Cancer like most other diseases has the best rates of recovery with early detection and intervention. As there are no regular health screenings for blood cancer, only the awareness about the early warning signs can save your life. November is designated as the Lung Cancer Awareness Month, to ensure every individual is equipped to fight against lung cancer right from the start. Here are 4 vital facts you must know to win your fight against blood cancer.
Lung cancer is also known as pulmonary carcinoma or cancer of the lung. It occurs when DNA mutations develop in the cells/ tissues of the lungs leading up to uncontrolled growth in the tissues of the lung. By far, it is known to be the most common cancer in Asia.

1. Type: lung cancers can present as one of the following types: 

Non-Small Cell Lung Cancer (NSCLC): Most common type of lung cancer and constitutes nearly 85% of all lung cancers. The sub-types of NSCLC are as follows:
Large cell carcinoma
Squamous cell carcinoma (SqCC) (Epidermoid)
Adenocarcinoma   accounts for majority of the NSCLC.
Small Cell Lung Cancer (SCLC): It is also known as oat meal cancer and tends to spread (metastasize) quickly. This constitutes about 15% of the lung cancers.
Mesothelioma: It is a rare cancer that develops in the mesothelial cells of the pleural or peritoneal surfaces. It usually arises in the pleural membrane lining the lungs, known as pleural mesothelioma. One that arises from the peritoneum is called the peritoneal mesothelioma and the one that arises from the pericardium is known as pericardial mesothelioma. Lastly, it can also arise from the tunica vaginalis known as testicular mesothelioma. People working with or prior exposure to asbestos are mostly at risk of developing mesothelioma. The latency period between time of exposure and development of mesothelioma can be somewhere between 20 to 40 years. Maximum of the patients who develop mesothelioma are men.
2. Gender: It affects the male populace predominantly. It is more common in men than in women and in those of lower economic status. However, the incidence of lung cancer, in women too, is on the rise of late.

3. Etiology: Cigarette/ Tobacco smoking remains the most important cause of lung cancer accounting for 85   90% of the cases. Incidence/ risk is proportionate to the number of cigarettes smoked irrespective of the age. Also, environmental toxins including smoke from burning black tar, exhaust gases from automobiles etc. too contribute actively to various lung diseases including cancer. People working in asbestos manufacturing factories who are exposed to asbestos dust are also likely to get lung cancer. Tuberculosis too is an additive risk factor. Again, people who have received ionizing radiation especially to treat Hodgkin Lymphoma or other malignancies also run the risk of developing lung cancer. Above-mentioned causes apart, genetic factors may also play a role.

4. Features: Lung cancer clinically presents in the following ways mainly. Signs & symptoms of malignant mesothelioma are as enumerated below

Difficult/ labored breathing (Dyspnea)
Chest pain
Palpable chest wall mass
Discordant chest wall expansion
Weight loss (Cachexia)
Loss of appetite (Anorexia)
Night sweats
Signs & symptoms of non-small cell lung cancer (NSCLC) are as enumerated below. Majority of patients are symptomatic at diagnosis

Chronic cough
Difficult/ labored breathing (Dyspnea)
Chest pain
Blood stained sputum (Hemoptysis)
Hoarseness
Weight loss (Cachexia)
Loss of appetite (Anorexia)
Weakness
Bone pain
Pleural or pericardial effusion
Superior vena cava syndrome
Brachial plexopathy
Neurologic pain
Hypercalcemia of malignancy
Signs & symptoms of small cell lung cancer (SCLC) are as enumerated below

Symptoms as per the points 8   18 depicted above for NSCLC are applicable for SCLC as well. Additionally, patients suffering from SCLC may have:

Fever associated with chest infections like bronchitis/ pneumonia that refuse to go away or keep coming back
Horner syndrome
Paraneoplastic syndromes including encephalitis/ sub-acute sensory neuropathy, hyponatremia, acromegaly, cancer associated retinopathy, ectopic corticotropic syndrome etc all.
5. Screening: is generally recommended for asymptomatic/ symptomatic populations as surveillance for high-risk individuals   who are either current or former smokers (quit smoking within the last 15 years) have at least a 30 pack-year smoking history and those who do not have any prior history of lung cancer. The goal of screening, as usual, is to be able to detect & diagnose lung cancer at an early stage which is potentially curable. It is mostly radiologic with a low dose helical computed tomography (CT) scan being more effective in detecting early-stage lung cancer than a chest radiograph can.

