Glomerulonephritis is a disease that is caused due to inflammation of the small filters that are present within the kidneys or glomeruli. Glomeruli eliminate the excess waste, electrolytes and fluids from the blood, discharged through urine. A glomerular disease can be either acute or chronic. If the condition arises without a combination of any other disease, it is termed as primary glomerulonephritis. Secondary glomerulonephritis is characterized by diabetes or lupus (an auto-immune disorder) being at the root of the disease. Prolonged or severe inflammation can take a toll on the kidneys.


Causes-


Nephrotic syndrome can be primary, being a disease specific to the kidneys, or it can be secondary, being a renal manifestation of a systemic general illness. In all cases, injury to glomeruli is an essential feature. Kidney diseases that affect tubules and interstitium, such as interstitial nephritis, will not cause nephrotic syndrome.


Primary causes of nephrotic syndrome include the following, in approximate order of frequency:
Minimal -change nephropathy
Focal glomerulosclerosis
Membranous nephropathy
Hereditary nephropathies


Secondary causes include the following, again in order of approximate frequency:
Diabetes mellitus
Lupus erythematosus
Viral infections (e.g., hepatitis B, hepatitis C, human immunodeficiency virus [HIV] )
Amyloidosis and paraproteinemias
Preeclampsia
Allo-antibodies from enzyme replacement therapy


Nephrotic- range proteinuria may occur in other kidney diseases, such as IgA nephropathy. In that common glomerular disease, one third of patients may have nephrotic- range proteinuria.


Nephrotic syndrome may occur in persons with sickle cell disease and evolve to renal failure. From a therapeutic perspective, nephrotic syndrome may be classified as steroid sensitive, steroid resistant, steroid dependent, or frequently relapsing.


Treatment-
Whether one is suffering from acute or chronic nephrotic glomerular , with symptoms moderate or severe, the treatment lies in treating high blood pressure and other underlying conditions of the disease.
Water pills help control sweating, thus increasing the fluid flushed from the kidneys.
Statins reduce cholesterol level.
Blood thinners such as anticoagulants lower the risk of blood clots.
Corticosteroids regulate the immune system and ease the inflammation that results from kidney disorders.
Incorporating certain lifestyle changes such as opting for lean proteins, cutting on the intake of fat in the diet and consuming lesser amounts of salt can treat inflammation and swelling.
For kidney failure, dialysis can come to the aid in eliminating excess fluids and regulating hypertension.


Nephrotic Syndrome: Causes and Treatment

You're said to suffer from the problem of acute kidney failure if your kidneys suddenly stop working and lose their ability to eliminate waste materials including excess fluids and salts from the blood. The condition usually develops quickly over a few days or even a few hours. When this happens, waste materials accumulate in your blood, disrupting the chemical balance of your bloodstream.

So, what causes this problem?

Acute kidney failure can occur because of any one of these reasons:

1. A drop or slowdown of blood flow to the kidneys - Adequate blood circulation to the kidneys is of great importance as without it the kidneys may end malfunctioning. If blood flow to the kidney is hampered, a part of or the entire kidney may die. You may suffer from acute kidney failure if blood flow to the kidneys gets impaired due to conditions like

Heavy blood loss
Sepsis (body's inflammatory reaction to an infection, which can bring about organ failure, tissue damage, and death)
Injury
Use of certain drugs
Dehydration
Burns
Heart disease
2. Urinary obstructions - A sudden blockage that hampers your kidney's ability to eliminate urine can also bring about acute kidney failure. When this happens, it leads to a build up of toxins in the body, causing an overload of the kidneys. Conditions that bring about this urinary obstruction include:

Cervical cancer
Colon cancer
Bladder cancer
Kidney stones
Enlarged prostate
Prostate cancer
3. Disease within the kidneys - Even instances of clotting within the blood vessels of the kidneys can lead to acute kidney failure. This is because if the movement of blood cells within the blood vessels gets hampered, kidneys are not able to filter out toxins from the body. The conditions and diseases that may cause clotting, and subsequently damage to the kidneys include:

