Tuberculosis is one of the most serious infectious diseases and can easily spread from one person to another when the virus enters the air through a sneeze or a cough. The disease is partly preventable by vaccines. It was once upon a time quite rare, but today has become quite common in urban areas. The emergence of HIV is one of the main reasons for this. HIV is an immune system disorder that weakens the body s ability to fight back against infections. With time, the virus causing the disease has evolved and become resistant to many drugs used to treat it.

Tuberculosis is also more commonly seen in slum areas of the cities. This is because of a lack of ventilation and living in close proximity that makes it easy for the disease to spread from one person to another. Limited access to safe drinking water and proper sanitation also reduces immunity and increases the risk of tuberculosis.

To control the spread of tuberculosis, it is important to treat it and keep away from other people while being treated. People also need to be made aware of the disease and its symptoms. It is important for the general public to understand that tuberculosis can be treated. They should also be informed that treatment of tuberculosis is free. As with most chronic diseases, the earlier treatment is started, the easier it is. 

Thus, if you notice any of the early symptoms of tuberculosis such as 

Weakness
Low fever 
Unexplained Weight loss
Then, you must consult a doctor immediately.

Tuberculosis can be diagnosed through a simple skin test or blood test. In terms of the skin test, the results can take up to 72 hours. It is important to note that this test is not foolproof as it can give a false positive or false negative result. For this reason, this may be followed by a blood test. Treatment for tuberculosis takes the form of oral antibiotics. The disease is no longer contagious after the medication is taken for a few weeks. 

However, taking the full course of medication is essential to stopping medication early can make the bacteria resistant to the drug. Tuberculosis caused by drug-resistant bacteria is much harder to treat.
Thus, to reduce the number of cases of tuberculosis in urban areas, people must be made aware of the disease and its treatment. Proper sanitation and ventilation in their living areas should also be provided. 

Tuberculosis - How It Is Affecting The Urban Population?

Tuberculosis is an opportunistic infection caused by the bacteria Mycobacterium tuberculosis. The infections occurring in people with weak immunity as compared to the people with a healthy immune system are called as opportunistic infections. As, HIV enters the human body, it replicates and weakens the immune system which in turn increases the risk of contracting Tuberculosis in people already suffering from HIV infection.

An HIV and Tuberculosis co-infection occurs when an individual has both, the HIV infection and an either latent or active TB disease simultaneously.  Each disease acts in speeding up the progress of the other, when HIV and TB infection is present together in the body. HIV infection speeds up the progression from latent to active Tuberculosis, Mycobacterium tuberculosis also accelerates the progression of replication and spread of the HIV infection.

HIV infection and Tuberculosis are totally different type of infectious diseases. HIV is a viral infection and TB is a bacterial one. An HIV infected person will not contract TB unless a contact happens with a TB infected person. TB spreads via droplet infection and is communicable. If a person lives in a country with a high prevalence rate of TB, an HIV patient is highly susceptible to contracting the infection. In the similar manner, a person suffering from TB gets infected with the HIV infection only through the blood and bodily fluids borne route, with unprotected sexual intercourse with an HIV infected individual being the most important cause.

Amongst all the other opportunistic infections, TB occurs at an earlier stage in the course of an HIV infection than most other opportunistic infections. Mortality rate in the co-infected patients is more than twice that of HIV infected individuals without a TB infection. Even if a patient is undergoing anti-retroviral therapy, the death rates remain high in co-infected individuals.The natural history and course of TB gets altered in people with an infected immune system. The damage to immunity due to HIV infection causes a drastic reduction in the pathogen killing capacity of the body. In such patients if there is no anti-retroviral treatment prescribed, then the latency period between the infection and progression of disease gets eliminated. 

An active phase of TB is observed in such individuals progressing within a short span of time, ranging from weeks to months, rather than years as it normally should be spanning. Risk of progression from a latent stage to an active stage of TB is around 10-15 times greater in an HIV infected individual as compared to the non-infected person. Such individuals also communicate the disease more rapidly to others.Pulmonary tuberculosis in an HIV infected person can present similar symptoms like that of a classic TB disease. However, a co-infection can sometimes show less presenting TB symptoms, where even the chest X-ray scans can be observed to be normal. A  subclinical  phase of Tb in co-infected patients can cause delay in the diagnosis of the symptoms and subsequently affect the prognosis due to lack of timely treatment.

