Causes and symptoms of acute tubular necrosis

Damage or destruction to tube-like structures known as tubules in the kidneys can bring about the development of acute tubular necrosis (ATN) and subsequently, acute kidney failure.

What causes acute tubular necrosis (ATN)?

A lack of supply of oxygen to the cells in the kidney is the most common cause of this condition. The reason as to why oxygen may not reach the cells and tissues of this organ could be restriction or blockage of the pathways. When this happens, the kidneys get damaged. Dehydration is the most important cause of ATN which may be because of loose motions, vomitings, heat stroke etc.

Health conditions such as diabetes, heart attack, and stroke can bring about a decrease in blood flow to the organs resulting in ATN and death of cells. Similarly, the presence of toxic substances in the blood can also lead to tubules damage and change the way the cells function in the tubules.

Other causes that may lead you to develop ATN may be medications, radiology dyes, anesthetics and chemicals that cause your body to react adversely.

In addition to these causes, a number of factors can put you at risk of ATN and there are:

- An injury to the body, more specifically your kidneys can cause clotting of the blood vessels
- An adverse response to blood transfusion
- Instances of septic shock can slow down blood flow to the organs
- A major surgery that can interrupt blood supply to the organs

What are the symptoms of the condition?

The symptoms associated with the condition can vary depending on the severity of the problem.

You may experience:

- Troubles in waking up
- Drowsy feeling even during daytime
- Feelings of lethargy
- Feelings of excessive thirstiness
- Problems with urination
- Fluid retention problems
- Instances of confusion
- Feelings of nausea



Can Acute Tubular Necrosis Cause Kidney Failure?

There has been an intense debate, which is in the loop for years and has been raging back and forth regarding the deficiencies of a vegetarian diet versus the perils of a non-vegetarian one. This heated debate is both accurate as well as unfounded. Probably, that s the entire reason it is still a debate. In fact, if you look into the diet of both groups, you will be able to identify the fact that, there is a space for healthy living in both.

Vegetarian Diet

In a vegetarian diet, the food intake of a person is confined to a large variety of foods derived from plants along with milk and dairy. And, any form of meat and products derived from animals are completely avoided.

Pros

Vegetarians have been noted to consume lesser amount of proteins, but they do not suffer from problems related to a high protein diet, such as osteoporosis (characterized by brittle and weak bones) and kidney failure.
The diet includes high level of antioxidants such as vitamin E & C as well as carotene, which is available in vegetables and fruits.
Additionally, they consume less amount of saturated fats.
Cons

Deficiency of vitamin B12 is common amongst vegetarians, as it is mainly available in meat, eggs and fish. Deficiency of vitamin B12 can yield rare symptoms such as increased fatigue, shortness of breath and a temporary loss of body balance.
Lack of protein, as stated above, along with iron and zinc deficiency is also common. 
Symptoms of protein deficiency can be troublesome and include signs like

Sluggish metabolism
Loss of body muscles (as the body tries to derive the regular protein intake from your muscles, thus making them weak),
Trouble gaining or losing weight
Persistent fatigue
Longer healing time in case of wounds and injuries
Pain in joints
Drastic changes in blood sugar level that might result in diabetes
A weak immune system makes you vulnerable to all kinds of diseases.
Non-vegetarian Diet

A non-vegetarian diet includes all forms of plant foods as well as foods and by-products that are derived from animals, such as poultry, fish, meat, etc.

Pros 

Vitamin B12 is present in adequate level since they are derived from sources such as meat, eggs and fish. Adequate intake of proteins is never an issue for  non-vegetarians
Cons

Meat products are loaded with saturated fats, which increase the risk of heart diseases. Studies have shown that people consuming non-vegetarian diets:
Have shorter lifespan and are more vulnerable to chronic diseases.
Tend to develop diabetes, heart diseases and hypertension.
Usually non vegetarians eat less amount of vegetables and fruits than what is recommended.  
If you wish to discuss about any specific problem, you can consult a Dietitian/Nutritionist.

Vegetarian vs Non Vegetarian Diet - Which is Better?

