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Overview

Zolfresh 12.5 MG Tablet

Manufacturer :  Abbott India Ltd
Medicine Composition :  Zolpidem
Prescription vs OTC : Prescription by Doctor required

About Zolfresh 12.5 MG Tablet

Zolfresh 12.5 MG Tablet acts as a sedative and employed as a short-term treatment of insomnia. The drug is even known as a hypnotic. It acts on imbalanced chemicals of the brain in patients who suffer from insomnia, that is, problems with sleep.

Zolfresh 12.5 MG Tablet can result in an allergic reaction, thus the drug should be immediately stopped and medical aid should be sought in case you experience any symptoms like problems with breathing, hives, and inflammation of the throat, face or lips.

Avoid sharing the drug with anyone else. This is primarily because the dosage prescribed varies for both male and female. The drug is not meant for children. If you are prescribed Zolfresh 12.5 MG Tablet by your doctor, take it exactly as per his directions.

When considering the side effects of the drug, the most common are dizziness and a feeling of drowsiness. You may also experience nausea, anxiety, myalgia and hallucinations. Some major side effects of Zolfresh 12.5 MG Tablet are confusion, onset of depression, irregular heartbeat, mood swings and skin rashes.

If you experience any of the serious side effects or your symptoms persist for a long period of time it is best that you get in touch with your doctor. Any misuse or overdosage of Zolfresh 12.5 MG Tablet can result in serious consequences. The drug should not be taken if you have had alcohol before bed or during the daytime.

In the treatment for insomnia the initial dosage that may be prescribed for men is 10 mg and 5 mg in case of women. The dosage may then be increased accordingly as per the reaction of the body to the drug. The drug is generally not prescribed for a long period of time.

This medicine should be used only after the evaluation of potential causes of sleep disturbance. Failure of sleep disturbance to resolve after 7-10 days may indicate psychiatric or medical illness. Use with caution in patients with depression. Behavioural changes have been associated with sedative-hypnotics.

Zolfresh 12.5 MG Tablet causes CNS depression, which may impair physical and mental capabilities. Effects with other sedative drugs or ethanol may be potentiated. Closely monitor elderly or debilitated patients for impaired cognitive or motor performance; not recommended for use in children <18 years of age. Avoid use in patients with sleep apnea or a history of sedative-hypnotic abuse.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Somnologist before using this medicine.

    What are the uses of Zolfresh 12.5 MG Tablet

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Somnologist before using this medicine.

    What are the contraindications of Zolfresh 12.5 MG Tablet ?

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Somnologist before using this medicine.

    What are the side effects of Zolfresh 12.5 MG Tablet ?

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Somnologist before using this medicine.

    Key highlights of Zolfresh 12.5 MG Tablet

    • How long is the duration of effect?

      The effect of this medicine lasts for an average duration of 7 to 8 hours.

    • What is the onset of action?

      The effect of this medicine can be observed in 1.6 hours for an immediate release tablet and 1.5 hours for an extended release table.

    • Are there any pregnancy warnings?

      This medicine is not recommended for pregnant women unless necessary. It may cause respiratory depression in the neonates. The benefits and risks should be discussed with the doctor before taking this medicine.

    • Is it habit forming?

      Habit forming tendency has been reported

    • Are there any breast-feeding warnings?

      This medicine is known to excreted in breast milk. It is used in pregnant women only if necessary. Monitoring of excessive sleep, weakness and others changes in the behavior is necessary.

    • Does this affect kidney function?

      Limited information is available regarding the use of this medicine in patients with kidney disease. Kindly consult your doctor before taking this medicine.

    • Does this affect liver function?

      Caution must be taken in patients with hepatic impairment. Adjustment of dose is needed. Kindly consult your doctor before taking it.

    • Is It safe with alcohol?

      Consumption of alcohol must be avoided as it may cause additive effect on the CNS of the patient.

    • Is it safe to drive while on this medicine?

      Patient must avoid driving while taking this medicine as it may cause dizziness or drowsiness.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Somnologist before using this medicine.

    What are the substitutes for Zolfresh 12.5 MG Tablet ?

    Below is the list of medicines, which have the same composition, strength and form as Zolfresh 12.5 MG Tablet , and hence can be used as its substitute.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Somnologist before using this medicine.

    What are the dosage instructions?

    • Missed Dose instructions

      If you miss a dose of Zolfresh 12.5 MG Tablet, take the missed dose as soon as you remember. If it’s almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

    • Are there any overdose instructions?

      Seek emergency medical treatment or contact the doctor in case of an overdose.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Somnologist before using this medicine.

    Where is the Zolfresh 12.5 MG Tablet approved?

    • India

    • United States

    • Japan

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Somnologist before using this medicine.

    How does this medication work?

    Zolfresh 12.5 MG Tablet belongs to sedative and hypnotics. It works by blocking omega-1 type GABA receptors, results in increased chloride conduction and causes hyperpolarization. This effect will inhibit the action potential and decreases the excitability of cells and causes sleep.

      Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Somnologist before using this medicine.

      What are the interactions of Zolfresh 12.5 MG Tablet ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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      • Interaction with Alcohol

        Consumption of alcohol with this medicine is not recommended as it increases the risk of side effects like dizziness, difficulty in concentration. Do not perform activities that require mental alertness like driving or operating machinery.
      • Interaction with Lab Test

        Respiratory, cardiac and mental status must be regularly monitored.
      • Interaction with Medicine

        Opoids

        Opioids like morphine, codeine, tramadol, hydrocodone or any cough preparations containing these medicines should be avoided when you are on Zolfresh 12.5 MG Tablet or other benzodiazepines. Appropriate dose adjustments are to be made if coadministration is needed and monitoring of sedation, breathlessness, and blood pressure is necessary.

