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Prescription vs.OTC: Prescription by Doctor required
Last Updated: December 20, 2021

Naproxen is known to be a pain relieving medicine. It is a non-steroidal anti-inflammatory drug which works by reducing the hormones causing pain and inflammation in the body. by conditions such as ankylosing spondylitis, arthritis, tendinitis, gout, bursitis or menstrual cramps.

On using this medicine some side effects like stomach upset, nausea, vomiting, heartburn, drowsiness, headache may occur. Serious side effects may include easy bruising or bleeding, painful swallowing, ringing in the ears, signs of kidney problems, mood changes, unusual tiredness, swelling of the ankles, feet and hands, unexplained stiff neck, unexplained weight gain and vision changes.

To ensure this medicine is safe for you tell your doctor if you have :

Take this medicine by mouth as instructed by your doctor, usually 2 or 3 times in a day. Remember to not lie down for a minimum of 10 minutes after taking it. To prevent stomach upset, take this drug with milk, food or an antacid.

This medicine is generally considerably safe but it is not suitable for all. To reduce your risk of side effects, start the medication at the lowest effective dose for a short period of time. Take a higher dosage if needed, after consulting with a doctor.

Symptoms of Naproxen overdose include drowsiness, heartburn, vomiting, CNS depression, leukocytosis, renal failure. Management of a nonsteroidal anti-inflammatory drug (NSAID) intoxication is primarily supportive and symptomatic; fluid therapy is commonly effective in managing the hypotension that may occur following an acute NSAID overdose, except when this is due to an acute blood loss.

Seizures tend to be very short-lived and often do not require drug treatment; although, recurrent seizures should be treated with I.V. diazepam; since many of the NSAIDs undergo enterohepatic cycling, multiple doses of charcoal may be needed to reduce the potential for delayed toxicities.

Take this medication exactly as directed; do not increase dose without consulting prescriber. Do not crush tablets or break capsules. Take with food or milk to reduce GI distress. Maintain adequate fluid intake (2-3 L/day of fluids unless instructed to restrict fluid intake).

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Orthopedic Doctor before using this medicine.

The medication is primarily used for the following conditions:

  • Mild To Moderate Pain

  • Pain Relief

  • Hypersensitivity

Below are some of the common side effects of this medicine:

  • Is It safe with alcohol?

    Taking this medication with alcohol can increase the risk of stomach bleeding caused by naproxen.
  • Are there any pregnancy warnings?

    This medication may be unsafe to use during pregnancy.
    Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
  • Are there any breast-feeding warnings?

    Unknown. Human and animal studies are not available. Please consult your doctor.
  • Is it safe to drive while on this medicine?

    Do not drive, operate machinery.
  • Does this affect kidney function?

    This medicine should not be given in renal failure.
    Caution should be used in patients with severe renal impairment.
  • Does this affect liver function?

    Reduce dose to 50% in patients with liver disease.
  • How long is the duration of effect?

    The effect of this medicine will last for an average period of 8 -12 hours.
  • What is the onset of action?

    The effect of this medicine will be observed within 1 hour after its administration.
  • Is it habit forming?

    No habit forming tendency has been reported.
  • Are there any overdose instructions?

    Seek emergency medical treatment or contact the doctor in case of an overdose.
  • Are there any missed dose instructions?

    If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Below is the list of medicines, which contains Naproxen as ingredient

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This medication belongs to the class of NSAIDs (Non-Steroidal Anti Inflammatory Drug) that inhibit prostaglandin synthesis by non selectively impeding the COX -1 and COX -2 enzymes. This helps in alleviating inflammation, as prostaglandin is a regulator for inflammation in muscles.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

  • Interaction with Alcohol

    Alcohol consumption is not advised while consuming this medication as it can result in stomach bleeding.
  • Interaction with Medicine

    Increased toxicity:

    • Naproxen could displace other highly protein bound drugs, such as oral anticoagulants, hydantoins, salicylates, sulfonamides, and sulfonylureas.
    • Naproxen and warfarin may cause a slight increase in free warfarin.
    • Naproxen and probenecid may cause increased plasma half-life of naproxen.
    • Naproxen and methotrexate may significantly increase and prolong blood methotrexate concentration, which may be severe or fatal.
  • Interaction with Disease

    Use with caution in patients with GI disease (bleeding or ulcers), cardiovascular disease (CHF, hypertension), dehydration, renal or hepatic impairment, and patients receiving anticoagulants; perform ophthalmologic evaluation for those who develop eye complaints during therapy (blurred vision, diminished vision, changes in color vision, retinal changes); NSAIDs may mask signs/symptoms of infections; photosensitivity reported; elderly are at especially high-risk for adverse effects.
  • Interaction with Food

    Food may decrease the rate but not the extent of oral absorption. Drug may cause GI upset, bleeding, ulceration, perforation; take with food or milk to minimize GI upset.

Ques: What is Naproxen used for?

Ans: This medication used to treat various types of conditions such as abdominal cramps, antipyretic, vomiting, juvenile idiopathic arthritis, and symptoms related to idiopathic or diabetic gastroparesis. It contains domperidone and Naproxen as active ingredients.

Ques: What are the side effects of Naproxen?

Ans: Some of the side effects include drowsiness, headache, depression, itching, the inability of concentration, swelling of eyes and lips, etc.

Ques: Is Naproxen safe during pregnancy?

Ans: Kindly consult with a doctor or specialist for a recommendation on a particular case.

Ques: How long do I need to use Naproxen before I see improvement in my condition?

Ans: This medication is to be taken till the time you see an improvement in your health conditions.

Ques: At what frequency do I need to use Naproxen?

Ans: This medication should be taken in the dosage as prescribed by the doctor.

Ques: What are the instructions for the storage and disposal of Naproxen?

Ans: This medication should be kept in a cool dry place and in its original packaging. Make sure this medication remains unreachable to children and pets.

Ques: Does Naproxen contain sulfa?

Ans: Naproxen doesn't contain any sulfa substance.

Ques: Is Naproxen a controlled substance?

Ans: Yes, it is not a controlled substance, however, it is available only when prescribed by a doctor.

Ques: Is Naproxen addictive?

Ans: Naproxen has not been reported to have any addictive potential.
Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

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Content Details
Written By
PhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child Care
Reviewed By
MBBS, Master in Healthcare Administration, Diploma in Occupational Health
General Physician
Table of Content
About Naproxen
What are the uses of Naproxen
What are the contraindications of Naproxen ?
What are the side effects of Naproxen ?
Key highlights of Naproxen
What are the dosage instructions?
Medicines containing Naproxen
How does this medication work?
What are the interactions of Naproxen ?
FAQs about Naproxen