You're said to suffer from the problem of acute kidney failure if your kidneys suddenly stop working and lose their ability to eliminate waste materials including excess fluids and salts from the blood. The condition usually develops quickly over a few days or even a few hours. When this happens, waste materials accumulate in your blood, disrupting the chemical balance of your bloodstream.

So, what causes this problem?

Acute kidney failure can occur because of any one of these reasons:

1. A drop or slowdown of blood flow to the kidneys - Adequate blood circulation to the kidneys is of great importance as without it the kidneys may end malfunctioning. If blood flow to the kidney is hampered, a part of or the entire kidney may die. You may suffer from acute kidney failure if blood flow to the kidneys gets impaired due to conditions like

Heavy blood loss
Sepsis (body's inflammatory reaction to an infection, which can bring about organ failure, tissue damage, and death)
Injury
Use of certain drugs
Dehydration
Burns
Heart disease
2. Urinary obstructions - A sudden blockage that hampers your kidney's ability to eliminate urine can also bring about acute kidney failure. When this happens, it leads to a build up of toxins in the body, causing an overload of the kidneys. Conditions that bring about this urinary obstruction include:

Cervical cancer
Colon cancer
Bladder cancer
Kidney stones
Enlarged prostate
Prostate cancer
3. Disease within the kidneys - Even instances of clotting within the blood vessels of the kidneys can lead to acute kidney failure. This is because if the movement of blood cells within the blood vessels gets hampered, kidneys are not able to filter out toxins from the body. The conditions and diseases that may cause clotting, and subsequently damage to the kidneys include:

Scleroderma (an autoimmune disease that affects connective tissues and skin)
Build-up of cholesterol deposits
Glomerulonephritis (an inflammatory condition of the kidney's ball-shaped structures called glomeruli)
Hemolytic uremic syndrome (a condition that occurs due to untimely death of red blood cells)
Lupus (a disorder of the body's immune system that brings about damage to the body's own organs and tissues)

3 Causes of Acute Kidney Failure!

Needless to say, your kidneys play an incredibly important role in filtering waste from your blood, and therefore maintain healthy functioning of the body. Blood pressure, production of red blood cells, and electrolyte balance, all of these are regulated by the proper functioning of the kidneys. Kidney failure causes too much build-up of waste nitrogen products,acids and/or excess fluid,which causes major cardio respiratory problem to the patient.
Symptoms-

Shortness of breath 
A reduced amount of urine
Swelling of your legs, ankles, and feet
Excessive drowsiness or fatigue  
Confusion
persistent nausea
Pain or pressure in your chest
Seizures
Coma 
Inability to properly remove potassium that runs in the bloodstream can lead to irregular heartbeat and ultimately, death that is sudden and unforeseen.

How can it be treated?
The causes of kidney failures are many and the key to treat them is to correct the underlying cause first. Chronic kidney disease, however, has no cure. Treatment generally comprises measures that aid in controlling symptoms and signs, reduce complications, and slow down the progression of this disease. Despite efforts to treat the cause, the condition might keep worsening and there is little to guarantee the fact that complications will not arise. This is precisely why it is of utmost importance to opt for examinations at regular intervals so that you may ascertain if your disease has remained stable or worsened.

End-stage of Kidney disease 
In the case that your kidneys are unable to keep up with fluid and waste clearance as is normally expected, then there s a good chance that you have developed a near-complete or complete case of kidney-failure, and are afflicted by end-stage kidney disease. If this is indeed the case, then you have two options to resort to:

Dialysis: This helps remove the extra waste products that the kidneys fail to do. In haemodialysis, fluid and waste filtering takes place with the aid of a machine that drives these excesses from the blood. In peritoneal dialysis, catheters are employed to rid the body of the accumulated waste products.
Transplant: Kidney transplants involve a surgical placement of a healthy kidney in your system from a compatible donor, either living or dead. Medications will be a necessity since the body has to be prevented from rejecting this new organ.
You may also opt for treating the condition with conservative measures in case you don t want to resort to the aforementioned procedures.

Kidney Failure - What Should You Know About it?

