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Overview

Nitrocontin 6.4 MG Tablet

Nitrocontin 6.4 MG Tablet

Manufacturer: Modi Mundi Pharma Pvt Ltd
Medicine composition: Glyceryl Trinitrate
Prescription vs.OTC: Prescription by Doctor required

Nitrocontin 6.4 MG Tablet is a kind of nitrate that is mainly prescribed for chest pains such as angina. Also known as Nitroglycerin, it came into medical use in 1878. It is used to cure heart failure, high blood pressure, relief from chronic anal fissures and control of blood flow during the course of an operation. This is available as a tablet, spray, ointment and as an injection. Nitrocontin 6.4 MG Tablet helps to widen your blood vessels allowing the increasing flow of blood to your heart muscle.

Side effects of using Nitrocontin 6.4 MG Tablet include headaches, dizziness, low blood pressure, nausea, diarrhea, lightheadedness, irregular or fast heartbeat, stomach pain, restlessness, anxiety, sweating. Serious allergic reactions are trouble breathing, skin rashes or swelling. In case you develop any of the allergic reactions notify your health care provider.

Certain precautions that you should ensure before taking this medication include informing you doctor of the following conditions:

  • If you are pregnant or are planning to become pregnant.
  • If you are breastfeeding a baby.
  • If you have a case of low blood pressure.
  • If you have low levels of blood or low levels of oxygen.
  • If you have glaucoma.
  • If you are allergic to any medicine.
  • If you have had a recent heart attack.
  • If you have haemorrhoids.
  • If you have migraines or frequent headache problems.
  • If you have a liver or a kidney problem.

The dosage for Nitrocontin 6.4 MG Tablet depends on your gender, height, weight, medical history and overall health. The tablet or the spray is prescribed for short-term issues and has to be taken sublingually. Each tablet is about 500 micrograms of Nitrocontin 6.4 MG Tablet. The ointment should be applied within a gap of three to four hours. In case of extreme illness from taking this medicine inform your physician immediately. Nitrocontin 6.4 MG Tablet should be stored in a cool and dry place, out of the reach of children. It can be stored up to eight weeks after which it is recommended that you get a fresh batch.

