Hypothyroidism is a condition in which the thyroid gland is not producing the thyroid hormones adequately. This is a fairly common condition.

What is thyroid gland?

The thyroid gland is a small butterfly-shaped gland located just below Adam s apple. It encircles the windpipe or the trachea. It is about 4 cms in height and weighs about 18 gms. This gland is responsible for the secretion of thyroid hormones. Hormones are chemicals produced by special glands like thyroid, adrenals, ovaries etc. They act as messengers and are carried by the blood to the various target organs.

What are the hormones produced by thyroid gland and what do they do?

The thyroid hormones are of two types   T3 (Tri iodo thyronine) and T4 (Thyroxine). These hormones are mainly responsible for the body s metabolism - a process in which food is converted into energy in the cells. They influence growth and development and regulate various bodily functions which are mentioned below:

Heartbeat
Body temperature
Breathing
Body weight
Metabolism of fat
Menstrual cycles in females
Functioning of Nervous system
Digestion
Burning calories etc.
What is Hypothyroidism?

Inadequate production of hormones by the thyroid gland is termed as hypothyroidism. This is also called Underactive thyroid state. Hypothyroidism can make the body s development to slow down and reduces metabolism rates.

What are the causes of Hypothyroidism?

Hypothyroidism can be caused by a number of factors:

Hashimoto's thyroiditis: This is the commonest cause. This is an autoimmune disorder (normally body s defence system fight against external infections. In autoimmune disorder the defence system attacks the healthy cells of the body by mistake). In Hashimoto s thyroiditis the immune system/defence system produces antibodies that attack the thyroid gland and destroy it.
Iodine deficiency in diet. For the production of thyroid hormones iodine is very important. The body does not produce iodine normally, so it needs to be supplemented from outside. Iodine is mainly present in the food we eat. It is mainly present in shellfish, salt-water fish, eggs, dairy products. If a person does not eat iodine rich foods, he may end up with iodine deficiency leading to hypothyroidism. Currently, this causative factor is on the decline due to government initiative of table salt with iodine.
Surgery: Surgery to remove thyroid gland (for e.g. thyroid cancer treatment, overactive thyroid etc.)
Radiation to the neck (to treat cancer in the neck area): The thyroid gland cells are damaged due to the radiation.
Treatment with radioactive iodine: This treatment is used for managing hyperthyroidism/overactive thyroid, where the thyroid gland produces excessive thyroid hormones. One of the treatment modalities is by radioactive iodine. Sometimes this radiotherapy destroys normal functioning cells which lead to hypothyroidism.
Certain medicines: Certain medicines used to treat heart conditions, cancer, psychiatric conditions etc.   for e.g. amiodarone, lithium, interleukin-2, interferon-alpha.
Pregnancy: Pregnancy (the reason is unclear but it has been noticed that the thyroid may get inflamed after delivery   this is called Postpartum thyroiditis.
Damage to the pituitary gland: Pituitary gland is a gland which is present in the brain. It produces a hormone called TSH (Thyroxine-Stimulating hormone).The TSH tells the thyroid gland how much thyroid hormone it should make. If the levels of thyroid hormone in the blood are low, then the TSH will stimulate the thyroid gland to produce more Thyroid hormone.
Hypothalamus disorders: This is an organ in the brain. This produces a hormone called TRH (Thyrotropin Releasing Hormone) which acts on the Pituitary gland to secrete TSH. So any disorder of Pituitary gland will indirectly effect the production and secretion of Thyroid hormones. These are very rare disorders.
Congenital thyroid defects: Some babies are born with thyroid problems. This is due to the thyroid not being developed normally during pregnancy. Sometimes the thyroid gland does not function normal. This can be identified by screening for thyroid disorders in the first week after delivery. This is usually by a blood test using a small drop of blood from the baby s heel.
What are the different types of hypothyroidism?

One classification is based on whether the defect is with the thyroid gland or not:

Primary hypothyroidism: The problem is in the thyroid gland itself and thus there is reduced production /secretion of thyroid hormones.
Secondary hypothyroidism: Here the problem is with the Pituitary gland or the Hypothalamus. This results in abnormal production of TSH or TRH, which indirectly leads to less production and secretion of thyroid hormones.
Another classification is based on the symptoms and levels of the thyroid hormones and TSH:

Overt hypothyroidism: Here the patient is having the symptoms. Further the T3/T4 are low and TSH is high
Subclinical hypothyroidism: Here patient may or may not have symptoms. The T3/T4 levels are normal but TSH is high. In this situation the patient is at an increased risk of developing overt hypothyroidism in the future especially if he has Thyroid peroxidase antibodies on testing.
Who are at risk of developing Hypothyroidism?

