Though breast cancer has become very common, the good news is that more women than ever are living a healthy life to tell their survival stories. They have not just survived, but are thriving. Let us take you through a couple of survivor stories which not just gives strength and hope, but also the immense courage to stand up and fight it. The names are, however, changed to prevent identity.

Help yourself and others too: For most women, getting diagnosed with blood cancer can mean the end of life. While for the medical person, it is just another individual, for the individual, there is an entire world to think of, her world. What will happen to her family, her job, her life in total. Each person is different, and so the approach has to be different. It should not be a routine combo of surgery, chemo, and radiation. While some hospitals do it, giving a personalized touch helps. That is what happened Susan, who had a complete set of people including dietitian and psychiatrist to help her. The change that she saw with this approach led her to give a helping hand to others. She presently helps people fight and overcome breast cancer and has an extremely fulfilling life.

Shrink the tumor, not your life: For a person with two kids, Tina was aghast when she was diagnosed with breast cancer. She was just 31, and her second daughter was just turning 1, she was extremely distraught. But, her family stood with her through those testing times when she would not have time to run with her daughter or walk along with her mother. With immense support from her family, she is now free of cancer and is a Zumba instructor and now spends quality time with her daughter.

An experiment that worked: At 46 years of age, Maya was diagnosed with stage 3 breast cancer. She found a lump in her breast, which turned out to be breast cancer. The doctor said she would need it removed, and she also opted for surgery. What worked for her, though, is the fact that she was advised to try tamoxifen, which was not so strongly recommended during the initial times. She went ahead and tried, and even after 30 years down the line, is still free of cancer.

Two lives saved: At 23, Sonia was diagnosed not just with stage 4 breast cancer, but also with pregnancy. Re-testing yielded negative results. So she went ahead with chemo and radiation, but the abdominal fullness continued, and when tested again, the tests confirmed her pregnancy. She carried it through, and delivered 4 weeks prematurely but is very healthy and cancer-free now.

Breast Cancer Survivor Stories - Get Inspired!

As life expectancy is increasing so is the incidence of vertebral body (VB) fractures now being the commonest fracture of the body. PVP is an established interventional technique in which bone cement is injected under local anaesthesia via a needle into a fractured VB with imaging guidance providing instant pain relief, increased bone strength, stability, decreasing analgesic medicines, increased mobility with improved quality of life and early return to work in days.

In this era of minimally access surgery replacing open surgeries, PVP is a novel procedure & should be in the first line of management in place of conservatism or major spine surgery for painful uncomplicated compression fracture spine.

Morbidity & consequences of spinal fracture:

Traumatic VB is a painful condition requiring bed rest restricting daily activities markedly
Left untreated it can cause DVT, increase osteoporosis, loss of VB height, respiratory & GI disturbances, emotional & social problems secondary to unremitting pain, loss of independence with high cost of rehabilitation.
High risk of primary or consequential damage to neural, bony or disc element
Increased wedging, deformity & increase incidence of adjacent VB
Chronic pain of altered spine mechanics
Uncomfortable braces & sleep disturbance because of pain & discomfort with its sequels.
Cost of surgery and hospital treatment
Cost of implants
Phobia of surgery
Prolonged recovery period & Extensive rehabilitation
Changed spinal mechanics & transition syndrome
Major surgery & anesthesia with its own complications
Results / Outcome

PVP is a novel procedure with high benefit to risk ratio, which is highly underutilized in relation to the high prevalence of the vertebral.
Different studies show an immediate pain relief in (85   90)% of patients with low complication rate ranging from (1-5)% depending upon the type of lesion.
PVP does augment height of VB but ideal would be kyphoplasty
Patient is either off medicine or on reduced doses.
Patient feels so well that he almost forgets if he had VB

Percutaneous Vertebroplasty (PVP) is an emerging interventional technique in which surgical polymethyl methacrylate bone cement is injected under local anaesthesia via a large bore needle into a vertebral body (VB) under imaging guidance providing increased bone strength, stability, pain relief, decreased analgesics, increased mobility with improved QOL and early return to work. Started in 1984 by Galibert PVP is done in host of indications.

