Irrfan Khan's saddening revelation about his health and diagnosis of Neuroendocrine tumour (NET) has undoubtedly created a rage amongst his fans, which is now being followed by good wishes for speedy recovery from his supporters all across social media.  

The actor shared in an emotional Twitter post that he s been diagnosed with NET, a rare tumour that develops from cells of the neuroendocrine system and grows predominantly in the digestive or respiratory tract - lungs, appendix, small intestine, rectum, and pancreas - it can occur in any part of the body.

Here is more on Irrfan s disease:

What is NET?

A neuroendocrine tumor is characterized by a rapid and abnormal growth that happens in the nerve cells which produce hormones. Hormones control how different organs in the body work.

It is a condition wherein, endocrine cells, the hormone-producing cells of the body, develop a tumor in any part of the body - while it can can grow in lungs or the thymus, or more rarely, in the ovaries, kidneys, or testicles - the most common is lung, intestines, and pancreas.

What causes NET?

A neuroendocrine tumour is quite a rare disease, occurs in less than one per million cases. The exact cause is not known.

The Symptoms-

It can cause a myriad of symptoms, depending on where in the body the NET is.

If it is in your digestive system, it can cause pain or discomfort in the abdomen area that comes and goes. You may feel sick, nauseated, vomited, or there may be a change in how often you pass stools.
If the NET is in the lung, it can cause shortness of breath, chest infections, or you can even have a cough up blood.
Weight loss and loss of appetite may also be some common signs of a neuroendocrine tumour.
Some NETs may overproduce a hormone-like substance called serotonin. This causes a group of symptoms called carcinoid syndrome. Symptoms include wheezing (like asthma), flushing of the skin and diarrhoea.
Who can be affected with NET?

These tumours, depending on the type, are more common in certain age or sex. And few have very strong family history too.
People who have a rare condition called multiple endocrine neoplasia 1 have an increased risk of developing a NET.
Did You Know?

Apple founder  Steve Jobs  died from the same disease in 2011. The tumour affected his pancreas.

Know The Different Types of NET:

Based on the organ that is affected, NET can vary a lot. When the chromaffin cells that produce adrenaline are affected, it is called Pheochromocytoma, and it is related to the stress levels of the body.

When a cell is formed abnormally under the skin and the hair follicles, it is called Merkel cell cancer. This is also called neuroendocrine carcinoma of the skin and the condition can occur anywhere in the body. The commonly occurring places include lungs, gastrointestinal tract, and brain.

The status of the tumour, cancerous (malignant) or noncancerous (benign), decides the survival rate. Often slow-growing and noncancerous, they can invade surrounding parts of the body and at times, turn cancerous and spread across the body. However, you can still choose to live a good quality life with strict modifications in diet and lifestyle. The changes are made after taking into consideration the symptoms of the tumor. The organ where the tumor is formed also matters.

How Is It Treated?

Treatment depends on the location of the tumour, its type, how severe it is and whether it has spread to other parts of the body. Usually, the first treatment choice is surgery to remove the tumour. And, if the NET cannot be removed, your will prescribed with a treatment that will not only relieve the symptoms but will also improve the quality of your life.

How can a NET be prevented?

The first thing you need to do for the prevention of NET is to curb stress. Stress affects the entire body severely.

Lifestyle modifications:

A healthy lifestyle is what you need to stick to if you want to manage its symptoms during the treatment cycle. Your doctor will prescribe you to do exercises at least 4 days a week for a minimum of 30 minutes. You can also try a walk instead of strenuous exercises.

People with carcinoid syndrome may be advised to avoid food or activities that may trigger flushing, such as eating spicy food or drinking alcohol.

Indulge yourself in therapies that help in gaining more positive energy. If you are already affected by NET, eliminate all the sources of stress and get a good night's sleep every day. Join the support groups that make you grow strong and happy. After all, the mind is devised to do miracles when it is full of life and positive thoughts.

Is Irrfan Khan's tumour curable?

