Cystic Fibrosis is a genetic disorder that is known to affect some of the vital organs of the body including the lungs, digestive system to name a few. For long it was believed that cystic fibrosis affects a person in their childhood. However, various research and studies suggest that adults are also susceptible to this inheritable disorder. In this article, we will discuss the cause and symptoms associated with cystic fibrosis.

Cause
The epithelial cells that line the stomach, nasal cavity and lungs, are responsible for the production of the digestive fluids, sweat, tears, mucus. The Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) gene codes for a protein called the CFTR protein. The CFTR protein, a membrane protein plays a pivotal role in transporting the chloride ions of the epithelial cells inside and out of the cell. This regulation of the chloride ions goes a long way in ensuring that the mucus produced is free-flowing and thin.

In the case of Cystic Fibrosis, the CFTR gene that codes for the protein undergoes a mutation. With the CFTR protein unable to perform its function, sticky and thick mucus builds up and clogs some of the major systems of the body including the digestive system, reproductive, and respiratory system. There is also a higher salt content in the sweat of the affected person.

For a person to be affected by cystic fibrosis, he/she must inherit a copy of the mutated CFTR gene from both the parents ( Autosomal Recessive Disorder) at birth.

Symptoms
The symptoms associated with cystic fibrosis depends on the organs and systems affected.

The thick mucus formed can clog the digestive tract resulting in incomplete absorption of the essential nutrients from the food. This may have an impact on the overall growth and development of the body.
- There may be stunted growth or no weight gain.
- The stool may appear greasy and foul smelling. Some may also suffer from constipation.
- Newborns and infants may suffer from an intestinal blockage.
Cystic fibrosis, left unattended can lead to diabetes, intestinal blockage or obstruction.
- The mucus can also block the bile duct triggering a host of problems including liver disorders.
- At times, the obstruction or blockage can occur at the junction where the large and the small intestine meets (Distal intestinal obstruction syndrome).
The thick mucus can also affect the lungs and the respiratory system by blocking the tubes that act as a passage carrying the air inside and out of the lungs. As a result,
- A person may suffer from lung infections frequently.
- There may be difficulty in breathing, stuffy and blocked nose, or wheezing.
- Some people may also suffer from a chronic cough with a thick sputum.
Left untreated the complications can worsen resulting in

Nasal polyps, Chronic infections, Hemoptysis (there is blood while coughing), and Pneumothorax (air fills up in the space bifurcates the chest wall from the lungs).

In severe cases, there may be a respiratory failure.

Cystic fibrosis can also trigger fertility problems (both in males and females).

Cystic Fibrosis- Causes and Symptoms!

It is no longer so surprising to read about alarming air pollution levels in our cities. On more than one occasion, these levels have risen above the danger levels. For some people, this may simply create an annoying fog that makes it difficult to see. For others, it can cause serious health issues. Air pollution is one of the most common reasons for the growing instances of asthma and allergies. Children are most susceptible to such diseases caused by air pollution.

Asthma and Allergies
Asthma can affect children even before their fifth birthday and the condition is characterized by breathlessness caused by a constriction of the airways. While the root cause of asthma is unknown, it is usually seen that asthmatic patients are more sensitive to others to particles in the air such as pollutants, dander, dust, smoke etc. Thus, the airways construct as a reaction to these allergens. Changes in the weather, a sudden cold draft or the flu can also aggravate asthma.

Can you Protect Your Children from Asthma?
Wheezing, panting, finding it difficult to breathe and a persistent cough are some of the signs of asthma. If you notice these symptoms, you must consult a doctor immediately. At home, here are a few things you could do.

Avoid exposing your children to smoke: Do not smoke around your children or allow others to smoke around them. If you cannot give up the habit, wear a smoking jacket when you smoke and take this off before you play with your children. When you ll go out, drive with the windows up so that your child does not inhale exhaust smoke. Set your air conditioner to circulate air within the car itself.
Dust often: Try and keep your home as dust free as possible. Use a wet cloth to clean so that the dust does not fly in the air. Wash all your bed linen once a week. Carpets and rugs should be vacuumed regularly or dusted outside. It may also be a good idea to invest in dust mite impermeable covers for your child s mattress and pillows.
Keep your Pets clean: If you share your home with pets, bathe them once a week and brush them daily. Do not let them climb on to the furniture or your beds. Also, avoid having their toys lie on your beds.
Wear a face mask: Try and time your child s outdoor activities when the pollution levels are low. Buy yourself and your child a face mask that will filter the air they breathe in. These should be worn whenever they play outdoors.
These simple steps could help your child be healthier and can prevent asthma and other such allergic reactions.