A diseased kidney is one that has lost its ability to carry out the filtration process in a proper manner. This process of filtration usually sends the waste and toxins out of the body in a routine manner. In such cases, a kidney disease manifests which requires a number of treatment measures. Dialysis is something that enters the treatment plan at a later stage as chronic early stage kidney disease can remain in the patient s body for many years. When the kidney function comes down to 15%, then most doctors recommend the start of dialysis which is basically a process that removes the excess waste and fluid from the blood. This can be a process that will leave the patient fatigued and in a mental state that is not exactly stable and positive at all times. It is common to see dialysis patients battling depression due to the chronic nature of the treatment as well as the low chances of recovery.

So, let us find out how dialysis patients can cope with depression.

    Professional Help: Depression is said to be like a common cold when it comes to mental diseases. The state of a person s body can very well affect the balance in his or her mind and lead to depression. Starting from pressing circumstances to hormonal changes as well as chronic ailments, depression can affect people due to a number of reasons. Dialysis patients who are undergoing depression must consult a professional specialist like a psychiatrist who will help the patient understand and cope with the situation with the use of therapy based counselling.
    Medication: The patient can also be given medication that will prevent the build up of unnecessary stress by blocking the production of those hormones that result in a negative state of mind. This medication must be prescribed after speaking the patient s nephrologist about what kind of medication will suit the patient specifically.
    Psychotherapy: Long term psychotherapy is also known as talk therapy that can help the psychiatrist or clinical psychologist in talking the patient through the problems. Besides giving the patient the scope and platform to air out the problems and reach solutions regarding normal day to day functioning despite the troubles, this kind of therapy also aims at equipping the patient with a better perspective and improved attitude.

While going through this kind of therapy and medication, it is important to keep a team of nephrologists and psychiatrists in the loop so that the patient may reach out at any time in order to avail help in the most trying situations. This will give a blanket of security to the patient as well.

3 Ways a Dialysis Patient can Cope with Depression

The mere thought of biting into a chilled watermelon or sipping chilled watermelon juice during summer is a refreshing thought. What many do not readily realise is that not just they are not just a refresher, but they are also loaded with multiple health benefits. Another surprising fact is that they have been in use since 5000 years ago and are referred to in ancient literature. There are about 300 varieties and are easily available during summer.

Many may think that watermelon is loaded with water. However, there are also multiple compounds including vitamins and minerals; vitamins C, A, B1, B5, and B6; minerals like potassium and magnesium, and compounds like carotenoids and lycopene. These have multiple benefits on the health and so watermelon can be consumed without any second thought in abundance.

Read on to know some of the wonders of this melon.

Hydration: One of the best remedies to avoid the ill effects of summer is to improve hydration levels, and there could be no better way to do this than with watermelon (eat it or drink it!) It is 92% water, and therefore leaves you refreshed and rejuvenated.
Heart health: Lycopene helps reduce cholesterol, reduce thickening of artery walls, and reduces oxidative stress. The various minerals and vitamins also add to the heart health qualities of watermelon. The citrulline in it also increases nitric oxide level in the body, which expands or dilates blood vessels and improves blood pressure.
Anti-inflammatory benefits: The lycopene and vitamin C reduce the levels of C-reactive protein which are responsible for inflammation. The antioxidant levels also lower inflammation, thereby reducing the onset of degenerative diseases like Alzheimer s.
Eye health: Watermelons, through their anti-inflammatory effects, reduce the onset of age-related macular degeneration. Those who already have it can also see the delayed progression of the condition, thereby prolonging vision loss.
Muscle soreness: Those who have muscle soreness should reach out for a slice of watermelon to get instant relief from this soreness. Watermelon also improves exercise endurance and performance, and the added benefit on the heart also improves exercise tolerance.
Skin and hair benefits: These benefits come from multiple sources in the melon. The vitamin A helps improve skin regeneration, vitamin C helps collagen formation and improved skin tone. Lycopene and beta-carotene help control the damage caused by sun exposure and pigmentation.
Digestive benefits: The very nature of watermelon almost completely water and high fibre directly benefits the stomach. It cleanses the stomach and promotes bowel movement. Not just the red portion, even the rind and seeds are beneficial as there is a lot of citrulline and chlorophyll which are also healthy.

Watermelon - One Fruit, Many Benefits!

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