Renal Tubular Acidosis is a medical condition. When the kidney is unable to acidify urine, it leads to the accumulation of acid in the body. Usually, when blood is filtered by the kidney, it passes through the tubules of the nephrons (the functional unit of the kidney).

Before it flows into the bladder from the kidney, the urine undergoes an exchange of salts, acids and other solutes. Renal tubular acidosis results in the formation of excessive amounts of acid because the kidneys cannot drain them. This may happen because the kidneys cannot reabsorb the alkaline bicarbonate ions from the urine in the early segment of the nephron or because of inadequate production of acidic hydrogen ions in the latter half of the nephron.

Renal Tubular Acidosis is simply associated with abnormal urinary acidification. Other functions of the kidneys remain unimpaired.
There are several different types of renal tubular acidosis-

  Distal Renal Tubular Acidosis (RTA)
This is the most fundamental form of RTA. It is characterized when the hydrogen ions are not secreted into the lumen of the nephron by the alpha-intercalated cells of the medullary collective duct of the distal nephron. When this happens the pH of urine cannot be brought down below 5.3. Renal excretion is inhibited and hydrogen ions are not eliminated which leads to academia. At the same time, Potassium ions cannot be absorbed by the cell which leads to hypokalemia. The end result is protein retention and potassium excretion. Distal RTA can lead to the urinary stone formation, calcium deposits in the kidney, rickets and osteomalacia and Sjogren s syndrome.

  Proximal RTA
When proximal tubular cells reabsorb 85% of filtered bicarbonates and 60% of filtered sodium from the urine, then this again leads to academia. The distal intercalated cells, however, function normally and so the academia is not as severe as in case of Distal RTA. The alpha-intercalated cells can acidify urine to a pH of 5.3 or less because they produce hydrogen ions. Proximal RTA is also associated with Fanconi Syndrome which is characterized by aminoaciduria, uricosuria, glucosuria, and tubular proteinuria.

  Combined distal and proximal RTA
Inherited carbonic anhydrase II deficit leads to combined distal and proximal RTA. This is accompanied by osteopetrosis, cerebral calcification, and renal tubular acidosis. Cases of combined distal and proximal RTA are very rare.

How is RTA understood?
The following steps are applied to analyze Renal Tubular Acidosis-
  Determining the anion gap in acidosis. The normal Anion Gap is 8-12 (4-6 mEq/L)
  Separating the renal from the extrarenal causes of normal anion gap acidosis
  Classifying the types of RTA
  If it is distal RTA, further tests will be necessary to support the diagnosis

How is RTA diagnosed?
Three types of tests can reveal if a person is affected by Renal Tubular Acidosis-
  Urine test
  Acid load test
  Physical examination

Treatment of RTA-
Doctors prescribe either or both of the following two types of therapies-

  Alkali therapy- The pH level of urine is restored and electrolytes are balanced
  Vitamin D supplements- If RTA leads to bone deformities or rickets, your doctor will prescribe vitamin supplements to strengthen your bones.

Timely diagnosis can prevent the effects of Renal tubular Acidosis from becoming compounded. With the right medication, a person can lead a healthy normal life.

What Should You Know About Renal Tubular Acidosis?

The three primary functions of the kidney are- eliminating waste materials and toxins from the body, producing hormones that help control your body mechanism and regulating blood pressure. Chronic Renal Failure, also known as Chronic Kidney Disease, refers to the condition where your kidney gradually stops functioning properly over time- weeks, months or years. As the condition worsens, wastes and fluids start to build up in your system instead of being filtered out. This leads to an end-stage renal failure/disease.

What causes Chronic Renal Failure?
Chronic renal failure is caused due to a condition or disease that impairs kidney function. The most common causes are- diabetes (Type 1 and Type 2), polycystic kidney disease, glomerulonephritis, interstitial nephritis. Glomerulonephritis occurs when the filtering units of the kidney become, inflamed. Interstitial nephritis refers to an inflammation in the kidney tubules and its surrounding regions. Prolonged obstruction of the urinary tract due to kidney stones or enlarged prostate, also can cause chronic renal failure.

