Causes and symptoms of acute tubular necrosis

Damage or destruction to tube-like structures known as tubules in the kidneys can bring about the development of acute tubular necrosis (ATN) and subsequently, acute kidney failure.

What causes acute tubular necrosis (ATN)?

A lack of supply of oxygen to the cells in the kidney is the most common cause of this condition. The reason as to why oxygen may not reach the cells and tissues of this organ could be restriction or blockage of the pathways. When this happens, the kidneys get damaged. Dehydration is the most important cause of ATN which may be because of loose motions, vomitings, heat stroke etc.

Health conditions such as diabetes, heart attack, and stroke can bring about a decrease in blood flow to the organs resulting in ATN and death of cells. Similarly, the presence of toxic substances in the blood can also lead to tubules damage and change the way the cells function in the tubules.

Other causes that may lead you to develop ATN may be medications, radiology dyes, anesthetics and chemicals that cause your body to react adversely.

In addition to these causes, a number of factors can put you at risk of ATN and there are:

- An injury to the body, more specifically your kidneys can cause clotting of the blood vessels
- An adverse response to blood transfusion
- Instances of septic shock can slow down blood flow to the organs
- A major surgery that can interrupt blood supply to the organs

What are the symptoms of the condition?

The symptoms associated with the condition can vary depending on the severity of the problem.

You may experience:

- Troubles in waking up
- Drowsy feeling even during daytime
- Feelings of lethargy
- Feelings of excessive thirstiness
- Problems with urination
- Fluid retention problems
- Instances of confusion
- Feelings of nausea



Can Acute Tubular Necrosis Cause Kidney Failure?

The main task of the kidneys is to balance the electrolytes in the blood and maintain the pH homeostasis. The kidneys also remove waste products from the blood. Infections in the kidney aren t uncommon and affect women (majorly pregnant women) and children below the age of two in most conditions.

Kidney infections are of two types:

Uncomplicated kidney infection: The infections in this condition are minor and can be cured with minimal medication.
Complicated kidney infection: These infections are more complex and serious as compared to the uncomplicated ones.
If not treated on time, kidney infection can prove to become a serious condition and lead to various complications including kidney damage and blood poisoning (sepsis).

The most common causes of kidney infections are:

Weak immune system: If you have a weak immune system, you are prone to getting a bacterial or fungal infection on the surface of your skin which eventually enters the bloodstream. The infection might right reach the kidneys and cause an infection there.
Bacteria entering from the urethra: The pathogen which causes an infection can enter the body through the urethra and multiply in the bladder. The infection spreads to the kidneys and causes renal infection.
Kidney stones: People diagnosed with kidney stones are at a very high risk of developing kidney infections. Kidney stones are caused because of a build-up of dissolved minerals in the inner lining of the kidneys.
Enlarged prostate: Men with an excessively enlarged prostate are prone to developing kidney infections as compared to men with a normal-sized prostate.
Intercourse: Engaging in sexual (anal or vaginal) intercourse with an infected person can be a major reason for kidney infection as the bacteria can enter the body through the anus or the vagina and affect the kidneys.
It is not difficult to detect infection in the kidneys as they have very visible symptoms. A few symptoms of kidney infection are:

Excessive back pain
Sudden chills or fever
Nausea and puking
Blood in the urine
Pain while urinating

Kidney Infections - Factors That Put You At Risk!

The urethra is a thin tube that is responsible for carrying urine from the bladder. The urethra is wide enough to facilitate a free flow of urine. However, in some cases, the tube can narrow down and it can restrict urinary flow. This condition is known as a urethral stricture. It is a condition that affects mostly men.

Causes:
The inflammation of the tubular tissues or the presence of scar tissue is the number one cause for urethral stricture. In some cases, an accident or the injury to the groin area can also lead to the formation of such thin tubes. The other factors can include pelvic fractures, radiation, urinary infection and in some cases even STDs(Sexually Transmitted Disease).

Symptoms:
Most of the symptoms of Urethral stricture are mild. Only in some rare cases, the symptoms can be extreme. These can include weak or restricted urine flow, frequent urges to urinate, and feeling of heaviness in the bladder, a burning sensation during urination, swelling and pain while urinating. Sometimes your urine may discharge volts of blood and the color of urine may change.

