Nitract 2.5 MG Capsule SR
Nitract 2.5 MG Capsule SR is prescribed for the treatment of angina pectoris. The I.V. is used for congestive heart failure (especially when associated with acute myocardial infarction). It is also helpful in treating pulmonary hypertension.
During hypertensive emergencies occurring perioperatively (especially during cardiovascular surgery), this medication is primarily prescribed to make it go away. Nitract 2.5 MG Capsule SR is a kind of nitrate also known as Nitroglycerin, it came into medical use in 1878.
It is used to cure heart failure, high blood pressure, relief from chronic anal fissures and control of blood flow during the course of an operation. Nitract 2.5 MG Capsule SR helps to widen your blood vessels allowing the increasing flow of blood to your heart muscle.
Side effects of using Nitract 2.5 MG Capsule SR include headaches, dizziness, low blood pressure, nausea, diarrhea, lightheadedness, irregular or fast heartbeat, stomach pain, restlessness, anxiety, sweating. Serious allergic reactions are trouble breathing, skin rashes or swelling.
In case you develop any of the allergic reactions notify your health care provider. Certain precautions that you should ensure before taking this medication include informing you doctor of the following conditions if you have or are:
- Pregnant or are planning to become pregnant.
- Breastfeeding a baby.
- A case of low blood pressure.
- Low levels of blood or low levels of oxygen.
- Allergic to any medicine.
- Recent heart attack.
- Migraines or frequent headache problems.
- Liver or a kidney problem.
The dosage for Nitract 2.5 MG Capsule SR depends on your gender, height, weight, medical history and overall health. Nitract 2.5 MG Capsule SR should be stored in a cool and dry place, out of the reach of children. It can be stored up to eight weeks after which it is recommended that you get a fresh batch.
Do not change brands without consulting prescriber. Do not discontinue abruptly. Keep medication in original container, tightly closed. Take medication while sitting down and use caution when changing position (rise from sitting or lying position slowly).
Nitract 2.5 MG Capsule SR may cause dizziness. use this medicine with caution when driving or engaging in hazardous activities until response to drug is known. If chest pain is unresolved in 15 minutes, seek emergency medical help at once. Report acute headache, rapid heartbeat, unusual restlessness or dizziness, muscular weakness, or blurring vision.
Concomitant use of sildenafil (Viagra®) may precipitate acute hypotension, myocardial infarction, or death. Nitrates used in right ventricular infarction may induce acute hypotension. Nitrate use in severe pericardial effusion may reduce cardiac filling pressure and precipitate cardiac tamponade.
In the management of heart failure, the combination of isosorbide dinitrate and hydralazine confers beneficial effects on disease progression and cardiac outcomes.
May need to use nitrate-free interval (10-12 hours/day) to avoid tolerance development; gradually decrease dose in patients receiving NTG for prolonged period to avoid withdrawal reaction.
The primary use of this medication is as follows:
Hypertension During Surgeries
Chronic Anal Fissures
Congestive Heart Failure
How long is the duration of effect?The effect of this medicine lasts for an average duration of 12 hours upon oral administration. This time duration is subject to variations depending on the route of administration.
What is the onset of action?The effect of this medicine can be observed within an hour of oral administration. However, this time is subject to vary depending on the route of administration. The effect of this medicine can be observed within minutes of intravenous administration and takes about 30-60 when administered topically.
Are there any pregnancy warnings?The use of this medicine by pregnant women is not recommended unless necessary and the benefits outweigh the risks involved with use. Consult your doctor before using this medicine.
Is it habit forming?No habit forming tendencies were reported.
Are there any breast-feeding warnings?The use of this medicine is not recommended by breastfeeding women unless necessary. Consult your doctor before using this medicine.
Is It safe with alcohol?It is unsafe to consume alcohol along with this medicine. Kindly consult your doctor before taking it.
Is it safe to drive while on this medicine?This medicine affects the alertness of the patient. Thus driving must be avoided while taking this medicine.
Does this affect kidney function?This medicine is probably safe to be used in patients with kidney disease. Adjustment of dose might not be needed. Kindly consult your doctor before taking it.
Does this affect liver function?Limited information is available regarding its use in patients with liver disease. Kindly consult your doctor before taking it.
Missed Dose instructionsContact your doctor immediately if you miss a scheduled dose of this medicine.
Overdose instructionsContact your doctor immediately if an overdose with this medicine is suspected. Symptoms of an overdose may include headache, confusion, fever, change in the heart beat, nausea, vomiting etc.
This medication works by getting converted to nitric oxide (NO) free radicals in the body which relax the blood vessels and reduces the load on the heart. This results in improved blood flow and reduced oxygen demand.
Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.
Interaction with Alcohol
Interaction with Lab Test
Interaction with Medicine
- Alteplase (tissue plasminogen activator) has a lesser effect when used with I.V. nitroglycerin; avoid concurrent use.
- Ergot alkaloids may cause an increase in blood pressure and decrease in antianginal effects; avoid concurrent use.
- Heparin's effect may be reduced by I.V. nitroglycerin. May affect only a minority of patients.
- Sildenafil potentiates the hypotensive effects of nitrates; concurrent use is contraindicated.
Interaction with Food
Interaction with Disease
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Nitroglycerin-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 4 June 2022].Available from:https://druginfo.nlm.nih.gov/drugportal/name/nitroglycerin
Nitroglycerin-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 4 June 2022].Available from:https://go.drugbank.com/drugs/DB00727
NITROGLYCERIN solution-DailyMed [Internet].dailymed.nlm.nih.gov 2022 [Cited 4 June 2022].Available from:https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=NITROGLYCERIN
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