Angina pectoris
This medicine is used for the prevention and treatment of chest pain caused due to reduced blood and oxygen flow to the heart. Angina may be stable (happens after exertion and is short lasting) or unstable (happens in an unpredicted manner and is more severe and long lasting)
Hypertension during surgeries
This medicine is used to control increased blood pressure while a major surgical procedure is performed on a patient.
Chronic anal fissures
This medicine is also used rectally to relieve pain caused due to anal fissures or tears on the wall of the rectum.
This medicine is not recommended for use if you have a known history of allergy to glyceryl trinitrate or any nitrate-containing medicines.
This medicine is not recommended for use if you have anemia or low levels of hemoglobin in the blood.
This medicine is not recommended for use if you have an eye condition called closed angle glaucoma.
Obstructive heart disease
This medicine is not recommended for use if you have a condition where the blood vessels in the heart have blockage due to swelling or narrowing.
Head trauma/ Increased intracranial pressure
This medicine is not recommended for use in patients having a severe head injury or the pressure in the brain is elevated.
Medicine for erectile dysfunction
This medicine is not recommended for use if you are taking medicines for the treatment of erectile dysfunction. One of the most commonly used medicines for this condition is viagra (sildenafil),
Heparin
This medicine is not recommended for use if you are being given Heparin for correcting any blood clotting disorder.
In addition to its intended effect, Nitrocontin 6.4 MG Tablet may cause some unwanted effects too. In such cases, you must seek medical attention immediately. This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.
Difficulty in breathing Major Rare
Dizziness and fainting Major Less Common
Swelling of the eyes, ears, and inside of nose Major Less Common
Nausea and Vomiting Minor Less Common
Headache Minor Common
Coma Major Rare
Seizures Major Rare
Change in heart rate Major Rare
Excessive sweating Moderate Less Common
Flushing Moderate Less Common
Severe chest pain Major Less Common
Blurred vision Moderate Less Common
Pale and clammy skin Moderate Less Common
How long is the duration of effect?
The effect of this medicine lasts for an average duration of 12 hours upon oral administration. This time duration is subject to variations depending on the route of administration.
What is the onset of action?
The effect of this medicine can be observed within an hour of oral administration. However, this time is subject to vary depending on the route of administration. The effect of this medicine can be observed within minutes of intravenous administration and takes about 30-60 when administered topically.
Are there any pregnancy warnings?
The use of this medicine by pregnant women is not recommended unless necessary and the benefits outweigh the risks involved with use. Consult your doctor before using this medicine.
Is it habit forming?
No habit forming tendencies were reported.
Are there any breast-feeding warnings?
The use of this medicine is not recommended by breastfeeding women unless necessary. Consult your doctor before using this medicine.
Below is the list of medicines, which have the same composition, strength and form as Nitrocontin 6.4 MG Tablet, and hence can be used as its substitute.
Emcure Pharmaceuticals Ltd
Abbott Healthcare Pvt. Ltd
Intas Pharmaceuticals Ltd
Mankind Pharmaceuticals Ltd
Wockhardt Ltd
Missed Dose instructions
Contact your doctor immediately if you miss a scheduled dose of this medicine.
Overdose instructions
Contact your doctor immediately if an overdose with this medicine is suspected. Symptoms of an overdose may include headache, confusion, fever, change in the heart beat, nausea, vomiting etc.
India
United States
Japan
Whenever you take more than one medicine, or mix it with certain foods or beverages, you're at risk of a drug interaction.
Interaction with Disease
Acute myocardial infarction Major
This medicine should be used with extreme caution in patients suffering from a heart attack or heart failure. The use should be preceded by suitable clinical examinations to ensure safe and effective use.
Anemia Major
This medicine should be used with caution in patients suffering from anemia as the risk of adverse effects are significantly high. Appropriate dose adjustment and safety monitoring must be done in such cases.
Hypotension Major
This medicine should be used with extreme caution in patients who have low blood pressure. The risk of further lowering of blood pressure and associated adverse effects are significantly high.
Interaction with Alcohol
Ethanol Minor
Avoid the use of alcohol while taking this medicine.
Interaction with Lab Test
Lab
Information not available.
Interaction with Food
Food
Information not available.
Interaction with Medicine
Amitriptyline Moderate
Use of this medicine along with amitriptyline may cause some serious side effects and hence should be used with caution. Contact your doctor if you experience a headache, dizziness, fainting or change in heart rate while using these medicines together.
Amlodipine Moderate
Report the use of amlodipine or any other medicine taken for lowering the blood pressure to the doctor. You may need a dose adjustment and more frequent monitoring of blood pressure levels while using these medicines together.
Prilocaine Major
Use of this medicine with prilocaine may cause severe adverse effects. Hence they should not be used together. Your doctor may determine the best course of treatment in such cases. Do not stop the use of any medicine without consulting your doctor.
Sildenafil Major
Use of this medicine with sildenafil or any other medicine used for erectile dysfunction is not recommended. The risk of rapid fall in blood pressure and associated complications are significantly high when these medicines are taken together.
Riociguat Major
Use of this medicine in combination with riociguat is not recommended as the risk of adverse effects are significantly high while using them together. Report any incidence of a rapid fall in blood pressure, fainting, flushing to the doctor immediately.
Dihydroergotamine Moderate
Report the use of either of the medicine to the doctor. You may require a dose adjustment and more frequent monitoring to safely use these medicines together.
Heparin Moderate
Report the use of either of the medicine to the doctor. You may need an adjusted dose of heparin and clinical monitoring to safely use these medicines together. Any sign and symptom indicative of a blood clot like chest pain, difficulty in breathing, sudden loss of vision, pain and swelling in the extremities should be reported to the doctor immediately.

Popular Questions & Answers

In Nov 2015 I have undergone angioplasty with 2 stents and prescribed with medicines such as storvas, nitrocontin, plavix, cardace, etc. And advised to go for another angio for one more block. Except at the time of overstrain, otherwise works normal everyday. Recently gone for checkup and except treadmill all other tests like ECG, Echo, Blood etc. Are normal. Is it necessary to for going for another angio or is there any additional medicine that can reduce the block. Pls advise. Tks.

