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Overview

Harmless Plus 25 MG Syrup

Harmless Plus 25 MG Syrup

Manufacturer: Hi Tec Pharmaceuticals Pvt Ltd
Medicine composition: Colistin
Prescription vs.OTC: Prescription by Doctor required

Harmless Plus 25 MG Syrup is an antibiotic which treats bacterial infections by stopping the growth of bacteria. It is a very effective medicine to treat infections of the stomach and the intestine caused by sensitive gram-negative bacteria. It is also used for performing bowel sterilisation before a surgery.

During your treatment with this medicine, you may experience a few side effects like stomach upset and itching. Serious side effects may include numbness of the arms and legs, confusion, difficulty walking, psychosis, unsteadiness, unexplained fever, seizures, troubled breathing, muscle weakness, dizziness, slurred speech and signs of kidney problems.

You should not take this medicine if you have previously experienced allergies towards any of the ingredients in it or if you suffer from myasthenia gravis (a rare condition where muscle tire very fast), brain toxicity, impaired kidney function or colitis. This medicine should not be used during a pregnancy unless absolutely necessary. Women who are breastfeeding should use it with caution. Medicines like tacrolimus, vancomycin, ethanol estradiol, streptomycin or live cholera vaccine may interfere with the action of Harmless Plus 25 MG Syrup so make sure your doctor knows if you are taking any other medicines.

Harmless Plus 25 MG Syrup is administered into the body by injecting it into a vein or a muscle as directed by your doctor. For severe gram-ve bacterial infections the usual dosage is 2.5-5 mg/kg/day in 2-4 divided doses. Maximum dose prescribed is 5 mg/kg/day. Your prescription depends on your medical condition and response to treatment. It is recommended to keep taking this medicine for the full prescribed duration. Contact your doctor if you see no improvement in your condition.

Bowel sterilization
This medicine is used for bowel emptying before certain surgical procedures are performed.
Gastrointestinal infections
This medicine is used for the treatment of infections of the stomach and intestine. It is particularly effective against gram negative bacteria.
Allergy
This medicine is not recommended for use if you have a known history of allergy to colistin or any other medicine belonging to polymyxin antibiotic group.
Myasthenia Gravis
This medicine is not recommended for use in patients suffering from a rare condition where muscle tire very fast.
In addition to its intended effect, Harmless Plus 25 MG Syrup may cause some unwanted effects too. In such cases, you must seek medical attention immediately. This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.
Burning or tingling sensation of hands and feet Moderate Less Common
Visual disturbances Moderate Less Common
Stomach discomfort and cramps Moderate Rare
Nausea or Vomiting Minor Common
Weakness of arms, hands, legs or feet Moderate Common
Severe difficulty in breathing Major Less Common
Confusion Major Rare
Blood in urine and stools Major Rare
Skin irritation Minor Less Common
How long is the duration of effect?
The time duration for which this medicine remains effective in the body is not clinically established.
What is the onset of action?
The time taken for this medicine to show its effect is subject to variations and is not clinically established.
Are there any pregnancy warnings?
This medicine should not be used during a pregnancy unless absolutely necessary. Consult your doctor and discuss the potential benefits and risks associated with use.
Is it habit forming?
No habit forming tendencies were reported.
Are there any breast-feeding warnings?
This medicine should be used with caution by women who are breastfeeding. Consult your doctor and discuss the potential benefits and risks associated with use.
Below is the list of medicines, which have the same composition, strength and form as Harmless Plus 25 MG Syrup, and hence can be used as its substitute.
Missed Dose instructions
Take the missed dose as soon as you remember. If it is almost time for the next scheduled dose, then the missed dose can be skipped.
Overdose instructions
Contact your doctor if an overdose is suspected. Symptoms may include mental confusion, difficulty in walking, dizziness, skin irritation etc.
India
United States
Japan
Whenever you take more than one medicine, or mix it with certain foods or beverages, you're at risk of a drug interaction.
Interaction with Disease
Brain toxicity Major
The injectable form of this medicine should not be used in patients with brain damage, memory problems, anxiety, depression and other mental disorders. Your doctor will determine the best course of treatment after assessing the condition.
Impaired kidney function Major
This medicine should be used with caution in patients suffering from a kidney disease. Symptoms of the disease may worsen after the use of colistin. You may need a dose adjustment and more frequent clinical monitoring while using this medicine.
Colitis Moderate
Use of this medicine may cause severe irritation of the stomach and the intestine. Report any instance of colitis in the past or the present to the doctor. Appropriate diagnostic tests and clinical monitoring are advised before starting the treatment course with this medicine.
Interaction with Alcohol
Alcohol
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Lab Test
Lab
Information not available.
Interaction with Food
Food
Information not available.
Interaction with Medicine
Tacrolimus Major
Report the use of either of the medicine to the doctor. You may need a dose adjustment and frequent clinical monitoring to safely use these medicines together. Report incidences of loss of appetite, sudden weight gain, and fluid retention to the doctor immediately.
Vancomycin Moderate
Report the use of either of the medicine to the doctor. You may need a dose adjustment and frequent clinical monitoring to safely use these medicines together. Report incidences of loss of appetite, sudden weight gain, and fluid retention to the doctor immediately.
Ethinyl Estradiol Moderate
Use of this medicine may make oral contraceptives less effective. This may result in unintended pregnancies. Other methods of contraceptions should be discussed with the doctor before treatment with colistin is initiated.
Live cholera vaccine Major
Report the use of this medicine before taking a live cholera vaccine. Any live vaccine should be taken 14 days after stopping the use of colistin.
Streptomycin Major
Report the use of either of the medicine to the doctor. You may need a dose adjustment and frequent clinical monitoring to safely use these medicines together. Report incidences of hearing or vision loss to the doctor immediately.