Scleroderma (an autoimmune disease that affects connective tissues and skin)
Build-up of cholesterol deposits
Glomerulonephritis (an inflammatory condition of the kidney's ball-shaped structures called glomeruli)
Hemolytic uremic syndrome (a condition that occurs due to untimely death of red blood cells)
Lupus (a disorder of the body's immune system that brings about damage to the body's own organs and tissues)

3 Causes of Acute Kidney Failure!

Kidney stones can range from being the size of a grain to a pebble. These stones can be described as crystallized mineral deposits in the kidneys. Some kidney stones can be passed out of the body along with urine while others may require surgery. Symptoms of having a kidney stone vary from mild to severe. In the case of very small kidney stones, the patient may not experience any symptoms at all. The 5 most common kidney stone symptoms usually experienced are:

Pain: Pain in the lower abdomen and back is one of the most common symptoms of having a kidney stone. This may be felt just below the ribs, on the centre and sides of the abdomen, in the lower back and in the groin. The intensity of pain is not directly related to the size of the kidney stone. This pain can come and go and will vary in terms of intensity. In certain cases, the pain can be severe enough to warrant a trip to the hospital. This pain is usually a sign that the stone is moving.
Frequent Urination: People suffering from kidney stones may find themselves needing to go to the bathroom more often than normal. In some cases, patients may also wake up in the middle of the night with the urge to urinate. However, only a small amount of urine may be passed at a time. This is a sign that the kidney stone has moved into the lower urinary tract. Small stones may later be passed out of the body along with urine.
Bloody Urine: Urine should ideally be pale yellow. Patients suffering from kidney stones may notice that their urine is darker than normal and cloudy. There may also be blood in the urine. This is known as hematuria. The colour of blood in such cases can range from pink to brown. Cloudy urine is also considered a sign of a urinary infection. This is a sign that the urine also contains pus cells or pyuria.
Nausea: Vomiting and nausea are common symptoms of kidney stones. This is caused by the nerve connections shared by the kidneys and the gastrointestinal tract. The presence of kidney stones in the kidneys or urinary system can trigger an upset stomach. Some people also feel nauseous because of the pain caused by kidney stones.
Foul Smelling Urine: Under normal conditions, urine should not have a very strong smell. Urine that smells bad is a symptom of a urinary infection. Bacteria in the kidneys or urinary tract can be the cause of this smell. It may also be caused by the high concentration of urine. 

5 Symptoms Of Kidney Stones!

Bladder cancer is characterized by irregular growth of abnormal tissue (tumor) on the lining of the bladder. This type of cancer may spread to the surrounding tissues or other body parts as well.

What are the causes?

Bladder cancer can be caused by environment-related factors and smoking. In fact, smoking tobacco is one of the major causes of bladder cancer around the world. The chemicals present in tobacco can irritate the bladder lining which ultimately leads to bladder cancer. It may also be caused by continuous exposure to chemicals such as dyes or leather dust and radiation. These chemicals tend to cause unusual changes in the cells of the bladder lining and causes cancer in the bladder.

It can also be caused by modifications in the dna in the cells of the bladder which may impair the functioning of the cells in the body. This can cause mutations in the bladder resulting in cancer.

What are the symptoms?

1. Presence of blood in the urine, often painless

2. Feeling of pain while passing urine

3. Back pain

4. Excessive urination

5. Infections in the urinary tract

6. Lower leg swelling

7. Pain in the bones, especially in the pelvic area

8. Weight loss

Treatment options

Treatments for bladder cancer depend on the stage of the cancer. The various treatment choices are:

Surgery - In some cases, these cancers are surgically removed by a surgeon. A type of surgery used is transurethral resection of bladder tumor (turbt) where the cancer cells are destroyed with laser by passing a thin fiber into the bladder.

Chemotherapy - In this method, medications are used to target and destroy cancer cells.

Radiation therapy - Radiation therapy uses rays such as x-ray or uv rays to destroy cancer cells in the body

Immunotherapy - This treatment boosts the immune system of the body so that it attacks the cancerous cells in the bladder.

