Cystic Fibrosis is a genetic disorder that is known to affect some of the vital organs of the body including the lungs, digestive system to name a few. For long it was believed that cystic fibrosis affects a person in their childhood. However, various research and studies suggest that adults are also susceptible to this inheritable disorder. In this article, we will discuss the cause and symptoms associated with cystic fibrosis.

Cause
The epithelial cells that line the stomach, nasal cavity and lungs, are responsible for the production of the digestive fluids, sweat, tears, mucus. The Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) gene codes for a protein called the CFTR protein. The CFTR protein, a membrane protein plays a pivotal role in transporting the chloride ions of the epithelial cells inside and out of the cell. This regulation of the chloride ions goes a long way in ensuring that the mucus produced is free-flowing and thin.

In the case of Cystic Fibrosis, the CFTR gene that codes for the protein undergoes a mutation. With the CFTR protein unable to perform its function, sticky and thick mucus builds up and clogs some of the major systems of the body including the digestive system, reproductive, and respiratory system. There is also a higher salt content in the sweat of the affected person.

For a person to be affected by cystic fibrosis, he/she must inherit a copy of the mutated CFTR gene from both the parents ( Autosomal Recessive Disorder) at birth.

Symptoms
The symptoms associated with cystic fibrosis depends on the organs and systems affected.

The thick mucus formed can clog the digestive tract resulting in incomplete absorption of the essential nutrients from the food. This may have an impact on the overall growth and development of the body.
- There may be stunted growth or no weight gain.
- The stool may appear greasy and foul smelling. Some may also suffer from constipation.
- Newborns and infants may suffer from an intestinal blockage.
Cystic fibrosis, left unattended can lead to diabetes, intestinal blockage or obstruction.
- The mucus can also block the bile duct triggering a host of problems including liver disorders.
- At times, the obstruction or blockage can occur at the junction where the large and the small intestine meets (Distal intestinal obstruction syndrome).
The thick mucus can also affect the lungs and the respiratory system by blocking the tubes that act as a passage carrying the air inside and out of the lungs. As a result,
- A person may suffer from lung infections frequently.
- There may be difficulty in breathing, stuffy and blocked nose, or wheezing.
- Some people may also suffer from a chronic cough with a thick sputum.
Left untreated the complications can worsen resulting in

Nasal polyps, Chronic infections, Hemoptysis (there is blood while coughing), and Pneumothorax (air fills up in the space bifurcates the chest wall from the lungs).

In severe cases, there may be a respiratory failure.

Cystic fibrosis can also trigger fertility problems (both in males and females).

Cystic Fibrosis- Causes and Symptoms!

Tuberculosis or TB as it is commonly known in medical circles is a bacterial infection commonly affecting the lungs. While there are some countries in the world, where TB is more common, anybody can develop TB if they are not very healthy. The TB bacteria spreads through the air. While some people's immune system would be able to fight the disease back; some people who have risk factors, the disease may continue to develop and present with symptoms. 

So, a person can develop TB in two circumstances:

Exposure to TB
Visited a country where TB is very common
Spent time with a person who is infected with TB
Exposure to crowded places like a market or a healthcare facility where TB virus is present
Weakened immune system
Be HIV infected
Weak immune system due to long-term use of steroids
Chronic diseases like diabetes, malnutrition, end-stage kidney or liver disease, cancer, etc.
Extremes of age (children whose immune system is not fully developed, elderly whose immunity is weakened)
Chronic smoker, IV drug abuse, and/or alcohol user
Repeatedly exposed to TB bacteria in the last two years
Had TB bacteria, but not identified or treated
Drug therapy like chemotherapy, long-term use of steroids, auto-immune disease treatments, etc.
Signs and symptoms of TB: 

If you are at risk, it is also suggested that you know the early warning signs and symptoms of TB. TB most commonly affects the lungs and is known as pulmonary tuberculosis. Watching out for these helps in early diagnosis which can both help arrest the condition in the early stages and improve prognosis.

A persistent cough which lasts for more than 3 weeks
Pain in the chest worsened with coughing
Presence of blood in the sputum
Generalized and extreme weakness or fatigue
Unexplained weight loss
Loss of appetite
Fever and chills
Profuse sweating at night
If a person has TB bacteria in the system but does not feel sick and does not have the above systems, then it means that the person is not actively infected. This person also cannot spread the disease to another person. However, when immunity is weak, this can develop into an infection. In a country like India where tuberculosis is quite prevalent, it is best to get yourself screened for active tuberculosis infection if you display any such symptoms.

