Growth hormone or somatropin is responsible for cell growth as well as reproduction. But insufficient somatropin production by the pituitary gland may result in lack in height. It is mostly caused by a serious brain injury, any prevalent medical condition or might occur as a birth defect.

Types
1. Congenital ghd - this form of ghd appears from at the time of birth itself.
2. Acquired ghd- ghd can be acquired during later life as a result of trauma, infection, tumor growth within the brain or radiation therapy.
3. Idiopathic ghd- idiopathic ghd is the third, and comparatively worst kind of ghd since it has no treatment.

Ghd is mostly permanent, but can also be transient. Read on to know how to detect whether you or your child is suffering from growth hormone deficiency (ghd).

Symptoms
Childhood onset
1. Restricted height- compared to other children of your child's age, he/she may be of shorter height, which is a rather conclusive sign to detect somatropin deficiency.
2. Chubby and comparatively younger appearance- your child may have a proportionate body, but if he/she is unnaturally chubby and has a baby-face compared to other children, he/she may be suffering from ghd.
3. Late puberty- your child's puberty maybe later than usual or even not appear at all, depending upon the gravity of the ghd.
4. Hypoglycemia and exaggerated jaundice- low blood sugar is amongst the most primary manifestations of ghd, along with extended duration of jaundice.
5. Micro-penis- micro penis condition is one of the incident signs of ghd, which later escalates to growth deficit as the infant gets older.

Adult onset
1. Fatigue- adults with ghd may experience extreme tiredness throughout the day, with reduced muscle strength.
2. Osteoporosis- osteoporosis, along with bodily deformities, is a common sign in adults with ghd.
3. Lipid abnormalities- a test of your lipid profile may reveal abnormalities in ldl cholesterol, insulin resistance, and impaired cardiac functions.

Tests to determine ghd
1. Physical test- a chart is drawn to determine the proportion of height and weight with respect to your age to detect anomalies.
2. Hand x-ray- a hand x-ray can determine whether the age of bones are at par with your age.
3. Mri-mri scan can determine the health of your brain and pituitary gland.
4. Test for other hormones- growth hormone may not be solely responsible for your health condition, so it is important to determine if other hormone levels are all normal.

Treatment
1. Hormone supplements- hormone supplements like corticosteroids (hydrocortisone or prednisone), levothyroxine (levoxyl, synthroid, etc), and others work to replenish the deficiency of pituitary hormones.
2. Growth hormone injection- gh is injected beneath your skin, to cure gdh. This is a long-term treatment and requires constant monitoring.

All About Growth Hormone Deficiency

Coughing is a common problem of the respiratory tract and often indicates a deeper problem. It can be very irritating and can affect eating habits and socialization. A cough which persists for more than 4 weeks is believed to be chronic in nature. Tuberculosis (TB) is the most common cause of chronic cough in India. TB is an airborne bacterial infection caused by the organism - 'Mycobacterium tuberculosis', that primarily affects the lungs, although other organs and tissues may be involved. Cardinal features are: 

Chronic cough with or without sputum.
Fever more in the night time. 
Poor appetite. 
Unintentional weight loss. 
Read on to know about other common causes of chronic cough and how to manage them.

Allergies: People with allergies usually have a chronic cough, which gets aggravated when exposed to the allergens such as pollen or environmental dust. Staying away from allergen provides relief. Antihistamines are also useful, which most people detected with allergies keep in handy. Inhalers might be required, if there is associated congestion or shortness of breath.
Asthma: This is a very common chronic condition, caused by inflammation and swelling of the lungs, in addition to wheezing and shortness of breath. Asthma patients often suffer from a chronic cough. An asthma attack usually happens during the night or early morning, and is triggered by colds, cigarette smoke, air pollutants or allergens, which can even include certain foods. Most asthmatics usually carry their steroids, inhalers, and bronchodilators, as the onset of attack can be unpredictable.
Bronchitis: This condition of inflammation of the bronchial region is very common among smokers and among the elderly. There is excessive mucus accumulation, which the body tries to clear via coughing. The lungs are weakened and therefore, the coughing is painful.
Gastroesophageal reflux disease (GERD): This is a problem of the digestive system, but regurgitation of food into the airway induces cough. GERD is a chronic issue and so most people also end up with a chronic cough. It is worse with sitting up than with sitting down. Treatment includes H2 blockers to suppress acid production and dietary changes including small, frequent meals and avoiding spicy food items.
Upper airway cough syndrome: There could be multiple problems in the upper airway, which leads to a constant postnasal drip. Here, there is constant dripping of the sputum into the air passage, which can lead to a chronic cough whenever there is impaired air flow. This can be caused by various forms of chronic sinusitis and rhinitis. People diagnosed with this condition usually resort to antihistamines and decongestants for relief.
Other causes: There are a number of other causes as noted below. Smoking, tuberculosis, congestive heart failure, pertussis or whooping cough, foreign body in the airway, cancer in the airway passage, chronic aspiration of foods, etc. can all lead to chronic cough.
The key is to identify the reason that is causing the chronic cough. Most people who are diagnosed are educated to handle it and carry the required medications including steroids, bronchodilators, and inhalers.