Popular Questions & Answers

I am 36 years old. I have gas problem. Whenever gas is formed I have severe pain on y right side of body starting from head to toe. Pain is severe in head. please suggest medicine.

MBBS
General Physician, Greater Noida
I am 36 years old. I have gas problem. Whenever gas is formed I have severe pain on y right side of body starting fro...
Hi, it seems you are suffering from 1. Gastritis or hepatitis 2. Take an antacid 3-4 tsf 8 hrly 3. Get a blood investigation - liver function test done 4. Avoid fatty, oily meals 5. No fast food, no momos and samosas 6. No tea and coffee 7. Lots of water 8. Walk after meals 9. Eat less at nights 10. No soft drinks, hard drinks and no smoking recommended a private consultation for your limb pain after bp recordings of 3 days.

Hi I am 24. Basically feeling mentally disturb from many days. Actually when I was I scul, I had some frnds. They started teasing me, dstrbing me by calling at night. And all. I got tensed with all this. Had a fight with them regarding this. And all this increased. I left the place where. We used to leave. I wouldn't have courage to face them. Bcoz every time they would tease me. All this while I got in masturbating bcoz after masturbating I could feel relieved. Them I got in college. Fee of meeting all of them, made me avoid going to scul. I stayed at home for around a year or so. No one was there to talk for 3 years. Than I started studying and joined my dad work. I dad got I'll, I had to carry his work. Study suffer and could not complete professional course. A girl came in my life. I fell in love and propose her, she accepted after many proposal. But suddenly started ignoring me and one day said she doesn't love me. I started my studies after she came in my lyf. And passed a part of it. Now she also left. I an not happy at present with all this that has happened in last 6 years. I can't focus on work & study. Get angry and irritated. Forget small things. Feel like not worthy to live. Whom to consult. psychologist or psychiatrist. Am I wrong in any way. Help me.

B.Sc(Hons) Mumbai Univ., ND, MD - Alternate Medicine, Aroma Therap., Bach Flower Rem, Mental Health Cert.
Alternative Medicine Specialist, Mumbai
Hi I am 24.
Basically feeling mentally disturb from many days.
Actually when I was I scul, I had some frnds. They sta...
Hi I will prescribe some harmless but effective flower remedy. Mix 2 drops of Aspen+ 2 drops of Mimulus + 2 drops of Mustard +Cherry Plum 2 drops + 2 drops of Scleranthus + + 2 drops of White chestnut Mix these with 100 ml water and drink it every morning and night.(same dose) on empty stomach. If problem continues consult me online. These flower remedies are available in Homoeopathy pharmacy.