Dr Saumitra Rawat, HOD, Surgical Gastroenterology & Liver Transplant, Sri Ganga Ram Hospital, said, "NeuroEndocrine Tumour is an abnormal growth of Neuroendo cells which are present in bodies. When there is an abnormal growth, then it forms a tumor - Normally seen in intestine, pancreas, lung, thyroid and other parts of the body".

On commenting on Khan's case, he said, "It depends on the location of tumour, its size, and what is its mitotic index".

"Depending on where the tumour is localized, you can take it out surgically and the chances of cure are very high", Dr Rawat explained.

Actor Irrfan, who has been diagnosed with the disease is one of the most versatile actors in India, has also made a name for himself in the west, where he has been an important part of critically-acclaimed films such as  The Namesake ,  Jurassic World , and  Life of Pi . At home, the actor has delivered remarkable performances in films such as  Haasil ,  Paan Singh Tomar ,  Maqbool ,  Lunch Box ,  Piku , and the most recent  Hindi Medium .

Irrfan Khan is not just a disarmingly natural actor, but also an endearing human being -- honest and humble to the core. It s time to stand together and pray for him a speedy recovery!

Irrfan Khan - Battle Against Neuroendocrine Tumour!

Medical science constantly challenges the boundaries by finding not only the cures to the most dangerous diseases, but finds a way to prevent them even before they occur. With years of research, practice and data available for analysis, scientists are using advanced technology in combination with years of research to create a predicting mechanism for often fatal diseases like cancer.

Breast cancer screening has always been done with mammography. The fact is that this method is only 75% accurate, laden with false positives and misses a whole set of women totally- and that too when cancer has already developed. Part of the problem comes from the dense breast tissue which one in three women have. This tissue masks the lumps, which makes it difficult for mammograms to accurately screen cancer.

Some breakthrough scientific methods are changing this by drawing on years of research to predict this deadly disease, years before it can manifest itself.

A genetic test to predict cancer 10-11 years ahead of time
This test was performed to see how environmental factors could influence cancer, along with habits like smoking, abusing alcohol or hormones, genetic changes that occur and are put a large percentage of the women at a high risk of developing this disease.

A simple blood test is used for the genetic analysis of hereditary cancer. Researchers found a biological marker, methylation of the ATM gene, which has a very high ability to predict the risk of developing cancer, several years before diagnosis. 'Methylation' concluded that when one biological indicator is exposed to carcinogenic substances, or other abusive substances like tobacco and alcohol, it may trigger the development of cancer. On the flip side, this test will take time to reach the commercial market and even then cannot give an exact timeline as to when someone may develop the disease.

A simple blood test to predict breast cancer 5 years before it develops
This is the kind of medical miracle the world is looking for. Last year in April, researches in Denmark identified a simple blood test that can predict breast cancer five years before it actually develops with an accuracy of a whopping 80%.

It works by "measuring all of the compounds in the blood to build a 'metabolic profile' of an individual, in order to detect changes in the way chemicals are processed, during a pre-cancerous stage," says Laura Donnelly, health editor at The Telegraph, which covered this development. Danish researchers observed 57,000 participants over 20 years, gathering blood samples along the way, specifically comparing a set of 800 women who remained healthy or developed breast cancer within 7 years of their first blood sample. The researchers found they were able to predict, with 80 percent accuracy, which patients would be affected by the disease, just by looking at the metabolic profiles they built from the participants' blood samples. The results have been published in Metabolomics.


Are you living with the uncertainty of a lump in your breast? It's time you take the first step and consult a specialist here.

Can Breast Cancer Be Predicted Before It Develops?

Skin cancer is a condition with abnormal and cancerous skin growth. This often develops due to the over exposure of skin to the sun rays. The three main types of skin cancer include basal cell carcinoma, squamous cell carcinoma and melanoma. Skin cancer affects those areas of skin which remains sun-exposed, including ears, neck, chest, scalp, lips, face, hands, arm and legs. It can also develop on those areas of skin that are not exposed to sunlight like beneath toenails or fingernails, on palms and on genital area.

