Calpol 650 MG Tablet

Calpol 650 MG Tablet is used a pain-relieving medication. It is primarily used to treat acute pain. The conditions of acute pain include backache, headache, arthritis and toothache, etc.

The active ingredient falls under the class of analgesics, belonging to the category of NSAID. This medication also reduces pain in the body caused due to fever.

Also, it reduces pain in the body caused due to fever. This medication is often given to patients who suffer from cancer or have undergone surgery, to help them cope up with the pain. You should not consume this tablet if you are:

• Allergic to this medicine.
• Suffering from a serious liver disorder.
• Normally consume more than 3 alcohol beverages per day or have a history of alcoholism.

You must not take the medicine in more than the amount prescribed or longer than the prescribed period. It can be taken with food or without it, but you must take it, in the same way, every day.

The medicine must be swallowed whole, without trying to crush, break or mixing it in water. As it is a pain reliever, it is unlikely that you will miss a dose. In case you do, refrain from taking two doses together to make up for the missed one.

This medication does not have any serious side effects. It is safe to use this medicine during pregnancy and breastfeeding. However, in rare cases, skin rashes may occur accompanied by nausea, stomach pain, and loss of appetite.

There are several drugs that may interact with Calpol. Inform your doctor about all the other medications that you take including vitamins, minerals, prescribed drugs, over-the-counter drugs, and herbal products.

For adults Paracetamol the general dose for fever and pain is 325-650 mg tablets once in every 4 to 6 hours or 1000mg tablets once in every 6 to 8 hours. It is advised to be guided by the doctor’s prescription and never to exceed the prescribed dosage.

For treating Paracetamol toxicity, Acetylcysteine 140 mg/kg is administered orally (loading) followed by 70 mg/kg every 4 hours for 17 doses.

Therapy should be initiated based upon laboratory analysis suggesting high probability of hepatotoxic potential. Activated charcoal is very effective at binding acetaminophen.

Maintain adequate hydration (2-3 L/day of fluids unless instructed to restrict fluid intake). This medication will not reduce inflammation; consult prescriber for anti-inflammatory, if needed.

For treating Paracetamol toxicity, Acetylcysteine 140 mg/kg is administered orally (loading) followed by 70 mg/kg every 4 hours for 17 doses.

Therapy should be initiated based upon laboratory analysis suggesting high probability of hepatotoxic potential. Activated charcoal is very effective at binding acetaminophen.

Maintain adequate hydration (2-3 L/day of fluids unless instructed to restrict fluid intake). This medication will not reduce inflammation; consult prescriber for anti-inflammatory, if needed.

The medicine is useful against the following conditions:

• Fever

• Headache

• Muscle Pain

• Menstrual Cramps

• Post Immunization Pyrexia

• Arthritis

• Allergy

• Analgesic Nephropathy (Kidney Disease)

• Liver Disease

Common side effects of this medicine include:

• Nausea Or Vomiting

• Allergic Skin Reaction

• Gastric / Mouth Ulcer

• Anemia

• Fatigue

• Stevens-Johnson Syndrome (Sjs)

• Abdominal Pain

• How long is the duration of effect?

  The effect lasts for an average of 4-6 hours.

• What is the onset of action?

  The effect of medication can be observed within an hour of oral administration.

• Are there any pregnancy warnings?

  This medication should be avoided by pregnant women unless suggested by the doctor. The effect of this medication on fetus is not clearly established and hence, doctor consultation is recommended before consumption.

• Is it habit forming?

  No habit forming tendencies were reported.

• Are there any breast-feeding warnings?

  This medication is safe to use during breastfeeding. Before using this medicine consultation from a doctor is recommended. If you see any incidence of rashes on skin or diarrhea in the infant report it.

• Does this affect liver function?

  Appears to be well tolerated in cirrhosis; serum levels may need monitoring with long-term use.

• Does this affect kidney function?

  Dose adjustment is needed in case of renal impairment. Dosing interval in renal impairment:
  • Clcr 10-50 mL/minute: Administer every 6 hours.
  • Clcr <10 mL/minute: Administer every 8 hours (metabolites accumulate)
  • Hemodialysis: Moderately dialyzable (20% to 50%).
  Consult your doctor before taking this medication.

• Is It safe with alcohol?

  Excessive intake of alcohol may increase the risk of acetaminophen-induced hepatotoxicity; avoid or limit alcohol intake.

Below is the list of medicines, which have the same composition, strength and form as Calpol 650 MG Tablet , and hence can be used as its substitute.

• Amol 650 MG Tablet

  Unichem Laboratories Ltd

• Doliprane 650 MG Tablet

  Abbott Healthcare Pvt. Ltd

• Pyrakem 650 MG Tablet

  Alkem Laboratories Ltd

• Pyrexon 650 MG Tablet

  Wockhardt Ltd

• K Par 650 MG Tablet

  Kineses Laboratories

• Missed Dose instructions

  This medication is usually taken as and when required. If the medicine is taken on a regular basis, then the missed dose should be taken as soon as possible. You should not take the missed dose if it is time for taking the next scheduled dose.

• Overdose instructions

  This medication overdosage could cause harmful effects to the body.

The drug is a pain relief medication that selectively inhibits enzyme function in the brain which allows it to treat pain and fever. It activates certain receptors in the brain that inhibit pain signals.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

• Interaction with Alcohol

  You should avoid consuming alcohol while taking this medicine. Symptoms like fever, chills, rashes, joint pain and swelling, excessive weakness, nausea should be immediately reported to the doctor.

• Interaction with Lab Test

  5-HIAA Urine Test

  You may get a false-positive result for this test if you take Calpol 650 MG Tablet.

• Interaction with Medicine

  One must take caution while taking this medicine. This medication may interact with other medication like Ketoconazole, Metformin, Anti-hypertensives if administered concomitantly. Also, Barbiturates, carbamazepine, hydantoins, sulfinpyrazone can increase the hepatotoxic potential of acetaminophen; chronic ethanol abuse increases the risk for acetaminophen toxicity; effect of warfarin may be enhanced

• Interaction with Disease

  This medication should be used with caution in patients with an active liver disease.

• Interaction with Food

  May slightly delay absorption of extended-release preparations; rate of absorption may be decreased when given with food high in carbohydrates.