Causes And Symptoms of Bladder Cancer

The kidneys may be a pair of small organs but they perform a very important function. Without the kidneys, it is impossible to filter blood and remove toxins from the body. One of the common problems associated with kidneys is the development of a kidney stone. This can be described as a hard, pebble like substance that is formed when urine contains high levels of certain minerals. Kidney stones vary in size and shape. Small stones may pass through the ureter into the bladder and out of the body with minimal discomfort. However, in some cases, a kidney stone can be as large as a golf ball. In such cases, it can block the urine flow and cause extreme amounts of pain as well as bleeding. In such cases, a doctor needs to be consulted as early as possible.

There are four different types of kidney stones.

Calcium Stones: This is the most common type of kidney stones. It is caused by excess calcium that is not flushed out with the urine.
Uric acid stones: Highly acidic urine can trigger the development of such stones. This may be caused by excessive consumption of meat, fish and shell fish.
Struvite stones: This is often formed as a side effect of Urinary tract infections. These stones may develop and grow rapidly.
Cystine stones: These stones are formed as a result of a genetic disorder known as cystinuria. This disorder causes an amino acid known as cysteine to leak into the urine.
Kidney stones are a fairly common occurrence. It affects both men and women but men have a higher risk of developing kidney stones as compared to women. Other risk factors that can influence kidney stones are:

Family history of kidney stones
Not drinking enough water
Obesity
Digestive problems
Recurrent UTIs
Gout
Bowel inflammation
Disease that causes blockage of the urinary tract
Certain medications such as diuretics or calcium based antacids
Once a person has been diagnosed with a kidney stone, this issue can recur. Treatment for kidney stones depends on the type of stones, size and location. In most cases, medication is prescribed to help break the stone down into smaller parts so that it can pass through urine. In extreme cases, surgery may be required. If not treated in time, it can cause severe pain, bloody urine, UTIs that can further lead to kidney failure and reduced kidney functioning.
Kidney stones can be prevented by drinking plenty of fluids and making a few dietary changes. Ideally, a person should have a minimum of 8-10 glasses of water a day. If you have a high risk of developing any type of kidney stones, reduce your sodium consumption and the amount of meat eaten.


Kidney Stones - Are They Really Common?

A large number of women visit the doctor for common ailments like involuntary urination or incontinence, which occurs due to weakening of the sphincter muscles around the urethra. An overactive bladder is an embarrassing as well as an annoying condition and it comes in forms like urinary urgency, urge incontinence, nocturia and frequency. Yes, there are solutions to this problem and the main solution that can be adapted is a change in lifestyle.

Imperative tips to follow to treat an overactive bladder

It is very important that the diet pattern be changed and food items as well as drinks that worsen the condition be avoided.
It is best to avoid spicy food, especially those that contain hot peppers. Citrus fruits like grapefruit, orange and tangerine must be avoided; tomato products and tomato paste must be avoided.
It is also best to avoid alcoholic beverages and even drinks that contain caffeine.
It is important to maintain a healthy diet. To improve bladder problems, it is obligatory that food products that contain more fiber are included in the diet.
These fibrous food items could include whole wheat bread, fresh fruits, cereals and beans. To maintain bowel regularity, it is very important that women follow a regular exercise program.
Women must take charge of their treatment and it is most important that before taking any medication, they must make behavioral modifications. It is important to record the input of the fluid consumed as well as to keep a check on the number of times they urinate. Women must not only maintain a healthy weight, but also quit smoking. Smoking cigarettes can irritate the muscles of the bladder and excess coughing can lead to leakage of urine. Non-irritating fluids that can improve the bladder condition can be taken 3-4 times in a day; so it is best to avoid beverages that are acidic or caffeinated. The techniques that would help you to control an overactive bladder can be learnt under the guidance of a doctor to decrease the urge to urinate.

Consult your doctor for medications to treat an overactive bladder. Some doctors even prescribe certain medications to treat an overactive bladder and these include anticholinergics. These drugs help to control the muscle spasms, which mainly lead to an overactive bladder. The most common anticholinergics recommended by doctors are solifenacin, oxybutynin, fesoterodine, propantheline and dicyclomine.

Overactive Bladder - Is There A Solution?

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