Here are some of the factors which increase your risks of getting skin cancer:

1.Fair complexion: Low levels of the pigment melanin in skin causes fair complexion. Fair- skinned individuals who have a history of hazel or blue eyes, repeated sunburns and people who have red or blond hair are highly susceptible to developing this form of cancer. Less pigment in skin makes an individual more vulnerable to skin damage from harmful UV radiation.
 
2. Excessive sun exposure: Exposure to the sun may lead to the development of skin cancer, if you don't protect your skin by sunscreen and clothing. Tanning beds and lamps may also increase the risk of developing this type of skin cancer.
                                            
3. High-altitude places: The exposure to sunlight is more intense in areas of high altitude and near the equator. Living at higher elevation also makes you more vulnerable to radiation because the sunlight is strongest there.

4. Moles: People with abnormal moles are at a higher risk of developing skin cancer. These moles are irregular in shape and are larger than normal moles.

5. Precancerous skin lesions: Your risk of developing skin cancer increases if you have skin lesion. These are scaly and rough patches that range from brown to dark pink in color. The most commonly affected areas are head, hands and face of fair-skinned people.

6. Weak immune system: Weak immune system caused by HIV or AIDS and immunosuppressant drugs that you take after an organ transplant may increase your risk of developing skin cancer.

Know If You Are At Risk Of Skin Cancer

World Cancer Day, organized by the Union for International Cancer Control (UICC) and celebrated each year on 4 February, is an opportunity to rally the international community to end the injustice of preventable suffering from cancer.
Cancer is one of the worst diseases, which kills millions of people across the world. While there is a wide range of treatment options available, the best way to deal with it is to ensure a good diet along with a healthy lifestyle. Here is a list of cancer-fighting food products, which can immensely help to prevent cancer.

Green vegetables: Leafy green vegetables have multiple health benefits. They are not only rich in minerals, vitamins, enzymes, and antioxidants, but also have very low content of calories, toxins, and sodium. Being antiviral and antibacterial in nature, green vegetables can successfully inactivate carcinogens, halt metastasis and pause the formation of a tumour. Certain vegetables contain isothiocyanates that can detox the cells. Some of the vegetables that are mighty effective in countering cancer cells include kale, romaine, watercress, nutritious, spinach, collard greens etc.
Berries: Berries are one of the best antioxidants among all food items, owing to their high ORAC score. Their antiviral and anti-fungal nature of berries is extremely healthy for the body. Moreover, abundant supply of vitamin A and C makes berries a perfect agent for increasing body immunity. Free radicals are one of the top reasons for metastasis. The proanthocyanidin content of berries helps the body to get a hang of free radicals, thereby decreasing the chances of cancer cells to grow rapidly. They can be consumed daily with any meals.
Spices and herbs: There are a lot of herbs and spices, which boost the immune system and prevents cancer cells to grow further. Turmeric, for instance, is scientifically proved to be a great agent for reducing tumor size and effectively countering breast cancer and colon cancer. Some of the other herbs and spices include black pepper, ginger, raw garlic, parsley, oregano, and basil. They can be consumed daily in the form of juice or along with regular meals.
Organic meat: Many scientists are of the view that organic meat does wonder in a cancer diet. Liver of beef and chicken has high B12 content and helps to remove harmful toxins from the digestive tract and liver. They can balance hormone, digest fat and counter the side effects of triglycerides, drugs, and obesity. This can be included in the diet every alternate day.
Seeds and nuts: Flax seeds and chia seeds are few nutrient-power packed foods in the world. They should be included in the diet due to high fiber, mineral, and fatty acid content. Some other healthy seeds that can pay rich dividends in fighting cancer include walnut, sprouted bean, sunflower seeds etc. Nuts and seeds with all their nutritional qualities can successfully stop metastasis, reduce tumor size and increase immunity in the body, if consumed daily.