Hi I'm an adult I just wanted to know Is masturbation good or bad to health could you please explain.

MD - Psychiatry
Psychiatrist, Chennai
Hi I'm an adult I just wanted to know Is masturbation good or bad to health could you please explain.
Masturbation is a very healthy form of sexual outlet, do not feel guilty about it. Nearly 99% of men and more than 60% of women masturbate. It starts from adolescence and goes on in some people even till death. The pleasure (orgasm) from masturbation is said to be unique from sexual intercourse. In men, most of the liquid contains only water and some fructose and hormones. Hence it does not drain your energy. Many equate masturbation/ seminal fluid loss to lack of energy, impotency and so on. Many quacks, religious heads and pseudo healers also propagate the idea that masturbation is a disorder/ and wrongful behavior and instill fear on the mind of innocent men and women (we can see posters in train and bus stand, offering help for this behavior). Consult a psychiatrist, if you have excessive masturbation guilt or compulsive masturbation. Compulsive masturbation is when a person continues with frequent masturbation neglecting his/ her other work like education, job or social obligations. In fact masturbation reduces the sexual tension and helps focus on task at hand better.

Sir I am suffering fro more and more sweating in summer and winter as also in summer due toe more sweating dehydration occurs.

BHMS
Homeopath, Chennai
Hyperhidrosis is nothing but an expression of the disturbance in the inner hormonal balance and this is expressed in the form of the profuse discharge. Hence, it is required to be treated at the inner level rather than treating it by local application of cream and antibiotics. Homeopathy treats the person as a whole. It means that the treatment focuses on the patient as a person as well as his pathological condition. The medicines are selected after a full individualizing examination and case analysis, which includes the medical history of the patient, physical and mental constitution and so on. Homeopathy provides natural constitutional remedies for treating this condition from the roots and not just working on the symptom but repairs the derangement which is causing this. It offers excellent treatment which is effective, harmless, and without any side effects. It is also recommended in the most obstinate cases. Today homeopathic remedies are the best non surgical solution for hyperhidrosis or profuse sweating or perspiration. You can easily take an online consultation for further treatment guidance and permanent cure without any side effects

Popular Health Tips

How Ayurveda Helps Manage Genital Warts?

Bachelor of Ayurveda, Medicine and Surgery (BAMS)
Ayurveda, Kanpur
How Ayurveda Helps Manage Genital Warts?

Warts are small fleshy growths on human skin, which can happen anywhere over the body and are usually harmless, although they could be unsightly and if growing in certain areas, may be painful. Genital warts belong to that variety. Most warts are caused by HPV or the human Papilloma virus and genital warts are no different.

Causes of Genital warts:

Genital warts are usually contracted during sexual intercourse. During intercourse, tearing of skin and contact with an infected individual will pass of the virus to another person. This is how HPV is transmitted, which may result in genital warts. Other than being unsightly, genital warts can be painful if they are in position when they have friction against clothing and they may also obstruct the flow of urine requiring them to be removed expediently.

Treatment of genital warts in ayurveda:

Ayurveda has some great remedies to cure this problem. Let us have a look at a few of them:

  1. The onion and salt mixture remedy: This natural remedy has primarily two elements, which are onion and salt. To make this mixture you slice two onions, and sprinkle them with salt before leaving them overnight. In the morning, mash the onions into a thick paste and then pass it through a filter or sieve to extract juice. Apply this juice on the warts periodically for a few weeks until they either shrivel or fall off.
  2. The garlic paste remedy: This is another easy remedy which if applied consistently can bring great results fairly quickly. In this method you need to take a few cloves of garlic, crush them to a paste, apply this paste on the warts, cover the affected area with a bandage and leave it for an hour. After an hour remove the bandage and wash of the area. Repeat this for a few weeks and you should see the results.
  3. The potato remedy: This remedy would require you to follow the steps multiple times a day. Take a potato and cut it into slices. Use these slices to rub the affected area. This has to be followed up multiple times a day, preferable at least 3 or more times. Doing this for 2 to 3 weeks will bring results where the warts will either shrink up or fall off.
1 person found this helpful

Skincare: Get Rid of Skin Pigmentation Fast!