What are the symptoms that you must watch out for?
Symptoms and signs of chronic renal failure develop gradually over time. Therefore, most of the time people suffering from this condition are diagnosed at the later stage when functioning of the kidney is significantly impaired. Nevertheless, if you encounter signs such as unintentional weight loss, weakness and fatigue, vomiting and nausea, swelling of face and legs, cramps and muscle twitches, change in the urinating pattern, easy bruising, blood in the stools etc., then you should see a doctor and have yourself diagnosed. In case the fluids get accumulated in the lining of your heart or lungs, you may experience chest pain and shortness of breath.

Role of homeopathy in curing Chronic Renal Failure-
Unlike conventional treatment methods which focus on the pathological condition, homeopathy takes a holistic approach to treat the individual. Homeopathy remedies and medicines are natural, and try to rectify the underlying causes of this condition. The medications are selected and prescribed after thorough analysis of the patient s medical history and health condition. A particular remedy is chosen keeping in mind the general symptoms of the condition. Among several homeopathic medicines, the frequently used ones are- Belladonna and a solution made from gold and sodium. Homeopathy remedies reduce swelling of the face, cures kidney inflammations, and reduce severe, recurring pain in the lumbar region. They work by stimulating your immune system so that the damaged kidney and other organs start functioning more correctly.

Homeopathy remedies do not provide substitutes for any organ of your body. They simply repair the damaged organs, improve your overall health and thereby prevent the person from suffering a relapse.

Chronic Renal Failure - How Homeopathic Treatment Is Best For You?

Ever heard of that phrase  I can taste bile at the back of my mouth ? It is generally used to express disgust. However, in medical parlance,  bile , the English synonym for disgust, plays an important role in the digestive system. It helps in the digestion of fats (breaks the fats down to smaller particles) and contains the waste products of the blood. Bile is secreted from the gallbladder which is a small organ (sac-shaped) present below the liver.

Gallbladder surgery is carried out to treat gallbladder related problems such as gallbladder stones. Presence of gallstones in the gallbladder can hamper bile production. The symptoms that you may experience include feeling unwell and fatigued, the color of the skin turning yellow and an intense tummy ache. The first method of treatment for gallstones is to dissolve them with the help of natural means. However, if this does not work, then gallbladder surgery is done.

Pre-surgery
A pre-surgery assessment is carried out by the doctor a few weeks prior to the surgery. A general health check and blood tests are carried out to determine the procedure of the surgery. Your concerns regarding the surgery are addressed by the doctor; he/she also advises you on how to prepare for your surgery.
Procedure

Gallbladder surgery can be performed in two ways; an open surgery or a laparoscopic surgery. The type of surgery you will undergo will depend on your tests.

Laparoscopic surgery: In this procedure, an incision is made on the belly button (naval region). Following this, two or three other incisions are made on the right side of the stomach. Carbon dioxide is then pumped into the stomach to make the abdomen inflated and a laparoscope is then inserted to see the insides of the abdomen. Through the other incisions, surgical instruments are inserted to remove the gallbladder. Once the removal procedure is completed, the carbon dioxide is pumped out and the incisions are closed.
Open surgery: In an open surgery, a larger incision (as compared to laparoscopic surgery) is made in the abdomen, right below the ribs. The gallbladder is removed using surgical instruments and then the incision is closed.
Post-surgery: In case of laparoscopic surgery, the recovery period is shorter; around two weeks. An open surgery, on the other hand, requires a longer recovery period of 6-8 weeks. You can live a normal life without the gallbladder, as the bile will then directly travel to the digestive system. Mild symptoms of diarrhea and bloating may be experienced. However, they should be temporary and subside within a few days.

