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Overview

Ondem 4 MG Injection

Manufacturer: Alkem Laboratories Ltd
Medicine composition: Ondansetron
Prescription vs.OTC: Prescription by Doctor required

Ondem 4 MG Injection belongs to the antiemetics drug group that is used for treating nausea as well as vomiting, caused by other medical treatments such as surgery, chemotherapy and radiation. This medicine will block the chemical serotonin from releasing in your gut and your central nervous system. This will prevent vomiting and nausea. Ondem 4 MG Injection is available in four different forms that can be taken orally; tablet, disintegrating (dissolving) tablet, solution and film. It also comes in an IV (intravenous) form that can be injected to your body by a doctor. You can take it with food or without food.

Ondem 4 MG Injection can be used alone as well as in a combination with other medicines for preventing vomiting and nausea that one experiences after a surgery, chemotherapy or radiation session. This medicine, belonging to the drug group named antiemetics, blocks serotonin, a natural substance present in the body that is known to cause vomiting. Ondem 4 MG Injection is available both in tablet and liquid form. You can also take it in the IV form, when injected by a medical practitioner.

Your doctor must be informed if you are allergic to Ondem 4 MG Injection as well as other medications that block serotonin, along with any other allergies that you have. He/ She must also know about your medical history and if you had problems such as liver disease, irregular heartbeat and stomach or intestinal problems in the past. Apart from that, you must also inform the doctor if you are under any medication for depression or any psychiatric disorder.

The dosage of Ondem 4 MG Injection is decided after taking your medical condition into account and how responsive your body is to therapy. In case of children, the dose also depends on their weight and age. If you are undergoing chemotherapy, you need to take Ondem 4 MG Injection orally half an hour before your treatment starts. In case of radiation, take it 1-2 hours before the procedure of treatment begins. For preventing nausea before a surgery, it is advised to take the medication an hour before your surgery. In case you miss a dose, you can take the medication once you remember it. If it is already time for the next dose, ensure that you do not take two doses to make up for the missed dose. Overdose of Ondem 4 MG Injection can lead to severe constipation, faint spells or feeling light-headed.

The side effects of Ondem 4 MG Injection can include dizziness, drowsiness, diarrhea, constipation and headache. These side effects are usually mild in nature and goes away in a few days or 1-2 weeks. You can consult your doctor if these symptoms remain for a long time. There are some serious side effects that Ondem 4 MG Injection may have, which would require immediate medical supervision. They include:

  • Stiffness of the muscle / muscle spasms
  • Blurred vision or loss of vision temporarily
  • Fast heartbeat and sweating
  • Headache, accompanied with chest pain and a feeling of dizziness
  • Yellowing of the eyes or the skin
  • Hallucinating
  • An allergic reaction to the medication; the symptoms of which include fever, chills, rashes, difficulty in breathing and swelling of the lips, tongue, throat or face.
Nausea and vomiting
Ondem 4 MG Injection is used to treat nausea and vomiting.
Chemotherapy induced nausea and vomiting
Ondem 4 MG Injection is used to treat nausea and vomiting in cancer chemotherapy patients.
Post operative nausea and vomiting
Ondem 4 MG Injection is used to treat nausea and vomiting in post-operative patients
Avoid if the patient has a known allergy to Ondem 4 MG Injection.
Apomorphine
Avoid using Ondem 4 MG Injection with Ondem 4 MG Injection as it increases the risk of lightheadedness and loss of consciousness.
In addition to its intended effect, Ondem 4 MG Injection may cause some unwanted effects too. In such cases, you must seek medical attention immediately. This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.
Headache Major Common
Constipation Major Common
Fatigue Major Less Common
Painful urination Major Less Common
Fever Minor Common
Dry mouth Minor Common
Anxiety Minor Rare
How long is the duration of effect?
This medicine is excreted primarily in urine and the effect of this medicine lasts for a duration of 12 to 28 hours.
What is the onset of action?
The peak effect of Ondem 4 MG Injection can be observed within 30 minutes for Intravenous and 2 hours for the tablet.
Are there any pregnancy warnings?
Use of Ondem 4 MG Injection is not recommended in pregnant women.
Is it habit forming?
No habit forming tendency has been reported.
Are there any breast-feeding warnings?
No clear data is available whether Ondem 4 MG Injection is excreted through human breast milk. So, use of this drug is not recommended in breastfeeding women.
Below is the list of medicines, which have the same composition, strength and form as Ondem 4 MG Injection, and hence can be used as its substitute.
Sun Pharma Laboratories Ltd
Alkem Laboratories Ltd
Zuventus Healthcare Ltd
Dr. Reddys Laboratories Ltd
Sun Pharma Laboratories Ltd
Are there any overdose instructions?
Seek emergency medical attention or contact the doctor in case of overdose.
India
United States
Japan
Whenever you take more than one medicine, or mix it with certain foods or beverages, you're at risk of a drug interaction.
Interaction with Disease
QT Prolongation Major
Details of any heart disease, family history of an arrhythmia or any other drugs that cause QT interval prolongation (eg: Antipsychotics, Arrhythmia drugs) should be reported to the doctor. Regular cardiac function tests are to be performed if the patient is having any heart disease.
Liver Disease Moderate
Details of any liver disease (jaundice, hepatitis) or other drugs that may affect the liver (eg: TB drugs, HIV drugs) should be reported to the doctor. Regular liver function tests are to be performed if the patient is having any liver disease.
Interaction with Alcohol
Alcohol
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Lab Test
Lab
Information not available.
Interaction with Food
Food
Information not available.
Interaction with Medicine
Apomorphine Major
Use of Ondem 4 MG Injection with Apomorphine is not recommended. Replacement of the drug should be considered under the doctor's supervision. Usage of other medicines should be reported to the doctor.
Amiodarone Major
Use of Ondem 4 MG Injection with Amiodarone is not recommended as it may cause dizziness, lightheadedness, difficulty in breathing if these drugs are used together. Regular cardiac function tests are to be performed if the patient is having any heart disease. Under doctor's supervision, appropriate dose adjustments or replacement of the drug should be considered. Usage of other medicines should be reported to the doctor.
Amitriptyline Major
If these drugs are used together, the patient may experience confusion, hallucination, changes in blood pressure, fever or excessive sweating. Under doctor's supervision, appropriate dose adjustments or replacement of the drug should be considered. Usage of other medicines should be reported to the doctor.
Carbamazepine Moderate
Patient's nausea and vomiting may not subside if these drugs are taken together. Under doctor's supervision, appropriate dose adjustments or replacement of the drug should be considered. Details of other drugs should be reported to the doctor.
Phenytoin Moderate
Patient's nausea and vomiting may not subside if these drugs are taken together. Under doctor's supervision, appropriate dose adjustments or replacement of the drug should be considered. Details of other drugs should be reported to the doctor.
Cyclophosphamide Moderate
The desired effect of cyclophosphamide will not be obtained if these drugs are concurrently taken. Under doctor's supervision, appropriate dose adjustments or replacement of the drug should be considered. Details of other drugs should be reported to the doctor.
What are you using Ondem 4 MG Injection for?
Other
Nausea and vomiting
Post operative nausea and vomiting
How much was the improvement?
Excellent
Poor
How long did it take before seeing improvement?
Within 6 hours
Within a day
How frequently did you take this medicine?
Once a day
Thrice a day
How did you take this medicine?
Empty stomach
With Food
What were the side effects of this medicine?
Fatigue

Popular Questions & Answers

I have a kid for 2 years. Suddenly one morning on 08/12/2017 she started vomiting. Vomiting was continuous say 7- 8 times. She was admitted to hospital for 24 Hours. Now she is okay. During hospitalization she was given drip and various injections. Before discharge doctor has prescribed Ondem syrup and Rantac syrup. The same problem i.e frequent vomiting occurred during the month of June 2017. At that time she was admitted to ICU for 24 hours. I am not able to make out the reasons behind vomiting. Please come up with answer.

BHMS, PGDCBM, MD(AM)
Homeopath, Gurgaon
I have a kid for 2 years. Suddenly one morning on 08/12/2017 she started vomiting. Vomiting was continuous say 7- 8 t...
Your child could be severely allergic to a particular food item. Can you think of anything that was common in these 2 events. It could be egg, any sea food, any frozen snack, any new food item, some jelly/candy. Such severe bout of vomiting could also result from gastric infection. During such bouts, the body tends to reject anything that is taken orally including water which is why the vomiting continues and situation improves after the fluids and medication is given intravenously. Please think carefully and note down everything that she took in the last 48 hours before she started having vomiting. You might figure out the cause. Take care.