Increasing Asthma & Allergy In Children - What Should You Do?

Uterine fibroids are referred to as benign, abnormal growths which tend to develop in the uterine walls of a woman. The size of such growths can range from a few centimeters to even excess of a few inches. As such, they can cause the uterus to increase to the size of a five month pregnancy. Although, the symptoms of fibroids are not always apparent, they often cause heavy bleeding and pain in women. A recent research concluded that around 60 to 75 percent women contract such fibroids by the age of 50, at least once in their life.

Depending on the site of formation, uterine fibroids are distinguished into different types. Intramural fibroids in the lining of the uterus and subserosal fibroids which develop outside the uterus are the most commonly observed fibroids.

What causes Uterine Fibroids?
Although, the exact reason for the formation of fibroids are obscure, medical professionals have determined certain factors that may affect their formation. Some of them are:
1) Hormones: Progesterone and estrogen, produced by the ovaries regenerate the uterine lining during each menstrual cycle and trigger the growth of fibroids.
2) Family history: If you have had a family history of uterine fibroids, then you&#x2019;re likely to develop the condition yourself as well.
3) Pregnancy: The production of progesterone and estrogen increases during pregnancy which increases the likelihood of fibroids.

What are the signs of the condition?
Depending on the location and size of the tumors, symptoms of such fibroids include:
1) Heavy bleeding and blood clots during periods
2) Pain in the pelvis
3) Frequent menstrual cramps
4) Pressure and pain in the lower abdomen
5) Swelling in the abdomen
6) Pain while intercourse

What is the procedure of the treatment?
Ultrasound and pelvic MRI are common diagnostic procedures to check for uterine fibroids. After diagnosis, depending on your age, size of the fibroid and your comprehensive health, the doctor would prescribe you with appropriate medications. Only after medications prove futile, doctors opt for minimally invasive surgeries.


Causes and Symptoms of Uterine Fibroids

Chromosomal abnormality happens when a cell has too many or too few chromosomes. The most common form of chromosomal anomaly is Down s syndrome. If a parent has a chromosomal anomaly, she/he will pass it on to the child. PGD or Pre-implantation Genetic Testing aims to select only the embryos with normal chromosomal count and only these embryos are implanted to achieve a healthy pregnancy and bring down the number of children affected with a chromosomal anomaly.

The risk of Aneuploid pregnancy:

The older a woman is when she tries to conceive (aged 35 or more), the higher the risk of Aneuploid pregnancy (carrying a baby with genetic or chromosomal abnormality). Most of these pregnancies end in miscarriages and the few that come to term produce babies with chromosomal abnormalities.

Causes of Chromosomal Abnormality:

Usually, chromosomal abnormalities occur due to an error in the cell division. Meiosis refers to the cell division, which the sperm and the egg undergo during the development procedure. Normally, meiosis breaks the chromosomal material into two equal halves, so that each of the parents contributes 23 chromosomes to the pregnancy. However, when the number of chromosomes in the cell goes up or down than the normal, it results in genetic/chromosomal anomalies.

PGD Procedure for a Chromosomal Anomaly:

If a couple elects to go for Pre-implantation Genetic Diagnosis, they have to undergo ICSI Cycle. ICSI cycle initiates a fertilization cycle to produce embryos. When the embryos reach upto day 5 and blastocyst are formed, they are biopsied and further sent to genetic lab for detecting the chromosomal abnormalities. The embryos are incubated for the entire duration of the genetic screening. Only the embryos that the genetic test clears are implanted. PGD never reveals the gender of the embryo.

PGD can help detect the single genetic disorders that may lead to the following ailments:

  Cystic fibrosis
  Muscular dystrophy
  Tay-Sachs
  Sickle cell anaemia
  Thalassemia
  Turner syndrome

PGD is a revolutionary science that can help root out incurable disorders linked to genetics. It ensures that pregnancy is sustained until term and a healthy baby is born.