Gall Bladder Problems - Which Surgical Procedure Can Help?

Medical science constantly challenges the boundaries by finding not only the cures to the most dangerous diseases, but finds a way to prevent them even before they occur. With years of research, practice and data available for analysis, scientists are using advanced technology in combination with years of research to create a predicting mechanism for often fatal diseases like cancer.

Breast cancer screening has always been done with mammography. The fact is that this method is only 75% accurate, laden with false positives and misses a whole set of women totally- and that too when cancer has already developed. Part of the problem comes from the dense breast tissue which one in three women have. This tissue masks the lumps, which makes it difficult for mammograms to accurately screen cancer.

Some breakthrough scientific methods are changing this by drawing on years of research to predict this deadly disease, years before it can manifest itself.

A genetic test to predict cancer 10-11 years ahead of time
This test was performed to see how environmental factors could influence cancer, along with habits like smoking, abusing alcohol or hormones, genetic changes that occur and are put a large percentage of the women at a high risk of developing this disease.

A simple blood test is used for the genetic analysis of hereditary cancer. Researchers found a biological marker, methylation of the ATM gene, which has a very high ability to predict the risk of developing cancer, several years before diagnosis. 'Methylation' concluded that when one biological indicator is exposed to carcinogenic substances, or other abusive substances like tobacco and alcohol, it may trigger the development of cancer. On the flip side, this test will take time to reach the commercial market and even then cannot give an exact timeline as to when someone may develop the disease.

A simple blood test to predict breast cancer 5 years before it develops
This is the kind of medical miracle the world is looking for. Last year in April, researches in Denmark identified a simple blood test that can predict breast cancer five years before it actually develops with an accuracy of a whopping 80%.

It works by "measuring all of the compounds in the blood to build a 'metabolic profile' of an individual, in order to detect changes in the way chemicals are processed, during a pre-cancerous stage," says Laura Donnelly, health editor at The Telegraph, which covered this development. Danish researchers observed 57,000 participants over 20 years, gathering blood samples along the way, specifically comparing a set of 800 women who remained healthy or developed breast cancer within 7 years of their first blood sample. The researchers found they were able to predict, with 80 percent accuracy, which patients would be affected by the disease, just by looking at the metabolic profiles they built from the participants' blood samples. The results have been published in Metabolomics.


Are you living with the uncertainty of a lump in your breast? It's time you take the first step and consult a specialist here.

Can Breast Cancer Be Predicted Before It Develops?

Menorrhagia refers to very heavy and prolonged menstrual bleeding or periods in women. The bleeding is abnormal in nature, and if this continues for a long time, a hysterectomy surgery needs to be carried out to solve the problem.

Bleeding during the night time and passage of large blood clots during menstruation are other symptoms of Menorrhagia.

Causes:

The various possible causes of this kind of heavy menstrual bleeding are:

Hormonal imbalance, specifically of estrogen and progesterone is a common cause, which is more likely in adolescents and in women nearing menopause. Dysfunction in the ovaries also causes hormonal imbalance.

Non-cancerous tumors or fibroids may also be responsible for menorrhagia.

Women suffering from a miscarriage or ectopic pregnancy are likely to experience heavy menstrual bleeding.

Using blood thinners may lead to menorrhagia.

An intrauterine device used for birth control measures can cause disturbance and may lead to heavy menstruation.

A condition known as adenomyosis, where the glands in the uterus lining get embedded in the walls of the uterus, also causes menorrhagia.

Pelvic inflammatory diseases, infection in the uterus or fallopian tubes are other common causes.

Heavy bleeding may occur in patients with ovarian or cervical cancer.

Diseases of the kidney, liver or thyroid diseases may also cause menorrhagia.

Diagnostic Tests:

Several tests and methods are carried out for the diagnosis of menorrhagia. They are:

A general physical examination.

Bleeding diary of the woman.

