Hydroxyprogesterone

Hydroxyprogesterone is a synthetic prescription medication given to pregnant women. It prevents the chances of an early delivery. This injection is given to women after the first trimester. This is a hormone medication that belongs to a category of drugs known as progestin.

This medicine is also used for the treatment of amenorrhea, abnormal uterine bleeding, endometriosis and uterine carcinoma. It needs to be administered into the muscles by trained hands only.

Do not use this injection If you have or are:

• Allergic to any medicine, foods, substances or any of the ingredients contained within this injection.
• Taking any prescriptive or non-prescriptive drugs, herbal, vitamins or dietary supplements.
• Diabetes or high blood sugar.
• Heart, liver or kidney problems.
• Vaginal bleeding.
• Breastfeeding a baby.
• History of -
  • asthma or depression.
  • Epilepsy or any other kind of seizures.
  • Hormone-sensitive cancers.

The common side effects associated with Hydroxyprogesterone are swelling, itching, nausea, tiredness, dizziness, fever, skin eruptions and pain at the site of injection. If any severe reactions arise seek the help of your health care provider as soon as possible.

Probable allergic reacions are redness, difficulty in breathing, severe swelling of the face, lips, mouth, throat, hands, ankles or feet, signs of depression and coughing up blood.

Hydroxyprogesterone must be used with caution in patients with asthma, seizure disorders, migraine, cardiac or renal impairment, history of mental depression. Use of any progestin during the first 4 months of pregnancy is not recommended. And patients must be observed closely for signs and symptoms of thrombotic disorders.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Laser Gynae before using this medicine.

• Premature Labor

• Menstrual Abnormalities

• Amenorrhea

• Abnormal Uterine Bleeding

• Endometriosis

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Laser Gynae before using this medicine.

• Allergy

• Abnormal Vaginal Bleeding

• Liver Disease

• Breast / Uterine Cancer

• Thrombophlebitis

• Cerebral Hemorrhage

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Laser Gynae before using this medicine.

• Edema (Swelling)

• Bleeding

• Menstrual Changes

• Amenorrhea

• Anorexia

• Weakness

• Insomnia

• Fever

• Pruritus

• Weight Gain

• Weight Loss

• Breast Tenderness

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Laser Gynae before using this medicine.

• How long is the duration of effect?

  The time duration for which this medicine remains effective in the body is 1-2 weeks.

• What is the onset of action?

  The time taken for this medicine to show it's effect is subject to vary from one person to another. It also varies based on the intended use and levels of other sex hormones in the body.

• Are there any pregnancy warnings?

  This medicine is not recommended for use by pregnant women unless absolutely necessary and the benefits outweigh the risks associated with use. Consult your doctor before using this medicine.

• Is it habit forming?

  No habit forming tendencies were reported.

• Are there any breast-feeding warnings?

  This medicine is not recommended for use by breastfeeding women unless necessary. Consult your doctor before using this medicine.

• Is It safe with alcohol?

  The effect after the concomitant consumption of alcohol and this medicine is unknown. Kindly consult your doctor.

• Is it safe to drive while on this medicine?

  This medicine is usually found to be safe.

• Does this affect kidney function?

  Limited information is available regarding its use in patient with kidney disease. Kindly consult your doctor before taking this medicine.

• Does this affect liver function?

  Caution must be taken in patients with hepatic impairment. Adjustment of dose might be needed. Kindly consult your doctor before taking this medicine.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Laser Gynae before using this medicine.

• Missed Dose instructions

  Contact your doctor for further instructions if you miss a scheduled dose of this medicine.

• Are there any overdose instructions?

  Contact a doctor if an overdose with this medicine is suspected.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Laser Gynae before using this medicine.

• India

• United States

• Japan

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Laser Gynae before using this medicine.

Below is the list of medicines, which contains Hydroxyprogesterone as ingredient

• Hyprogest 500 MG Injection

  Colinz Laboratories Ltd

• Caprogen 500 MG Injection

  Macmillon Pharmaceuticals

• Uniprogestin 250 MG Injection

  Unichem Laboratories Ltd

• Anin 500 MG Injection

  Indswift Laboratories Ltd

• Alese 500 MG Injection

  Zee Laboratories

• Hyprogest 200 MG Capsule

  Colinz Laboratories Ltd

• Proluton 250 MG Injection

  Zydus Cadila

• Proluton Depot 500Mg/2Ml Injection

  Zydus Cadila

• Fetugest 500 MG Injection

  Obsurge Biotech Ltd

• Gestimax 500 MG Injection

  Unimarck Healthcare Ltd

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Laser Gynae before using this medicine.

