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Overview

Detab Plus Tablet

Manufacturer :  Depsons Pharma
Medicine Composition :  Doxycycline
Prescription vs OTC : Prescription by Doctor required

About Detab Plus Tablet

Detab Plus Tablet is an antibiotic medicine. It is primarily used to treat infections of lungs and reproductive organs (some sexually transmitted diseases). This drug may also be used as part of combination therapy to treat severe acne and to prevent malaria.

This medication belongs to a class of medications called tetracyclines which block a bacterial protein from being made and therefore prevents the growth of bacteria. It is also used to treat bacterial infections which include intestinal infections, skin infections, eye infections, urinary tract infections, respiratory infections, and others.

Common side effects include diarrhoea, a red rash, nausea, vomiting, flue symptoms, skin allergies and an increased risk of a sunburn. In young children and pregnant women it may result in permanent problems with teeth and bone development. It is considered safe in people who are breastfeeding.

To make sure doxycycline is safe for you, tell your doctor if you have :

Also inform the doctor if you also take isotretinoin including Claravis, Amnesteem or Sotret or you take seizure medicine or any blood thinners. It is best taken by mouth on an empty stomach, at least 1 hour before or 2 hours after a meal, usually 1 or 2 times every day.

Drinking lots of fluids is highly recommended while taking this medicine. If stomach upset occurs, taking it with food may help even though its effect may decrease a little. It is advised to not lie down for 10 minutes after taking this medication.

Take this medication 2 to 3 hours before or after taking products like antacids, quinapril, didanosine solution, vitamins or minerals, dairy products, and calcium-enriched juice. Follow your doctor's instructions carefully. Your dosage will be based on your medical condition, weight, age and response to treatment. For the best effect, take this antibiotic at evenly spaced times.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    What are the uses of Detab Plus Tablet

    • Bacterial Infections

    • Rickettsial Infection

    • Chlamydia Infection

    • Mycoplasma Pneumonia

    • Malaria Prophylaxis

    • Syphilis

    • Community Acquired Pneumonia

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    What are the contraindications of Detab Plus Tablet ?

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    What are the side effects of Detab Plus Tablet ?

    • Discoloration Of Teeth

    • Esophagitis

    • Increased Intracranial Pressure

    • Rash

    • Photosensitivity

    • Nausea

    • Diarrhoea

    • Neutropenia

    • Liver Toxicity

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    Key highlights of Detab Plus Tablet

    • Is It safe with alcohol?

      Interaction with alcohol is unknown. Please consult your doctor.

    • Are there any pregnancy warnings?

      Detab Plus Tablet is unsafe to use during pregnancy.
      There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.

    • Are there any breast-feeding warnings?

      Detab Plus Tablet is probably safe to use during lactation. \nLimited human data suggests that the drug does not represent a significant risk to the baby.

    • Is it safe to drive while on this medicine?

      Detab Plus Tablet may make you feel dizzy, sleepy, tired, or decrease alertness. If this happens, do not drive.
      Visual disturbances such as blurring of vision may occur during treatment with doxycycline.

    • Does this affect kidney function?

      Detab Plus Tablet is safe to use in patients with kidney disease. No dose adjustment of Detab Plus Tablet is recommended.
      However, talk to your doctor if you have any underlying kidney disease.

    • Does this affect liver function?

      Detab Plus Tablet should be used with caution in patients with liver disease. Dose adjustment of Detab Plus Tablet may be needed. Please consult your doctor.

    • What is the onset of action?

      The action of the medicine will be produced within 2 hours after the ingestion of it.

    • How long is the duration of effect?

      The medicine will remain active for 12-15 hours.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    What are the dosage instructions?

    • Missed Dose instructions

      The missed dose should be taken as soon possible. It is advisable to skip the missed dose if it's already time for your next scheduled dose.

    • Are there any overdose instructions?

      Seek emergency medical treatment or contact the doctor in case of overdose.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    Where is the Detab Plus Tablet approved?

    • India

    • United States

    • Japan

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    How does this medication work?

    Detab Plus Tablet is a synthetic tetracycline with antimicrobial properties. It binds to the 30S ribosomal subunit and thus prevents the binding of minoacyl-tRNA to the mRNA-ribosome complex which in turn prevents protein synthesis in the bacterium.

      Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

      What are the interactions of Detab Plus Tablet ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

        test
      • Interaction with Lab Test

        If the patient is taking Detab Plus Tablet it may give false-negative urine glucose. The patient must inform the doctor about the same.
      • Interaction with Medicine

        The patient must avoid concomitant use of :
        • CYP3A3/4 enzyme substrate
        • Iron and bismuth subsalicylate may decrease Detab Plus Tablet bioavailability
        • Barbiturates, phenytoin, and carbamazepine decrease Detab Plus Tablet half-life
        • Increased effect of warfarin
      • Interaction with Food

        Administration with iron, calcium, milk or other dairy products may decrease Detab Plus Tablet absorption. May decrease absorption of calcium, iron, magnesium, zinc, and amino acids.Thus food items containing these must be avoided.

      FAQs about Detab Plus Tablet

      • Ques : What is Detab Plus Tablet?

        Ans : Detab Plus Tablet is an antibiotic medicine and primarily used to treat infections.

      • Ques : What are the uses of Detab Plus Tablet?

        Ans : It is helpful in treating infections of lungs and reproductive organs (some sexually transmitted diseases).

      • Ques : What are the side effects of Detab Plus Tablet?

        Ans : Photosensitivity, pain, swelling, redness, vomiting, nausea and diarrhea are the most common side effects that may occur.

      • Ques : Can I drink milk while taking Detab Plus Tablet?

        Ans : It is suggested to avoid consuming milk during the course of medication with this drug. This is because the consumption of milk products can decrease the absorption of Detab Plus Tablet.

      • Ques : How long after taking Detab Plus Tablet can I eat?

        Ans : Do not eat for 2 hours after consuming this drug as doing so may decrease the absorption of this medicine.

      • Ques : Can I take Detab Plus Tablet with food if it's causing stomach upset?

        Ans : You must not stop taking this drug without informing your doctor. This drug should not be used if you have consumed any milk product as otherwise you may have an upset stomach.

      • Ques : How long does Detab Plus Tablet take to work?

        Ans : This medication starts in action just after consuming it. However, one must complete the full course of treatment otherwise the symptoms may recur.

      • Ques : Can the use of Detab Plus Tablet cause diarrhea?

        Ans : The use of this drug may cause diarrhea in some patients. In fact, this is one of the most common side effects that may occur after consuming this medicine.

      • Ques : Can Detab Plus Tablet be used in children?

        Ans : As per American Academy of Pediatrics, Detab Plus Tablet can be used in children of all ages, however it should not be used for more than 21 days.

      • Ques : Does Detab Plus Tablet work in acne?

        Ans : Detab Plus Tablet is helpful in treating acne. It is a common medicine prescribed as an oral antibiotic to treat acne by reducing the number of bacteria.

      References

      • Doxycycline-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 27 May 2022].Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/doxycycline

      • Doxycycline-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 27 May 2022].Available from:

        https://go.drugbank.com/drugs/DB00254

      • DOXYCYCLINE Tablet,solution-DailyMed [Internet].dailymed.nlm.nih.gov 2022 [Cited 27 May 2022].Available from:

        https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=DOXYCYCLINE

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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