Suffering from Chronic Cough - How to Manage it?

Chromosomal abnormality happens when a cell has too many or too few chromosomes. The most common form of chromosomal anomaly is Down s syndrome. If a parent has a chromosomal anomaly, she/he will pass it on to the child. PGD or Pre-implantation Genetic Testing aims to select only the embryos with normal chromosomal count and only these embryos are implanted to achieve a healthy pregnancy and bring down the number of children affected with a chromosomal anomaly.

The risk of Aneuploid pregnancy:

The older a woman is when she tries to conceive (aged 35 or more), the higher the risk of Aneuploid pregnancy (carrying a baby with genetic or chromosomal abnormality). Most of these pregnancies end in miscarriages and the few that come to term produce babies with chromosomal abnormalities.

Causes of Chromosomal Abnormality:

Usually, chromosomal abnormalities occur due to an error in the cell division. Meiosis refers to the cell division, which the sperm and the egg undergo during the development procedure. Normally, meiosis breaks the chromosomal material into two equal halves, so that each of the parents contributes 23 chromosomes to the pregnancy. However, when the number of chromosomes in the cell goes up or down than the normal, it results in genetic/chromosomal anomalies.

PGD Procedure for a Chromosomal Anomaly:

If a couple elects to go for Pre-implantation Genetic Diagnosis, they have to undergo ICSI Cycle. ICSI cycle initiates a fertilization cycle to produce embryos. When the embryos reach upto day 5 and blastocyst are formed, they are biopsied and further sent to genetic lab for detecting the chromosomal abnormalities. The embryos are incubated for the entire duration of the genetic screening. Only the embryos that the genetic test clears are implanted. PGD never reveals the gender of the embryo.

PGD can help detect the single genetic disorders that may lead to the following ailments:

  Cystic fibrosis
  Muscular dystrophy
  Tay-Sachs
  Sickle cell anaemia
  Thalassemia
  Turner syndrome

PGD is a revolutionary science that can help root out incurable disorders linked to genetics. It ensures that pregnancy is sustained until term and a healthy baby is born.

Suffering From Genetic & Chromosomal Anomalies - Know About PGD!

The moment when you learn about your child being autistic can be a life changing moment for you. You might feel all the dreams and aspirations which you built around your child come crashing down on a pile of zilch. However, recent developments in this field show that you can certainly take steps to make your child more comfortable and bond well with them. 

Autism related disorder usually begin before the age of 3, when the child starts encountering problems in communication and social interaction. This article tries to help you find a way to deal with an autistic child:

Learn more about autism: Learn about autism as much as you can; a broad understanding of the causes and symptoms of the disorder can help you understand your child better. This will also enable you to respond to your child s needs better, both physical and psychological. 
Build a strong support system: It is difficult to parent a child who is suffering from autism. Communicating and interacting with your child might be extremely difficult and problematic. In order to overcome this stress, you should have a strong support network, a support network from which you can draw your strength and logic once you have to take major life decisions for your child. 
Review your treatment options: It is advisable to start treatment immediately after the diagnosis is done. Early treatment can help better your child s cognitive skills that can help him/her cope better with the surroundings and circumstances. The treatment options include behavioral training whereby self-help or social skills training is used to work on the child s communication skills and behavior. Specialized therapy is another option whereby the therapies are directed at a particular aspect of the child, primarily speech or physical functioning. 
Focus on your child s diet: Diet plays an important role in the regularization of any disease. Even in case of autism, deficiency of certain vitamins or minerals makes it very important to analyze the diet and then assess it. Consult with the doctor before making any modification to the child s diet. 
Behavioral training: Behavioral training is an aspect of autism treatment that allows the child to adapt to various conditions. Before a child undergoes behavioral training, it is advised to assess his/her behavior, functional abilities and the environment your child belongs to. The objective of this therapy or training is to induce desired behavior and get rid of the undesirable ones.