Social stigma and discrimination has caused an obstacle in provision of adequate treatment for people with HIV. Proper counseling  and initiatives taken to provide indiscriminate care can aid in identification of co-infection and earlier stages. Anti-retroviral treatment teamed up with anti-tubercular drug regimen is prescribed and a successful treatment for drug sensitive cases of TB can be provided with medications for 6-8 months.

How HIV & TB  Are Related?

Pulmonary diseases are some of the most commonly experienced health conditions all over the world. Millions of people suffer due to various causes including genetics, smoking, pollutants and infection. Now lungs are one of the most important and complex organs of the body. They are the apparatus through which oxygen enters and carbon dioxide gets expelled. 

Lungs expand and contract on a constant basis to ensure that we can breathe properly. Let us find out more about lung or pulmonary diseases.

Asthma: This is one of the most common and potentially fatal conditions that affect children and adults. It grips the airways formed by the bronchi which branch off into smaller tubes from the main trachea that holds them. This condition causes inflammation, and even spasms, which can lead to wheezing and breathlessness. The main triggers of asthma attacks include allergies, infections and pollutants that may escape into the airways.
COPD: This is also known as Chronic Obstructive Pulmonary Disorder. It is an umbrella term used for various lung conditions that cause breathing difficulties due to an obstruction of the airways. Chronic bronchitis is one of the conditions that falls under COPD, and is usually characterised by persistent, hacking coughs.
Cystic Fibrosis: This is another condition that affects the airways by causing poor passage of mucus from the bronchial tubes. This condition is a genetic one where the mucus that gathers eventually becomes a lung infection.
Pneumonia: This is a condition that causes an infection in the alveoli, which are the tiny tubes that the airways branch into. These are air sacs that can catch myriad infections like pneumonia.
Tuberculosis: This is also a kind of pneumonia, which is caused by bacteria called Mycobacterium Tuberculosis. This condition usually attacks the air sacs of the lungs and can be a potentially fatal disease if it is not treated on time. The patient will require immediate hospitalisation.
Pulmonary Edema: This condition is caused by fluid leaks from the tiny blood vessels into the surrounding air sacs within the lungs. It can also be caused due to heart failure as well as back pressure which falls on the lungs. Direct injury to the lungs can also lead to this condition.
Lung Cancer: This is a fatal disease which can be found in any part of the lungs. It has many forms and the type as well as the location usually determines the kind of treatment option that will be followed.
Acute Respiratory Distress Syndrome: When the lungs suffer a sudden injury which is usually caused by a bout of serious illness, it is called ARDS. Treatment involves the use of life support ventilation.

All About Pulmonary Diseases

Tonsillitis, in the easiest terms, is the swelling of tonsils in our throat that is accompanied by symptoms like throat pain, difficulty in swallowing/ drinking, altered voice and fever etc.

As in the case of most infections, the occurrence of tonsillitis is more common in children due to relatively lower immunity and habits that invite infections. Let's take a look at the first line of defence when you have a cranky child with swollen tonsils.

1. Make your child gargle with salty warm water: This treatment is most helpful in any infection in the mouth. Add half teaspoonful of salt to a glass of warm water and make the child gargle with the mixture as many times in the day as possible (to a maximum of 5 times). Continue till the condition prevails.

Make sure the child spits out the water and not drinks it.

2. Antibiotics: Consult the ent specialist and have the antibiotics if it is a bacterial cause as per the doctor. Take the alternative treatment prescribed in case of other causes. The entire course of medication should be completed even if the kid gets better sooner to eliminate all traces of bacteria.

3. Painkiller/numbing lozenges: Painkillers that are prescribed by the doctor can be given to ease the pain. Same is the case with lozenges but care should be taken that he/she should not have too many of these.

4. Allow him/her to take rest: It does help in a betterment of the condition!

5. Give warm (not hot) soothing food: Soup, ginger honey mixture, ginger tea can help soothe the inflamed tonsils in most cases. The condition, more often than not, gets better within 7-10 days.


Best Ways to Deal With Tonsillitis in Kids

Cystic Fibrosis is a genetic disorder that is known to affect some of the vital organs of the body including the lungs, digestive system to name a few. For long it was believed that cystic fibrosis affects a person in their childhood. However, various research and studies suggest that adults are also susceptible to this inheritable disorder. In this article, we will discuss the cause and symptoms associated with cystic fibrosis.