Tuberculosis (TB) - When A Person Can Develop It?

Most people know all about Asthma, how dangerous it is and most importantly, with the rising levels of pollution and irritants how people are getting affected by it all over the world. Just like famous events, incidents and festivals have their special date in the calendar, May 1 apart from being the International Labour Day, holds another significant stance worldwide. As it is celebrated as the World Asthma Day. This day marks the initiation of the Asthma awareness campaign worldwide.

Understanding Asthma in brief

Asthma is a long-term respiratory condition, in which the airways of the human system may unexpectedly and suddenly narrow, often in response to an allergen, cold air, exercise or emotional stress. Common symptoms include wheezing, shortness of breath, chest tightness, and coughing.

Why is Asthma Day important?

World Asthma Day is celebrated every year on the first Tuesday of May. This year it falls on 1st May. The day is celebrated to spread awareness about Asthma and how people all over the world can spread it amongst their families. Therefore to commemorate the event and educate the students in school and parents at home, World Asthma day was commenced. The aim of this campaign is to make people understand the types of Asthma that can affect them and immediate safety tips so as to ensure that the severity of the disease can be curtailed. 

Things to keep in mind about Asthma

All over the world, there are several people who do not opt for Asthma treatment and that proves to be a fatal mistake later on in life. Chronic Asthma disease can be easily prevented by a simple treatment in the initial stages. People who suffer from Asthma often face chronic attacks if they forget to carry their inhaler and different kinds of allergies are also very fatal for asthma people.

Things that can trigger Asthma in people

Dust 
Pollens
Gastroesophageal Reflux
Pet Dander
Certain foods 
Exposure to chemicals 
Excessive physical activity 
Stress 
39-50% Of Sinusitis patients have Asthma also 
Extremely cold conditions
Signs someone is suffering from Asthma 

Persistent coughing
Difficulty in breathing
Wheezing 
Tightness in chest
Diagnosis and severity are established by a simple air blowing test known as Spirometry.

Chest X-ray and Sinus X-ray Help 
Serum IgE a blood test tells about type and severity
Severe cases may require special blood test known as Arterial Blood Gases to look at blood oxygen and carbon dioxide.

Sheet anchor of therapy is the inhaled medication to dilate airway and to reduce inflammation. The dose being in microgram dose is harmless and delivered to the site of the problem.  New drugs known as Omalizumab and Benralizumab are approved for specific nonresponding patients with severe asthma.

Prevent asthma from being harmful

Asthma is a chronic disease can stay for the rest of someone's life. So on this World Asthma Day make sure that you know how it can be treated and prevent the disease from harming someone you love. Here are some treatment tips.

First get to know more about asthma and become a partner with the doctor to carry out treatment for a long time period.

Be aware of the allergens that may trigger asthma and prevent them from coming in contact with the person.

Make sure to keep the doctor updated regarding the status of a patient's condition and for any sign of potential risk.

If a loved one is suffering then ensure that they lead their life as per the guidelines shared by the doctor, in order to prevent any risky situation. 

So here are the important things that you should be knowing about asthma. And, in case you notice any of the symptoms mentioned above, one should immediately contact their doctor. On this World Asthma Day be aware of the disease and keep the people safe who are suffering from it. Stay Healthy!

World Asthma Day - Spreading Awareness Is Important!

Ways to identify and treat Angina pain

Angina or angina pectoris is the pain, discomfort or tightness in the chest that occurs when the blood flow to the heart muscle cells is not enough to meet its energy needs. It is not a disease itself but rather a symptom of the coronary heart disease.

What are the different types of angina?

1. Stable angina: It is the commonest form of angina. It can be triggered by stress or physical activity and usually only lasts a few minutes.

2. Unstable angina: It happens when you're resting or aren't very active. The pain is strong and long lasting, and may keep recurring. It may be a signal of an impending heart attack.

3. Variant angina: This might take place when you're asleep or at rest. This sudden tightening or narrowing of the heart's arteries causes a lot of pain.

How u know what your are experiencing is an angina pain?

You might be having angina pain if you suffer from one or more of these symptoms:

- Chest pain
- Heartburn
- Breathlessness
- Nausea
- Dizziness
- Restlessness
- Fatigue
- Pain in your arm, neck, jaw and back
- Numbness or loss of feeling in your arms, shoulders or wrists

Immediate Relief from Angina

If previously advised by a certified doctor, patients can take antiplatelet medicines which are blood thinners and prevent unstable angina. Final treatments include angioplasty (repair of a blocked blood vessel through surgery), insertion of a coronary artery stent (a tube that is used to treat weakened arteries) or a heart bypass surgery for serious complications.



