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Common Specialities
Common Issues
Common Treatments


Prescription vs.OTC: Prescription by Doctor required

Naproxen is a non-steroidal anti-inflammatory drug which works by reducing the hormones causing pain and inflammation in the body. by conditions such as ankylosing spondylitis, arthritis, tendinitis, gout, bursitis or menstrual cramps.On using this medicine some side effects like stomach upset, nausea, vomiting, heartburn, drowsiness, headache may occur. Serious side effects may include easy bruising or bleeding, painful swallowing, ringing in the ears, signs of kidney problems, mood changes, unusual tiredness, swelling of the ankles, feet and hands, unexplained stiff neck, unexplained weight gain and vision changes.

To ensure this medicine is safe for you tell your doctor if you have asthma, blood disorders, nasal polyps, liver disease, heart disease, stroke, high blood pressure or throat, stomach or intestinal problems.

Take this medicine by mouth as instructed by your doctor, usually 2 or 3 times in a day. Remember to not lie down for a minimum of 10 minutes after taking it. To prevent stomach upset, take this drug with milk, food or an antacid. To reduce your risk of side effects, start the medication at the lowest effective dose for a short period of time. Take a higher dosage if needed, after consulting with a doctor.

Information given here is based on the salt and content of the medicine. Effect and uses of medicine may vary from person to person. It is advicable to consult a Orthopedist before using this medicine.

In addition to its intended effect, Naproxen may cause some unwanted effects too. In such cases, you must seek medical attention immediately. This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.

Is It safe with alcohol?

Taking Naproxen with alcohol can increase the risk of stomach bleeding caused by naproxen.

Are there any pregnancy warnings?

Comig 250 tablet may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.

Are there any breast-feeding warnings?

Unknown. Human and animal studies are not available. Please consult your doctor.

Is it safe to drive while on this medicine?

Do not drive, operate machinery.

Does this affect kidney function?

Naproxen should not be given in renal failure.
Caution should be used in patients with severe renal impairment.

Does this affect liver function?

There is no interaction between liver impairment and consuming this drug. So dose alteration is not needed.
Below is the list of medicines, which contains Naproxen as ingredient
Tas Med India Pvt Ltd
Seagull Labs (I) Pvt Ltd
Abbott India Ltd
Macleods Pharmaceuticals Pvt Ltd
Sun Pharmaceutical Industries Ltd
Mission Research Laboratories Pvt Ltd
Lupin Ltd
Molekule India Pvt Ltd
Icon Life Sciences
Arinna Lifescience Pvt Ltd
Arinna Lifescience Pvt Ltd
Zydus Cadila
Icon Life Sciences
Crescent Therapeutics Ltd
RPG Life Sciences Ltd
Tas Med India Pvt Ltd
Crescent Therapeutics Ltd
Intas Pharmaceuticals Ltd
RPG Life Sciences Ltd
Macleods Pharmaceuticals Pvt Ltd
Intas Pharmaceuticals Ltd
Naproxen are NSAIDs (Non Steroidal Anti Inflammatory Drug) that inhibit prostaglandin synthesis by non selectively impeding the COX -1 And COX -2 enzymes. This helps in alleviating inflammation, as prostaglandin is a regulator for inflammation in muscles.

Ques: What is Naproxen used for?

Ans: Naproxen is a medication used to treat various types of conditions such as abdominal cramps, antipyretic, vomiting, juvenile idiopathic arthritis and symptoms related to idiopathic or diabetic gastroparesis. this medication contains domperidone and naproxen as active ingredients. do not chew or break this medicine, it has to be swallowed as whole and can be taken with or without food at a fixed time.

Ques: What are the side effects of Naproxen?


Naproxen has several side effects that can appear because of it’s ingredients which are domperidone and naproxen.

Some of the side effects are mentioned below;

  1. drowsiness
  2. headache
  3. depression
  4. itching
  5. inability of concentration
  6. swelling of eyes and lips

Ques: How does the medicine work?