Women have a higher risk of suffering from hypothyroidism than men.
Older people are at increased risk.
People suffering from other autoimmune diseases like Coeliac disease, Type-1 Diabetes Mellitus, Vitiligo, Pernicious anemia, Multiple sclerosis, Rheumatoid arthritis, Addison s disease etc.
People with psychiatric conditions such as bipolar disorder
People with Chromosomal abnormalities like Down syndrome, Turners syndrome also have a high risk of suffering from hypothyroidism.
What are the symptoms of hypothyroidism?

Symptoms vary from person to person. They may also mimic other conditions and hence be difficult to diagnose. Symptoms may also develop very slowly over a span of moths-years. Some of the characteristic symptoms of this disease are:

Depression
Constipation
Hair loss
Dry hair
Dryness of the skin
Tiredness
Body pains
Fluid retention in the body
Irregular menstrual cycle
Increased sensitivity to cold
Reduced heart rate
Increase in size of the thyroid gland   called Goitre. This is due to constant stimulation of the thyroid gland by TSH.
Weight gain
Carpal tunnel syndrome
Hoarse voice
Infertility
Loss of libido/sex drive
Confusion or memory problems especially in the elderly
What are the symptoms to look for in a baby if you suspect hypothyroidism?

Infants suffering from congenital hypothyroidism may show no symptoms or exhibit signs of excessive drowsiness, cold hands, cold feet, constipation, hoarse cry, poor growth or absent growth, poor appetite, bloating of abdomen, puffiness of face, swollen tongue, persistent jaundice.

How to diagnose hypothyroidism?

Blood tests:

TSH: This hormone is made in the pituitary gland and it stimulates the thyroid gland to produce thyroxine. If the thyroxine levels are low in the blood, the pituitary gland produces and secretes more TSH into the blood to act on the thyroid gland to produce more thyroxine. A raised TSH level indicates hypothyroidism. Other tests are not usually necessary unless a rare cause of hypothyroidism.
T4: A low level of thyroxine indicates hypothyroidism.
T3: these levels are generally not needed to diagnose hypothyroidism
Anti-Thyroid peroxidase antibodies (anti-TPO antibodies) or Anti- thyroglobulin antibodies are present in 90-95% of patient with autoimmune thyroiditis.
Other blood tests include Creatinine Kinase, Serum Lipids, Complete blood picture etc.
Ultrasound of the neck is done if the patient presents with a thyroid swelling.
What is the treatment of hypothyroidism?

Overt hypothyroidism is treated by synthetic Thyroxin hormone which should be taken every day on an empty stomach at least 30   45 minutes before breakfast. The treatment is continued for the rest of the patient s life. Regular thyroid function tests are done once every 8 weeks-12 weeks to adjust the dose of the thyroxine in the initial period of diagnosis. Once the thyroxine dose is stabilised, the tests can be done even once a year. This treatment is quite effective.

Sub-clinical hypothyroidism is only treated if the patient is a woman and is contemplating pregnancy, in patients with symptoms or if the TSH is quite high.

What are the side-effects of thyroxine medication?

There are few side effects if any. Most people tolerate these medications quite well. An important consideration before starting medication is to check if the patient has chest pain/angina. These people are started on the least available dose. If these patients are started on a higher dose they notice a worsening of their angina pains.

Side effects mainly occur if the thyroxine dose is high which leads to hyperthyroidism. The symptoms of this could be palpitations 9increased heart beat), weight loss, profuse sweating, anxiety, irritability etc.

There are some tablets which increase with thyroxine tablets. These include carbamazepine, iron supplements, calcium supplements, rifampicin, phenytoin, warfarin etc.

What are the complications of hypothyroidism?