Senile osteoporotic compression remains the commonest Indication. Other indications are Metastatic VB, Multiple myeloma VB, VB haemangioma, Vertebral osteonecrosis & for strengthening VB before major spinal surgery. The benefit has been extended to the traumatic stable uncomplicated VB compression (VCF) which is commoner in younger age group with active life profile and prime of their career where strict bed rest and acute or chronic pain are unacceptable and they are more demanding for proactive treatment approach so as to be back to work ASAP.

Discovering the fact that VB is the commonest of body, its incidence >the hip, it becomes imperative to take it more seriously. With increasing life-span there is more of aged osteoporotic population, more so due to sedentary indoor lifestyle and post menopausal osteoporosis. Diabetics, smokers & alcoholics are at higher risk of developing osteoporosis. I have seen such alcoholic patient developing six spine fractures in just three months time from a single fracture being on complete bed rest.

Quick fix of fracture spine makes patient walk back same day instead of bed rest of months together avoiding morbidity & mortality of prolonged bed rest, making bedridden patient walk, in a way bringing patient back to normal life.

In this era of MAS replacing open surgeries, PVP is a novel procedure & should be in the first line of management in place of conservatism or major spine surgery for painful uncomplicated compression.

Morbidity & consequenses of spinal 

Traumatic VB is a painful condition requiring bed rest restricting daily activities markedly.
Left untreated it can cause DVT, increase osteoporosis, loss of VB height, respiratory &
GI disturbances, emotional & social problems secondary to unremitting pain, loss of independence with high cost of rehabilitation.
High risk of primary or consequential damage to neural, bony or disc elements.
Increased wedging, deformity & increase incidence of adjacent VB
Chronic pain of altered spine mechanics.
Uncomfortable braces & sleep disturbance because of pain & discomfort with its sequels.
Morbidity and complication of spinal surgery 

Cost of surgery and hospital treatment
Cost of implants
Phobia of surgery
Prolonged recovery period & Extensive rehabilitation
Changed spinal mechanics & transition syndrome
Major surgery & anesthesia with its own complications
Preparation & Procedure:
X-ray spine in a/p & lat view. CT is more informative of bone & morphology. MRI is good for soft tissue injuries. Ask for pedicle size in all dimensions and construct a 3D image aiming needle placement and cement filling in scan room itself as rehearsal of PVP. This reduces operative time & gives better results. Conventionally PVP is done by hammering the vertebroplasty needle through the bone. Here we use light weight drill to bore through the vertebra. It is important to set the needle at exact entry site & side with right trajectory aiming the defects.

In lateral view needle should go through middle of the pedicle going up to anterior 1/3 of VB. In P/A view the needle can be in midline or paramedian depending upon & if uni/bipedicular approach is planned. Approach varies as per location of vertebra, anterolateral in cervical, costotransverse/parapedicular in thoracic & transpedicular in lumbar vertebra.

Do bone biopsy if there is any doubt about lession. Do dye test (vertebral venography). Make cement more radiopaque by adding barium /or tungsten. Inject cement with 1or2 ml luerlock syringes strictly under fluoroscope in lateral view & cross checking in P/A view. Stop injecting either there is adequate filling or at the first sight of ectopic cement leak. Keep sample cement to see for hardening. Remove needle with rotational movement before cement hardens.

Pain relief is by virtue of different mechanisms postulated :

Cementing of fragments.
Thermal neurolysis of VB nerve ending due to heat of polymerization.
Washing away of nociceptor chemicals.
Neurolytic action of liquid monomer.
By allowing early ambulation decreasing pains of immobility & bed rest.
Complications 

PVP is generally safe with low risk.
Ectopic cement leak is frequent but generally inconsequential.
Outcome 

PVP is a novel procedure with high benefit to risk ratio, which is highly underutilized in relation to the high prevalence of the vertebral
Different studies show an immediate pain relief in (85   90)% of patients with low complication rate ranging from (1-5)% depending upon the type of lesion.
PVP does augment height of VB but ideal would be kyphoplasty.
Patient is either off medicine or on reduced doses.
Patient feels so well that he almost forgets if he had VB

Vertebroplasty (PVP) / Kyphoplasty - Approach To Management Of Vertebral Body Fractures!