6. Diagnosis: Abnormal blood test results may be indicative of malignancy, but a follow-up imaging/ biopsy is always the gold standard for an accurate diagnosis. Following are the diagnostics employed mainly:

Blood: Hb may be low, TLC, ESR and polymorphs increased. Adenocarcinomas are likely to express thyroid transcription factor 1 (TTF-1) or carcinoembryonic antigen (CEA). On the other hand, mesotheliomas are likely to express Wilms Tumor -1 (WT-1) protein and Calretinin.
Imaging: Thoracoscopy, Bronchoscopy, X-Ray, CT Scan etc all. Positron Emission Tomography (PET) / CT scan and Magnetic Resonance Imaging (MRI) scan help detect metastasis if any.
Biopsy: It clinches the histologic diagnosis and the nature of the disease.
7. Treatment: Conventional treatment includes surgery, chemotherapy and radiotherapy as contextually appropriate. Simultaneously, an adjunctive or integrative naturopathic treatment with suitable complementary & alternative medicines (CAM) too can help improve clinical outcomes and facilitate recovery as would be feasible contextually.

8. Prognosis: Preventive measures, earlier diagnosis and right early treatment are key for effective therapeutic management & better prognosis. Like most other cancers, the chances of cure for early-stage lung cancer are more. The cure/ recovery chances are influenced by the grade, stage of cancer, recurrence and the patient s general health & vitality etc all. The primary determinant of prognosis in NSCLC is the stage at which the cancer is diagnosed. For non-metastatic cancers, however, it is the nodal status that determines the stage and hence the prognosis.

9. Prevention: Rightly said, prevention is always a better choice. Cigarette smoking is to be avoided by all means as it is the single major cause of lung cancer. Even exposure to cigarette smoke (passive or secondhand) is also an established cause of lung cancer and is known to increase the risk of lung cancer in non-smokers as well. Preventing exposure to secondhand smoke can be helpful in decreasing the incidence and mortality of primary lung cancers. Above-mentioned apart, other important risk factors such as exposure to ionizing radiation, environmental carcinogens like smoke from burning black tar, exhaust gases from automobiles, outdoor air pollution, and occupational exposure to asbestos, arsenic, beryllium, nickel, cadmium, chromium etc all too are known to increase the risk for lung cancer and mortality thereof. In fact, cigarette smoking is known to potentiate the effect and hence the lung cancer risk of many of the above-mentioned carcinogens, multi-fold, in smokers. Thus, either eliminating or reducing the exposure to the above-mentioned carcinogens can lead to a decrease in the risk of lung cancer and incidences thereof. Furthermore, randomized clinical trials indicate that high-intensity smokers (only) who take supplementation of beta-carotene have an increased risk/ incidence of lung cancer. Vitamin E supplementation, on the other hand, does not affect the risk of lung cancer as indicated by the trials. 

In case you have a concern or query you can always consult an expert & get answers to your questions!

Lung Cancer Awareness Month - Lung Cancer In Nutshell!

Myth: COPD is an incurable chronic lung disease mainly affecting the aged people (above 60 years).
Fact: There is no denying the fact that COPD is indeed a chronic disorder that severely affects the lungs and its functioning. However, with timely diagnosis and treatment, the condition and the deleterious consequences can be managed and controlled significantly. Since COPD triggers breathing problems (the airflow from the lungs gets obstructed), the use of bronchodilators, oxygen therapy or corticosteroids can be highly beneficial. Though COPD is rare among young adults, the condition can affect people in their late 30's or early 40's as well.

Myth: COPD only affects people who smoke.
Fact: Smoking is one of the triggers for COPD, but the condition can also affect people who have never smoked in their lifetime. Factors such as neonatal chronic lung disease or prolonged exposure to substances that cause lung irritation and damage (toxic industrial fumes and chemicals) can play a pivotal role in triggering COPD. COPD can also be a genetic predisposition.

Myth: People with COPD should avoid exercise and physical activities.



Fact: Mild to moderate exercise (especially breathing exercise) are indeed helpful and go a long way in the effective management of COPD. Exercising regularly (for 20-30 minutes or as the doctor recommended) help to lower the blood pressure and improve the circulation that provides fruitful results for people with breathing problems. However, doctors do advise people with shortness of breath to avoid strenuous exercise.

Myth: COPD only affects the lungs.
Fact: With time and left unmanaged and untreated, COPD acts as a catalyst making a person more susceptible to heart ailments. In some cases, the condition can also trigger depression and anxiety.

Myth: In the case of COPD, giving up on smoking will not produce any positive results.
Fact: Giving up on smoking may not help to reverse the damage that has already been caused by COPD. However, quitting smoking along with proper medications and lifestyle changes does help to control the condition better. In some instances, there were also significant improvements in the associated symptoms (such as shortness of breath, fatigue, wheezing, a chronic cough).