World Cancer Day - 5 Amazing Foods That Help Fight Cancer!

Breast pain, also known as mastalgia, can be termed as any type of discomfort, pain or tenderness in and around the breast or the underarm region. It can also be accompanied by a sharp pain or a burning sensation. 
There are two major types of breast pain
Cyclical Pain: As the name suggests, this type of pain occurs on a cyclic basis and is linked with one s menstrual cycle. It may happen when one is going through her periods and is influenced by hormonal imbalance. This type of pain is generally not a cause of concern.
Non-Cyclical Pain: This is generally not common and its cause can be linked to a variety of reasons; cancer or a malignant tumour in the breast being the most severe consequence.


Causes of Breast Pain
Lumpy breasts along with soreness and pain can be caused due to fibrocystic breast tissue.
Hormonal imbalance can also lead to pain or discomfort in and around the breast region. Abnormal prolactin limits can also be a contributing factor.
Breast cancer can also lead to pain, mostly in the left breast. Along with the pain, it can also induce a dull ache, tightness or heaviness in the chest.


Treatments for Breast pain
The various treatments for cyclical breast pain include:
Making modifications in the diet
Administering Vitamin E and calcium supplements
Including thyroid hormonal supplements in the diet
Reducing sodium intake in your diet
For non-cyclical breast pain, which is often the cause of cancer, a thorough examination is recommended. A clinical biopsy will be advised if the lumpy tissues make the tumour harder to be detected through a mammogram.
If the pain is on account of an injury, then appropriate painkillers will have to be administered to reduce the pain.


Breast Pain - Understanding the Types and Reasons Behind it

Benign prostatic hyperplasia or BPH is a condition where the prostate gland gets enlarged. This is mostly common in men who are ageing. When the prostate gland gets enlarged, the flow of urine through the urethra gets blocked, and hence, several problems related to urination may occur. BPH occurs as a result of hormonal imbalance. If untreated, BPH can lead to severe bladder and urinary health conditions.
There are several symptoms and signs of benign prostatic hyperplasia. Here are 7 common symptoms:

1. A frequent need for urination: Men affected by BPH feel an increased need to urinate frequently. This gets enhanced during the night and is called nocturia. The patient may even need to urinate more than eight times a day. Due to the enlarged prostate gland, more pressure is put on the urethra, which leads to uncontrollable urination.
2. Urinating difficulties: The act of urination becomes difficult. Because of enhanced pressure on the urethra, the flow of urine to the penis from the bladder gets blocked. This makes a urine stream hard to start. The urine stream gets weak and interrupted, and more difficulty may be experienced during the end of urination.
3. Pain during urination and ejaculation: Due to pressure on the urinary tract and reproductive system, pain can accompany urination and ejaculation. Some patients tend to push urine out, which results in pain. The pain may also occur because of infection during BPH.
4. Blood in urine and an unusual color/smell: Urine may take a dark color and have an unusual smell due to urinary retention. Unpleasant urine smell signifies urinary tract infection. Blood in the urine may also result because of dilated veins present on the surface of the enlarged prostate.
5. Urinary retention: When a patient is unable to pass any urine, it is called urinary retention. Such a condition requires immediate treatment, and you need to consult a doctor immediately.
6. Urinary tract infections: Bacteria may start growing in the bladder when the bladder is not fully emptied of urine. This bacterial infection causes darkening of the urine, and emission of a foul odor.
7. Bladder stones: Bladder stones may develop because of the inability of the bladder to empty itself completely. This is a major symptom of BPH. Hard lumps of minerals or bladder stones are formed when the urine present in the bladder gets highly concentrated, which causes the crystallization of minerals. Bladder stones may cause infections, result in blood in urine, cause bladder irritation and may also block urine flow.

So you see that benign prostatic hyperplasia involves the enlargement of the prostate gland, and results in several problems related to urination and different symptoms. Hence, immediate treatment is advisable.

7 Symptoms of Benign Prostatic Hyperplasia

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