Diploma in Obstetrics & Gynaecology, MBBS
General Physician, Delhi
In Nov 2015 I have undergone angioplasty with 2 stents and prescribed with medicines such as storvas, nitrocontin, pl...
You have symptoms only when you overstrain and difficulty in doing tmt test looks like some block has developed again you can try conservative treatment like mild exercises, yoga, eating seasonal vegetables and fruits, less stress, less or no exposure to pollution, inhaling fresh oxygen through green plants in home, keeping a disciplined lifestyle all of these collectively manage to open up collateral blood vessels of heart which were lying low and unopened, collatetals start functioning and it's as good as nature doing a bypass surgery do observe and take care of nutrition, exercise and other factors.
2 people found this helpful

Sir, My Father is Serious Heart Patient, referred to CABG from Cardiovascular on dated 02.03.2017, Due to 3 Arteries Blocked almost 70%, with High sugar though Insulin continuing. Sergant Told that after 1 month if sugar reduced then we think about CABG. Yesterday Blood sugar test has been done after 7 Days since Taking insulin, result came:- Fasting:- 157, P.P:- 112. Ejection factor (E.F) after ECO doppler Test it is found that EF=30. Eurik Asid:- 5.8, Some medicine Has been Prescribed By Cardiologist for 30 Days, These are mentioned Below:- SORBITRATE 5 MG TAB 50'S BASALOG 100IU INJ 5 ML INSUGEN R 40IU INJ 10 ML TIDE PLUS 20 MG TAB 10'S TIDE PLUS 20 MG TAB 10'S CARDACE 1.25 MG TAB 10'S STORVAS 80 MG TAB 10'S CLOPITAB A 75 MG CAP 15'S CORDARONE 100 MG TAB 10'S CORDARONE 100 MG TAB 10'S NITROCONTIN 2.6 MG TAB 30'S (BOTTLE) NITROCONTIN 2.6 MG TAB 30'S (BOTTLE) RANOLAZ 500 MG TAB 10'S RANOLAZ 500 MG TAB 10'S TRIVEDON Mr. TAB 10'S METOROSS 25 TAB 10'S. So I need some Guideline about the daily sugar free food chart, if you provide me. And also told me the next treatment steps how I can proceed after One Month, Please Guide me from Your Valuable Advice. And I want to Know the cost of CABG and how much cost? With Warm Regards,

MBBS, PGDCC
Cardiologist, Delhi
Sir, My Father is Serious Heart Patient, referred to CABG from Cardiovascular on dated 02.03.2017, Due to 3 Arteries ...
Hi welcome, Blockage in all three arteries with reduced heart function& hhistory of cardiac arrest is a serious thing. He will definitely need a by pass surgery (CABG). The risk of the surgery will be higher than a normal patient with blockage in all three arteries. Diabetes control is definitely a very important thing. About medication, dose of cardace could be increased as per bp. Another very important medication (beta blocker) should be added to the treatment. Both the cardace & beta blocker are very very important for such patients. I could be of more help if you could send me the echo & Angio report. Thanks & take care.
1 person found this helpful

Hi mom, 60 yrs, diabetic patient, has 4 blocks in heart artery (via angiogram, doctor suggested for CAB, bypass surgery. But we thought of trying ayurvedic. She is taking the mixture of lemon, ginger, garlic juices with vinegar and honey in empty stomach. She is taking it for 15 days now. Nothing much changes. In fact, she is feeling very tired and getting leg pain as well very frequently. She is taking medicine given by doctor as well. Please suggest me what to I will attach reports.

M.D. Consultant Pathologist, CCEBDM Diabetes, PGDS Sexology USA, CCMTD Thyroid, ACDMC Heart Disease, CCMH Hypertension, ECG
Sexologist, Sri Ganganagar
Hi mom, 60 yrs, diabetic patient, has 4 blocks in heart artery (via angiogram, doctor suggested for CAB, bypass surge...
You send the reports. Go for bypass surgery .donot wait. It is best time as age is 60 yrs. Only. Take statins, nitrocontin, control diabetes and b.p. Avoid fatty diet. Prevent your mother from cold waves. Keep isordil with you. In emergency use sublingual. Any more ask on line.

I have just been detected with triglyceride of 308, HDL of 32, LDL of 115, VLDL of 61. My doctor has prescribed Rozavel F. I am also a diabetic patient. My question is whether Rozavel F or Nitrocontin 2.6 is better medicine to control triglycerides? Please advise.