M.B.B.S, D.D.V.L, M.D DERMATOLOGY
Dermatologist, Bangalore
Skincare: Get Rid of Skin Pigmentation Fast!

Hyperpigmentation is a relatively harmless condition, but can affect a person’s self-image and psyche. This skin condition is characterized by dark patches on the skin due to exposure to UV radiation or as a sign of aging. It is caused by an excessive production of melanin in the body. Hyperpigmentation affects people of all ages and with all skin types. However, fair-skinned people are at a higher risk of suffering from this condition than dark skinned people.

This condition can be treated in a number of ways including:

  1. LaserLaser treatment for hyperpigmentation improves skin tone and boosts collagen production. With advancement in laser technology, scarring is no longer a very big risk with this form of treatment. Depending on the degree of hyperpigmentation argon or carbon dioxide lasers may be used in with short pulses or long pulses. Treatment can take anywhere between 30 to 45 minutes and is relatively pain free. 
  2. Chemical peelsChemical peels rid the skin of its top most layer and bring new cells to the surface. This gives the skin an even tone and eliminates dark spots and patchiness. A light salicylic acid or glycolic acid peel is ideal for hyperpigmentation treatment. This is often used in cases where the patient’s skin is resistant to over the counter topical treatment. The concentration of active ingredients in the peel depends on the skin tone. Mild skin discolouration and blotchiness can be treated with a superficial peel while age spots and freckles require a medium peel. 
  3. Topical ointments: Topical ointments are usually the first form of treatment for hyperpigmentation. Hydroquinone or retinol are the most commonly prescribed ointments. Broad spectrum sunscreen that offers protection against UVA and UVB rays can also help prevent further sun damage and dark spots. Skin lightening creams with soy or niacinamide as active ingredients also help brighten skin tones. 

Apart from these forms of treatment, there are also a number of home remedies for this condition. Some of these home remedies are:

  1. Rubbing a freshly sliced or the juice of a grated potato on the skin
  2. Applying a combination of cucumber and lemon juice on the skin
  3. A grated papaya face mask
  4. Soak almonds in milk overnight and then skin them and puree with the milk. Apply this mixture on the affected areas. 
  5. A mask of guava and banana pulp. Consult an Expert & get answers to your questions!
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Causes Of Genital Warts And Its Ayurvedic Treatment!

Bachelor of Ayurveda Medicine and Surgery (BAMS)
Ayurveda, Nashik
Causes Of Genital Warts And Its Ayurvedic Treatment!

Warts are small fleshy growths on human skin, which can happen anywhere over the body and are usually harmless, although they could be unsightly and if growing in certain areas, may be painful. Genital warts belong to that variety. Most warts are caused by HPV or the human Papilloma virus and genital warts are no different.

Causes of Genital warts:

Genital warts are usually contracted during sexual intercourse. During intercourse, tearing of skin and contact with an infected individual will pass of the virus to another person. This is how HPV is transmitted, which may result in genital warts. Other than being unsightly, genital warts can be painful if they are in position when they have friction against clothing and they may also obstruct the flow of urine requiring them to be removed expediently.

Treatment of genital warts in ayurveda:

Ayurveda has some great remedies to cure this problem. Let us have a look at a few of them:

  1. The onion and salt mixture remedy: This natural remedy has primarily two elements, which are onion and salt. To make this mixture you slice two onions, and sprinkle them with salt before leaving them overnight. In the morning, mash the onions into a thick paste and then pass it through a filter or sieve to extract juice. Apply this juice on the warts periodically for a few weeks until they either shrivel or fall off.
  2. The garlic paste remedy: This is another easy remedy which if applied consistently can bring great results fairly quickly. In this method you need to take a few cloves of garlic, crush them to a paste, apply this paste on the warts, cover the affected area with a bandage and leave it for an hour. After an hour remove the bandage and wash of the area. Repeat this for a few weeks and you should see the results.
  3. The potato remedy: This remedy would require you to follow the steps multiple times a day. Take a potato and cut it into slices. Use these slices to rub the affected area. This has to be followed up multiple times a day, preferable at least 3 or more times. Doing this for 2 to 3 weeks will bring results where the warts will either shrink up or fall off.
3 people found this helpful

How To Get Rid Of Skin Pigmentation?