Diagnosis:
Diagnosis is by a physical examination and by analyzing the urine samples. In most of the cases, the thickness of the walls is measured by cystoscopy. The rate of the urine passed may also be checked for identifying the symptoms.

Treatment:
Treatment depends on the severity of the condition. Nonsurgical methods aim to improve the width of the urethra. This is done by using an instrument called a dilator. This is done as an outpatient procedure. This procedure is the most common method done and is done for most of the milder cases. Surgery is another option. The surgery aims to remove the heaviness of the urethra and enlarges the size of the flow.

Urine Flow Diversion:
This is done in extremely rare cases if the bladder has to be completely removed. In those cases, hole in the abdomen is done and urine is bypassed to that hole. However, this is an extremely rare scenario.

Prevention:
Try to avoid injuries in the groin area. If you are playing sports or a fitness enthusiast, use proper protection for your abdominal and groin regions. Try to always have safe sex and if you feel that there is some discomfort or some uneasiness while passing urine, do consult with a doctor immediately. In many cases, the condition can be avoided if proper precautions are taken.

What Is Urethral Stricture?

What are the functions of the kidney? 

The kidneys filter waste and excess fluid from the blood. As kidneys fail, the waste accumulates in the body. The two most important enzymes, which kidney makes are erythropoietin & renin. Erythropoietin are made by the kidneys if there is less oxygen in the blood. It tells the bone marrow to make more red blood cells. So this means there will be more oxygen carried in the blood.

Renin is made by the kidney if there is low blood pressure, low volume of blood, or too low salts in the blood Renin make the blood vessels smaller and tells the adrenal gland to make aldosterone. It also makes a person feel thirsty and all of this makes the blood pressure go up. Since Kidney plays a very important role in the overall functioning of the body, it s very important to take care of its health. 

Let s have a look on various kind of kidney disease including the one which are chronic:

Kidney stones
Kidney Infections
Glomerulonephritis
Congenital Kidney disease
Diabetic Nephropathy
Hypertensive Nephropathy
Cancer 

Now what is Chronic Kidney Disease?
Chronic kidney disease include conditions that damage your kidneys and decrease their ability to keep healthy by doing the jobs listed, if it gets worse, wastes can build to high levels in the blood and make person sick.
Chronic kidney disease is caused by diabetes, high blood pressure and other disorders.

What causes chronic kidney disease?
The two main causes of chronic kidney disease are diabetes & high blood pressure which are responsible for up to two third of the cases. Other conditions that affect the kidney are:
1. A group of diseases that cause inflammation and damage to the kidney s filtering unit.
2. Inherited disease such as poly cystic kidney disease.
3. Malformation that occur as a baby develop in mother s womb.
4. Lupus and other disease that affect the body s immune system.
5. Repeated urinary infections.

What are the symptoms of chronic kidney disease?
1. Feel more tired and have less energy
2. Have trouble concentrating
3. Poor appetite
4. Trouble sleeping
5. Muscle cramping at night
6. Swollen feet and ankles
7. Puffiness around the eyes especially in the morning
8. Dry itchy skin
9. Need to urinate more often, especially at night. 
In case of the similar symptoms one needs to get it diagnosed and connect with the physician for good care and treatment. Stay Healthy!

Chronic Kidney Disease - 9 Symptoms that Can Help You Detect it 

The kidneys filter the blood and eliminate the waste products through urine. The waste deposition is sometimes in the form of excessive calcium, uric acid and other undesirable contents. It causes the urine to get highly saturated. The solid depositions then turn into stone like formations, also termed as renal lithiasis or calculi. There are different kinds of kidney stones, which are differentiated based on its varied constituents. Kidney stones cause excruciating pain and uneasiness. Frequent urination and discomfort during urination, presence of blood in the urine, are some major signs of kidney stones.

