG-IFN-a), entecavir (ETV), and tenofovir disoproxil fumarate (TDF) are the first-line agents in the treatment of hepatitis B disease. These are the main treatment drugs approved globally for this disease, although ongoing trials are investigating new types of medications, such as tenofovir disoproxil in combination with emtricitabine (FTC).� Liver transplant under cover of antivirals is an option as well. Interferon Alfa may cause substantial reduction of viral load in 30 - 40% of cases.
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