Myth: COPD is another name for Asthma.
Fact: Many people confuse COPD with Asthma. Though some symptoms may appear identical (such as wheezing, shortness of breath), the conditions are different and so are their treatments. In case you have a concern or query you can always consult an expert & get answers to your questions.

COPD - Are You Aware Of These Myths & Facts?

Coughing during the night can really wreak havoc for your sleep and cause inexplicable discomfort in the throat and chest region. Thankfully, you can manage it by soothing your tickling throat as well as sensitive airways before you go to bed at night. 

Drink herbal tea: A mugful of non-caffeinated tea mixed with a teaspoon of honey before going to bed can help you to a considerable extent. This is because any warm liquid has the power to break down the formation of mucus in the throat region and with a bit of honey, the herbal tea becomes even more powerful.
Try to sleep in an inclining position: Gravity is your greatest enemy while combating night-time cough. When you lie down flat on your back at night, all the mucus and dust particles, which you have swallowed all through the day, would accumulate in the throat area and aggravate it making more cough. But you can easily defy gravitational force by piling up some pillows and prop yourself on them while sleeping. You may also keep a wooden block of 4 inches height under your head, which would keep the acids in the stomach so that they don t come up to irritate your throat.
Make sure you use the steam cautiously: When your airways are dry, it can make you cough harder. Therefore, you may find relief if you take a warm shower or a bath before going to bed. But you have to be sure that you don t have asthma as steam can prove harmful for you.
Check the level of humidity: Humidifiers are known to soothe the problem of persistent coughing when the surrounding air is dry. But too much of moisture during the night can also make you cough. This is because dust mites, mold and other allergens thrive well in the damp air and they could conspire to make your cough even worse. So, pick up a cheap hygrometer from a hardware store and see that the humidity level stays within 40 to 50 percent.
Equip yourself at night: Keep all the things from drops to water to cough syrup or anything that soothes coughing at your bedside so that you can help yourself in case you wake up in the middle of the night and start coughing.
By following these few tips every day, you can manage the night time cough and have a good night s sleep without any interruptions.

Night Time Cough - 5 Tips to Manage it

Tuberculosis or TB is a highly contagious airborne disease, which is caused by Mycobacterium tuberculosis. It typically affects your lungs and is characterized by the formation of greyish, hard nodules or tubercles.

Pathology of Tuberculosis

Diagnosis of the disease depends essentially on identifying the bacteria from the tissue. Methods of diagnosis usually include the following  

Skin Test   The most common test for detection of tuberculosis is the skin test. During the procedure, a small dose of PPD tuberculin is injected onto the skin of the forearm. The injection site needs to be monitored after a couple of days. Swelling in the forearm, usually, a hard, red bump could mean that you have contracted tuberculosis.
An X-ray of the Chest   Chest X-ray can reveal calcification, cavitations, and nodes in the upper lobes
Sputum Cultures and Smears   These are mostly used to detect pulmonary tuberculosis. Three specimens of sputum early in the morning are collected on three separate days. The specimen is prepared on a slide and stained with an acid-fast dye before being observed under the microscope. The slide may show the characteristic AFB or acid-fast bacilli.
Gastric Aspirates Test   This involves placing a tiny nasogastric tube in the abdomen early in the morning and gastric contents are suctioned and processed for culture and smears.
Lymph Node Biopsy   The procedure involves removing an enlarged lymph node and culturing a portion of it. The remaining section is sent for staining and examined under a microscope.
Biopsy   Biopsy is conducted when an abnormality develops in the airways during bronchoscopy. This involves threading a thin wire through the bronchoscope and attaching tiny biopsy forceps to its end in order to remove multiple tissue samples from the bronchi. The samples are sent to the laboratory for complete analysis.
Treatment of Tuberculosis

Studies show that in the majority of cases, patients were cured with the help of the right medication. The type and dosage of antibiotic treatment precisely depend on factors like   the patient s age, health condition, and potential resistance to certain drugs, whether the disease is active or latent, and the infection site.
Patients with latent TB may require one type of antibiotic, while those having active TB   particularly MDR TB   are often prescribed multiple drugs for about 6-9 months.
Patients who received proper treatment on time have shown vast improvement on the health aspect. After a few weeks of undergoing treatment, you might be tempted to quit taking your TB medications, but it is important that you complete the full treatment course. Skipping doses may allow the bacteria to become drug-resistant, leading to tuberculosis that is more severe and difficult to cure.



Tuberculosis - All You Must Know!

The festival of Diwali is greeted with great pomp and splendour and along with the regular festivities, the pollution levels in the air also rise due to the ritual of bursting fire crackers. In an analysis, the rise of harmful pollutants such as sulphur dioxide and nitrogen dioxide seemed to reveal a disturbing outcome.