        Antihypertensives

        You may experience hypotensive effects like dizziness, lightheadedness if these medicines are used together. Regular monitoring of blood pressure is necessary. Appropriate dose adjustments or replacement of the medicine should be made under the doctor's supervision.

        Others

        Zolfresh 12.5 MG Tablet has negative interactions with the following medicines- Rifampin, Phenytoin, Ritonavir, Nelfinavir, Isoniazid, Nevirapine.

      • Interaction with Food

        It is generally advised to take Zolfresh 12.5 MG Tablet after food. However the medicine has no negative interaction with food. It may be consumed with or without food.

      • Interaction with Disease

        Zolfresh 12.5 MG Tablet has negative interactions with the following diseases- Depression, Severe liver aliments, Obstructive sleep apnea, Myasthenia gravis, Pulmonary disease.

      FAQs about Zolfresh 12.5 MG Tablet

      • Ques : Does Zolfresh 12.5 MG Tablet make you high?

        Ans : This drug produces a calming effect on the brain and induces sleep. While using this drug for a longer time, Zolfresh 12.5 MG Tablet may also make an individual dependent such that they are not able to sleep or function normally without taking it.

      • Ques : Does Zolfresh 12.5 MG Tablet have paracetamol (acetaminophen) or aspirin in it?

        Ans : No, this drug does not have paracetamol (acetaminophen) or aspirin in it.

      • Ques : Can I take Zolfresh 12.5 MG Tablet with prednisone?

        Ans : No drug-drug interactions have been found Zolfresh 12.5 MG Tablet taken with prednisone. However, always consult with your doctor before taking these medicines together.

      • Ques : Does Zolfresh 12.5 MG Tablet help with anxiety?

        Ans : This drug is used to treat insomnia, which may help ease anxiety in some patients. Remember, doctors do not prescribe this drug for anxiety alone because it does not work in the same manner as other sedatives anti-anxiety drugs.

      • Ques : What are the symptoms of an overdose of Zolfresh 12.5 MG Tablet?

        Ans : Symptoms include drowsiness, confusion, problems with coordination, floppy muscles, slow or difficult breathing, and even coma (loss of consciousness for a period of time).

      • Ques : What should I avoid when taking Zolfresh 12.5 MG Tablet?

        Ans : This drug can make you drowsy during the daytime and also decrease your mental alertness. You should not drive or operate heavy machinery until and unless you know how this drug affects you. Do not drink alcohol while you are taking this medication. Alcohol can make the side effects of Zolfresh 12.5 MG Tablet even worse.

      • Ques : Who should not take Zolfresh 12.5 MG Tablet?

        Ans : You should not take this medication if you are allergic to it or any of its ingredients. You should also avoid this drug if you have a history of depression, mental illness, or suicidal thoughts.

      • Ques : Can I take Zolfresh 12.5 MG Tablet with food?

        Ans : No, do not take Zolfresh 12.5 MG Tablet with or shortly after a heavy, high-fat meal. This medication may not work well if it is taken with high-fat foods.

      • Ques : Can Zolfresh 12.5 MG Tablet be taken every day? How long should it be taken?

        Ans : This drug should be taken exactly as prescribed by the doctor. The dose and duration of treatment should not be exceeded else it may lead to addiction towards Zolfresh 12.5 MG Tablet.

      • Ques : Does Zolfresh 12.5 MG Tablet cause dry mouth and affect weight?

        Ans : Yes, dry mouth is a common side effect of this drug. If you experience weight gain, it could be due to increased appetite.

      • Ques : How long does Zolfresh 12.5 MG Tablet take to start working?

        Ans : It starts working as soon as you take it and may make you very sleepy. You may remain sleepy for some time after you take the medication.

      • Ques : What are the withdrawal symptoms of Zolfresh 12.5 MG Tablet?

        Ans : Symptoms include unpleasant feelings, stomach and muscle cramps, vomiting, sweating, shakiness, and rarely, seizures.

      • Ques : How can I improve my sleep without medicines?

        Ans : Avoid consuming caffeine and nicotine, especially late in the day. Avoid exercise during the four hours before bedtime; daily exercise is beneficial to sleep but can interfere if done close to bedtime. Also, avoid large meals in the evening and naps.

      • Ques : What is insomnia?

        Ans : Insomnia is a common sleep disorder. A person suffering from insomnia may experience trouble in falling asleep, staying asleep, or both. As a result, they may get too little sleep or have poor-quality sleep, and they may not feel refreshed after waking up.

      • Ques : What are the causes of insomnia?

        Ans : Insomnia can be triggered by life-style changes including long-lasting stress and emotional upset. It can be caused due to various reasons such as certain medical conditions (depression, anxiety, post-traumatic stress disorder, Alzheimer's disease, and Parkinson's disease), medicines, sleep disorders, and substances (caffeine and other stimulants, tobacco and other nicotine products, and alcohol).

      References

      • Zolpidem-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 7 June 2022].Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/zolpidem

      • Zolpidem-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 7 June 2022].Available from:

        https://go.drugbank.com/drugs/DB00425

      • ZOLPIDEM tablet,solution-DailyMed [Internet].dailymed.nlm.nih.gov 2022 [Cited 7 June 2022].Available from:

        https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=ZOLPIDEM

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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