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Chloroquine

Prescription vs.OTC: Prescription by Doctor required

Chloroquine is an anti-malarial medication to prevent and treat malaria, a disease caused by parasites in countries where malaria is common. It works by interfering with the growth of parasites in the red blood cells of the human body. Chloroquine is also used to treat infections caused by amoebae occurring outside of the intestines, lupus erythematosus and rheumatoid arthritis. It is administered orally. Functioning of the liver and blood cell count should be checked from time to time while taking this medicine.

This medicine is not recommended in patients with the eye or ear disease and who have faced serious allergic reactions to any antimalarials in the past. Discus with your doctor the risks of taking this medication if you suffer from psoriasis, porphyria, liver disorder, alcoholism, epilepsy or other seizure disorder. It is not known if the medicine can cause harm to a baby so it is a safer option to not take this medicine during pregnancy or breastfeeding.

Common side effects include muscle problems, diarrhoea, loss of appetite, and skin rashes. Some serious side effects may include problems with vision, low blood cell levels, muscle damage and seizures.

Usual initial dosage for acute malaria and hepatic amoebiasis in adults is 600 mg, then dose is decreased to 300 mg a day. For severe malaria, 25 mg/kg should be given in several infusions over 30-32 hr. Chloroquine should be taken with food. Ensure that the course of treatment is completed before discontinuing the doses to prevent the spread of infection. The effect of this medicine can be observed in 1 to 2 hours and lasts for an average duration of 9 to 15 days

Information given here is based on the salt and content of the medicine. Effect and uses of medicine may vary from person to person. It is advicable to consult a Internal Medicine Specialist before using this medicine.

Malaria prophylaxis

Chloroquine is used as prophylaxis for malaria.
Chloroquine is used in the treatment of malaria characterized by muscle pain, fever with chills and fatigue.

Amebiasis

Chloroquine is used in the amebiasis which is a parasitic infection that affects the intestine and amebic liver abscess caused by Entamoeba histolytica.
Not recommended in patients with known allergy to 4-aminoquinoline compounds.

Retinal or visual field changes

Not recommended in patients with any vision impairment.
In addition to its intended effect, Chloroquine may cause some unwanted effects too. In such cases, you must seek medical attention immediately. This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.

Blurred vision

Major Rare

Confusion

Major Rare

Diarrhea

Major Rare

Dizziness

Major Rare

Skin rash

Major Rare

Hair loss

Minor Rare

Increased sensitivity of the skin to sunlight

Minor Rare

How long is the duration of effect?

The effect of this medicine lasts for an average duration of 9 to 15 days.

What is the onset of action?

The effect of this medicine can be observed in 1 to 2 hours.

Are there any pregnancy warnings?

This medicine is not recommended in pregnant women unless absolutely necessary.

Is it habit forming?

No habit forming tendencies were reported.

Are there any breast-feeding warnings?

This medicine is known to excreted through breast milk. It is not recommended in for breastfeeding women.

Missed Dose instructions

If you miss a dose of Chloroquine, take the missed dose as soon as you remember. If it’s almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

Overdose instructions

Seek emergency medical treatment or contact the doctor in case of an overdose.

India

United States

Japan

Below is the list of medicines, which contains Chloroquine as ingredient
Ipca Laboratories Pvt Ltd.
Shreya Life Sciences Pvt. Ltd
Que Pharma Pvt. Ltd
Ipca Laboratories Pvt Ltd.
Ipca Laboratories Pvt Ltd.
Leo Pharmaceuticals
Leo Pharmaceuticals
Leo Pharmaceuticals
Merck Consumer Health Care Ltd
Indswift Laboratories Ltd
Themis Medicare Ltd
Bayer Pharmaceuticals Pvt. Ltd
Abbott Healthcare Pvt. Ltd
Ipca Laboratories Pvt Ltd.
Jagsonpal Pharmaceuticals Ltd
Merck Consumer Health Care Ltd
Indoco Remedies Ltd
Shreya Life Sciences Pvt. Ltd
Indswift Laboratories Ltd
Chloroquine is an antimalarial drug that works by inhibiting the enzyme heme polymerase which prevents the conversion of the toxic heme molecules to the nontoxic hemazoin, in parasites that cause malaria. The toxic heme accumulates leading to death of the parasite.
Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

Interaction with Disease

Oculotoxicity

Major
This medicine is not recommended in patients with the eye disorder. Close monitoring of eye function is necessary. The treatment should be discontinued if any symptoms of blurred vision, difficulty in reading appear.

Interaction with Alcohol

Alcohol

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Interaction with Lab Test

Lab

Information not available.