Naproxen consist domperidone and naproxen in which domperidone helps in getting rid from undiagestest food and reducing the risk of an upset stomach, heartburn and throwing up, while naproxen works reducing hormones that cause pain, swelling and fever. this medicine can be used to treat the following;

fractured - ankle, breastbone, collarbone, elbow, eye socket, finger, hand, hip, nose, toe, wrist, rib, foot, jaw, etc.

  1. gout
  2. leg pain
  3. fever
  4. joint pain
  5. headache
  6. back pain
  7. chikungunya
  8. rheumatoid arthritis
  9. osteoarthritis
  10. rib pain
  11. indigestion

Ques: Is Naproxen safe during pregnancy?

Ans: Kindly consult with a doctor or specialist for a recommendation on a particular case.
What are you using Naproxen for?
muscle pain
rheumatoid arthritis
ankylosing spondylitis
How much was the improvement?
How long did it take before seeing improvement?
Within 2 hours
More than 2 days
Within 6 hours
Within a day
Within 2 days
How frequently did you take this medicine?
Once a day
Not taking on daily level
Twice a day
Four times A Day
Thrice a day
How did you take this medicine?
With Food
With or without food
Empty stomach
What were the side effects of this medicine?
Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

Popular Questions & Answers

Whenever I go for running, there is an acute pain in my knees. Is it normal? Or amounts to some kind of deficiency?

MBBS, M. S. Orthopaedics, Fellowship in Arthroscopy and sports medicine, DNB (Orthopaedics)
Orthopedist, Jaipur
Whenever I go for running, there is an acute pain in my knees. Is it normal? Or amounts to some kind of deficiency?
Hi. Acute pain in knees while running is not normal. There may be a problem in your knee cap or meniscus or any cartilage in knee joint. This has to be clinically evaluated and appropriately treated. I would also advise you to stop running as it might make the matter more worse until you get your problem evaluated.

My age is 22 year. 4-5 month ago I have erosive gastritis .I am feeling pressure and pain in mid upper chest. I went to Dr. And take medicine's 90-100 days properly and feel much better. After stopping medicine's. Again I feel pressure and pain in chest all the day. Chest is paining during deep breathing, stretching and pushing the chest. My digestion is good now. So why I am still feeling pressure and pain in my chest. Sir please tell me permanent solution.

MBBS, Dip.Cardiology, Fellowship in Clinical Cardiology(FICC), Fellowship in Echocardiology
Cardiologist, Ghaziabad
My age is 22 year.
4-5 month ago I have erosive gastritis .I am feeling pressure and pain in mid upper chest. I went ...
What you are having is Gastroesophageal reflux disease Gastroesophageal reflux disease (GERD) is a condition in which the stomach contents leak backwards from the stomach into the esophagus (the tube from the mouth to the stomach). This can irritate the esophagus and cause heartburn and other symptoms. Causes When you eat, food passes from the throat to the stomach through the esophagus. A ring of muscle fibers in the lower esophagus prevents swallowed food from moving back up. These muscle fibers are called the lower esophageal sphincter (LES). When this ring of muscle does not close all the way, stomach contents can leak back into the esophagus. This is called reflux or gastroesophageal reflux. Reflux may cause symptoms. Harsh stomach acids can also damage the lining of the esophagus. The risk factors for reflux include: Use of alcohol (possibly) Hiatal hernia (a condition in which part of the stomach moves above the diaphragm, which is the muscle that separates the chest and abdominal cavities) Obesity Pregnancy Scleroderma Smoking Symptoms can also be caused by certain medicines Common symptoms of GERD include: Feeling that food is stuck behind the breastbone Heartburn or a burning pain in the chest Nausea after eating Less common symptoms are: Bringing food back up (regurgitation) Cough or wheezing Difficulty swallowing Hiccups Hoarseness or change in voice Sore throat Symptoms may get worse when you bend over or lie down, or after you eat. Symptoms may also be worse at night. If you are overweight or obese, in many cases, losing weight can help. Avoid drugs such as aspirin, ibuprofen, or naproxen. Take acetaminophen to relieve pain. Take all of your medicines with plenty of water. When your doctor gives you a new medicine, ask whether it will make your heartburn worse. You may use over-the-counter antacids after meals and at bedtime, although the relief may not last very long. Common side effects of antacids include diarrhea or constipation. Other over-the-counter and prescription drugs can treat GERD. They work more slowly than antacids, but give you longer relief.
1 person found this helpful

Hello doctor for past two weeks I have a sprain in my left neck and shoulders. Is it because of muscle weakness. How can I get through it please suggest.