If untreated hypothyroidism can lead to:

heart problems like heart attack due to increased levels of bad cholesterol like LDL, or heart failure due to fluid retention
obesity
infertility
joint pains
depression
A pregnant woman with hypothyroidism is at increased risk of giving birth to a baby with congenital hypothyroidism, also known as cretinism. Further, the woman may have pregnancy related complications like pre-eclampsia, premature delivery, low birth weight baby, anemia, post-partum haemorrhage (bleeding after delivery) etc.
Myxoedema is another complication where the patient has extremely low levels of thyroid hormone. The body temperature drops drastically making the person lose consciousness or go into a coma.
References:

2013 ETA Guideline: Management of Subclinical Hypothyroidism; European Thyroid Association (Nov 2013)
Management of primary hypothyroidism: statement by the British Thyroid Association Executive Committee; British Thyroid Association (2015)
The diagnosis and management of primary hypothyroidism; Royal College of Physicians and others (June 2011)
Suh S, Kim DK; Subclinical Hypothyroidism and Cardiovascular Disease. Endocrinology Metabolism (Seoul). 2015 Aug 4.
UK Guidelines for the Use of Thyroid Function Tests; British Thyroid Association (2006)
Gaitonde DY, Rowley KD, Sweeney LB; Hypothyroidism: an update. American Family Physician. 2012 Aug 1 86(3):244-51.
Bindra A, Braunstein GD; Thyroiditis. American Family Physician. 2006 May 15 73(10):1769-76.
Wilson GR, Curry RW Jr; Subclinical thyroid disease. American Family Physician. 2005 Oct 15 72(8):1517-24.
British National Formulary; NICE Evidence Services (UK access only)
Baumgartner C, Blum MR, Rodondi N; Subclinical hypothyroidism: summary of evidence in 2014. Swiss Medical Weekly. 2014 Dec 23 144:w14058. doi: 10.4414/smw.2014.14058. eCollection 2014.

Know Everything About Hypothyroidism

The gall bladder is a very small organ located behind the liver. This organ stores the bile created by the liver and releases it whenever needed. We rarely pay attention to this organ until there is a problem and most gallbladder related problems are very painful. Unknowingly you may be harming your gall bladder by eating certain types of food like red meats and saturated fats. On the other hand, eating some types of food can improve your gall bladder health. Some such foods are:

Fiber-rich foods: Fruits and vegetables are rich sources of fiber and a must in a balanced diet. Fiber helps keep the gall bladder healthy and also helps prevent gallstones from developing. An easy way to add more fibre to your diet is to incorporate a salad with your lunch and dinner.
Water: Water not only helps hydrate the body but also helps maintain the water levels required in bile. Ideally, a person should drink 8 glasses of water a day. This should not all be drunk at one time but should be spaced out through the day. Drinking too much water at one time will result in the body expelling it in the form of urine instead of absorbing it.
Foods rich in Pectin: Pectin is a dietary fiber that binds cholesterol in the stomach and helps in its removal from the body. Since cholesterol is one of the major causes for gall stones, eating pectin-rich foods helps reduce the risk of gallstones. Some foods that are rich in pectin include citrus fruits, strawberries and apples.
Flaxseeds: Eating just one tablespoon of flax seeds a day can boost your health in a number of ways. One of the many benefits of including flaxseeds in your diet is a healthy gall bladder. Flax seeds contain mucilaginous fiber or fiber that forms a gel. This type of fiber aids in the liver s synthesis of bile acids and thus keeps the gall bladder healthy.
Omega 3 Fatty Acids: Not all fats are bad for the body. Omega three fatty acids play an important role in producing anti-inflammatory compounds. Some rich sources of omega 3 fatty acids include olive oil, avocados and flax seeds.
Citrus fruits: Citrus fruits are very rich in vitamins like vitamin C. a deficiency of this particular vitamin can cause gall stones. For this reason, eat plenty of citrus fruits and other fruits and vegetables such as bell peppers and broccoli that are rich in vitamin C. 

Gallbladder Health - Foods that Can Help maintain it!

The gallbladder is a small organ in the abdomen that stores bile. Bile is necessary to digest fat that people take with food.

Unlike other cancers, Gallbladder cancer is not very common. It is also treatable in the early stages. However, in most cases, Gallbladder Cancer is detected in late stages. At these stages, the chance of a recovery is remote. What makes early diagnosis uncommon is the absence of specific signs or symptoms.

However, there are some signs that people need to look out for.