Suffering From Genetic & Chromosomal Anomalies - Know About PGD!

Immunity building or having good immunity is the prime need of parents for children of today's generation. Due to hectic lifestyles, inadequate nutrition, exposure to pollution and physical and mental stress children easily fall prey to recurrent infections. It takes a toll on both their physical, mental health and development leading to absence from school for longer durations.

Common health issues faced by children:

Lack of concentration and memory.

Loss of appetite

Irritability

Infections like chronic cough and cold, influenza, digestive problems taking place in a recurrent manner.

Recurrent allergies

Physical and mental stress

Headaches and lack of sleep

Recurrent use of higher doses of medicines makes their immunity further weak and they get caught in the vicious circle of illness and medicine.

Is there any answer to the above problems?  Definitely yes - It is Suvarnaprashan!

What is Suvarnprashan?

Suvarnprashan refers to a unique Ayurvedic remedy, which has been clinically tested and proven to give a boost in immunity and intellect among children. This is usually given to children who are aged between 0-16 years in the form of drops.

Benefits

There are numerous benefits of Suvarnprashan, which help children to lead a healthy and productive life.

It helps to increase immunity

It assists in the promotion of good physical and mental health.

Improves digestion and physical strength.

Intake of Suvarnprashan helps to improve attention span among children, their memory along with the ability to learn.

Irritability, temper tantrums, attention deficits, and psychosomatic problems 

Prevents recurrent infections

Helpful in children who have delayed milestones of growth

Helps to stimulate a child s overall development If given regularly, Suvarnaprashan prevents the occurrence of recurrent diseases in children by boosting their physical & mental immunity which is the need of the hour as we all would agree to the fact that  Prevention is better than cure .

Suvarnprashan - A Boon For Children's Immunity!

Is bedwetting a regular feature in your child? Has this been continuing for a long time and is making you concerned? Nocturnal enuresis is the condition in which a child passes urine when he sleeps at night, unknowingly. It is referred to as bedwetting or nightwetting in Ayurveda. Shayyamutra is the Ayurvedic name of this condition in which shayya refers to sleeping, and mutra means urine.

Ayurvedic guidelines and remedies

You must ensure that your child is getting sufficient sleep. A proper sleep schedule will make it easier for him to wake up when his bladder is full and he needs to urinate.
The bowel must be kept clear to prevent thread worms from troubling at night. They account for being an important cause for bedwetting.
Your child should abstain from food items such as green gram, potato, tea, chocolates, coffee, and spicy foods producing gas.
You must make sure that your child does not drink any liquid right before going to sleep. On the contrary, his bladder should be emptied before going to bed.
Bladder stretching exercises should be undertaken, which are effective for the management of bedwetting in children.
In children who experience bedwetting in spite of being grown up, the reason is usually stress. Stress may occur from various causes and it is important to bring your child s stress under control. For this, he should undertake yoga, mindful meditation, and other relaxation techniques.
There are various Ayurvedic home remedies, which are ideal for managing bedwetting in children. Some of them are as follows:

Fry one spoon of coriander seeds until it turns brown. Mix one teaspoon each of sesame seeds, babul gum, and pomegranate flowers and make a fine powder out of the ingredients. Add crystal sugar to the mixture and give this to your child before bedtime regularly.
Give half a cup of milk and Sarshapa in a powdered state to your child before he/she goes to sleep at night.
Ayurvedic remedies used for curing bedwetting in children aim at strengthening your nervous system and your urinary tract. Vishatinduka vati, Chandraprabha vati, and Shilajitwaadi vati are common Ayurvedic medicines used for treating bedwetting.
Deworming should be carried out for the infestation of intestinal worms, which may provide relief to your child.
Several medicinal herbs are also used for the Ayurvedic treatment of bedwetting. They include bimbi, kataka, amalaki, hareetaki, haridra, khadira, and a lot more.
It is recommended for you to consult an Ayurvedic practitioner before following any Ayurvedic remedy for your child for treating bedwetting. A doctor would prescribe the best remedies after diagnosing your child properly.

Bed Wetting in Children - How Ayurveda Remedies Can Help!

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