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Paracetamol

Prescription vs.OTC: Prescription by Doctor required
Last Updated: February 22, 2019

Paracetamol, classified as a mild analgesic, is used to treat fever and is the most commonly used pain reliever. It is used to relieve pain in case of a backache, a headache, arthritis and a toothache. It reduces pain in the body caused due to fever. It is often given to patients who suffer from cancer or have undergone surgery, to help them cope up with the pain. Paracetamol is normally administered orally or rectally, it is also available for intravenous administration.

Paracetamol does not have any serious side effects. It is safe to use this medicine during pregnancy and breastfeeding. However, in rare cases skin rashes may occur accompanied by nausea, stomach pain, and loss of appetite. You should stop using Paracetamol if you experience an allergic reaction to it or notice any other serious symptoms like dark urine, clay-colored stools or jaundice. Overdosing may result in liver failure.

You should not take Paracetamol if –

  • You are allergic to Paracetamol
  • You are suffering from a serious liver disorder.
  • You normally consume more than 3 alcohol beverages per day or have a history of alcoholism.

There are several drugs that may interact with Paracetamol. Inform your doctor about all the other medications that you take including vitamins, minerals, prescribed drugs, over the counter drugs and herbal products. For adults Paracetamol the general dose for fever and pain is 325-650 mg tablets once in every 4 to 6 hours or 1000mg tablets once in every 6 to 8 hours. It is advised to be guided by the doctor’s prescription and never to exceed the prescribed dosage.

Information given here is based on the salt and content of the medicine. Effect and uses of medicine may vary from person to person. It is advicable to consult a Internal Medicine Specialist before using this medicine.

Paracetamol is used to provide temporary relief from fever without treating the underlying cause.

Headache

Paracetamol is used to relieve acute headaches including migraine.

Muscle Pain

Paracetamol is used to relieve mild to moderate pain in the muscles.

Menstrual Cramps

Paracetamol is used to relieve pain and cramping associated with menstrual cycle in women.

Post Immunization Pyrexia

Paracetamol is used in the treatment of pain and fever that sets in after one has taken vaccinations.
Paracetamol is used to relieve joint pain including mild to moderate pain in arthritis.
Paracetamol is not recommended if you have a known allergy to this medicine.

Analgesic Nephropathy (Kidney Disease)

Paracetamol is not recommended if you suffer from impaired kidney function due to excessive usage of painkillers or otherwise.
Paracetamol is metabolised by the liver and is not recommended if you suffer from impaired liver function.
In addition to its intended effect, Paracetamol may cause some unwanted effects too. In such cases, you must seek medical attention immediately. This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.

Nausea or Vomiting

Moderate Common
Paracetamol can cause nausea and vomiting along with other symptoms like abdominal pain, diarrhoea, dry mouth etc.

Fever

Moderate Common
Paracetamol can cause low to moderate fever with or without chills.

Allergic skin reaction

Moderate Less Common
Paracetamol can cause red spots on skin, rashes, hives and itching.

Gastric / Mouth Ulcer

Moderate Less Common
Paracetamol can cause discolouration of urine along with sudden decrease in amount.

Anemia

Moderate Rare
Paracetamol can cause anemia like symptoms in some patients.

Fatigue

Minor Less Common
Paracetamol can cause tiredness and weakness with pain and twitching of the muscle.

Stevens-Johnson Syndrome

Major Rare
Paracetamol can cause this rare but potentially fatal allergic reaction of the skin that requires immediate treatment.

How long is the duration of effect?

The effect lasts for an average of 4-6 hours.

What is the onset of action?

The effect of Paracetamol (primary constituent of Paracetamol) can be observed within an hour of oral administration. When given in the form of an intravenous injection, the pain-relieving action starts in 5-10 minutes. For fever reduction, the time taken is about 30 minutes.

Are there any pregnancy warnings?

This medicine is not known to cause any harm to the fetus. But the evidence is inadequate and it should be used only when necessary after consulting a doctor. Oral administration of the medicine should be preferred over intravenous route.

Is it habit forming?

No habit forming tendencies were reported.

Are there any breast-feeding warnings?

This medicine is safe to use during breastfeeding. It is advised to consult your doctor before taking this medicine. Any incidence of rashes on skin or diarrhea in the infant should be reported.

Missed Dose instructions

Paracetamol is usually taken as and when required. If the medicine is taken on a regular basis, then the missed dose should be taken as soon as possible. You should not take the missed dose if it is time for taking the next scheduled dose.

Overdose instructions

Paracetamol overdosage could cause harmful effects to the body. Early symptoms are loss of appetite, nausea, vomiting, stomach pain while late symptoms include yellowing of skin and eye, severe abdominal pain and dark color urine.

