Cystic Fibrosis is a genetic disorder that is known to affect some of the vital organs of the body including the lungs, digestive system to name a few. For long it was believed that cystic fibrosis affects a person in their childhood. However, various research and studies suggest that adults are also susceptible to this inheritable disorder. In this article, we will discuss the cause and symptoms associated with cystic fibrosis.

Cause
The epithelial cells that line the stomach, nasal cavity and lungs, are responsible for the production of the digestive fluids, sweat, tears, mucus. The Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) gene codes for a protein called the CFTR protein. The CFTR protein, a membrane protein plays a pivotal role in transporting the chloride ions of the epithelial cells inside and out of the cell. This regulation of the chloride ions goes a long way in ensuring that the mucus produced is free-flowing and thin.

In the case of Cystic Fibrosis, the CFTR gene that codes for the protein undergoes a mutation. With the CFTR protein unable to perform its function, sticky and thick mucus builds up and clogs some of the major systems of the body including the digestive system, reproductive, and respiratory system. There is also a higher salt content in the sweat of the affected person.

For a person to be affected by cystic fibrosis, he/she must inherit a copy of the mutated CFTR gene from both the parents ( Autosomal Recessive Disorder) at birth.

Symptoms
The symptoms associated with cystic fibrosis depends on the organs and systems affected.

The thick mucus formed can clog the digestive tract resulting in incomplete absorption of the essential nutrients from the food. This may have an impact on the overall growth and development of the body.
- There may be stunted growth or no weight gain.
- The stool may appear greasy and foul smelling. Some may also suffer from constipation.
- Newborns and infants may suffer from an intestinal blockage.
Cystic fibrosis, left unattended can lead to diabetes, intestinal blockage or obstruction.
- The mucus can also block the bile duct triggering a host of problems including liver disorders.
- At times, the obstruction or blockage can occur at the junction where the large and the small intestine meets (Distal intestinal obstruction syndrome).
The thick mucus can also affect the lungs and the respiratory system by blocking the tubes that act as a passage carrying the air inside and out of the lungs. As a result,
- A person may suffer from lung infections frequently.
- There may be difficulty in breathing, stuffy and blocked nose, or wheezing.
- Some people may also suffer from a chronic cough with a thick sputum.
Left untreated the complications can worsen resulting in

Nasal polyps, Chronic infections, Hemoptysis (there is blood while coughing), and Pneumothorax (air fills up in the space bifurcates the chest wall from the lungs).

In severe cases, there may be a respiratory failure.

Cystic fibrosis can also trigger fertility problems (both in males and females).

Cystic Fibrosis- Causes and Symptoms!

It is a known and proven fact that eating while consuming alcohol is necessary. One tends to grow hungrier, the more he or she drinks alcohol. This is because alcohol has the attribute to stimulate one s appetite in such a way that one would have you craving for food that is rich in salt and high in fibre. Consuming only alcohol ignoring the hunger would lead to several diseases like pancreatitis and issues with the liver.

Though the appetite of an individual during alcohol consumption tends to incline towards snacks like pizza, french fries, nuts and cheese cubes, it is wise to opt for healthier food choices. Salty food can worsen the dehydration effects of the body. And as the body tends to be dehydrated during drinking, it is better to avoid salty food. High-fibre food items are not good for the health either. It delays the digestion process, which is not a good sign for the body. Also, it is also not advisable to eat food in large portions before going to bed, especially after alcohol intake.

There is a variety of healthy food that one can eat along with alcohol

Soup: A clear soup, like chicken clear soup or vegetable clear soup, which has a broth-like texture, is a healthy choice. Creamy soup with cream of chicken or cream of mushroom should be avoided as it would make one heavy, thus delaying the digestion process.
Rice: Plain rice is said to be one of the best food that is easy to digest, paired up with a light vegetable dish. It is very nutritious as well.
Chicken sandwich: Grilled chicken sandwich without cheese and mayo is a healthy food tip as it contains sodium.
Popcorn: Popcorn does not contain fat, neither is it high-fibre. It is the best low-calorie food to go along with alcohol and it tastes really good too.
Wheat crackers: Wheat crackers contain whole grains. It is full of complex carbohydrates, which help the alcohol to absorb easily. It also consists of Vitamin B, which like potassium, gets reduced with the consumption of alcohol.
Banana: It is rich in potassium. Though an individual would never have a banana along with alcohol, it is healthy as the level of potassium should be taken care of while drinking alcohol.
Wheat bread: Wheat bread toast can be consumed with alcohol without butter or cheese. It is an alternative to wheat crackers for those who do not prefer it.
Oats: Cooked food is easy to digest with alcohol, so a pot of cooked oatmeal can be a healthy accompaniment. It can be spiced up a bit to add flavour.
Salad: Salad is refreshing and healthy at the same time. It can be bland, but it is better to have healthy salad as an accompaniment than having salty food with alcohol.
Milk cereal: Cereal, especially whole grain cooked with low-fat milk, is healthy.
By being aware of the right eatables, the ill effects of alcohol can be mitigated to a large extent.