MBBS, MD - Internal Medicine, DM - Cardiology, Cardiac Device Specialist (CCDS - Physician )
Cardiologist, Delhi
I have just been detected with triglyceride of 308, HDL of 32, LDL of 115, VLDL of 61. My doctor has prescribed Rozav...
Nitrocontin is not a cholesterol control agent, it is a anti-hypertensive and anti-anginal and has no impact on lipid profile. Rozavel F is the cholesterol control drug.
2 people found this helpful

Popular Health Tips

Saving Kit in Case Of Heart Attack

MD, MBBS, CCD
General Physician, Jabalpur
Saving Kit in Case Of Heart Attack

Life saving kit in case of mi / heart attack 

A very handy kit which may protect a person from dying of sudden heart attack.
It should have following items:-
 A. Tab disprin / aspirin 4

 B. Tab glyceryl trinitrate 4

 C. G. Tri nitrate skin patch-1

 If one feels sudden tightness and pain in centre of chest, radiating to left arm or both sides of neck, accompanied by sweating and uneasiness, one is likely to be in a state of heart attack.* 

Following measures must be taken immediately:-
 A. Keeping one glyceryl tri itrate tablet under the tongue.
 B. Chewing one disprin tablet.
 C. Pealing of and sticking the skin patch on left side of chest.

 Can definitely save a person from dying immediately of a heart attack.

Every person who is at risk and above 40 years should carry this.

Dr. Rahul kewalkumar.
Mbbs, md.

7 people found this helpful

What is the Difference Between an Antiperspirant and a Deodorant?

MBBS, MD (Skin & V.D. MAMC) - Dermatology
Dermatologist, Delhi
What is the Difference Between an Antiperspirant and a Deodorant?

Deodorants and antiperspirants are items of regular use all over the world. You would never want to smell bad or have sweat stains under your armpits. Hence, after using a deodorant or an antiperspirant you usually stick to it and keep on using it continuously. There is a major confusion regarding deodorants and antiperspirants, and it is important to know the major difference between these two similar items of everyday use.

Deodorant-

Deodorant serves the function of preventing unwanted and unpleasant odour from our body. Deodorants do not prevent sweating. Body odour is caused due to the bacterial breakdown of sweat. The ingredients of a deodorant are designed especially for the elimination of the smell caused by bacteria.

The common ingredients of a deodorant are :

  • Water

  • Sodium stearate

  • Organic aloe vera juice

  • Witch hazel water

  • Glyceryl laurate

  • Fir needle oil

  • Chamomile flower aqueous extract

  • Hops [CO2] extract – helps eliminate the odour

  • Caprylic/capric triglyceride

  • Ascorbic acid

  • Silica shell

  • Organic Lemongrass Oil

Antiperspirants-

Antiperspirants are different from deodorants, and they are designed in such a way that the body produces lesser sweat. This is done by blocking sweat from reaching the skin. The ingredients present in antiperspirants, especially aluminum, block the pores on the skin and do not allow sweat to pass through them. When an antiperspirant is applied to the skin, the aluminum salts get dissolved in the sweat under the armpit. The dissolved aluminum forms a gel, which acts like a plug on the sweat glands or pores on the skin. This stops sweat secretion. Aluminum is, however, a cancer-causing factor and may also lead to Alzheimer’s disease. Several forms of aluminum present in some antiperspirants leave yellow stains on clothes as a result of mixing with sweat.

The primary ingredients of antiperspirants are:

  1. Aluminum Zirconium Trichlorohydrex.

  2. Dimethicone.

  3. Tribehenin.

  4. Artificial fragrance.

  5. C18 36 Acid Triglyceride.

People are often confused as to what to use among deodorants and antiperspirants. This depends totally on your personal choice, but it is recommended to use a product which incorporates natural ingredients instead of using chemicals such as aluminum. Hence, deodorants are considered to be safer for everyday use. However, several artificial dyes and fragrances are used as ingredients in both deodorants and antiperspirants, which cause reactions on the skin. Allergies and skin irritation also occur sometimes as a result.

6265 people found this helpful

Uterine Fibroids - How They Can Be Managed?

Fellowship in Gynae Endoscopy, FMAS, DNB, DGO, MBBS
Gynaecologist, Delhi
Uterine Fibroids - How They Can Be Managed?