India

United States

Japan

Below is the list of medicines, which contains Paracetamol as ingredient
Elder Pharmaceuticals Ltd
Elder Pharmaceuticals Ltd
Elder Pharmaceuticals Ltd
Med Manor Organics Pvt Ltd.
Abbott India Ltd
Neon Laboratories Ltd
Parenteral Drugs (India) Ltd
Biochem Pharmaceutical Inds
Neon Laboratories Ltd
Group Pharmaceuticals Ltd
Veritaz Healthcare Ltd
Ipca Laboratories Pvt Ltd.
Unichem Laboratories Ltd
Glaxosmithkline Pharmaceuticals Ltd
Micro Labs Ltd
Mankind Pharmaceuticals Ltd
Themis Medicare Ltd
Paracetamol is a pain relief medication that is administered both orally and intravenously. It selectively inhibits enzyme function in the brain which allows it to treat pain and fever. It activates certain receptors in the brain that inhibit pain signals.
Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

Interaction with Disease

Alcoholism

Major
This medicine should be given with extreme caution if you are a chronic alcoholic. Usage of alcohol should be avoided and any symptoms like nausea, fever, rashes, darkened urine should be reported to the doctor on priority.

Liver Disease

Major
Paracetamol should be given with extreme caution to if you are suffering from impaired liver functioning disease. Symptoms like nausea, fever, rashes, darkened urine should be reported to the doctor on priority. Clinical monitoring of liver function should be done at regular intervals.

Interaction with Alcohol

N/A

Major
You should avoid consuming alcohol while taking this medicine. Symptoms like fever, chills, rashes, joint pain and swelling, excessive weakness, nausea should be immediately reported to the doctor.

Interaction with Lab Test

5-HIAA Urine Test

Moderate
You may get a false-positive result for this test if you take Paracetamol.

Interaction with Food

Food

Information not available.

Interaction with Medicine

Carbamazepine

Moderate
Paracetamol should not be taken with Carbamazepine. Usage of either of the drugs should be reported to the doctor. Any symptoms like fever, chills, joint pain, skin rash, loss of appetite should be reported promptly.

Phenytoin

Moderate
Paracetamol should not be taken with Phenytoin. Usage of either of the drugs should be reported to the doctor. Any symptoms like fever, chills, joint pain, skin rash, loss of appetite should be reported promptly.

Sodium Nitrite

Major
Paracetamol should not be taken while on Sodium Nitrite. Symptoms like discoloration of skin, rashes, headache, dizziness, increased heartbeat should be promptly reported to the doctor.

Leflunomide

Major
Paracetamol should not be taken while on leflunomide. Usage of either of the drug should be reported to the doctor. Symptoms like fever, chills, nausea, yellowing of skin should be promptly reported.

Prilocaine

Major
Paracetamol should not be taken while on Prilocaine. Symptoms like discoloration of skin, rashes, headache, dizziness, increased heartbeat should be promptly reported to the doctor.

Ques: What is Paracetamol?

Ans: Paracetamol is a medication which has Paracetamol as active ingredients present in it. This medicine performs its action by obstructing the release of pain and fever chemical messengers. It is also used to avoid muscle pain and arthritis symptoms. Paracetamol is used to treat conditions such as Post immunization pyrexia, menstrual cramps and fever.Paracetamol is a medication which has Paracetamol as active ingredients present in it. This medicine performs its action by obstructing the release of pain and fever chemical messengers. It is also used to avoid muscle pain and arthritis symptoms. Paracetamol is used to treat conditions such as Post immunization pyrexia, menstrual cramps and fever.

Ques: What are the uses of Paracetamol?

Ans: Paracetamol is used for the treatment and prevention from conditions and symptoms of diseases like Post immunization pyrexia, menstrual cramps and fever. Besides these, it can also be used to treat conditions like muscle pain and arthritis symptoms. The patient should inform the doctor about any ongoing medications and treatment before using Paracetamol to avoid undesirable effects.

Ques: What are the Side Effects of Paracetamol?

Ans: This is a list of possible side-effects which may occur due to the constituting ingredients of Paracetamol. This is not a comprehensive list. These side-effects have been observed and not necessarily occur. Some of these side-effects may be serious. These include allergic reaction, gastric ulcers, fatigue and anemia. Apart from these, using Paracetamol may further lead to stevens johnson syndrome, nausea and vomiting. If any of these symptoms occur often or on daily basis, a doctor should be urgently consulted.

Ques: What are the instructions for storage and disposal Paracetamol?

Ans: Paracetamol should be stored at room temperature, away from heat and direct light. Keep it away from the reach of children and pets. A doctor should be consulted regarding the dosage of Paracetamol. The patient should consult a doctor for its further uses and side effects and should inform the doctor about any ongoing medications and treatment before using to avoid undesirable effects.
Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

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Table of Content
About Paracetamol
What are the uses of Paracetamol
What are the contraindications of Paracetamol ?
What are the side effects of Paracetamol ?
Key highlights of Paracetamol
What are the dosage instructions?
Where is the Paracetamol approved?
Medicines containing Paracetamol
How does medicine works?
What are the interactions of Paracetamol ?
Paracetamol Frequently Asked Questions (FAQs):