Interaction with Food

Food

Information not available.

Interaction with Medicine

Ethambutol

Moderate
These medicines may increase the risk of nerve damage if given together. Any symptoms of numbness, tingling or burning sensation in feet, hands should be informed to the doctor. An alternate medicine should be considered based on the clinical condition.

Fluconazole

Moderate
These medications may increase the risk of irregular heart rhythm. Inform the doctor if you are receiving any heart medications. Close monitoring of heart function is necessary. Discontinue the treatment if you develop any symptoms of palpitations, dizziness, and difficulty in breathing.

Tramadol

Major
These medications may increase the risk of seizures if taken together. Inform the doctor if you are having any history of seizures or head injury. Any symptoms of seizures should be reported to the doctor. An alternate class of medication should be considered based on the medical condition.

Quinidine

Major
These medications may increase the risk of irregular heart rhythm. Inform the doctor if you are receiving any heart medications. Close monitoring of heart function is necessary. Discontinue the treatment if you develop any symptoms of palpitations, dizziness, and difficulty in breathing.
What are you using Chloroquine for?
Other
Malaria
Malaria prophylaxis
Pain
Amebiasis
How much was the improvement?
Excellent
Poor
Average
How long did it take before seeing improvement?
Within 2 hours
More than 2 days
Within 2 days
Within 6 hours
How frequently did you take this medicine?
Once a day
Four times A Day
How did you take this medicine?
Empty stomach
With or without food
With Food
What were the side effects of this medicine?
Blurred vision
Confusion
Diarrhea
Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

Popular Questions & Answers

If a patient has fever with rigors and vomiting also which drugs should be used to check vomiting along with chloroquine phosphate? Can ondansetron be used in combination with chloroquine phosphate ?

MBBS
General Physician, Cuttack
If a patient has fever with rigors and vomiting also which drugs should be used to check vomiting along with chloroqu...
1.Fever with rigors can be due to so many reasons like urinary tract infection, malaria etc. 2.Don't take chloroquine without checking your blood for MP. Chloroquine can have side effects. 3.It has to be used judiciously under docctor's prescripti...
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My son has suffer from a fever from 18th July to till now. My son is 4 year old. His body temperature is between 100-103 celsius. But we consult with our family Dr. On 19th July morning. He has given some medicine 1. P250; 2. Chloroquine phosphate suspension 3.vomikind.but not improve till now, what shall I do now at first ? Dear Dr.

FIAP(NEONATE), MD - Paediatrics
Pediatrician, Ahmedabad
Chloroquine is specific for malaria so unless yoyears child is suffering from malaria it will not help. Your child might be having a simple viral infection which usually responds to paracetamol that you are giving to your child. However it is diff...
1 person found this helpful

Hello doctor, My father is diabetic. Now his diabetes PP figure is 250 (approx). He is suffering from Malaria vivax. We have completed 3 days course of chloroquine 250 mg with ziffy 200 and dolo 650. But only for one day it came down to 98.5 .after that is varying between 99.5 and 102. Please advise what to do next.

PG Dip Diet, B.Sc. - Dietitics / Nutrition
Dietitian/Nutritionist, Kolkata
Hello doctor,
My father is diabetic. Now his diabetes PP figure is 250 (approx). He is suffering from Malaria vivax. ...
You need to give him a balanced and easily digestible diet to support the action of medicines. His diet is not balanced that's why his body constituents are breaking down causing rise in blood sugar. Consult with a Dietician to know what to eat, h...
1 person found this helpful

Hi doctor, I am a mother to a 11 month old baby I have used lactare tablets for almost 5 months 5 tabs a day. Now I have over flow from last two menstrual cycles. I am using hydroxy chloroquine tablets from last 8 months my Dr. prescribed as a part of treatment for post natal arthritis Will polypharmacy and high dosage of medicine any thing to do with over bleed.

Erasmus Mundus Master in Adapted Physical Activity, MPT, BPTh/BPT
Physiotherapist, Chennai
Hi doctor, I am a mother to a 11 month old baby I have used lactare tablets for almost 5 months 5 tabs a day.
Now I h...
Not really as week before period you will not have any fluid discharge and also abdominal cramp might be due to menstrual cycles however this abdominal cramp is quite common in pregnancy women.

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Table of Content
About Chloroquine
When is Chloroquine prescribed?
What are the contraindications of Chloroquine ?
What are the side effects of Chloroquine ?
Key highlights of Chloroquine
What are the dosage instructions?
Where is the Chloroquine approved?
Medicines containing Chloroquine
How does medicine works?
What are the interactions for Chloroquine ?