Alcohol - 10 Healthy Foods that You Can Eat With It!

The sugar found in milk and other dairy products such as yoghurt and cheese is called lactose. An enzyme in the small intestine called 'lactase' breaks lactose into galactose and glucose. When the lactose is not digested properly by the small intestine, it passes unbroken into the colon. The bacteria in the colon break the lactose down into hydrogen and carbon dioxide. People who fail to digest lactose in their small intestines are diagnosed with lactose intolerance.

Usually lactose intolerance only affects adults, but sometimes children do suffer from it. For children, their symptoms can be mild or very severe (for example, cramps, diarrhoea, etc.)
Normally, parents can confuse milk allergy with lactose intolerance. They do share the same symptoms, but they are completely different medical conditions. Milk allergy is caused by the immune system while lactose intolerance is a problem with the digestive system.

The causes of lactose intolerance include:
1. Absence or deficiency of the lactase enzyme
2. Infections in the gastrointestinal tract that damage the lining inside the small intestine
3. Gluten intolerance (It affects lactase production)
4. Genetics (Lactose intolerance can run in the family)

When the lactose is broken down in the colon, certain gases are produced. These gases can cause symptoms such as:
1. Abdominal inflammation and pain
2. Excessive burping
3. Loud sounds in the bowel
4. Excessive diarrhoea and gas
5. Explosive and watery bowel movements
6. A feeling of urgency when it comes to bowel movements (In children, they might feel like they need to get to the bathroom as soon as possible or they might embarrass themselves)

How best to treat it?
Living with lactose intolerance usually involves dietary modifications and taking supplements such as over-the-counter lactase to aid in digestion. For instance, you can replace milk with soy milk, or take lactase before ingesting any dairy product. Or alternatively, you can consume lactose-reduced or lactose-free milk and dairy products.
Calcium deficiency is a serious side effect of lactose intolerance. So incorporate calcium-rich foods such as broccoli, kale, tofu, almond, dried fruits, soybeans, turnip greens, collard greens and fortified orange juice in your diet.

How to Treat Lactose Intolerance in Children

Automatic Implantable Cardioverter Defibrillator is an electronic device that is located in the chest of the patient suffering from arrhythmia. Arrhythmia is a condition which causes abnormal rhythm of heartbeat in the patients. It is a life-threatening condition. The device is located in the chest to correct the rhythm of a heartbeat.

AICD device works in two ways:

Firstly, it tries to correct the abnormal heartbeat rhythm and release high- speed heartbeat pace. This is called cardioversion. Patients with AICD generally do not feel the process.

However, if the effect of cardioversion is null then the device will give a mild electric shock to the patient's heart to correct arrhythmia and reset the rhythm.

This second method is called defibrillation. The patient can feel the defibrillation.

The modern-day AICD device is programmed to store the data about the patient s heart rhythm. Doctors use the programmed device which contains your condition and provides medically correct therapy.

Preparation for AICD Implantation

The patient is required to fast six hours before undergoing the surgery. On admission, prescribed medicine is given to the patient and the latest heart condition is measured by an ECG test. If the patient is on blood-thinning medication, then it will be stopped 24 hours before the surgery.

The procedure will be carried out by a cardiologist. The patient will remain under observation in the hospital for at least two days.

Procedure

The entire process of setting up the device in the chest of the patient takes about 2 hours. The patient is sedated, and the area below the collarbone is numbed for the operation. A small incision is made in the chest area. With the help of imaging techniques, cardiologist sets up the device in the chest. The device is then connected to the veins and the heart. After the surgery, the patient is kept under observation. Heart rate, blood pressure, and overall health condition are observed by the doctors to determine successful implantation of Automatic Implantable Cardioverter Defibrillator (AICD). Post Procedure After the successful recovery of the patient, doctors usually discharge the patient with AICD attached. The doctors give complete care instructions of the device along with health. Doctors also guide the patient through the list of activities that one can and cannot perform. AICD is a life-saving device. Hence, proper care and regular check-ups are recommended by the doctors. The regular check-up of the device is also essential since the device runs on a battery. The doctors also train the patient about the workings of the device. They will also explain about the mild shocks of the device one may receive to correct the arrhythmia. Before leaving, make sure the site of the surgery is dry and healing, and you do not have a fever for the past 24 hours.