The uterine fibroids are one of the most common gynecologic problems, with over 40-50% of women having them at some point in their life. The number and size of the fibroids, the age of onset, associated symptoms like dysfunctional bleeding and pelvic pain will determine the management of fibroid. The following is a series of management measures, starting from the most conservative to the most invasive. 

1. Wait and watch: In women who are asymptomatic, it is best to watch them for the development of symptoms without any intervention. Also, in women nearing menopause, it is best to just watch the fibroids as they just shrink once menstruation ceases. 

2. Medical therapy: In some women, menstrual cycles could be heavy or irregular and require hormonal replacement. They could also have occasional pain, and so may require painkillers. 

  1. Tranexamic acid is a non-hormonal medication that can be used on heavy bleeding days only to ease the heavy menstrual flow. 
  2. Nonsteroidal anti-inflammatory drugs (NSAIDs) are useful in pain control. Iron and vitamin supplements are also useful in managing anemia and weakness associated with heavy bleeding. 
  3. Oral contraceptives and/or progestins are also used to control abnormal menstrual bleeding. They do not have any effect on fibroid size though. 
  4. Progestin could also be delivered through an intrauterine device (Mirena) to relieve heavy bleeding and prevent pregnancy
  5. Gonadotropin-releasing hormone (Gn-RH) agonists: They block the production of oestrogen and progesterone, and so induce a temporary postmenopausal state. This can also be used to shrink the fibroid so it is easier to remove it surgically. This is not used for more than 3 to 6 months as they can cause hot flashes and bone loss. 
  6. Newer drugs like Mifepristone and Ulipristal acetate are being used to shrink the size of fibroids. 

3. Noninvasive procedure: MRI-guided focused ultrasound surgery is when the women are inside the MRI scanner and an ultrasonic transducer is used for treatment. The exact location of the fibroids are identified and sound waves are used to destroy the fibroid. Done on an outpatient basis, it is safe and effective. 

4. Minimally invasive procedures: Uterine artery embolization is where the arterial supply is cut off to reduce fibroid growth. Myolysis is where laparoscopically heat or cold waves are used to lyse off the fibroids. Endometrial ablation is where the uterine lining is destroyed through high-intensity heat or cold waves. 

5. Invasive procedures: Abdominal or Laparoscopic myomectomy is where the fibroids are removed through an abdominal incision or keyhole surgery. If fibroids are extensive and completed family, hysterectomy is the choice of treatment. Given their high incidence, fibroids require management based on symptoms, age, and other considerations as discussed and decided between the patient and the doctor.

2639 people found this helpful

4 Ways To Manage Endometriosis!

EMDR, FRCOG (LONDON) (Fellow of Royal College of Obstetricians and Gynaecologists), MFSRH , Diploma in psychosexual therapy, Medical diploma in clinical Hypnosis, Diploma in Evidence Based Healthcare, DNB (Obstetrics and Gynecology), MD - Obstetrics & Gynaecology, MBBS
Gynaecologist, Pune
4 Ways To Manage Endometriosis!

When tissues that usually grow inside the uterus, start growing outside the organ, it is called endometriosis. Painful periods, pain during sex, pain while urinating or bowel movements, extreme bleeding, fatigue, infertility, diarrhea, bloating and nausea are some of the symptoms of endometriosis.

