Dolo 650 MG Tablet belongs to Nonsteroidal Anti-inflammatory Drugs class of medicines. It is a mild analgesic used to treat fever and is most commonly used pain reliever. It is used to relieve pain in case of a backache, a headache, arthritis and a toothache. It also reduces pain in the body caused due to fever. The patients who have cancer or have undergone surgery are also given this medicine to help them tolerate the pain. Its main constituent is paracetamol. It is a pain relief medication that is administered both orally and intravenously. It selectively inhibits enzyme function in the brain which allows it to treat pain and fever. It brings down elevated body temperature by acting on heat regulatory centers in the brain. It activates certain receptors in the brain that inhibit pain signals. For adults, the usually advised dose of Dolo 650 MG Tablet is 1-2 tablets which are 500mg or 650mg. There should be a interval of at least 4 hours between 2 consecutive doses of this medicine. The total dose of this medicine should not exceed 4g per day. It is safe to take this medicine during pregnancy. It can be taken once for headache but should not be made a habit.
It is safe to drive after taking Dolo 650 mg tablet as it does not make you feel sleepy.
The use of Dolo 650 mg Tablet affects the kidney mildly. If the patient is suffering from kidney disease it can cause major effects.
The use of Dolo 650 mg Tablet affects the liver mildly. If the patient is suffering from liver impairment it can cause major effects.
Dolo 650 mg tablet is known to interact with the following diseases:
Alcoholism – the patient suffering with chronic alcohol use should use this medicine with caution as it may result in serious liver injury.
Liver disease - any patient with a history of liver impairment or current liver disease must use this medicine with caution as it can cause major liver injury.
Chronic malnutrition – patient suffering from chronic malnutrition must take this medicine with great caution as it may cause adverse effects.
The interaction of Dolo 650 mg tablet can e very dangerous as it may trigger the side effects like dizziness, fatigue, fever, joint pain etc. It can also have severe effect on liver.
The interaction of Dolo 650 mg tablet is unknown with food. It can be taken both with and without food.
Dolo is known to interact with the following medicines Carbamazepine, Methotrexate, Phenytoin, Sodium Nitrite, Leflunomide prilocaine, Corticosteroids, Aspirin, Antihypertensives and Anticoagulants.
Paracetamol is one of the most commonly consumed medicine to deal with minor pain, body ache, headache, fever etc. It can also be used for getting temporary relief from arthritis pain. This is readily available over the counter and can be obtained without a prescription. The dosage is available in the form of syrup, powder, solution, tablet, suspension, suppository etc.
Considerations to make before consuming paracetamol:
The risk of the medicine must be considered before consuming it. The health care professional should be reported for any allergy related problems. For a person facing allergy, one should carefully read the label before consuming it. Interaction of 2 paracetamol can prove to be fatal sometimes. The dosage, therefore, of these medicines should be consulted with the doctor. This being said, there are certain medicines which act best when they are consumed together. The outcome of the effect is based on the disease one is facing. The effectivity of this medicine can get influenced if the patient has a history of abusing alcohol, suffered from liver and kidney diseases in the past etc.
Proper use of paracetamol:
Paracetamol should be consumed with care. Prolonged consumption can damage the liver. The maximum dosage of this medicine should not exceed 3k milligrams in a day. This can be consumed before or after the consumption of food. Paracetamol in the form of syrup should be shaken well before use. There should be a minimum time span of 4-6 hours between two dosages of paracetamol. In the case of a missed dosage, the medicine should be taken as early as possible. It does not prove to be fatal in case a dosage is missed. Finally, it should be ensured that paracetamol is stored at room temperature and freezing is avoided.
It is of utmost importance to check the progress of the patient in case one is consuming paracetamol. During the process of consuming paracetamol, symptoms such as dark urine, stomach ache, nausea, weakness etc should be immediately reported to the stomach. For patients suffering from diabetes, any drastic change in the blood sugar level due to the consumption of paracetamol should be immediately reported to the doctor.
Certain rare side-effects of paracetamol include lower back pain, bruising, fever, cloudy urine, tarry stools, yellowish skin, bruising, skin rash, itching etc. Some common symptoms of overdosage of paracetamol include increased sweating, tenderness, swelling and pain in the lower abdomen area, vomiting and nausea, diarrhea, appetite loss, increased thrust etc. If any of these symptoms are faced during the consumption of paracetamol are reported, a healthcare professional should be immediately consulted to avoid any further complication. Frequent usage should also be avoided. If you wish to discuss about any specific problem, you can consult a General Physician.
As per a study conducted by the Copenhagen University Hospital, it was revealed that consuming paracetamol during pregnancy can be detrimental for your baby, as it can weaken the development of the reproductive system of female offspring. The research was published in Endocrine Connections journal.
Although, paracetamol is an over-the-counter treatment for pain relief that is commonly taken by pregnant women worldwide. The study was conducted on three individual rodents and the results indicated that the rodents, who were given paracetamol during pregnancy at doses equivalent to those that of a pregnant woman may take for pain relief, produced female offspring with fewer eggs.
Further, Dr. Kristensen said, "Although this may not be a severe impairment to fertility, it is still of real concern since data from three different labs all independently found that paracetamol may disrupt female reproductive development in this way, which indicates further investigation is needed to establish how this affects human fertility."