Glomerulonephritis is a disease that is caused due to inflammation of the small filters that are present within the kidneys or glomeruli. Glomeruli eliminate the excess waste, electrolytes and fluids from the blood, discharged through urine. A glomerular disease can be either acute or chronic. If the condition arises without a combination of any other disease, it is termed as primary glomerulonephritis. Secondary glomerulonephritis is characterized by diabetes or lupus (an auto-immune disorder) being at the root of the disease. Prolonged or severe inflammation can take a toll on the kidneys.


Causes-


Nephrotic syndrome can be primary, being a disease specific to the kidneys, or it can be secondary, being a renal manifestation of a systemic general illness. In all cases, injury to glomeruli is an essential feature. Kidney diseases that affect tubules and interstitium, such as interstitial nephritis, will not cause nephrotic syndrome.


Primary causes of nephrotic syndrome include the following, in approximate order of frequency:
Minimal -change nephropathy
Focal glomerulosclerosis
Membranous nephropathy
Hereditary nephropathies


Secondary causes include the following, again in order of approximate frequency:
Diabetes mellitus
Lupus erythematosus
Viral infections (e.g., hepatitis B, hepatitis C, human immunodeficiency virus [HIV] )
Amyloidosis and paraproteinemias
Preeclampsia
Allo-antibodies from enzyme replacement therapy


Nephrotic- range proteinuria may occur in other kidney diseases, such as IgA nephropathy. In that common glomerular disease, one third of patients may have nephrotic- range proteinuria.


Nephrotic syndrome may occur in persons with sickle cell disease and evolve to renal failure. From a therapeutic perspective, nephrotic syndrome may be classified as steroid sensitive, steroid resistant, steroid dependent, or frequently relapsing.


Treatment-
Whether one is suffering from acute or chronic nephrotic glomerular , with symptoms moderate or severe, the treatment lies in treating high blood pressure and other underlying conditions of the disease.
Water pills help control sweating, thus increasing the fluid flushed from the kidneys.
Statins reduce cholesterol level.
Blood thinners such as anticoagulants lower the risk of blood clots.
Corticosteroids regulate the immune system and ease the inflammation that results from kidney disorders.
Incorporating certain lifestyle changes such as opting for lean proteins, cutting on the intake of fat in the diet and consuming lesser amounts of salt can treat inflammation and swelling.
For kidney failure, dialysis can come to the aid in eliminating excess fluids and regulating hypertension.


Nephrotic Syndrome: Causes and Treatment

The kidneys are small organs that filter about 200 liters of water each day, removing out about 2 liters of toxins and wastes in a water medium as urine. In addition to maintaining the fluid levels in the body, they also produce hormones that regulate blood pressure, produce red blood cells, and play a vital role in maintaining bone health. Any problem with the kidney, infection or otherwise, can lead to its improper functioning, causing damaging results on the rest of the body organs.

While the bad news is that most diseases from infections to diabetes to hypertension and cancer have an adverse effect on the kidneys, there are signs that can be watched out for, which can indicate a problem with the kidneys and so further damage prevented. Read on to know some of the most common symptoms of kidney disease and how further progression can be prevented.

Change in urination process: Any change in the process of urination should be a warning for a test. It could be change in color or the appearance of the urine, painful urination, burning on urination, difficulty to start and stop a stream, or too frequent or infrequent urinations. These are usually the first symptoms of kidney disease and should be an alarm to get a kidney function test done. If you have hypertension or a strong family history of kidney disease, then getting a simple urine test to check optimal kidney function is definitely mandated. These could indicate conditions like infection, diabetes, kidney failure, or other conditions which can all be identified with further testing and then treated accordingly. The progress of the disease can be halted, which can help improve overall quality of life.
Fatigue, loss of energy: As noted above, impaired kidney function leads to other organs being affected and buildup of toxins in the body. There is also anemia which sets in due to decrease in red blood cells and therefore reduced overall energy levels, loss of sleep, and fatigue.
Swollen eyes, feet, and ankles: Reduced kidney function leads to fluid accumulation, sodium retention, loss of protein, which all lead to swollen eyes and ankles and feet. These are easy to identify and should ring a bell to get checked for kidney functions.
Muscle cramps: Improper electrolyte levels can affect muscle functioning, leading to painful cramps. Along with changes in the process of urination, this should be an indication of underlying kidney disease.
Keep a track of any above mentioned problems as they can help in saving not just the kidneys but all the vital organs.