General Physician, Fatehabad
Hello doctor for past two weeks I have a sprain in my left neck and shoulders. Is it because of muscle weakness. How ...
Hi lybrate-user, While neck and shoulder pain can occur due to traumatic injuries or bone degeneration, muscle strain represents the main cause. 1. Relieve Stress: Getting rid of the cause of shoulder and neck pain marks the first step toward healing. Home treatment should begin with rest, a break in an exercise routine and an attempt to address the source of upper-body pain. 2. Releive Pain: Home treatment to reduce inflammation eases pain symptoms. For short-term shoulder and neck pain relief, doctors recommends nonsteroidal anti-inflammatory drugs, such as naproxen and ibuprofen, along with acetaminophen. These medications can be used periodically for chronic pain, but may result in long-term side effects. They are over the counter drugs available without prescription. 3. Hot Cold Compression - You can also consider moist heat and cold compresses safe for either short- or long-term conditions of neck and shoulder pain. Heat applications can come from a hot shower, a hot-water bottle or a reusable heated gel pack. Cold packs can be made with ice, a bag of frozen peas or a chilled gel pack. Patients should alternate 20 minutes of heat with 20 minutes of cold, ending with cold therapy to discourage inflammation. 4. Restore Function: Restore Function Immobilizing the neck for long periods of time will make painful muscular conditions worse. Home treatment to restore muscle strength and flexibility should begin as soon as the initial acute neck and shoulder pain and inflammation have passed, usually within 48 hours of onset. Hope this helps. Good luck.

Sir/madam, I running continued since 1st Aug 17, Now after running 2 Km my legs/knee started pain. What's the reason & what should I do.

MPT, Mphill
Physiotherapist, Delhi
Sir/madam, I running continued since 1st Aug 17, Now after running 2 Km my legs/knee started pain. What's the reason ...
Dear lybrate-user you may shin pain, whenever you do over training or beyond your limits then there is micro fractures at the front of your lower leg. Stop running and use ICE massage at least 4-5 times in a day, wrap crape Bandage around painful area.

Please suggest medicine to my mom for knee sprain and swelling after sudden fall yesterday. Difficult to walk. Thanks dr.

General Physician, Mumbai
Please suggest medicine to my mom for knee sprain and swelling after sudden fall yesterday. Difficult to walk.
Dear Lybrateuser, - Give rest to the limb, walk with support - apply a ice pack for 5-10 min 2-3 times a day - give a pain relief tablet like. Naproxen, 1 tablet twice a day after meals till pain subsides -apply a pain relief gel three times a day - wear a knee cap - also an x- ray be dine if pain & swelling do not improve after a couple of days.
1 person found this helpful

Popular Health Tips

Vaginal Bleeding Between Periods - 5 Ways To Prevent It!

MBBS, MS - Obstetrics and Gynaecology
Gynaecologist, Gurgaon
Vaginal Bleeding Between Periods - 5 Ways To Prevent It!

Many women experience unusual vaginal bleeding between periods at some point in their lives. It is also known as metrorrhagia. Vaginal bleeding is thought to be abnormal in the following cases:
1. When your menstrual period is not expected
2. When your menstrual flow is lighter or heavier than normal
3. At unexpected stages in life. For example, when you are pregnant or after you have attained menopause.

Bleeding during periods is not a normal condition. Usually, the duration of the cycle is about 21 – 35 days. Abnormal vaginal bleeding has numerous conceivable causes. Independently, it doesn't show a genuine condition.