This medication works by stimulating the actions of the luteal phase and causes changes in the uterus and vagina. It also affects the uterus and prevents contractions caused due to oxytocin.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Laser Gynae before using this medicine.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

test

• Interaction with Alcohol

  Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

• Interaction with Lab Test

  Thyroid function test

  Report the use of hydroxyprogesterone to the doctor before undergoing a thyroid function test. This medicine can interfere with the test and give a false positive result.

• Interaction with Medicine

  Carbamazepine

  Report the use of either of the medicine to the doctor. You may require a dose adjustment or more frequent monitoring to ensure the safe use of these medicines together. Alternate means of birth control should be discussed with your doctor while using carbamazepine. Do not stop the use of any medication without consulting your doctor.

  Ketoconazole

  Report the use of either of the medicines to the doctor. You may need a dose adjustment and frequent monitoring to safely use these medicines together. Report any instances of nausea, vomiting, or vaginal bleeding to the doctor on priority while using these medicines.

  Warfarin

  Use of this medicine can reduce the blood level and effect of warfarin. You may a need a dose adjustment and more frequent clinical monitoring to safely use these medicines together

  Cyclosporine

  Use of this medicine may reduce or diminish the effect of cyclosporine. You may need a dose adjustment and more frequent monitoring to safely use these medicines. Do not stop the use of any medicine without consulting your doctor.

  Insulin

  Report the use of insulin or any other anti-diabetic medicine to the doctor before receiving hydroxyprogesterone. You may need an adjusted dose of the antidiabetic medicine and more frequent monitoring of blood glucose level in such cases.

  Paracetamol

  Use of this medicine may reduce or diminish the effect of paracetamol. You may need a dose adjustment and more frequent monitoring to safely use these medicines. Do not stop the use of any medicine without consulting your doctor.

• Interaction with Disease

  Breast Cancer

  Use of this medicine is not recommended for patients having an active case of breast cancer or are suspected of having it. Report all such instance including occurrence in the past to the doctor so that an informed decision can be taken in regards to the future treatment plan.

  Liver Disease

  Use of this medicine is not recommended if the patient has a liver disease or the normal liver function is impaired.

  Thromboembolism

  Use of this medicine is not recommended in patients having a clotting disorder in which the formed clot moves from one place and lodges in another place.

  Depression

  This medicine should be used with caution in patients having episodes of depression or having a history of depression especially when estrogen is also administered in combination. The drug should be discontinued if the depression recurs and is serious.

  Retinal Thrombosis

  Use of this medicine can sometimes cause a loss of vision by blocking the flow of blood from the retina to the heart. Hence caution should be exercised while using it and any abnormality in vision should be reported to the doctor.

• Interaction with Food

  Information not available.

• Ques : What is Hydroxyprogesterone? What are its uses?

  Ans : Hydroxyprogesterone is progesterone (a type of female sex hormone). It helps to lower the risk for a woman to have a premature baby (early birth). It is generally taken to lower the risk of a premature baby for a second time.

• Ques : How should I use Hydroxyprogesterone?

  Ans : Hydroxyprogesterone is given as an injection, by a doctor or trained nurse.

• Ques : In what amount of dosage should I consume Hydroxyprogesterone?

  Ans : Consult your doctor for the dosage. It depends on the medical condition of the patient.

• Ques : What if the dose is skipped from the prescribed schedule of Hydroxyprogesterone?

  Ans : You should make sure not to miss any dose. Nevertheless, if it is missed, consult the doctor as soon as possible.

• Ques : Are there any side effects of Hydroxyprogesterone?

  Ans : Some of the common side effects could be Nausea, itching, diarrhea, weight gain, weight loss, insomnia etc. If any of these are seen, one must consult a doctor.

• Ques : Is Hydroxyprogesterone safe for pregnant women?

  Ans : Hydroxyprogesterone is not recommended for use by pregnant women unless absolutely necessary and the benefits outweigh the risks associated with use. You should consult with your doctor before taking any.

• Ques : Can I get addicted to Hydroxyprogesterone?

  Ans : No such case of addiction or habit forming has been seen till now.

• Ques : Is there any risk involved in consuming Hydroxyprogesterone while I have to drive?

  Ans : This medicine is safe and no risk has been detected till now.

• Ques : I breastfeed my baby. Is Hydroxyprogesterone safe for me?

  Ans : You should consult your doctor before.

• Ques : Can I take Hydroxyprogesterone if I consume alcohol?

  Ans : The reaction with the alcohol is unknown yet. You must consult your doctor.

• Hydroxyprogesterone-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 7 June 2022].Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/hydroxyprogesterone

• Hydroxyprogesterone-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 7 June 2022].Available from:

  https://go.drugbank.com/drugs/DB14570

• HYDROXYPROGESTERONE injection,solution-DailyMed [Internet].dailymed.nlm.nih.gov 2022 [Cited 7 June 2022].Available from:

  https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=HYDROXYPROGESTERONE