Phenylbutazone is generally available in the form of powder. It is used to treat rheumatism, gout and similar other rheumatoid disorders in man, especially those casing musculoskeletal weakness.
Side effects of Phenylbutazone include visible water retention, nausea, vomiting, stomach cramps, dizziness, rashes, ringing in the ears and involuntary quivering. Serious adverse effects like blurred vision, allergic reactions, heart failure, depression, loss of hearing, liver problems, kidney problems and sensitivity to sunlight are rare, although they have been observed.
Medication must be stopped at the first sign of gastrointestinal tract infections, liver problems like jaundice and blood dyscrasia. Routine blood tests must be conducted every two weeks to check the count of white blood cells, as this medicine is known to have caused agranulocytosis. Therapy should be stopped immediately and remedial measures should be taken if there is any significant fall in the white blood cell count, relative decrease in the number of granulocytes, or black stools are observed. Inflammatory conditions should also be treated with specific anti-infective therapy.
Dosage varies according to the response given by the individual. Doses are reduced as symptoms regress. While treatment is begun with a relatively larger dose, it is reduced as time goes by.
Is It safe with alcohol?Parazolandin tablet may cause excessive drowsiness and calmness with alcohol.
Are there any pregnancy warnings?Parazolandin tablet may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Are there any breast-feeding warnings?Unknown. Human and animal studies are not available. Please consult your doctor.
Is it safe to drive while on this medicine?Patients may experience drowsiness, dizziness, tiredness or affect your vision, and they should avoid driving or operating machinery.
Does this affect kidney function?This medicine should be used with caution in patients with underlying kidney disease. Please Consult your doctor.
Does this affect liver function?Use of this medicine should be avoided in patients with underlying liver disease.
Below is the list of medicines, which contains Phenylbutazone as ingredient
Phenylbutazone has anti-inflammatory, analgesic and antipyretic properties and works by binding to and inhibiting the enzymes prostaglandin H synthase and prostacyclin synthase. This decreases the synthesis of prostaglandin which in turn reduces inflammation of the surrounding tissue.
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