Kidney Problems - 4 Signs to Watch For!

Kidney stones could be a cause for worry by the time they are not removed causing incessant and regular pains and disrupting normal life. The task is not finished even if you get them removed because what follows is a rigorous and disciplined routine that you must follow to maintain your health after the surgery is done. Diet plays a crucial role in negating the possibility of yet another stone accumulation. Here are a few diet tips that would be handy if you have got a kidney stones removal surgery done. 
 
Do's
1. To stay hydrated is the golden rule that you must abide by at all costs. It is advisable to drink at least 2-3 litres of water on a daily basis. Water prevents the formation of stones and would also help to eliminate any remaining residues of kidney stones existing in the system. 
 
2. Dairy products could be included but in diluted form. 
 
3. A fixed dietary routine is mandatory above all. The patient should be given meals at proper time intervals in small proportions. Heavy meals should be avoided at all costs. 
 
4. Foods rich in high fibre should be included in the diet. They help in bowel movement also. These include whole grain breads and beans. 
 
Don'ts
 1. Foods rich in oxalates and calcium should be kept at bay for at least a period of two months after the stone removal procedure is complete. Oxalates can lead to the formation of yet another stone which is far from desirable. The foods that fall in this category include:
-Green leafy vegetables like spinach, mustard and beet greens
-Cabbage, cauliflower, tomatoes
-Banana, mango, apricot, grapes
-Nuts like almond and cashew
-Alcohol
-Soft drinks
-Soda
-Caffeinated drinks like tea and coffee
 
2. Foods rich in sodium should be kept at bay for at least some time immediately after the surgery. 
 
3. Reducing the food intake that is high on animal protein. 
 
4. Do not eat stale food. 

5. Junk food should not even cross your mind. It is something which should be avoided for best results. 
 
These are generic guidelines that would help you to cope with post surgery care. However, there could be specific requirements depending from patient to patient. Therefore, it is advisable to get the guidelines by a doctor who will take into account the specificities of the case. Diet along with exercise is in most cases, the most effective combat to kidney stones. The trick however, is to not go overboard with either of them.

Diet Plan Tips After Kidney Stones Surgery - Eating Guidelines

One single kidney in place of two is a scenario which is often termed as solitary kidney.

Who has a solitary kidney?

Their body functions normally and are generally not unhealthy. This is also known as renal agenesis.
In some cases, people are born with two kidneys with just one of them healthy and fully functional. The other one does not function fully or partially. This condition is known as kidney dysplasia.
A person who had to undergo a kidney removal surgery (nephrectomy); such a surgery is conducted when a person has an infected kidney or diseased, malfunctioning/cancerous growths on the kidney.
A person who has donated a kidney to someone who required kidney transplantation.
What potential health risks does a person with a solitary kidney have?

Normally, a person born with a single kidney does not have any such potential health risks. They are generally healthy and lead normal lives.
Later in life, there may or may not be slight loss or degradation in the functioning of the kidney.
The life span of a person with a single kidney is normal. There is no apparent effect on the mortality rates.
What kind of special diet must a person with a single kidney follow?

There is no need of any such special diet for a person with a single kidney.
Normal healthy balanced diet with all the essential nutrients should suffice.
You must be careful about your animal protein intake and calcium supplements.
Drink sufficient quantity of water to remain hydrated all day and prevent the urine from turning acidic.
Controlled consumption of alcohol and caffeine is a must. It is also important to reduce the consumption of aerated drinks.
Exercises and Physical activities for a person with a single kidney:

A person with a solitary kidney can function like any other normal individual.
You may also participate in sports. However, you must take enough precaution to prevent injuries to your kidney. Proper padding and protection around your lower abdominal region and back is of utmost necessity.
You can hit the gym, run a marathon and nothing is impossible for you.