My Nephew he is 2 years old, he is vomiting and having fever. We have given him Meftal-P for fever.

BHMS
Homeopath, Secunderabad
My Nephew he is 2 years old, he is vomiting and having fever.
We have given him Meftal-P for fever.
Please check his fever every 3-4 hrs and check the trend of fever. Give him lots of fluids and maintain good hydration. Let him eat light food ( freshly prepared ). However, if he feels sick and not getting better , please take him to the doctor to diagnose the problem and start proper treatment.

45 days ago my mom was suffering from high blood pressure and long period knee pain issue, she is also suffering from thyroid and blood sugar issue. Within 45 days she got a wound in her armpit. When we consult doctor they told us all issues from that wound, they referred to another wound specialist. 1 day before operation her sugar down to 25 to 30. Then a sugar recovered in icu and again told to remove wound first, so we visit referred hospital where a big operation is done within her breast and armpit. Now 30 days happen of operation and we are maintaining sugar level from being down few days ago blood pressure was going normal. But now a pain and a paralysis feel in her west started. We have gone through MRI and get some Neuro doctor's doc take whole spinal, limbs mri and ncv test something like ECG and told us on mri her waist clearly showing twisted but that is from 6-7 years ago, they also told some white substances in her spinal which may be bacterial or tuberculosis infections, my mom is taking aayurved medicine for recovering paralysis effects also taking Neuro medicine Etocox 120 - 1 time Icon-od - 1 time Rb _DSR -1 time Tryptomer 8 mg Also one injection of depomedrol 80 mg one day nitro 2.6 - 2 times ranolz 500 - 1 time dilzem 30 - 2 time ondem 4 - 2 time 1 hr before meal eltroxin 100 mg - 1 time before taking food in morning Mom thinks she is getting better slowly by ayurveda but reality is that she is taking ayurveda from 20 days but condition not improve she walks 2 month before common but now after operation complete she can walk 3 trip a room by Walker, also she feels spasm all time and pain continue until she take ultracet. - 1 time myodril 8 mg - 1 time Suggested by an ortho doctors My problem is don't know how much time she will take many types of medicine and when this pain end for us. Please help sir.

MBBS, MD
Endocrinologist, Delhi
45 days ago my mom was suffering from high blood pressure and long period knee pain issue, she is also suffering from...
Your mother is having so many problems simultaneously and I think she was treated accordingly by qualified doctors, have faith inyour Doctors, it will take time to recover.

Hi I recently gave birth to a baby girl just 8 days old. My question and worry about is anesthesia given to me during Cesarean and side affects. That day as human mistake I unknowingly had a sip of water before anesthesia or antibiotics were given .so said the said to doctor they gave ondem injection and one gastric before anesthesia was given and later due to a bad or untrained nurse I was given an antibiotic on third day as usual on wrist which she injected forcefully into the nerve through a pipe. It pained like hell. I almost screamed to peaks. The antibiotic did not go into the nerve. It blocked and swelled the wrist. It took three days to reduce the swelling on its own. My right head side full sweating. Due to humidity. And it's cold entire face on right. And even on eight side neck. My legs started swelling .I don't think it's water that caused swelling. Can you say why these many changes in this Cesarean.

MD - Anaesthesiology, DNB, MBBS, Diploma In Aesthetic Medicine
Pain Management Specialist, Amritsar
Hi I recently gave birth to a baby girl just 8 days old. My question and worry about is anesthesia given to me during...
lybrate-user just relax nothing to worry. There is no problem of water you took if you were given injection in the back (spinal anaesthesia) problem could have come if general anaesthesia was required. Now since it's 8 days post caesarean. Nothing to worry. The pain you had could be due to blocked vein which sometimes open with pain or some antibiotics are painful to inject. Don't think of worst that could happen rather feel good that you are are ok & safe.
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Table of Content

About Ondem 4 MG Injection
When is Ondem 4 MG Injection prescribed?
What are the contraindications of Ondem 4 MG Injection?
What are the side effects of Ondem 4 MG Injection?
Key highlights of Ondem 4 MG Injection
What are the substitutes for Ondem 4 MG Injection?
What are the dosage instructions?
Where is the Ondem 4 MG Injection approved?
What are the interactions for Ondem 4 MG Injection?