Dear Doctors, I have peyronie disease since 2011. Now my plaque is calcified and hardened and settled. I am also not having any pain in penis as earlier while erection. Howevwe, the length of my penis is shortened by 01 inch and upward bend is there. The plaque is there in top of penis to lateral side On both in mid of shaft with hourglass shape of penis while erection. I does not have any problem with ejaculation. I have read about gotu kola in many forum on internet and also in lybrate in Dr. Rahul gupta post. I want to know whether the drug is useful in such late disease condition on calcified settled plaque. Also is there any formulation of gotu kola available to apply topically on plaque on penis directly without any allergy or adverse effects? Does there any chance to soften the plaque and gain the penile length and girth back with improvement in penile bend With any other natural or ayurvedic Topical therapies? I am applying castor oil and cow ghee but did not see any improvement in long term. Waiting for positive and helpful reply! request to reply on below mentioned mail only. Thank you.