The rise in pollution during Diwali affects you in the following ways:

The PM (particulate matter which is smaller than 2.5mm) enters your lungs and bloodstream and has several health impacts including chronic respiratory symptoms such as painful breathing and shortness of breath which might cause premature death.
High sulphur dioxide levels in the air during Diwali also lead to inflammation of air passages and causes complications in respiration.
A compound called  strontium  found in the atmosphere multiplies by 120 times during the festival and causes bone damage and blood clotting ailments.
Firecrackers contain heavy metals which are toxic to the human body and the amount of magnesium in the air goes up by 22x, which poses a significant threat to all forms of life.
The noise pollution also rises during the festival and in extreme cases, can permanently damage one s hearing.
However, there are a few measures you can undertake to steer clear of the excessive pollutants present in the air:

Limit the amount of time you spend outdoors even while exercising. This is because the air remains contaminated, days after all the festivities get over and the pollutants take a very long time to dissipate.
Even on the road, drive with the windows of your car rolled up to avoid intake of adulterated air and use a face mask if you are a two-wheeler rider.
Plant a lot of green plants inside your house as they purify the air you are breathing and ensure a supply of fresh oxygen.
Install an air purifier in the room to make sure you breathe in fresh, uncontaminated oxygen when you sleep. The air purifier will also help in lessening your respiratory complications.
Also, in case you notice any respiratory or breathing problem, it is advisable that you consult a pulmonologist, to rule out serious health issues. 

Diwali - How the Rise in Pollution Level Affects Your Health?

Most people know all about Asthma, how dangerous it is and most importantly, with the rising levels of pollution and irritants how people are getting affected by it all over the world. Just like famous events, incidents and festivals have their special date in the calendar, May 1 apart from being the International Labour Day, holds another significant stance worldwide. As it is celebrated as the World Asthma Day. This day marks the initiation of the Asthma awareness campaign worldwide.

Understanding Asthma in brief

Asthma is a long-term respiratory condition, in which the airways of the human system may unexpectedly and suddenly narrow, often in response to an allergen, cold air, exercise or emotional stress. Common symptoms include wheezing, shortness of breath, chest tightness, and coughing.

Why is Asthma Day important?

World Asthma Day is celebrated every year on the first Tuesday of May. This year it falls on 1st May. The day is celebrated to spread awareness about Asthma and how people all over the world can spread it amongst their families. Therefore to commemorate the event and educate the students in school and parents at home, World Asthma day was commenced. The aim of this campaign is to make people understand the types of Asthma that can affect them and immediate safety tips so as to ensure that the severity of the disease can be curtailed. 

Things to keep in mind about Asthma

All over the world, there are several people who do not opt for Asthma treatment and that proves to be a fatal mistake later on in life. Chronic Asthma disease can be easily prevented by a simple treatment in the initial stages. People who suffer from Asthma often face chronic attacks if they forget to carry their inhaler and different kinds of allergies are also very fatal for asthma people.

Things that can trigger Asthma in people

Dust 
Pollens
Gastroesophageal Reflux
Pet Dander
Certain foods 
Exposure to chemicals 
Excessive physical activity 
Stress 
39-50% Of Sinusitis patients have Asthma also 
Extremely cold conditions
Signs someone is suffering from Asthma 

Persistent coughing
Difficulty in breathing
Wheezing 
Tightness in chest
Diagnosis and severity are established by a simple air blowing test known as Spirometry.

Chest X-ray and Sinus X-ray Help 
Serum IgE a blood test tells about type and severity
Severe cases may require special blood test known as Arterial Blood Gases to look at blood oxygen and carbon dioxide.

Sheet anchor of therapy is the inhaled medication to dilate airway and to reduce inflammation. The dose being in microgram dose is harmless and delivered to the site of the problem.  New drugs known as Omalizumab and Benralizumab are approved for specific nonresponding patients with severe asthma.

Prevent asthma from being harmful

Asthma is a chronic disease can stay for the rest of someone's life. So on this World Asthma Day make sure that you know how it can be treated and prevent the disease from harming someone you love. Here are some treatment tips.

First get to know more about asthma and become a partner with the doctor to carry out treatment for a long time period.

Be aware of the allergens that may trigger asthma and prevent them from coming in contact with the person.

Make sure to keep the doctor updated regarding the status of a patient's condition and for any sign of potential risk.

If a loved one is suffering then ensure that they lead their life as per the guidelines shared by the doctor, in order to prevent any risky situation. 

So here are the important things that you should be knowing about asthma. And, in case you notice any of the symptoms mentioned above, one should immediately contact their doctor. On this World Asthma Day be aware of the disease and keep the people safe who are suffering from it. Stay Healthy!

World Asthma Day - Spreading Awareness Is Important!

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