I am 29 years old female suffering from constipation since 6 years, taking bipolar disorder medicines since I was aged 16, taken isabgol, cremaffin plus ,duphalac, cremaffin powder, fabolite,Nityam, currently taking gudlax plus, still no permanent relief, also taken home remedies ,also leg pain due to 30-40 min sitting in Indian toilet 1-3 times a day, do not go for walking due to fear of pain in leg, career is being adversely effected, kindly advise me.