Phenytoin

Phenytoin is an anti-seizure medication. It is used to prevent partial seizures, tonic-clonic seizures, but not absence seizures. It may also be used to treat certain heart arrhythmias or neuropathic pain. It can be taken intravenously or by mouth.

Common side effects include nausea, increased hair growth, stomach pain, poor coordination, loss of appetite, and enlargement of the gums. Potentially serious side effects include self harm, sleepiness, liver problems, low blood pressure, bone marrow suppression and toxic epidermal necrolysis.

Phenytoin should be used with caution in patients having low blood pressure, heart failure, liver disease, suicidal tendencies, kidney disorders, vitamin D deficiency, diabetes and porphyria. It should not be used in people having allergy towards Phenytoin or other ingredients in the medicine or people suffering from certain heart conditions. There is evidence that use during pregnancy results in abnormalities in the baby. It appears to be safe to use during breastfeeding.

Take this medication orally as per your doctor’s prescription, with plenty of water. Avoid consumption of alcohol during the treatment. If for some reason you cannot take the medicine orally, it may be administered by a healthcare professional as an injection into a muscle or a vein, or by diluting it and giving it as a drip into a vein. The intravenous form generally begins working within 30 minutes and is effective for 24 hours. Blood levels of the patient can be measured to determine the suitable dose of the medicine.

• Trigeminal Neuralgia

• Allergy

  Not recommended in the patients with known allergy to Phenytoin.

• Nystagmus (Involuntary Eye Movement)

• Double Vision

• Sleepiness

• Anemia

• Peripheral Neuropathy

• Gingival Hyperplasia

• Increased Hair Growth

• Osteoporosis

• Is It safe with alcohol?

  Phenytoin may cause excessive drowsiness and calmness with alcohol.

• Are there any pregnancy warnings?

  Phenytoin is unsafe to use during pregnancy.
  There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.

• Are there any breast-feeding warnings?

  Phenytoin is safe to use during lactation. \nHuman studies have shown that either the drug does not pass into the breastmilk in significant amount or is not expected to cause toxicity to the baby.

• Is it safe to drive while on this medicine?

  Phenytoin may make you feel dizzy, sleepy, tired, or decrease alertness. If this happens, do not drive.

• Does this affect kidney function?

  Phenytoin is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Phenytoin may not be needed in these patients. Please consult your doctor.

• Does this affect liver function?

  Phenytoin should be used with caution in patients with liver disease. Dose adjustment of Phenytoin may be needed. Please consult your doctor.

• Missed Dose instructions

  Take the missed dose as soon as you remember. If it’s almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

• Overdose instructions

  Seek emergency medical treatment or contact the doctor if any symptoms of the overdose like uncontrolled body movements, slurred speech appear.

• India

• United States

• Japan

Below is the list of medicines, which contains Phenytoin as ingredient

• Spentoin 100mg Capsule

  Swati Spentose Pvt Ltd

• Epsotal Tablet

  Biochem Pharmaceutical Industries

• Spentoin Injection

  Swati Spentose Pvt Ltd

• Phenytal 50 mg/100 mg Tablet

  Intas Pharmaceuticals Ltd

• Phen Phen 30 mg/100 mg Tablet

  Psycormedies

Phenytoin is an anticonvulsant which is known to prevent seizures by causing a voltage-dependent block of voltage gated sodium channels. It acts by increasing sodium efflux from the neurons of the motor cortex which reduces the post-tetanic potentiation at synapses. This inhibits the cortical seizure foci from spreading to adjacent areas, thus stabilizing the threshold against hyperexcitability.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

• Interaction with Medicine

  Serenace 5Mg Injection 1Ml

  Paliris 3Mg Tablet

  Barbinol 20mg/5ml Syrup