Cause
The epithelial cells that line the stomach, nasal cavity and lungs, are responsible for the production of the digestive fluids, sweat, tears, mucus. The Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) gene codes for a protein called the CFTR protein. The CFTR protein, a membrane protein plays a pivotal role in transporting the chloride ions of the epithelial cells inside and out of the cell. This regulation of the chloride ions goes a long way in ensuring that the mucus produced is free-flowing and thin.

In the case of Cystic Fibrosis, the CFTR gene that codes for the protein undergoes a mutation. With the CFTR protein unable to perform its function, sticky and thick mucus builds up and clogs some of the major systems of the body including the digestive system, reproductive, and respiratory system. There is also a higher salt content in the sweat of the affected person.

For a person to be affected by cystic fibrosis, he/she must inherit a copy of the mutated CFTR gene from both the parents ( Autosomal Recessive Disorder) at birth.

Symptoms
The symptoms associated with cystic fibrosis depends on the organs and systems affected.

The thick mucus formed can clog the digestive tract resulting in incomplete absorption of the essential nutrients from the food. This may have an impact on the overall growth and development of the body.
- There may be stunted growth or no weight gain.
- The stool may appear greasy and foul smelling. Some may also suffer from constipation.
- Newborns and infants may suffer from an intestinal blockage.
Cystic fibrosis, left unattended can lead to diabetes, intestinal blockage or obstruction.
- The mucus can also block the bile duct triggering a host of problems including liver disorders.
- At times, the obstruction or blockage can occur at the junction where the large and the small intestine meets (Distal intestinal obstruction syndrome).
The thick mucus can also affect the lungs and the respiratory system by blocking the tubes that act as a passage carrying the air inside and out of the lungs. As a result,
- A person may suffer from lung infections frequently.
- There may be difficulty in breathing, stuffy and blocked nose, or wheezing.
- Some people may also suffer from a chronic cough with a thick sputum.
Left untreated the complications can worsen resulting in

Nasal polyps, Chronic infections, Hemoptysis (there is blood while coughing), and Pneumothorax (air fills up in the space bifurcates the chest wall from the lungs).

In severe cases, there may be a respiratory failure.

Cystic fibrosis can also trigger fertility problems (both in males and females).

Cystic Fibrosis- Causes and Symptoms!

If you are having a chronic cough and often pant for breath, it is quite possible that you may be suffering from bronchitis. In addition to this, you may also experience wheezing, fatigue, and pain in the chest. It is triggered when the lining of the airways in the lungs become irritated. To determine, whether or not bronchitis is contagious, it is important to understand what caused the ailment.

Chronic bronchitis: This type of bronchitis happens when the airways get continuously irritated. It may last for months or even years and tend to come back. It is caused by irritants that affect the lungs such as dust, chemicals, smoke, fire, and smoking cigarettes. Even though chronic bronchitis is not considered contagious, it is a serious health issue that requires medical attention.
Acute bronchitis: It generally lasts for about 1 to 3 weeks and stems from cold or flu virus. As these infections are contagious, so is acute bronchitis.
Whether a person having bronchitis can spread the disease depends on the virus that is causing the ailment. In most instances, it is seen that the disease is contagious for a first few weeks of infection. Since there are hundreds of viruses causing bronchitis, it is best to assume that a person is bound to spread the disease when he has symptoms of cold and flu.

What causes transmission of bronchitis?
Acute bronchitis owing to infection is generally transmitted via an airborne droplet containing germs. It is transmitted when someone having infection shakes hand or sneezes or coughs or has any other physical contact. Some virus and bacteria have the power to live outside the body for a prolonged span of time, and therefore, you can get infected by touching any object that is harboring the germs.

It is often seen that acute bronchitis begins as flu and therefore, the best way to prevent it is to get an annual shot of flu. When you come in contact with an infected person, the chances of being affected is high if you have chronic infections or weak immune system. Aged people and young children are most vulnerable to this disease.

How can acute bronchitis be prevented?
Even though acute bronchitis is extremely common and can occur at any time, winter is the most vulnerable season for bronchitis. But there are ways in which you can prevent bronchitis effortlessly. You should avoid close contact and sharing of utensils with an infected person who has flu, cold or bronchitis. You should not touch a used tissue since the virus of bronchitis can easily spread through mucus. Make sure that you get the annual flu shot and wash your hands in warm water.

The disease is very common, and it can make you feel very uncomfortable at times. But there are times when the symptoms subside on their own without any sort of medical attention.

Is Bronchitis Contagious?

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