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Megapime 500 MG Injection

Manufacturer: Alkem Laboratories Ltd
Medicine composition: Cefipime
Prescription vs.OTC: Prescription by Doctor required
Last Updated: May 20, 2019

Megapime 500 MG Injection is useful in managing bacterial infections such as pneumonia and skin infections, kidney as well as urinary tract infections. It is also used in combination with other medications for treating infections in the abdominal area. The medication belongs to the class of cephalosporin antibiotics and treats infections caused due to the low white blood cell count. Megapime 500 MG Injection kills the bacteria and inhibits the infection from spreading in the body. The injection is administered into a vein or a muscle, as instructed by your doctor. It is also available in powder form that can be mixed with liquid and also in a pre-mixed liquid form.

The dosage of Megapime 500 MG Injection varies from one patient to another and depends on your overall health condition. The infection you are suffering from and your body’s reaction to the first dose are secondary factors that should be considered for determining the dose and duration. In case you are taking this medication at home, ensure that you have complete knowledge regarding the preparation and usage. Continue using it till the time you have been prescribed by the doctor, even if you feel that you are getting better. Stopping it abruptly in the middle of the course can result in the returning of the infection. Also, do not take two doses to make up if you have missed a dose previously.

Megapime 500 MG Injection causes side effects such as headache, diarrhea and pain, redness or swelling in the area where it has been injected. You can wait for the symptoms to go away or consult your doctor if it bothers you. Some of the serious side effects are:

In case you are pregnant or planning to be, or a breastfeeding mother, consult your doctor before taking Megapime 500 MG Injection.

Pyelonephriits

Skin and Soft tissue infections

Intra-abdominal Infection

In addition to its intended effect, Megapime 500 MG Injection may cause some unwanted effects too. In such cases, you must seek medical attention immediately. This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.

Abdominal pain

Moderate Less Common

Bleeding gums

Moderate Less Common

Convulsions

Moderate Less Common

fever

Moderate Less Common

headache

Moderate Less Common

Yellowing of skin and eyes

Moderate Less Common

Swelling of foot

Moderate Less Common

diarrhea

Moderate Less Common

Redness of skin

Moderate Less Common

Pain at the injection site

Moderate Less Common

Itching of vagina or genital area

Moderate Less Common

Sour mouth

Moderate Less Common

How long is the duration of effect?

The effect of this medication lasts for a duration of about 6 hours.

What is the onset of action?

The top effect of this injection is usually observed in 1 to 2 hours of an intramuscular administration.

Are there any pregnancy warnings?

This medication should not be used by pregnant women. Consult a doctor before using it.

Is it habit forming?

No habit forming tendency has been reported for this injection.

Are there any breast-feeding warnings?

This injection is probably safe to use during breastfeeding. It is still recommended to consult a doctor before taking this medication.
Below is the list of medicines, which have the same composition, strength and form as Megapime 500 MG Injection , and hence can be used as its substitute.
Macleods Pharmaceuticals Pvt.Ltd
Orchid Chemicals & Pharmaceuticals Ltd
Unichem Laboratories Ltd

Missed Dose instructions

The missed dose should be taken as soon possible. It is advisable to skip the missed dose if it's already time for your next scheduled dose.

Overdose instructions

Seek emergency medical treatment or contact the doctor in case of overdose.
Megapime 500 MG Injection belongs to the fourth generation cephalosporins. It works as a bactericidal by inhibiting the bacterial cell wall synthesis by binding to the penicillin-binding proteins which would inhibit the growth and multiplication of bacteria.
Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

Interaction with Disease

Impaired kidney function

Moderate
Megapime 500 MG Injection should not be used in patients who suffer from impaired kidney function or any other kidney disease.

Colitis

Moderate
Avoid if you are suffering from any gastrointestinal diseases such as colitis. Drink plenty amount of water to prevent dehydration.

Impaired Liver function

Moderate
Do not use it if you suffer from liver disease or a family history of liver disease as it can lead to undesired effect.

Seizure disorders

Moderate
Do not use it if you have any seizure disorder or a family history of seizures. A suitable and safe alternative should be used in such a case.

Interaction with Alcohol

Alcohol

Moderate
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Interaction with Lab Test

Lab

Moderate
Information not available.

Interaction with Food

Food

Moderate
Information not available.

Interaction with Medicine

Amikacin

Moderate
You may experience nausea or vomiting, increased or decreased urination, sudden weight gain, and fluid retention if these medicines are used together. This interaction is more likely to occur if you have a kidney disease. Regular kidney function tests are to be performed and appropriate dose adjustments or replacement of the medicine should be made under the doctor's supervision.

Ethinyl Estradiol

Moderate
The desired effect of contraceptive pills will not be achieved if these medicines are taken together. Appropriate dose adjustments or replacement of the medicine should be made under the doctor's supervision.

Cholera Vaccine

Moderate
You should avoid taking Cholera vaccine for atleast 14 days after taking Megapime 500 MG Injection. Usage of other antibiotics and vaccines should be reported to the doctor.

Furosemide

Moderate
You may experience nausea or vomiting, increased or decreased urination, sudden weight gain, and fluid retention if these medicines are used together. This interaction is more likely to occur in the elderly population with preexisting kidney disease. Regular kidney function tests are to be performed and appropriate dose adjustments or replacement of the medicine should be made under the doctor's supervision.
Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

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Table of Content
About Megapime 500 MG Injection
What are the uses of Megapime 500 MG Injection
What are the contraindications of Megapime 500 MG Injection ?
What are the side effects of Megapime 500 MG Injection ?
Key highlights of Megapime 500 MG Injection
What are the substitutes for Megapime 500 MG Injection ?
What are the dosage instructions?
How does medicine works?
What are the interactions of Megapime 500 MG Injection ?