  1. Mid-cycle bleeding can be caused due to ovulation.
  2. Two hormones that regulate the menstrual cycle are progesterone or oestrogen. A condition of hormonal imbalance which is known as Polycystic ovary syndrome (PCOs) causes interference with normal ovulation. This results in problems in thyroid glands as well as causes dysfunctional ovaries.
  3. Medications such as birth control pills are capable of causing abnormal bleeding, especially with the irregular intake of such medications.
  4. Infections or inflammation caused in the pelvic regions such as uterus, vagina, cervix, ovaries or fallopian tubes are capable of causing abnormal bleeding. STIs (Sexually Transmitted Diseases) and PIDs (Pelvic inflammatory disease) are often the cause of such a condition.
  5. Although Cancer is not one of the primary causes, cancer in organs such as the uterus, vagina, cervix and ovaries are capable of causing abnormal bleeding during periods.

How it can prevented

  1. Maintaining a healthy diet. Women who are either underweight or overweight tend to have more problems with abnormal bleeding
  2. Relaxation practices should be followed so that stress is reduced. Stress can cause abnormal bleeding.
  3. Non-steroidal anti-inflammatory drugs (NSAID) should be consumed to reduce menstrual bleeding. Examples are ibuprofen or naproxen.
  4. In case of consumption, birth control pills should be taken as per the prescription only and regularly at the same time.
  5. Hormone therapy (using external hormones in a medical treatment) can be used in order to regulate menstrual cycles, stabilize the endometrium which is the lining of the uterus as well as to rectify hormonal imbalances. In case you have a concern or query you can always consult an expert & get answers to your questions!
3769 people found this helpful

Chemical Burns - Do's and Don'ts of It!

MD - Dermatology , Fellowship in Hair Transplant
Dermatologist, Nashik
Chemical Burns - Do's and Don'ts of It!

A chemical burn can occur owing to a number of substances, for instance, if the skin comes in contact with strong acids, bases, irritants, gasoline, paint thinner and drain cleaners then it react with your skin. Chemical burns are also termed as caustic burns. The symptoms usually depend on the intensity of a burn, which include redness, irritation, numbness, pain, the skin turning black and dead or even vision loss, if the chemicals come in contact with the eyes.

What are the Do’s and Don’ts?

  1. Do away with those chemicals, which have caused the burn or wipe off the dry chemicals. It is safe to use towels or put on gloves for this work.

  2. Remove jewelry or any contaminated clothing to avoid further burning and inflammation of the skin.

  3. Rinse off the affected area immediately with cold water.

  4. Loosely wrap the area with sterile gauze or a bandage.

  5. If required, you can even opt for pain relievers such as naproxen sodium, ibuprofen or acetaminophen.

  6. Consider taking a tetanus injection, but at the same time, ensure that your booster is up-to-date.

  7. Refrain from applying an antibiotic ointment over the burnt area or neutralizing it with an alkali or acid. This may aggravate the burn.

When should you seek an emergency care?

  1. When the person exhibits sign of shock such as shallow breathing, pale complexion or is experiencing bouts of fainting.

  2. When the chemical burn pierces through the upper layer of the skin, occupying an area of above 3 inches in diameter.

  3. When the chemical burn has spread to the buttocks, groin, face, feet, hands, eyes or even the limb.

In case you have a concern or query you can always consult an expert & get answers to your questions!

4384 people found this helpful

6 Ways To Deal With Pinched Nerve!

Pain Management Specialist, Kolkata
6 Ways To Deal With Pinched Nerve!

Our body is composed of many elements that carry out emotional and physical functions that are usually in sync with one another. It is important for these organs and other elements to be in sync for good health. All nerves are connected to the brain and are responsible for sending important signals throughout your body. Therefore, even one pressed nerve may send you warning signals such as pain to the body. It is advisable not to overlook these signals. Damage from a pressed nerve might be minor or extreme. It might bring about persistent and chronic issues. Therefore, the sooner you get a treatment for nerve compression, the more relieving experience you will have. In a few cases, you cannot reverse the damage caused by a pressed nerve. However, treatment does relieve you from the pain in most cases.