In case you have a diseased uterus, which makes you infertile, you can undergo a procedure known as uterus transplant or uterine transplant to get pregnant. In the process of sexual reproduction, a diseased uterus does not allow embryonic implantation. This factor is referred to as uterine factor infertility or UFI. As a result, you will not be able to get pregnant.

Who requires a uterus transplant?
This procedure involves women who have UFI and women who had their uterus removed by hysterectomy. Women who have a damaged uterus on account of an injury or infection, which does not function anymore, can also undergo a uterus transplant procedure. Women from the age of 21 to 45 are eligible for this procedure. Many women are born without having a uterus. This condition is called Mayer-Rokitansky-K ster-Hauser syndrome.

Procedure
Uterus transplantation begins with undertaking a uterus retrieval surgery on the uterus donor. The uterus, which is recovered has to be stored and transported to the location of the patient undergoing the transplant. An ischemic tolerance may last over 24 hours. Three major surgeries have to be carried out with the recipient. Firstly, a transplantation surgery is required in which the donor s uterus gets transplanted. In case pregnancy develops, a caesarean section surgery has to be performed. The patient is given immune suppressive therapy. After childbirth, a hysterectomy is done in order to terminate the immune suppressive therapy.

Will the women be able to get pregnant after having sex?
Women receiving a uterus transplant will not be capable of becoming pregnant without undergoing fertility treatments. The transplanted uterus is not connected with the fallopian tubes, which is the location of the normal fertilisation process. The women will require to carry out IVF or in vitro fertilisation to become pregnant after a uterus transplant. IVF is a process in which the eggs are removed from the ovaries and get fertilised in a laboratory. Then, they are implanted in the uterus. After undergoing the uterus transplant procedure, a woman has to wait for a period of one year. The uterus requires time for healing and after recovery, the embryo may be implanted for pregnancy. After giving birth successfully, a woman will be able to keep the transplanted uterus.

She has the option to get pregnant again. However, after giving birth twice, a hysterectomy must be carried out for the removal of the uterus. This is done so that the woman can stop using the immune suppressant drugs, which are associated with major risks. Uterus transplant is a relatively new technology. In October 2014, the first healthy baby was born to a woman who had undergone a uterus transplant. This surgery is kind of experimental in nature and is usually the last option for getting pregnant. 

Diseased Uterus - Can it be Replaced?

A fracture requires quick and careful medical attention to ensure proper healing and alignment of the bone. Most fractures usually recover within six weeks but that is only half the problem. A lot of other tissues get damaged in the process when there is enough stress placed in the body to fracture a bone. Additionally, when you are unable to move that bone, you will have joint stiffness and significant muscle weakness.

After a fracture, physiotherapy might be recommended to guarantee that you come back to your ideal capacity. You might have to go for regular appointments to your physiotherapist in order to achieve full recovery. Usually, your physiotherapist will try to prevent your post-fracture stiffness in the nearby joints and muscles after the initial six weeks while you are recovering from your fracture. After six weeks or later, if x-rays show that the bone has not been fully healed, your physiotherapist can take a shot at recovering full movement of the joints and muscles near the affected area. 

Here are five ways in which physiotherapy helps heal post-fracture:

Physiotherapy after a fracture can help you enhance your muscle movement. In case you have fractured your leg, your physiotherapist can help you improve your walk and help you decide whether you need to take the support of a walking stick, crutches or a cane. In case you have broken an arm or shoulder, exercises focused on reaching and grasping are included.
Modalities might be used to help with the pain and swelling. Your physiotherapist may choose to use ice, heat or whirlpool baths.
Electrical stimulation can also be used to improve your muscle movement. You need to keep in mind that while inactive treatments like electrical stimulation or ultrasound might be used, you also need to keep your muscles physically active to better your movement and strengthen your bones.
If you have had surgery to join the fractured bone, you may have surgical scar tissue. Scar massage can decrease scar attachments and increase movement around the scar.
Exercise to improve the scope of movement and strength can also be started. Particular focus points need to be treated in the joints around the fractured area. If you have fractured a bone close to your elbow, exercises need to be included for your elbow, wrist, and shoulder. Moreover, a fracture in the shin needs to include exercises for the knee, lower leg, and hip. Exercise can guarantee that your bone can endure the load during daily routine work. Make sure to consult with your physiotherapist to learn the correct exercises for your condition.
A fracture can be very painful and might lead to a disability or problem in movement. Depending on the seriousness of the damage, the loss may be temporary or permanent. Physiotherapy can help you come back to your optimum function as quickly as possible.

