Familial Glucocorticoid Deficiency is a medical condition that occurs when there is insufficient production of the glucocorticoid hormone by the adrenal glands. The signs and symptoms of this disease often start as early as childhood. Children develop low sugar levels due to this disease. Common symptoms in children are :
• Deep hyper pigmentation of the skin
• Pallor, sweating , palpitations and anxiety
• Abdominal symptoms
• Vision changes
• Seizures and Coma
• Mood changes
In newborn the symptoms are irritability, respiratory distress, seizures and apnea.
HOW IS FAMILIAL GLUCOCORTICOID DEFICIENCY DIAGNOSED?
The condition is usually diagnosed in the neonatal period. Based on the condition and regular blood glucose checks, the general physician may recommend adrenal imaging and histopathology for investigating the condition further.
HOW IS FAMILIAL GLUCOCORTICOID DEFICIENCY TREATED?
The treatment for this problem is rather intensive and exhausting starting with replacement therapy with oral hydrocortisone. Dose modification and check from time to time becomes mandatory to keep the problem in control.
DID YOU KNOW?
Overtreatment may result in poor linear growth, hypertension, edema, euphoria, insomnia, headache, steroid-induced acne,
hyperglycemia, Cushing syndrome, peptic ulcers, and cataract formation.