Signs of Gallbladder Cancer

Though there are not many specific symptoms, following signs can indicate a broad range of abnormalities, including some cancers.

Pain in the upper right quadrant of abdomen

Bloating

Fever

Weight loss

A feeling of nausea

Yellowing of the skin and eyes (sign of jaundice)

Many of these symptoms may involve other organs or indicate completely different ailments. This is why people need to see the symptoms in light of other concomitant symptoms and gauge the seriousness of the problems. If a person feels that a particular symptom is not solely a gastrointestinal problem, rush to the doctor immediately.

Causes of Gallbladder Cancer

Causes of Gallbladder Cancer are not entirely clear. However, in most cases, cancer spreads from the glandular cells of the gallbladder. These cells are found in the inner body of the gallbladder. This is also known as Adenocarcinoma. Slowly, it spreads from the inner body to other organs of the body.

Risk Factors

Though the reasons for Gallbladder Cancer are not yet known, certainly there are some factors that exacerbate the risk:

Gender
More women than men suffer from Gallbladder Cancer.

Age
The risk of Gallbladder Cancer increases with age.

History of Gallbladder Stone
It has been observed that most of the Gallbladder Cancer patients have had a history of gallbladder stones. However, this does not mean that Gallbladder Cancer is common in people with a history of gallbladder stone.

Chronic gallbladder infection, gallbladder polyps, etc. can increase the risk of Gallbladder Cancer.

Stages of Gallbladder Cancer

Gallbladder Cancer is categorized into different stages in accordance with its spread:

Stage I
If cancer is confined within the glandular cells of gallbladder, it is put in this stage.

Stage II
If cancer has grown out of the inner layers and has invaded the outer layer of the organ, it is put in the second stage.

Stage III
If cancer has grown to such an extent as to invade nearby organs like liver, stomach, small intestine, etc., Gallbladder Cancer is put in this stage.

Stage IV
The last stage of Gallbladder Cancer is characterized by large tumors, taking into their fold multiple organs in the vicinity. Tumors may also spread to distant parts of the body.

Treatments of the Gallbladder Cancer

The treatments depend a lot on the stage of cancer and overall health. The primary goal is to remove the diseased gallbladder. It may also be possible to resect part of the liver and bile duct along with the gallbladder.

However, if that is not possible, doctors may need to resort to other therapies to prevent the disease from spreading. This may involve Radiation Therapy or Chemotherapy or a combination of both.

There are many treatments available for Gallbladder Cancer depending upon the severity of the cancer. This is why it is important to consult a doctor before opting for any treatment.

Gallbladder Cancer - Signs, Causes & Treatment Of It!

Eczema is something which can really blight the quality of the life of a person. Sometimes, even the most mundane of things can cause our skin to have a reaction, resulting in allergic eczema. However, while it is annoying and painful, there are ways to go about treating it.

It is quite important, though, to understand what exactly eczema is. Simply put, it is a condition which occurs when the skin of the person suffering from it is inflamed.

Among the various groups of people who suffer from eczema, a lot of them are actually babies. However, they thankfully are able to grow out of the issue by the time they become adults. While it is true that eczema can strike any part of a person s body, among the places it strikes most often are the face, the neck and behind the sweat spots of the body i.e. the area behind the knees and around the ankles.

What causes allergic eczema?
Eczema is a lot of the time, a condition which is genetic. That being said, there are certain things which can go a long way into making it worse, which include stress and dry climates as well as external materials which irritate the skin touching it, like soaps which are just too strong.

What are the Treatment Options?
When it comes to things, which have the potential to make the situation a lot better, there is a group of medicines which are part of the antihistamine group which can work wonders. An interesting thing when it comes to the treatment of allergic eczema is the fact that a lot of the treatment for the issue involves a management of the inflammation that occurs along with an attempt to take better control and manage the immune system of the person who has eczema.

Depending on the severity of eczema a person has, a possible course of treatment involves making use of corticosteroids, which are strictly a prescription based way to go about treating eczema. Keeping this in mind, it is of the highest importance to make sure that whenever the steroids are being taken by mouth, there is a full adherence to what the doctor has recommended or directed.

As a last ditch resort, if the condition is really bad, there is a possibility of going for Ultra Violet Therapy in order to make it better. However, if one is looking for ways to reduce the intensity of their eczema sans higher doses of medication, stress management in something that can work well. In addition to this, a humidifier can do a lot to improve the situation.