Nerves are the most vulnerable at spots in your body where they go through narrow spaces and have very less tissue to protect them. These are the places they are more likely to get pinched. A number of the causes may include:

  1. If the nerve is pressed between tissues, for example, your tendon, ligament or bone.
  2. Nerve compression in your neck or arm may likewise bring pain in zones, for example, your elbow, hand, wrist or fingers.
  3. Aggravation or weight on a nerve root leaving the spine may bring about neck or low back pain.
  4. In case a disc tears, it is known as a herniated circle that can put weight on a spinal nerve.

Some of the common symptoms of pinched nerves are:

  1. Pain in the region of pressure, for example, the neck or low back
  2. Transmitting pain, for example, sciatica or radicular pain
  3. Numbness
  4. Tingling
  5. Blazing sensation
  6. Weakness

To what extent you are affected depends on individual to individual. Treatment fluctuates, based upon the seriousness and reason for the pinched nerve. You may find that you benefit from just resting the affected area and by maintaining distance from any exercises that may cause you harm. If side effects endure or torment is serious, it is best to consult a specialist. You may require one or more types of treatment to contract swollen tissue around the nerve.

Treatment may include:

  1. NSAIDs - Non-steroidal inflammation mitigating drugs (NSAIDs, for example, headache medicine, ibuprofen, or naproxen) may diminish swelling & helps in certain situation' but it do not work in most of the time and must be avoided. 
  2. Oral corticosteroids - These are utilized to lessen swelling and agony, used in certain specific situations. 
  3. Opiates - These are utilized for brief periods to lessen extreme pain. 
  4. Co-analgesics - These are the main medicines for nerve pain. Carbamazepine, Pregabalin, Duloxetine etc medicines are best medicines for these situations. 
  5. Interventional Pain Procedures - They are the most cost effective and non invasive methods for pain relief as recommended by the WHO. Your pain will be taken care of by the interventional pain physician or the pain specialist. 
  6. Surgery - Surgery might be required for more serious issues that do not react to different sorts of treatment.

In case you have a concern or query you can always consult an expert & get answers to your questions!

8335 people found this helpful

Peripheral Neuropathy - Ways To Control It!

MBBS, DNB, Fellowship In Neurosurgery
Neurosurgeon, Kolkata
Peripheral Neuropathy - Ways To Control It!

The sensation of pain and numbness are quite common in patients suffering from high blood sugar. If you are suffering from nerve damage from high blood sugar, chances are you have diabetic peripheral neuropathy. The discomfort can affect your mood and overall quality of life. But with some easy to follow steps can help you keep peripheral neuropathy under control.

  1. Keep your blood sugar levels under control: Your first task is to manage your blood sugar levels under control and with the passage of time it will damage the peripheral nerves and pave the way for diabetic neuropathy. If you can keep your blood sugar levels within a healthy range, you will be able to reduce the risk of nerve damage by about 60 percent. You should talk to your doctor first since a rapid drop in the blood sugar levels can prove to be even worse.
  2. Get the right level of Vitamin D: Your skin functions by producing Vitamin D in response to sunlight and it is immensely helpful in shielding against nerve pain. It has been found people who have lower levels of this nutrient are more likely to suffer from more pain. In case it is hard to get the recommended daily intake from food only, you will have to take supplement pills.
  3. Keep away from smoking: We all know that smoking causes the blood vessels to constrict which hampers circulation. If you don’t quit smoking, your peripheral nerves may not be able to nutrient-rich blood which would make pain worse.
  4. Take a warm bath: Warm water is not just relaxing, it can also improve circulation all through the body. It can provide instant relief. But it is worthy of mention here that since diabetic neuropathy leads to loss of sensation, you should ensure that the water isn’t too hot before you jump in.
  5. Seek resort to over the counter medications: There is a host of painkillers available for easing mild to moderate ache stemming from diabetic neuropathy. These include ibuprofen, aspirin, naproxen and acetaminophen. But before taking any of these pills, you should consult with an expert who can choose the right medicine for you.
  6. Get up and move: Exercise can combat pain in a variety of ways. It helps in keeping blood sugar levels under control which, in turn, can hinder nerve damage. Workout increases blood flow to the extremities while also uplifting your mood. It will help you get rid of stress so that you can better deal with the symptoms of peripheral neuropathy. In a study conducted by the University of Kansas, it was found that people who exercise regularly didn’t face any trouble in doing daily activities.
  7. Consider carpal tunnel surgeryWhen the patient is suffering from localized peripheral nerve compression that affects the hands, carpal tunnel surgery can be considered as a last resort to achieve pain relief, reduced incidence of ulceration, increased range of movement and balance, preservation of limbs and improved quality of life.

