Formation of blood clots in the arteries of the lungs, heart or legs can actually kill a person. In such a case, the immediate medical action is necessary and the only way to deal with blood clots is thrombolysis.
Thrombolysis or thrombolytic therapy is a medical process that dissolves blood clots and facilitates blood flow to all parts of the body. Thus, it protects tissues and muscles from damage.

What are the causes of blood clots in the body?

  Poor blood circulation
  Conditions such as Deep Venous Thrombosis and atrial fibrillation
  Blood clots can also be formed because of dialysis catheters and by-pass grafts

How can you tell if you have blood clots?

  Swelling in one or more legs
  Cramp and tenderness in the legs
  Breathing trouble might indicate that blood clots have travelled to the lungs
  Sweating and frequent chest pain may suggest that blood clots have travelled to the heart

How is Thrombolysis performed?

Thrombolytic drugs are injected into the body intravenously. They make their way to where the blood clots exist and dissolve them. If there is a medical emergency, the drugs are delivered to the exact location of the blood clots and immediately start dissolving them. Another method is inserting a device into the blood clot infested region to break the clots up. The drugs which on entering the body dissolve blood clots are called thrombolytics. There are many varieties of thrombolytics such as the following-

  Streptokinase - It is a kind of enzyme. It is used when a person has just suffered a heart attack or pulmonary embolism. Doctors do not usually prescribe the second usage of this drug. It is injected into a vein and can be administered to pregnant women.

  Tenecteplase - Also an enzyme, it is a plasminogen activator. When it binds to the surface of the blood clot, it makes the clot degenerate.

  Reteplase - It is actually extracted from E-Coli. It is a sterile intravenous bolus injection

The leading cause of heart attacks and ischemic heart disorder is the formation of blood clots in the arteries that connect the heart and the brain. Thrombolysis is often employed as an emergency treatment for this purpose. Thrombolysis is also effective against blood clots formed in the lungs (which lead to acute pulmonary embolism). Sometimes blood clots are formed in the legs, upper extremities of the body, the pelvic region (deep vein thrombosis). These clots may travel to the lungs and heart.

Consult your doctor before undergoing the treatment.

Thrombolysis - Causes, Symptoms & Treatment Of It!

Varicose veins are enlarged and gnarly veins and they commonly appear in the feet and legs. They occur when veins get filled with blood and they are often red or bluish purple in color.

The main cause of varicose veins is the when the vein dysfunctions. Veins have valves in them that are supposed to keep the blood flowing forward, but if they fail to do so, blood in the vein starts to collect rather than continue towards the heart. Since the legs are furthest from the heart, varicose veins mostly affect the legs. Gravity, too, is a contributing factor as it makes it hard for the blood to flow up the vein.
Out of all the treatments available for varicose veins, sclerotherapy is the most effective.

What is sclerotherapy?
Sclerotherapy is a form of injection therapy that is designed to improve the way the varicose veins appear on your legs.

The Procedure
During the procedure, a solution called sclerosant is injected in the veins that scars and destroys the vein's internal lining which causes the blood to clot. After the solution is injected, pressure over the veins is applied to prevent the return of the blood as you stand up. Compression stockings are worn for maintaining the pressure.

After the Procedure
There is no prolonged recovery time for sclerotherapy. You can move around immediately after the procedure, but do not strain yourself too much. However, bed rest is not recommended as it might stress the vein. You probably have to keep wearing the compression stockings for a few days more.

Reasons for Choosing Sclerotherapy
Sclerotherapy is best for treating the following problems-
1. Small veins and spider veins that do not cause severe damages
2. Smaller varicose veins that might return even after vein stripping surgery (the surgical removal of the superficial saphenous vein with minimal incisions to treat varicose veins).
3. Larger varicose veins
4. Follow up to any other surgery to treat varicose veins

Risks involved
Sclerotherapy, like any other treatment, has certain risks. The risks include-
1. Skin discoloration
2. The varicose veins can still return after the treatment
3. Bruising, itching, blistering and pain in the treated area
4. Mild or severe allergic reaction to the solution (sclerosant) used
5. Blood clots in the deep vein system.

Varicose Veins: Using Sclerotherapy to Get Rid of It

Your heart is the most important and vital organ of all and regulates the flow of heart to all parts of the body. Thus, the valves and the arteries which take the blood to your heart are also an important component in ensuring that the circulation is constant. Thus, any hindrance to this process will put a lot of pressure on your heart and lead to more serious problems in the long run. Coronary artery disease is one such problem and can seriously put the health of your heart at risk.