Allergic Eczema - Ways You Can Contact It!

Foot problems can occur due to a number of causes that, in most cases, are easily diagnosed. An orthopedic is a specialized doctor whose advice you should seek if you have any kind of discomfort in one or both of your feet. Discomfort may include chronic or regular pain, difficulty in movement and/or disfigurement. These are generally a result of arthritis, physical injury or a genetic or hereditary condition. In some of the cases, the pain and discomfort can be treated without any surgery, by using medications. However, in extreme cases, where medication, physical therapy, and other such non-surgical methods fail to have any impact, surgery is the only way to go.

These surgeries are less invasive and require a limited recovery time. They are also one of the most successful types of surgery. The surgical procedure is successful in dealing with the main complaints of a foot problem. It successfully treats a foot by,

Relieving pain: The pain in your feet interferes with your work, making it difficult to carry on with your daily life, affecting your personal and social relationships. Pain often indicates an underlying problem, and it is easier and effective to treat the problem with a surgery, as it relieves you from the chronic pain.
Restoring function: If your feet do not function properly, it will be impossible for you to move, as they are necessary for mobility. When a simple stride becomes a problem, your whole lifestyle is affected. Accepting defeat is not an option. A good orthopedic can help you to get back to your normal daily life by surgically treating your feet thus ensuring they function properly.
Improving appearances: Foot deformity, due to a number of reasons such as polio or bone spurs, can lead to a restricted lifestyle. Movement is hampered and so is freedom. Surgically it can be treated and the appearance of your feet can be improved.
Arthritis is also a cause of a number of foot problems. In more cases than not, surgery becomes a necessity to treat your foot. Here are some of the surgeries that cater to arthritis-related foot problems:

Repairing Fracture: If the fracture is beyond repair by non-surgical methods, surgery is the last refuge for an orthopedic surgeon. Surgery will include repositioning of the bone and the use of supports to keep them in position.
Arthroscopic debridement: This surgical procedure helps to remove inflamed tissues or spurs from the joint.
Arthrodesis: Also known as joint fusion, it involves the removal of the ends of the bones at the joint and replacing them with metal pins or screws.
Osteotomy: The surgical procedure involves realignment of a joint by cutting the bone.

Foot Problems - Can They Be Treated By Surgery?

Home remedies for skin allergies 

Skin allergies are often indicated by redness, scaly, itchy, chapped or bumpy skin. These may occur due to a variety of factors. Usually, when an allergen or a foreign element comes in contact with skin, it triggers an immune system response leading to an allergic skin condition. Other factors may include climatic changes like heat and cold, infections, cosmetics, specific foods or even medications resulting in skin allergies. Often, mild skin allergies do not sustain for long even if these are not treated. However, to get relief from the pain and added discomfort caused by these skin allergies, these home remedies are a lot easier and safe bet.

Cool down the itch

Use typical ice packs or cold running water over the infected part to treat itching. Using a cold water cloth over infected area relieves from suffering. Do not try using hot water as it relaxes in the beginning but makes the condition worse later.

Scare the scar

Aloe vera is the best bet in almost all skin ailments due to its remarkable anti-bacterial, anti-inflammatory and anti-fungal properties. Regular oral intake of 2-4 teaspoons of aloe vera gel or the application of its pulp on areas of dark spots or scars eradicates scars and rashes from the face and other skin areas.

Act on acne with apple cider

The best option to treat the most irritating yet much prevalent skin ailment is apple cider vinegar. Add one part of apple cider vinegar to three parts of water. Mix it well. Use cotton balls to apply this solution on acne directly and leave it for 10-15 minutes. Then rinse with water. Apply this three times a day to seek optimum results.

Coconut oil sways away eczema

First, wash your hands with utmost care. Then, pat them dry. Use your fingers to slowly rub coconut oil on the affected area. Leave it for some time to get it dry. Use it as many times as you want to get the benefits. Actually, application of this oil on the affected portion is recommended for a longer duration for best results.

Bye-bye to rashes with baking soda

Baking soda is to be applied on the rashes directly. Then, to get better results, press the skin softly and see the rashes disappear soon.

If you would like to consult with me privately, please click on 'Consult'.


Quickie Home Remedies for Skin Allergies

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