Kidney stones can be prevented by maintaining a healthy lifestyle and a balanced diet with sufficient nutrients:

Calcium and oxalate-rich food should be consumed together. This leads to the binding of calcium and oxalate together in the stomach intestines, before they can be processed in the kidneys. This helps to control the formation of calcium and oxalate depositions in the kidneys.
Do not cut down on calcium. Since most of the kidney stones are found to be calcium depositions, many people tend to cut down on their calcium intake. It is important to continue with food that is rich in calcium such as milk. However, it is necessary to reduce intake of other calcium supplements. Decrease in calcium can lead to degeneration and deformation in bones and muscles.
Too much of red meat consumption and high fat dairy products can lead to the formation of stones in the kidneys. Animal protein is rich in purine that increases uric acid, saturating the urine and creating stones. It is important to balance your diet by including lots of green vegetables, whole grains, fibres, fruits and low-fat dairy products. Opt for non-animal protein such as lentils or legumes.
Cut down on sugary and aerated drinks. They contribute to the formation of depositions due to their high and unhealthy levels of fructose and preservatives.
Reduce or abstain from alcohol. Alcohol is known for its multiple disadvantages to the human body. It has also been found to increase the levels of uric acid in blood.
Keep your body hydrated. Drink adequate quantity of water throughout the day, preferably 3 litres or more depending on your physical activities. It prevents the solidification of the depositions and helps to eliminate wastes smoothly.
Increase the intake of anti-oxidants in the form of green tea, dark chocolates and fruits.
Lower the intake of salt. If you wish to discuss about any specific problem, you can consult a urologist.

Kidney Stones - 8 Diet Tips to Prevent It!

Kidney failure or infections are usually unsafe and serious diseases. Their consequences affect every single other organ in the body. Minor problems in the kidney may demonstrate no side effects. However, when the sickness progresses, it can bring about numerous serious indications, for example, seizure, tissue squandering, gastrointestinal bleeding and a failure state. Total kidney failure requires routine dialysis until a transplant operation can be performed.

Homeopathy, on the other hand, is a very effective cure for kidney problems. It eradicates the problem from its roots and helps prevent any further diseases and problems in the kidney. Homoeopathic solutions have had been successful in treating kidney diseases for which standard prescription give no cure and are not effective. Some of the homoeopathic cures are as follows:

Ammonium carb's rubrics: Taken when there is excruciating pee. This includes white, burning, insufficient, painful or orange urine with drowsiness and weakness.
Apis mel's rubrics: These are used when there is general oedema or swelling, kidney aggravation and inability to pass urine.
Arsenic alb's rubrics: This occurs when there is trouble in passing urine. Also useful in case of uremia, nephritis, urgent need to urinate or urinating without knowing.
Aurum met's rubrics: When there is difficulty in maintenance of urine and the urine constitutes of mucous like residue.
Berberis' rubrics: When there is hypertension, renal (kidney) stones, dull yellow or green urine and neuralgic pain originating from the kidneys.
Cannabis indica s rubric: Used in case of a urinary tract diseases.
Cantharsis' rubrics: This is used in cases of delicacy in kidney regions, renal colic and nephritis (kidney irritation).
Chelidonium's rubrics: These are effective when a person goes through the urge of urinating a lot at night when there are abundant urination and pale white pee.
Cuprum Aas' rubrics: When there is kidney failure, excruciating pee and stained pee.
Cuprum met's rubrics: It is used when a person goes through bed-wetting, extremely watery urine, and feels shooting pain in the urethra.
Helonia's rubrics: Used when there is kidney irritation, albuminous (white) pee, sickliness, cramps and bluntness.
Juniper's rubrics: Used when there is difficulty in retaining water.
Kali carb's rubric: Used in case of kidney stones, and is a general solution for problems in the kidneys.
Sanicula's rubrics: Used when the bladder is swollen, there are kidney stones and kidney irritation.
Terebinthum's rubrics: When there is blood in the urine, kidney irritation and urinary tract aggravation.
Urea's rubrics: In cases of are general oedema (swelling because of water maintenance) and extreme pain in the urethra.
Opium's rubrics: Used in cases of uremia (a type of blood disease), general oedema, dark stool, white urine, concealment of urine, swelling of the stomach, mucous-like urine and uremic shakings.

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