Tips for Parents to Deal with Autistic Children 

How to Prevent Your Child from Developing Type 2 Diabetes?

Type 2 diabetes (T2DM) is a chronic metabolic disorder that prevents the body from processing sugar or glucose. The disorder causes insufficient production of the hormone Insulin (responsible for regulating sugar into the different parts of your body); or the body's failure to respond to the hormone produced. Although no cure is available for T2DM, there are several ways in which you can help prevent Type 2 diabetes in your child. These are:

1. Get your child to indulge in some physical activity

Spending about 60 minutes of the day on physical activity can help your child to ward off Type 2 diabetes. In terms of screen time, it shouldn't be over 2 hours a day. By doing so, he or she ends up building his or her muscles as well as gets rid of extra fat from the body. An active life would also help your child to maintain an optimal body weight with obesity being a cause of this form of diabetes. Whether it's a sport like swimming, cricket or basketball, or even walking and dancing, physical activity in any form can help in preventing your child from developing Type 2 diabetes.

2. Plan a well-balanced diet for your child

Encouraging your child to have healthy foods and making right food choices can also lower his or her chances of getting this metabolic disorder. Foods high in fiber like whole grain cereals and bread, lentils, fruits, and vegetables should be consumed. Similarly, foods low in trans and saturated fats like lean meat, chicken, yogurt and cheese should be included in your child's diet. Processed foods, as well as sugary drinks, should be no-no when it comes to your child's diet.

3. Adopting proper eating habits

It is not only making the right food choices that are important but eating right as well is vital for preventing the onset of diabetes. Having meals with fix portion sizes is a habit that you need to develop in your child. Ideally, half the plate should be filled with vegetables and fruits; a quarter with lean protein like chicken; and the remaining with whole grain. To accompany the meal, make your child have one cup of no-fat or low-fat milk. Desserts like ice cream and cookies should be allowed only once or twice a week.



How to Prevent Your Child from Developing Type 2 Diabetes?

Attention deficit/hyperactivity disorder (ADHD) is among the most common neurobehavioral disorders presenting for treatment in children and adolescents. ADHD is often chronic with prominent symptoms and impairment spanning into adulthood. ADHD is often associated with co-occurring disorders including disruptive, mood, anxiety, and substance abuse. The diagnosis of ADHD is clinically established by review of symptoms and impairment. The biological underpinning of the disorder is supported by genetic, neuroimaging, neurochemistry and neuropsychological data. Consideration of all aspects of an individual s life needs to be considered in the diagnosis and treatment of ADHD. 

Multimodal treatment includes educational, family, and individual support. Psychotherapy alone and in combination with medication is helpful for ADHD and comorbid problems. Pharmacotherapy including stimulants, noradrenergic agents, alpha agonists, and antidepressants plays a fundamental role in the long-term management of ADHD across the lifespan. 

The management of ADHD includes consideration of two major areas: non-pharmacological (educational remediation, individual and family psychotherapy) and pharmacotherapy. 

I personally support Psychotherapy. Specialized educational planning based on the child s difficulties is necessary in a majority of cases. Since learning disorders co-occur in one-third of ADHD youth, ADHD individuals should be screened and appropriate individualised educational plans developed. Educational adjustments should be considered in individuals with ADHD with difficulties in behavioral or academic performance. Increased structure, predictable routine, learning aids, resource room time, and checked homework are among typical educational considerations in these individuals. Similar modifications in the home environment should be undertaken to optimize the ability to complete homework. For youth, frequent parental communication with the school about the child s progress is essential. 