Living With Solitary Kidney - Things You Need to Know!

What is Diabetic Nephropathy?

Diabetic nephropathy (Diabetic Kidney Disease) is defined as the progressive damage to the kidneys caused by diabetes. It is characterised by the scarring of the glomeruli in the kidneys due to prolonged diabetes mellitus.

What Causes Diabetic Nephropathy?

Diabetes is a condition characterized by high concentration of blood sugar. Although the cause of Diabetes Nephropathy is not yet well defined, it is likely that the high sugar levels in the blood damage the blood vessels present in the kidneys that help to filter waste products, thus resulting in decreased kidney function and ultimately, kidney failure.

Not everyone with diabetes suffers from diabetic nephropathy. Although, factors that can increase your chances of getting diabetic neuropathy are-

Smoking

Poor control of blood glucose

High blood pressure

History of kidney diseases

What are the symptoms of diabetic nephropathy?

In the early stages, there may be no symptoms at all, but as the disease progresses, you may notice swelling in the extremities like your feet. Thus it is recommended to get your blood albumin levels tested on a regular basis. If it is diagnosed in early stages, the damage can be reversed. Other symptoms that can indicate damage to the kidneys are-

Severe malaise

Headaches

Nausea

Lack of appetite

Frequent voiding

Itchiness of skin

General feeling of illness

Diagnostic tests that can confirm diabetic nephropathy are-

Routine urine test (urinalysis) - Kidney diseases are detected by the presence of a protein in the urine called albumin and this condition is called albuminuria. Other parameters that must be regularly monitored are-

Blood pressure

Cholesterol levels in your blood

How can you treat/ manage diabetic nephropathy?

If this type of nephropathy is diagnosed in the early stages, the damage to the kidneys can be reversible. The key to managing diabetic nephropathy are-

Diet: Reduce the dietary intake of salt, phosphorous and potassium in the advanced stages.

Glycemic Control: Monitor your blood glucose levels regularly

Management of Hypertension: It is important to manage your blood pressure as it can have a direct effect on the coronary blood vessels which in turn pump blood to the various blood vessels of the body

Renal Replacement Therapy: In chronically ill patients, renal replacement therapy is the best option. This can include haemodialysis (a procedure to flush out toxins from the blood, such as urea), peritoneal dialysis or ultimately renal transplantation.

Diabetic Nephropathy - Causes, Symptoms and Treatments

Bladder cancer is characterized by irregular growth of abnormal tissue (tumor) on the lining of the bladder. This type of cancer may spread to the surrounding tissues or other body parts as well.

What are the causes?

Bladder cancer can be caused by environment-related factors and smoking. In fact, smoking tobacco is one of the major causes of bladder cancer around the world. The chemicals present in tobacco can irritate the bladder lining which ultimately leads to bladder cancer. It may also be caused by continuous exposure to chemicals such as dyes or leather dust and radiation. These chemicals tend to cause unusual changes in the cells of the bladder lining and causes cancer in the bladder.

It can also be caused by modifications in the dna in the cells of the bladder which may impair the functioning of the cells in the body. This can cause mutations in the bladder resulting in cancer.

What are the symptoms?

1. Presence of blood in the urine, often painless

2. Feeling of pain while passing urine

3. Back pain

4. Excessive urination

5. Infections in the urinary tract

6. Lower leg swelling

7. Pain in the bones, especially in the pelvic area

8. Weight loss

Treatment options

Treatments for bladder cancer depend on the stage of the cancer. The various treatment choices are:

Surgery - In some cases, these cancers are surgically removed by a surgeon. A type of surgery used is transurethral resection of bladder tumor (turbt) where the cancer cells are destroyed with laser by passing a thin fiber into the bladder.

Chemotherapy - In this method, medications are used to target and destroy cancer cells.

Radiation therapy - Radiation therapy uses rays such as x-ray or uv rays to destroy cancer cells in the body

Immunotherapy - This treatment boosts the immune system of the body so that it attacks the cancerous cells in the bladder.

Causes And Symptoms of Bladder Cancer

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