What is coronary heart disease?
Coronary arteries are very important blood vessels, which carry nutrients, blood and oxygen to your heart. If the level of bad cholesterol is high in your blood, it will start leaving deposits on the walls of the arteries which are commonly known as plaque. This plaque will start building up over time causing blockage of the arteries and disrupting proper blood flow. Excessive build up of the plaque may then rupture the lining of the plaque. This will then induce blood clotting and further prevent the normal flow of blood.

Symptoms
Primary symptoms may include

Shortness of breath: This may occur while you are exercising or performing activities which are mildly exerting.
Heart beats very hard and fast: Your heart may beat very hard and fast, especially when doing everyday activities such as climbing stairs or walking for a prolonged distance.
Angina or chest pain: You may experience pain in your chest as if someone was pressing against it with a lot of force. Angina is also triggered due to stressful activities or even emotional stress. It usually occurs on the left or the middle of the chest and may even be felt in the back, arms, and neck.
Heart attack: Heart attacks are the most common and the most serious complications of coronary heart disease. You would feel extreme pain, akin to crushing on your chest, shoulder, or arm. It may even be accompanied by jaw pain, and sweatiness.
Treatment
Non invasive forms of treatment are always preferable rather than invasive surgeries or procedures to treat coronary heart disease, especially where the risk of serious complications such as heart attack are still on the lower side. Some of the treatments used for coronary heart disease are as follows:

Making lifestyle changes: Quit smoking, reduce alcohol consumption along with consumption of regulated diet will automatically start cleaning plaque that has built up within the arteries. Losing weight also tends to help.
Medications: Special medications can take care of cases wherein the deposits are still lesser and the plaque buildup can be removed without the requirement of extensive surgery. Anti-cholesterol medications are one example of this.
Surgical procedures: These are usually employed when the blockage is severe and cannot be corrected by the conventional methods mentioned above. Some of the procedures are angioplasty, stent replacement, as well as coronary artery bypass surgery.

Coronary Artery Disease -  Know the Primary Signs!

An unhealthy diet is an absolute no in daily life to remain healthy, fit and without any disease. Unhealthy diets fail to give the body the correct amounts and varieties of proteins and nutrients for a maximum proper health.
Too many intakes of calories lead to an unhealthy diet, which also increases blood pressure. It leads to a very poor calorie ratio-to-nutrient that leads to gain weight and also leads to malnutrition along with various health problems. Unhealthy diets cause chronic disease, hypertension, cancer, diabetes, osteoporosis and cardiovascular disease.
Therefore, unhealthy eating habits should be avoided and strongly abandoned.

Why Avoid Unhealthy Diet?

It causes obesity. Increased intake of nutrient-dense foods like fruits, sugar, processed carbohydrates and animal fat leads to obesity.
Nutrient deficiency is another harmful effect of following an unhealthy diet.
Illness is another factor. Poor intake of nutrition leads to diseases like heart disease, diabetes, and cancer. Lack of calcium weakens the bones, lack of vitamin A and C suppress the body immune system leaving a person vulnerable to diseases.
Increases the risk of coronary artery disease as unhealthy diet contributes to building up of plaque in the coronary arteries which can cause heart attacks.
Coronary Heart Disease - A Serious Issue!
It is a disease which leads to plaque building inside the coronary arteries, which supply rich oxygen blood to the human heart muscle. Over time the plaques either hardened or get ruptured and hardened plaque restricts the coronary arteries, which reduce the oxygen flow to the heart. On the other hand, if the plaque is ruptured blood is formed on its surface which also narrows the coronary artery and restricts the blood flow. And if the blood flow is blocked or reduced, then it might lead to Angina and heart attacks leading to loss of life. Angina causes chest pain it can also cause pain in the neck, back or arms. It is a state where one gets a feeling of indigestion.

Outlook
Changes in lifestyle, eating habits, intake of medicines and its procedures helps to prevent this disease. These steps can also reduce the chances of health problems. Therefore, a proper healthy diet is a must in a person s routine because it serves as one of the links to coronary heart diseases. In order to live long, live healthily and live happily one needs to adopt a good eating habit, take care of the medicines they intake, certain input time of exercise, change the monotonous lifestyle to lessen down the chances of their occurrence. Adopting healthy food habits also enables the body to fight against diseases and infections, reducing the rate of illness. It also reduces stress and provides a good healthy and happy life.

Unhealthy Diet - How It Is Related With Coronory Heart Disease?

Dialysis is a very important and life-saving procedure. It is performed to replace kidney function in case of renal failure. Wastes and extra fluids in the blood are filtered out during this process. To be able to perform Dialysis, the connection between the patient s bloodstream and the equipment for performing Dialysis (dialyzer) outside the body is established. This connection is created through Dialysis Access Surgery. It is a type of Vascular Surgery which forms the vascular opening for access during Dialysis. Thus, Dialysis Access Surgery is the lifeline for the survival of the patient.

