Glomerulonephritis is a disease that is caused due to inflammation of the small filters that are present within the kidneys or glomeruli. Glomeruli eliminate the excess waste, electrolytes and fluids from the blood, discharged through urine. A glomerular disease can be either acute or chronic. If the condition arises without a combination of any other disease, it is termed as primary glomerulonephritis. Secondary glomerulonephritis is characterized by diabetes or lupus (an auto-immune disorder) being at the root of the disease. Prolonged or severe inflammation can take a toll on the kidneys.


Causes-


Nephrotic syndrome can be primary, being a disease specific to the kidneys, or it can be secondary, being a renal manifestation of a systemic general illness. In all cases, injury to glomeruli is an essential feature. Kidney diseases that affect tubules and interstitium, such as interstitial nephritis, will not cause nephrotic syndrome.


Primary causes of nephrotic syndrome include the following, in approximate order of frequency:
Minimal -change nephropathy
Focal glomerulosclerosis
Membranous nephropathy
Hereditary nephropathies


Secondary causes include the following, again in order of approximate frequency:
Diabetes mellitus
Lupus erythematosus
Viral infections (e.g., hepatitis B, hepatitis C, human immunodeficiency virus [HIV] )
Amyloidosis and paraproteinemias
Preeclampsia
Allo-antibodies from enzyme replacement therapy


Nephrotic- range proteinuria may occur in other kidney diseases, such as IgA nephropathy. In that common glomerular disease, one third of patients may have nephrotic- range proteinuria.


Nephrotic syndrome may occur in persons with sickle cell disease and evolve to renal failure. From a therapeutic perspective, nephrotic syndrome may be classified as steroid sensitive, steroid resistant, steroid dependent, or frequently relapsing.


Treatment-
Whether one is suffering from acute or chronic nephrotic glomerular , with symptoms moderate or severe, the treatment lies in treating high blood pressure and other underlying conditions of the disease.
Water pills help control sweating, thus increasing the fluid flushed from the kidneys.
Statins reduce cholesterol level.
Blood thinners such as anticoagulants lower the risk of blood clots.
Corticosteroids regulate the immune system and ease the inflammation that results from kidney disorders.
Incorporating certain lifestyle changes such as opting for lean proteins, cutting on the intake of fat in the diet and consuming lesser amounts of salt can treat inflammation and swelling.
For kidney failure, dialysis can come to the aid in eliminating excess fluids and regulating hypertension.


Nephrotic Syndrome: Causes and Treatment

What are the functions of the kidney? 

The kidneys filter waste and excess fluid from the blood. As kidneys fail, the waste accumulates in the body. The two most important enzymes, which kidney makes are erythropoietin & renin. Erythropoietin are made by the kidneys if there is less oxygen in the blood. It tells the bone marrow to make more red blood cells. So this means there will be more oxygen carried in the blood.

Renin is made by the kidney if there is low blood pressure, low volume of blood, or too low salts in the blood Renin make the blood vessels smaller and tells the adrenal gland to make aldosterone. It also makes a person feel thirsty and all of this makes the blood pressure go up. Since Kidney plays a very important role in the overall functioning of the body, it s very important to take care of its health. 

Let s have a look on various kind of kidney disease including the one which are chronic:

Kidney stones
Kidney Infections
Glomerulonephritis
Congenital Kidney disease
Diabetic Nephropathy
Hypertensive Nephropathy
Cancer 

Now what is Chronic Kidney Disease?
Chronic kidney disease include conditions that damage your kidneys and decrease their ability to keep healthy by doing the jobs listed, if it gets worse, wastes can build to high levels in the blood and make person sick.
Chronic kidney disease is caused by diabetes, high blood pressure and other disorders.

What causes chronic kidney disease?
The two main causes of chronic kidney disease are diabetes & high blood pressure which are responsible for up to two third of the cases. Other conditions that affect the kidney are:
1. A group of diseases that cause inflammation and damage to the kidney s filtering unit.
2. Inherited disease such as poly cystic kidney disease.
3. Malformation that occur as a baby develop in mother s womb.
4. Lupus and other disease that affect the body s immune system.
5. Repeated urinary infections.