AICD Implantation - Know Procedure Of It!

Is your child getting exhausted after a bout of cough? Does he or she suffer from constant wheezing and tightness of the chest? Does your child feel drained out after climbing a flight of stairs? Do you know a child who always seems to run out of breath and cannot participate in school sports tournaments or play outside for a long time? The child could be suffering from asthma, which is a serious breathing problem. Most children are affected by asthma. Staying in a polluted city just makes the condition worse.

Asthma - Know the disease

Asthma is a condition that causes inflammation of the airways, known as trachea and bronchioles.
The muscles around the airways constrict and prevent the smooth flow of air.
The lining of the bronchioles swell and block the airways.
Asthma is mostly triggered by an allergic reaction.
There is a difficulty in breathing out. Exhalation of air is often accompanied by a wheezing, that is, a whistling sound.
There is a constant shortness of breath, feeling out of breath and gasping for air.
There is an uncomfortable tightness in the chest, the feeling of not breathing in enough air.
Coughing bouts in the middle of the night, that leave the child feeling exhausted and completely out of breath.
Causes of Asthma 

Asthma is mostly triggered by asthma allergens. These allergens are mostly pollens and animal fur.

Exposure to pollution, such as dust and smoke
Heredity
Obesity
History of heartburn, GERD and acid reflux
Inflammation of sinus and airways
History of bronchial disorders and pneumonia
Viral infections
Chronic rhinitis
Low immunity causing constant cold and blockage of nose
Treatments of asthma

A nebulizer that turns asthma medicine into a mist can then be inhaled easily
An inhaler can be used to take in inhaled steroids into the lungs or a bronchodilutor
Try and avoid asthma triggers and allergens as much as possible
Avoid physical stress and heat
Get sufficient rest of about 7-8 hours every day

Troubled Breathing - Can It Be a Sign of Asthma?

Tuberculosis is a respiratory disease that is very infectious and usually affects the lungs. It is one of the deadliest diseases that have killed millions of people worldwide. According to WHO, 9 million people get infected with tuberculosis in a year. It is one of the top reasons for death among women aged between 15 to 44 years. Symptoms can range from cough, fever, weight loss and night sweats. Moreover, it is an airborne disease meaning that people having tuberculosis can infect many others around them through coughing, sneezing or sharing a glass or cup.

The main cause of tuberculosis is a bacterium called Mycobacterium tuberculosis. However, there are two types of tuberculosis-

Latent TB- In this condition, the bacteria causing TB is present in the body and is inactive. It is not contagious or results in any symptoms.
Active TB- The bacteria causing TB is active and the person carrying it can infect others as well.
Diagnosis
The most common diagnostic test for tuberculosis is a skin test where an injection of PPD tuberculin which is an extract of the TB bacterium is injected into the skin. After 2 to 3 days, the doctor checks the injected site and if there is red swelling, it means that person has TB. Along with this the doctor also uses a stethoscope to gauge the condition of lungs. However, the skin test is not very accurate to know whether a person has TB or not.

Therefore, doctors also use blood tests, x-rays and sputum tests to find out whether a person has TB or not.

Treatments
Tuberculosis can be cured with medications. However, the correct medicines will depend on the type of TB you have and the period of treatment. If you have latent TB, then taking a single TB drug may be enough. But if you have active TB then you need to have proper medicines prescribed by a doctor for at least 6 months. Some common medicines used to treat TB (active) are:

Isoniazid
Rifampin (Rifadin, Rimactane)
Ethambutol (Myambutol)
Pyrazinamide
Also, antibiotics and injections are used to treat drug-resistant TB that may take longer to cure.
When taking medications or any sort of drugs for TB, one needs to be careful and look out for any side effects that can occur due to TB medications. As medicines taken for TB can cause:

Dark Urine
Loss of Appetite
Nausea or Vomiting
Jaundice
For people suffering from Tb, it is important to follow the full course of medications and not to skip taking any drugs that have been prescribed your doctor. There is a program called Directly Observed Therapy (DOT), where the heath care helper administers and look after a TB patient to ensure that the correct course and medicines are given to the patient.

Treatments For Tuberculosis - What All Should You Know

Don't wait any longer, manage your Pediatric Pulmonologist online with a Lybrate doctor today

Consult for Pediatric Pulmonologist - Online and Easy!

FilterClear All

COMMON SPECIALITIES

COMMON ISSUES