Symptoms in children and teenagers 

The symptoms of ADHD in children and teenagers are well defined, and they're usually noticeable before the age of six. They occur in more than one situation, such as at home and at school. The main signs of each behavioural problem are detailed below:

Inattentiveness: having a short attention span and being easily distracted making careless mistakes   for example, in schoolwork appearing forgetful or losing things being unable to stick at tasks that are tedious or time-consuming appearing to be unable to listen to or carry out instructions constantly changing activity or task having difficulty organising tasks 
Hyperactivity and impulsiveness: being unable to sit still, especially in calm or quiet surroundings constantly fidgeting being unable to concentrate on tasks excessive physical movement excessive talking being unable to wait their turn acting without thinking interrupting conversations little or no sense of danger 
These symptoms can cause significant problems in a child's life, such as underachievement at school, poor social interaction with other children and adults, and problems with discipline. 

Related conditions in children and teenagers 

Although not always the case, some children may also have signs of other problems or conditions alongside ADHD, such as: 

anxiety disorder   which causes your child to worry and be nervous much of the time; it may also cause physical symptoms, such as a rapid heartbeat, sweating and dizziness 
oppositional defiant disorder (ODD)   this is defined by negative and disruptive behaviour, particularly towards authority figures, such as parents and teachers 
conduct disorder   this often involves a tendency towards highly antisocial behaviour, such as stealing, fighting, vandalism and harming people or animals 
depression 
sleep problems   finding it difficult to get to sleep at night, and having irregular sleeping patterns 
autistic spectrum disorder (ASD)   this affects social interaction, communication, interests and behaviour 
epilepsy   a condition that affects the brain and causes repeated fits or seizures 
Tourette s syndrome   a condition of the nervous system, characterised by a combination of involuntary noises and movements called tics 
learning difficulties   such as dyslexia Symptoms in adults In adults, the symptoms of ADHD are more difficult to define. This is largely due to a lack of research into adults with ADHD. 
ADHD is a developmental disorder; it's believed that it can't develop in adults without it first appearing during childhood. But it's known that symptoms of ADHD often persist from childhood into a person's teenage years, and then adulthood. Any additional problems or conditions experienced by children with ADHD, such as depression or dyslexia, may also continue into adulthood. By the age of 25, an estimated 15% of people diagnosed with ADHD as children still have a full range of symptoms, and 65% still have some symptoms that affect their daily lives. The symptoms in children and teenagers, which are listed above, is sometimes also applied to adults with possible ADHD. But some specialists say that the way in which inattentiveness, hyperactivity and impulsiveness affect adults can be very different from the way they affect children. For example, hyperactivity tends to decrease in adults, while inattentiveness tends to get worse as the pressure of adult life increases. Adult symptoms of ADHD also tend to be far more subtle than childhood symptoms. 

Some specialists have suggested the following list of symptoms associated with ADHD in adults: 

carelessness and lack of attention to detail 
continually starting new tasks before finishing old ones 
poor organisational skills 
inability to focus or prioritise 
continually losing or misplacing things 
forgetfulness 
restlessness and edginess 
difficulty keeping quiet and speaking out of turn 
blurting out responses and often interrupting others 
mood swings, irritability and a quick temper 
inability to deal with stress 
extreme impatience 
taking risks in activities, often with little or no regard for personal safety or the safety of others   for example, driving dangerously 
Additional problems in adults with ADHD As with ADHD in children and teenagers, ADHD in adults can occur alongside several related problems or conditions. One of the most common conditions is depression. Other conditions that adults may have alongside ADHD include: 

personality disorders   conditions in which an individual differs significantly from an average person, in terms of how they think, perceive, feel or relate to others 
bipolar disorder   a condition that affects your moods, which can swing from one extreme to another 
obsessive-compulsive disorder (OCD)   a condition that causes obsessive thoughts and compulsive behaviour 
The behavioural problems associated with ADHD can also cause problems such as difficulties with relationships, social interaction, drugs and crime. Some adults with ADHD find it hard to find and stay in a job. If you notice any of the above in your child or yourself , it is worth making the effort and spending some time and money to have your child and or yourself assessed on a priority basis as ADHD causes neural changes in the brain. 

Attention Deficit Hyperactivity Disorder (ADHD) - A Guide!

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