Fellow of ACSI , Fellow of IADVL , MD - Dermatology , Venereology & Leprosy, MBBS
Dermatologist, Delhi
How To Get Rid Of Skin Pigmentation?

Hyperpigmentation is a relatively harmless condition, but can affect a person’s self-image and psyche. This skin condition is characterized by dark patches on the skin due to exposure to UV radiation or as a sign of aging. It is caused by an excessive production of melanin in the body. Hyperpigmentation affects people of all ages and with all skin types. However, fair-skinned people are at a higher risk of suffering from this condition than dark skinned people.

This condition can be treated in a number of ways including:

  1. Laser: Laser treatment for hyperpigmentation improves skin tone and boosts collagen production. With advancement in laser technology, scarring is no longer a very big risk with this form of treatment. Depending on the degree of hyperpigmentation, Q-switch Nd: YAG and Fractional laser may be used in with short pulses or long pulses. Treatment can take anywhere between 30 to 45 minutes and is relatively pain free. 
  2. Chemical peels: Chemical peels rid the skin of its top most layer and bring new cells to the surface. This gives the skin an even tone and eliminates dark spots and patchiness. A light salicylic acid or glycolic acid peel is ideal for hyperpigmentation treatment. This is often used in cases where the patient’s skin is resistant to over the counter topical treatment. The concentration of active ingredients in the peel depends on the skin tone. Mild skin discolouration and blotchiness can be treated with a superficial peel while age spots and freckles require a medium peel. 
  3. Topical ointments: Topical ointments are usually the first form of treatment for hyperpigmentation. Hydroquinone or retinol are the most commonly prescribed ointments. Broad spectrum sunscreen that offers protection against UVA and UVB rays can also help prevent further sun damage and dark spots. Skin lightening creams with soy or niacinamide as active ingredients also help brighten skin tones. Consult an expert & get answers to your questions!
300 people found this helpful

3 Most Effective Treatment to Remove Birthmarks!

MD - Dermatology, MBBS
Dermatologist, Patna
3 Most Effective Treatment to Remove Birthmarks!

Birthmarks are dark spots/blemishes that are present at birth or appear soon after. Most of them are harmless and while some disappear with time, some don't. Birthmarks may cause a person to be conscious of their appearance and some types of marks may even pose health problems. You can opt for birthmark removal for cosmetic or health reasons.

Types of birthmarks

The two major types of birthmarks are vascular birthmarks, which are caused due to the incorrect formation of blood vessels; and pigmented birthmarks that are caused due to an overgrowth of pigmentation cells.

Common vascular birthmarks are 3 types:

- Haemangiomas: Bright red or bluish marks that may appear above or below the skin's surface.
- Port-wine stains: They are discolorations found mainly on the neck, face arms or legs, which look like wine was spilled on that area of the body.
- Macular stains: These are faint red marks often found on the forehead, eyelids, nape of the neck, nose or the upper lip.

Pigmented birthmarks are generally of 3 types- Cafe-au-lait spots, which are common coffee colored spots; Mongolian spots that are flat, bluish-gray patches on the lower back or buttocks; and moles that may be tan or black, flat or raised and may have hair growing out of them. Moles may develop into skin cancer.

So, in cases where a birthmark can be potentially fatal for your health, it's best to get it removed.

Here are the different ways you can choose from if you intend to get your birthmark removed.

1. Laser surgeryIt's a widely popular birthmark procedure, especially for port-wine stains. A yellow light laser, called flashlamp pumped a dye laser, is commonly used for treating and removing birthmarks in children. Haemangiomas are generally treated with a pulsed eye laser when they start to grow in size and become thicker than before.

2. Surgery - Surgical excision can help remove a birthmark and minimize the resulting scar. Mongolian birthmarks, port-wine stains, and haemangiomas can be treated with surgery.

3. Cryosurgery and Electrodessication - Cryosurgery is the application of extreme cold to the affected area to destroy the diseased tissue. Electrodessication refers to the destruction of tissues by dehydration induced by a high-frequency electric current.

6 people found this helpful