With these few tips, you will be able to manage the peripheral neuropathy better. In case you have a concern or query you can always consult an expert & get answers to your questions!

3351 people found this helpful

Runner's Knee - How To Get Relief?

MS - Orthopaedics, MBBS
Orthopedist, Chennai
Runner's Knee - How To Get Relief?

Runner's knee is not a particularly dangerous problem. It is an expansive term that refers to the pain you feel in case you have one of the few knee issues. For instance, chondromalacia patella, a condition due to softening of the cartilage under the kneecap can lead to runner's knee side effects.

Runner's knee can happen for a few reasons:

  1. Overuse of the knee in case you are performing highly stretchable exercises
  2. An immediate hit to the knee as from a fall or a blow
  3. Your bones are not lined up or aligned properly (this is called malalignment)
  4. If any of the bones from your hips to your lower legs are out of their right positions, including the kneecap itself, excessive amount of weight can be felt on specific spots in the joint. At that point, your kneecap will not move easily, which can bring about pain.
  5. Problems with your feet like hypermobile feet (when the joints in and around the feet move more than they should)
  6. Powerless or unequal thigh muscles. The muscles in the front of your thigh keep your kneecap in its place when you stretch or bend the joint. If they are tight, your kneecap may shift.

Symptoms of Runner's Knee:

The main symptom you will notice is pain. It can happen:

  • In front, behind, or around your kneecap
  • When you bend your knee, such as when you walk, squat, kneel, run, or even get up from a chair
  • When you walk downstairs or downhill

You might also notice swelling around your knee or a popping or grinding feeling inside the joint.

For the vast majority, runner's knee shows signs of improvement with time. However, certain treatments or remedies for pain elevation are as follows:

  1. Rest your knee. Try to avoid exercises that aggravate the pain, for example, running, lunging, squatting, or sitting or standing for long periods of time.
  2. Ice your knee to relieve the pain and swelling. Do it for 20 to 30 minutes each three to four hours for three days, or until the pain is gone.
  3. Wrap your knee. Use a flexible wrap, brace, or sleeves to give it additional support.
  4. Keep your leg raised on a cushion when you are sitting or resting.
  5. Take non-steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen or naproxen. These medications help in getting rid of the irritation and help in reducing the pain and swelling. However, they can have reactions such as a risk of bleeding and ulcers.
  6. Do stretching exercises, especially for your quadriceps muscles. Your specialist can prescribe a physiotherapist to show you what to do.
  7. Try arch or knee supports for your shoes. They may help with the position of your feet. You can get them at the store or get them custom-made.
  8. In case that you attempt these procedures and your knee still hurts, enquire as to whether you have to see a surgeon.
  9. Your specialist additionally may suggest that you get injections of a corticosteroid to help with the pain. However, these are not replacements for rest or exercises.
  10. Although it is uncommon, extreme instances of runner's knee may require surgery. An orthopedic specialist can replace or remove the affected ligament and, in extraordinary cases, adjust the position of the kneecap.

An Orthopaedic specialist can help you sort out the problem. In case you have a concern or query you can always consult an expert & get answers to your questions!

2666 people found this helpful
Table of Content
About Naproxen
When is Naproxen prescribed?
What are the side effects of Naproxen ?
Key highlights of Naproxen
Medicines containing Naproxen
How does medicine works?
Naproxen Frequently Asked Questions (FAQs):