Physiotherapy - 5 Ways It Can Help Post Fracture!

Kidney cancer refers to any form of cancer that involves the kidney. The disease usually originates in two portions of the kidney   the renal pelvis and the renal tubule. It is one of the most common types of cancer, affecting nearly one out of every 63 people.

Obesity, older age, high blood pressure, smoking and others are some of the factors that increase the likelihood of developing kidney cancer. A person diagnosed with kidney cancer in the early stage will most likely encounter symptoms like   

  Blood in the urine 

  A lump near the kidneys 

  A persistent pain near the kidneys 

  Fever and night sweats 

  Fatigue and tiredness 

  Weight loss 

One should follow up with an oncologist upon experiencing the above symptoms. Is kidney cancer curable? Kidney cancer treatment depends on multiple factors   the stage and type of cancer, the patient s overall health condition etc. However, if cancer has metastasized, the doctor/specialist may recommend palliative treatment to manage the symptoms and improve your quality of life. 

Often, people think of palliative treatment as an end-stage treatment. Nevertheless, the approach can prove beneficial if given during the initial stages. It is about living for as long as possible in the most satisfying way possible. 

A team of healthcare professionals come together to meet your emotional, physical, and social needs. Treatment may include   

  Radiation therapy to ease pain from the disease that has spread to the bones

  Arterial embolization   a method that blocks the supply of blood to the kidneys and the tumour present inside 

  Immunotherapy   helps the immune system to fight against cancer cells 

  Targeted therapy   works by targeting cancer-specific proteins, genes and tissues that contribute to the growth of cancer 

Palliative treatment, as a part of integrated oncology, has been a boon to cancer patients worldwide. It not only helps deal with the disease physically but also helps to cope mentally. 

Kidney Cancer Cure - What Should You Know?

Collectively grouped under the Ewing sarcoma family of tumors, Ewing's sarcoma is the second most common primary bone cancer occurring predominantly in children and in adolescents. Very rarely is it experienced in adults above the age of 30.

Typically forming in the bones of the chest, pelvis, head, back or trunk and in the long bones of the arms and legs, Ewing's sarcoma is believed to originate in certain kinds of primitive cells. When it begins to affect similar kind of cells found outside the bone, it is usually called an extraosseous Ewing's sarcoma.

Causes
1. Similar to all types of Ewing tumors, Ewing's sarcoma is generally caused by an alteration in a certain cell compelling a gene named EWS found on chromosome no. 22 to move over to a DNA section on any one of the surrounding chromosomes resulting in the activation of the EWS gene.
2. While it is not a hereditary condition, it usually occurs after childbirth, but no substantial evidence has been found as to why it happens so.

Symptoms
Symptoms of Ewing's sarcoma may include:
1. Swelling and pain especially in the arms, legs, back, chest or pelvis
2. Swelling accompanied by joint immobility
3. A bone breaks having no apparent cause
4. Swelling which may or may not be accompanied by a warm, tingling sensation
5. Fever resulting from unknown causes
6. Lumps or bumps which do not subside over time
7. Abnormal weight loss
8. High levels of fatigue
9. Tumors which have spread over to the lungs may cause shortness of breath
10.Tumors spread over to the spine may cause weakness or even paralysis.

Because the symptoms of Ewing's sarcoma can hardly be distinguished from symptoms caused by other infections or injuries, an early diagnosis is absolutely necessary for a successive treatment.

Causes and Symptoms of Ewing's Sarcoma

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