What are the symptoms of chronic kidney disease?
1. Feel more tired and have less energy
2. Have trouble concentrating
3. Poor appetite
4. Trouble sleeping
5. Muscle cramping at night
6. Swollen feet and ankles
7. Puffiness around the eyes especially in the morning
8. Dry itchy skin
9. Need to urinate more often, especially at night. 
In case of the similar symptoms one needs to get it diagnosed and connect with the physician for good care and treatment. Stay Healthy!

Chronic Kidney Disease - 9 Symptoms that Can Help You Detect it 

Kidney failure and other kidney problems are the leading causes of death nowadays. Common problems that lead to kidney failure include chronic blood pressure and chronic uncontrolled diabetes. However, there are a number of ayurvedic medications which help solve kidney failure and other kidney problems including;

1. Punarnava

Punarnava is commonly called hogweed as well but the medical name for it is boerhavia diffusa. It is extremely helpful in preventing micturition, a disorder which is characterized by unexplained fainting after urinating. However, that is not the only symptoms hogweed helps with as it also removes excess water from the body due to kidney failure.

2. Varun

Varun is commonly known as caper and is medically known as crataeva nurvala. The diseases which varun is best at dealing with are urinary tract infections and renal stones. Varun also helps in stopping the swelling and extra fluid accumulation after kidney failure.

3. Gokshura

Gokshura is known as tribulus terrestris and is an herbal tonic for the genito-urinary system. Gokshura is one of the best ways to avoid dialysis. This is because it stops infections from occurring and also clears obstructions in the urinary tract. It is also very good at regenerating the kidney cells.

4. Raktachandan

Rakt chandan is known as p. Santalinus or red sandalwood and is another excellent remedy for kidney problems. It acts as both a diuretic and an anti-infectant.

5. Palaash

Palaash, medically, is known as butea monosperma. It is a type of urinary alkalizer and it also stops micturition. A urinary alkalizer is a medication which allows the urine to pass more easily. This is yet another great remedy for kidney failure.

6. Kaasni

Kaasni is commonly known as chicory but its medical name is cichorium intybus. Kaasni gives strength to the kidneys and is also a very good alkalizer. However, its most valuable property is the fact that it helps in nephritis and nephrotic syndrome (disorder of the kidneys characterized by protein loss).

Ayurveda and Kidney Problems

Infection caused in the kidneys, bladder, urethra or the ureters is known as urinary tract infection. According to doctors, women are generally more at risk of suffering from this condition than men. Some of the causes which contribute to the development of this infection are:

1. Invasion of bacteria: like any other infection, one of the causes of urinary tract infection is the invasion of the bacteria escherichia coli in the bladder. This type of bacteria is most commonly found in the gastrointestinal tract and is most often held responsible for urinary tract infection.

2. Spreading of the bacteria from anus to urethra: the spread of the gastrointestinal bacteria from the anus to the urethra leads to the infection of the urethra thereby causing urinary tract infection. 

Some of the symptoms of urinary tract infection are

1. A nagging urge to urinate: one of the most predominant symptoms of urinary tract infection is a persistent, nagging urge to urinate. You would know your urinary tract is infected when you feel the urgency to urinate extremely frequently.

2. There is a burning sensation when you urinate: the symptoms of urinary infection are extremely visible and are felt intensely by the one suffering from it. If you feel a burning sensation while urinating, chances are extremely high that you are suffering from urinary tract infection.

3. Red colored urine: sometimes your urine may contain perceptible amount of blood in them. In most cases, presence of blood in urine is a definite sign of urinary tract infection.

4. Foul smelled urine: an internal infection in the urinary tract manifests itself in different ways. One of the chief symptoms of this infection is discharging foul smelling urine.

5. Pain in the pelvic area: women who suffer from urinary tract infection experience excruciating pain near the pelvic area, sometimes extending to the pubic bone.