Ways to Identify and Treat ANGINA PAIN?

Asthma is an inflammatory disease, which affects the airways of your lungs (respiratory tract that pumps oxygen into the lungs). It is long term in nature. It is characterized by shortness of breath, coughing and wheezing. It occurs a few times a day or a few times a week depending on the person it affects. Sometimes it worsens during the night.

What triggers Asthma?

Airborne particles such as dust mites, mould spores, pollen and cockroach waste.
Infections in the respiratory system such as a common cold.
Cold air can also trigger asthma.
Physical or outdoor activities which make you pant such as running, skipping, jogging and jumping can cause shortness of breath, thus triggering asthma.
Pollutants and irritants in air such as smoke.
Some medications can also trigger asthma.
Stress and nervous attacks (panic attacks) also trigger asthma.
How to manage asthma better by changing your lifestyle:

Try to avoid keeping animals in your houses such as dogs, cats and rabbits. Many times animal fur, waste, urine and saliva contains particles which can cause allergic reactions and make you cough uncontrollably. This, in turn, triggers asthma attacks. If you have pets try keeping them away from your bedroom.
Dust mites also cause allergies which trigger asthma. So wash your carpets, rugs, bed-linen and pillowcases in hot water.
Bugs and insects such as cockroaches are not only unhygienic but can also trigger asthma. Cockroach droppings near your bed, kitchen and food are dangerous and you should call an exterminator to get rid of these bugs.
Sometimes, the heavy fragrance also aggravates your respiratory tract and triggers shortness of breath. Avoid using heavy perfumes, deodorants and room fresheners.
Pollution also triggers asthma. Dust particles come out from the vehicles and mix with the air. If this air is inhaled, it might trigger uncontrollable asthma. So try to cover your mouth with a cloth when you step out of your house.
Asthma can be very severe and can bring many hurdles in your day to day activities. Changing your lifestyle and certain habits can reduce asthma to a great extent.

Lifestyle Changes to Manage Asthma Better

The vast majority of us never consider our sinuses when we take a full breath through the nose. For others, this problem of stuffy nose, excruciating headaches, fever and infections, in episodes of sicknesses, last up to twelve weeks no less than four times each year. We should take a look at how this issue occurs and how to help them through Maharishi Ayurveda. This is how sinusitis occurs:

Sinus issues are really brought on by a fundamental irregularity in Prana Vata (the subdosha of Vata that sees the brain and the head) and Shleshaka Kapha (a subdosha of Kapha, which administers oil and dampness levels).
At the point when these two sub-doshas are at the same time imbalanced, another problem emerges. Ama, the sticky waste that is a result of processing, gets blended with Shleshaka Kapha in the sinus area, shaping a more toxic, sticky bodily fluid called Shleshma. Shleshma settles in the zone and stops the channels of the sinuses. Because of the confinement and blocking, Pitta dosha likewise gets to be imbalanced, and irritation occurs.
At that point when each of the three doshas are out of adjustment, the body turns into a ground for bacteria, allergens, or infections. Air contamination, changes of hot and frosty climate increase it further. Eating unnecessary measures of chilly, sweet, not being able to workout or exercise can add to the problem.
Here is how it can be cured through Ayurveda:
Step 1: Eat foods that are not very hot, furthermore not very chilly. Stay away from extraordinary temperatures or foods that have extreme temperatures, for example, stew peppers or super cold foods and refreshments. Eat properly cooked, warm dinners that are light, sustaining, and simple to process. For instance, for breakfast, you could eat a stewed apple, and for the dinner eat khichari (a light and sustaining porridge made with two sections rice and one section mung dhal).
Step 2: Drink a lot of water seasoned with flavours, to decontaminate the sinuses of toxins and to allow the harmful waste that has developed to stream out. Bubble two quarts of water, empty the water into a bottle, and put two leaves of basil, two thin cuts of ginger, four leaves of mint, two bits of clove, and   teaspoon of marshmallow root. Continue drinking this water for the duration of the day, however, make it again every morning.
Step 3: Detoxify the body and restore the sinus territory. Eat a lot of natural, crisp foods grown from the ground. Abstain from eating eggplant, banana, tomato and pepper, since these block the channels. Try not to skip meals or suppers, since that will annoy the stomach and create more problems for your body.


Sinusitis Treatment - How Ayurveda Can Help With It?

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