Treating endometriosis usually depends on the following factors

  1. Age
  2. Severity of symptoms
  3. Severity of the disease
  4. Future plans for children

Depending on these the doctor might opt for any of the following treatments

  1. Medication for Pain: If the symptoms are mild, then the doctor will prescribe some pain killers like Nonsteroidal anti-inflammatory drugs. 
  2. Hormone Therapy: Hormone therapy is effective, but once you stop them, your symptoms may come back. Some of the hormone therapies include: 
    • Hormonal Contraceptives: Birth control pills, vaginal rings and patches are useful in controlling the hormones that are responsible for tissue build-up outside the uterine cavity. 
    • Medroxyprogesterone: This drug stops menstruation, which in turn stops the tissue build-up and put an end to all the symptoms. But on the other hand, gaining weight, low bone production and depression are some of the common effects of this drug. 
    • Gonadotropin-releasing hormone (Gn-RH) antagonists and agonists: Hormones that stimulate ovaries are blocked by these. They bring down oestrogen levels and hence prevent menstruation. 
    • Danazol: This drug prevents menstruation and symptoms of endometriosis by blocking the hormones that stimulate the ovaries. However, Danazol may not be a favourable option because of its side effects. The drug should be avoided during pregnancy.
  3. Conservative Surgery: If you are trying to get pregnant, but you already suffer from endometriosis, then removing endometriosis surgically is a viable solution. Your uterus and ovaries will be preserved, which might increase your chances of becoming pregnant. Even suffering from severe pain might find relief from conservative surgery. 
  4. Hysterectomy: In extreme cases, the only way to deal with the symptoms is to completely remove the uterus, ovaries and cervix. Since a hysterectomy means you cannot have children, it is kept as the last option for women in their reproductive age. If you wish to discuss about any specific problem, you can consult a gynaecologist.
5 people found this helpful

Chronic Nephritis - How To Cope With It?

DNB (Nephrology), MD, MBBS
Nephrologist, Delhi
Chronic Nephritis - How To Cope With It?

Chronic nephritis is a type of Glomerulonephritis (GN). In this condition, irritation takes place in the Glomeruli, which are parts in your kidneys comprising tiny blood vessels. These knots of vessels filter your blood and remove excess fluids from the body. In case your glomeruli are harmed, your kidneys will quit working properly and you can suffer from kidney failure. It is a very serious illness that can be life threatening and requires immediate medical intervention.

The condition is also called nephritis. There can be both acute and chronic nephritis. The chronic type of GN can take several years to develop with almost no obvious symptoms. This can cause irreversible harm to your kidneys and also prompt complete kidney failure.

Causes and risks:
A hereditary condition can once in a while cause chronic nephritis. It happens in young men with poor vision and poor hearing. Persistent and untreated conditions may also bring about chronic nephritis. A history of cancer in the family may likewise put you at danger. Having acute nephritis may make you more prone to build up chronic nephritis later on. Being exposed to some hydrocarbon solvents may build the danger of chronic nephritis. Chronic nephritis does not generally have a clear-cut cause. About 25% of individuals with this condition have no history of kidney diseases.

Symptoms:
A few symptoms of chronic nephritis include:

  1. Blood or abundance protein in your urine
  2. Hypertension
  3. Swelling in lower legs
  4. Continuous urination during evenings
  5. Bubbly or frothy urine (from abundance protein)
  6. Stomach pain
  7. Continuous nosebleeds


Treatment:
Depending upon the symptoms of the problem, the treatment might be distinctive. Some of the ways it can be dealt with are:

  • Controlling hypertension, particularly if that is the hidden cause for the problem. Circulatory strain might be difficult to control when your kidneys are not working properly. If so, your specialist may prescribe pulse medicines, including angiotensin-changing over catalyst inhibitors. Some of these medicines include Captopril, Lisinopril and Perindopril.
  • Your specialist may likewise recommend angiotensin receptor blockers (ARBs). Some of these may include Losartan, Irbesartan and Valsartan.
  • Another technique to reduce immune-triggered aggravation is plasmapheresis. This procedure expels the liquid part of the blood (plasma) and replaces it with intravenous (IV) liquids or donated plasma (without any antibodies).

For chronic GN, you will have to decrease the level of protein, salt and potassium in your diet. Also, you should observe the amount of fluid you drink. Calcium supplements might be suggested and you may need to take diuretics to lessen swelling. Not surprisingly, check with your general physician or kidney specialist for rules about dietary restrictions or food. In case your condition worsens and causes kidney failure, you may need dialysis. This is a technique where a machine filters your blood. In the end, you may require a kidney transplant. If you wish to discuss about any specific problem, you can consult a Nephrologist.

2088 people found this helpful

Table of Content

About Nitrocontin 6.4 MG Tablet
When is Nitrocontin 6.4 MG Tablet prescribed?
What are the contraindications of Nitrocontin 6.4 MG Tablet?
What are the side effects of Nitrocontin 6.4 MG Tablet?
Key highlights of Nitrocontin 6.4 MG Tablet
What are the substitutes for Nitrocontin 6.4 MG Tablet?
What are the dosage instructions?
Where is the Nitrocontin 6.4 MG Tablet approved?
What are the interactions for Nitrocontin 6.4 MG Tablet?