Causes and Symptoms of Urinary Tract Infection

The kidneys are small organs that filter about 200 liters of water each day, removing out about 2 liters of toxins and wastes in a water medium as urine. In addition to maintaining the fluid levels in the body, they also produce hormones that regulate blood pressure, produce red blood cells, and play a vital role in maintaining bone health. Any problem with the kidney, infection or otherwise, can lead to its improper functioning, causing damaging results on the rest of the body organs.

While the bad news is that most diseases from infections to diabetes to hypertension and cancer have an adverse effect on the kidneys, there are signs that can be watched out for, which can indicate a problem with the kidneys and so further damage prevented. Read on to know some of the most common symptoms of kidney disease and how further progression can be prevented.

Change in urination process: Any change in the process of urination should be a warning for a test. It could be change in color or the appearance of the urine, painful urination, burning on urination, difficulty to start and stop a stream, or too frequent or infrequent urinations. These are usually the first symptoms of kidney disease and should be an alarm to get a kidney function test done. If you have hypertension or a strong family history of kidney disease, then getting a simple urine test to check optimal kidney function is definitely mandated. These could indicate conditions like infection, diabetes, kidney failure, or other conditions which can all be identified with further testing and then treated accordingly. The progress of the disease can be halted, which can help improve overall quality of life.
Fatigue, loss of energy: As noted above, impaired kidney function leads to other organs being affected and buildup of toxins in the body. There is also anemia which sets in due to decrease in red blood cells and therefore reduced overall energy levels, loss of sleep, and fatigue.
Swollen eyes, feet, and ankles: Reduced kidney function leads to fluid accumulation, sodium retention, loss of protein, which all lead to swollen eyes and ankles and feet. These are easy to identify and should ring a bell to get checked for kidney functions.
Muscle cramps: Improper electrolyte levels can affect muscle functioning, leading to painful cramps. Along with changes in the process of urination, this should be an indication of underlying kidney disease.
Keep a track of any above mentioned problems as they can help in saving not just the kidneys but all the vital organs.

Kidney Problems - 4 Signs to Watch For!

Nephropathy is also known as renal disease. It is any type of damage or disease relating to the kidneys. Though not everyone with diabetes has nephropathy, however, diabetic nephropathy can cause kidney failure.

How does diabetes affect the kidney?
Kidneys are responsible for taking waste out from your blood. They have a lot of tiny blood vessels to do this. High blood sugar may kill such blood vessels. Once these blood vessels are destroyed, the kidneys may not function as well or it may even lead to kidney failure.

What increases your risk of getting diabetic nephropathy?
There are several factors which increase your risk of getting diabetic nephropathy including: \
1. High blood pressure
2. High cholesterol
3. Smoking
4. Being native american, african american or of hispanic origin, for whom risk factors have proved to be magnified
5. If you have family history of diabetic nephropathy

Symptoms and diagnosis:
There are very few noticeable symptoms, which appear when you have diabetic nephropathy, except swelling in your arms and legs. The diagnosis is done by checking for a type of protein in your urine known as albumin, which is not supposed to be there. Getting the diagnosis done early is crucial.

Preventive measures
You can prevent kidney damage by doing the following:
1. Keeping your blood sugar levels under control - keep hba1c &lt; 6-7%
2. Keeping your blood pressure under control in the range of 130/80
3. Eating healthy food
4. Exercising regularly
5. Not eating too much protein
6. Not eating too much salt
7. Reducing smoke or excessive tobacco usage

Medicines for treatment
If you do get diabetic nephropathy, here are some medicines, which can help cure it
1. Ace inhibitors which are also called angiotensin-converting enzyme inhibitors
2. Angiotensin ii receptor blockers (arbs)

Possible complications
1. Blood pressure may rise
2. Triglyceride levels and cholesterol levels may rise.

All About Diabetic Nephropathy

Don't wait any longer, manage your Renal Nurse online with a Lybrate doctor today

Consult for Renal Nurse - Online and Easy!

FilterClear All

COMMON SPECIALITIES

COMMON ISSUES