Types of Vascular Access for Dialysis- 
There are three types of Vascular Access for Dialysis: Arteriovenous (AV) Fistula, Arteriovenous (AV) Graft, and Venous Catheter.

  Arteriovenous (AV) fistula is a surgical connection of an artery to a vein. An AV fistula is usually placed in the upper arm or in the forearm. It causes extra blood to flow into vein making it grow large. A larger vein hence provides easy access to blood vessels. An AV fistula is preferred over other methods as it lasts longer than other methods of access and provides a good flow of blood. Moreover, it is less prone to infection and blood clots than other methods. Before an AV Surgery, a Vessel Mapping Test is sometimes performed for assessing the blood vessels most suitable for Dialysis. An AV fistula is performed under local anaesthesia and requires two to three months for maturation before hemodialysis. If it fails to mature, the procedure is repeated.

  Arteriovenous (AV) graft is performed when AV fistula fails to mature. It is hence the second most preferred choice for long-lasting access to vascular tissues for Dialysis. An AV graft is a looped plastic tube which establishes a connection between an artery and a vein. Like AV fistula, AV graft is also performed under local anaesthesia. It is slightly more difficult to maintain than an AV fistula.

  A venous catheter is used for short- term hemodialysis. It is a tube which is inserted into chest, neck, leg, or near groin for vascular access. After exiting the body, the tube splits into two halves. In the case where a renal disease has made quick progression leaving little or no time for the AV fistula or AV graft to mature, a venous catheter is used to establish the required vascular connection. This procedure is also performed under local anaesthesia. It is a tool for emergencies but is not suited for long- term use. It can cause narrow vein due to an infection,
scarring, or blood clot. If long- term venous catheter is used, it is tunnelled under the skin which has fewer problems associated with it and is more comfortable. 

How to Care for a Vascular Access?
  Get checked for infections and other problems before each hemodialysis session;
  Use the operated site for access only for the intended use;
  Always keep the access clean;
  Prevent cutting or bumping the access;
  Check for thrill/ vibration in the access and inform the doctor if any;
  Do not put pressure on the access site;
  Do not put blood pressure cuff around the access arm;
  Do not wear jewellery or tight-fitting garments over the site;
  Do not lift a weight.

Take Away-
Vascular Surgery for Dialysis is performed to provide vascular access for the procedure. AV fistula is the most preferred type followed by an AV graft. A venous catheter is recommended to be used only in case of an emergency when there is not much time left for the other two options to mature.

Vascular Surgery - Can It Help For Dialysis?

Blood flows through the tubes called as blood vessels. There are two networks of blood vessels   the arteries and the veins. The arteries carry pure or oxygenated blood from the heart to the various parts of the body. The veins, on the other hand, collect impure blood from all over the body and reach it to the heart. Blood flow in the veins is controlled via valves, which ensure blood does not flow in the reverse direction (against its desired direction of flow). The veins in the legs, which are farther from the heart, are quite thick and exert extra pressure to pump blood into the heart. They need to transport blood against gravity and so in people who are prone to stand for long hours, they can become thicker, swollen, twisted, and engorged. In severe cases, there could even lead to bleeding.

Some common causes for varicose veins are:

Damaged valves which are not able to control the flow of blood in the required direction.
Veins with a thin wall that are unable to control blood flow.
Risk factors: Though these are the suspected causes, there are specific risk factors which aggravate the condition of varicose veins.

Family history
Smoking
Occupations which require prolonged standing (construction jobs, painters, etc.)
Pregnancy
Obesity
Age, which reduces the elasticity of the veins
Surgery in the leg, which could have hampered the values or veins
There are quite a few symptoms of varicose veins. These are quite distinct and present as:

Swollen, ropy leg veins which can be blue
Pain, especially with prolonged standing
Tenderness on touching the veins
Itching and heaviness along the veins
Skin changes like scaling and dryness
Night cramps around the area
Susceptibility to bleed from these veins
While varicose veins are easy to diagnose given their distinct clinical presentation, some additional testing can involve the following:

Doppler ultrasound
Scanning
MRI
As said, prevention is better than cure; here are some preventive measures that can be really helpful:

Elevate legs as much as possible. When working, take short breaks to reduce stagnation and promote blood circulation
Quit smoking
Avoiding alcohol, as it causes venous dilation
Weight management
Avoid tight clothing and sitting with cross-legs for prolonged periods as they put a lot of pressure on the veins and valves
Follow a regular exercise regimen to improve blood flow in the legs, like walking or running
Starting from the least invasive to the most, this condition can be treated by:

Compression stocking (Ted hose or Jobst stocking) which improves circulation and reducing pain
Surgical options include sclerotherapy, laser treatment, and stripping off the vein. These are done in very severe cases, but quite rare.

Varicose Veins - How Best It Can Diagnosed?

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