Blood tests to detect anemia or thyroid.

Pap Smear for the evaluation of cervical inflammation, infections or cancer

Ultrasound for evaluation of pelvic organs like uterus, ovaries and pelvis.

Hysteroscopy, where a camera is inserted into the uterus to observe the linings.

Sonohysterography, where a fluid gets instilled into the uterus along with an ultrasound test.

Treatment:

Certain drugs are used to treat menorrhagia. They include:

Iron supplements for treating anemia.

NSAIDS or non-steroidal anti-inflammatories for treating and reducing blood loss.

Tranexamic acid is used for reducing menstrual bleeding.

Several oral contraceptives are used for regulation of the menstrual cycle. Oral progesterone corrects hormonal imbalance and reduces bleeding.

Surgical procedures for treatment of menorrhagia include:

Hysteroscopy, dilation and curettage, where uterus lining is scraped and evaluated.

Uterine artery embolization treats menorrhagia with fibroids.

Focused ultrasound ablation enables the killing of the fibroid tissue.

Myomectomy, endometrial ablation and endometrial resection are other surgical techniques.

Hysterectomy surgery is the penultimate solution, where the uterus, cervix or ovaries are completely removed.

Menorrhagia is characterized by abnormally heavy menstrual bleeding in women. This is quite unhealthy and proper measures must be taken for curing the heavy bleeding.

Menorrhagia (Heavy Menstrual Periods) - A Common Indication For Hysterectomy

6 face washing mistakes that are damaging your skin, everyday!

Face-washing may be a simple everyday task that requires no great effort on your part. But when it?s not done right, it causes significant harm to your skin, each day. The mistakes that you may make while washing your face could lead to issues like irritation, dryness and even wrinkles. Read on to find out how you can avoid making these common errors, and save your skin from blemishes, ageing and lustreless look.

1. Using the wrong cleanser

The use of the wrong cleanser can throw your ph levels out of balance. The optimal ph balance of your skin is 5.5ph. This is the ideal level at which the thin protective layer on the surface of the skin (called acid mantle) can function to keep germs, toxins and bacteria at bay. You should therefore be picking your cleanser based on your skin type as it would come with the right ph balance. 

2. Not cleaning your hands before touching the face

Always clean the germs and dirt of your hands first before moving onto your face. Ignoring this crucial first step can cause you to transfer all the bacteria and dirt of your hands on your face, giving rise to common skin problems such as acne, pimples and blackheads.

3. Using a pre-used washcloth

To avoid the filth from clogging your pores, always clean the washcloth that you use with an antiseptic to keep germs and bacteria at bay. Once you're done washing your face, don't rub the cloth all over your face but pat dry it.

4. Washing face using with hot water

When it comes to the water that you splash on your face, you should always use lukewarm or room temperature water. This is because hot water leaves your skin dry as it washes away the skin's essential oils; and cold water can break the capillaries (fine blood vessels) of your skin. In contrast, mildly lukewarm water will keep your skin hydrated and healthy.

5. Not washing the face twice a day

Just as you shouldn't ignore this important skin care habit that keeps your skin clean, you also shouldn't go overboard with it. Excessive face-washing can hamper the natural oil production of your skin, giving rise to dryness and irritation as a result. Your skin requires the natural oil it produces to keep it smooth and supple. Ideally, you should wash your face twice daily - once in the morning for removing the bacteria and dirt that clogged your pores, and again at night before going to bed.

6. Rushing through the routine

Lastly, don't rush through your cleansing routine. Make sure to properly rinse your face of cleanser completely, otherwise the residues would cause your skin to dry up later on, leading to skin irritation.

It is therefore very important to pay attention to all the little details that make up your face-washing routine. By doing it right, you get to achieve the clear and blemish-free skin that you always wanted.

If you would like to consult with me privately, please click on consult.


6 Face Washing Mistakes that are Damaging Your Skin, Everyday!

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