Type 1 diabetes occurs when your pancreas is unable to produce enough insulin to keep the blood sugar ;levels under control. The condition, if not managed properly, can lead to related health disorders and complications, both long-term and short-term.

Health problems arising from type 1 diabetes

Type 1 diabetes can have severe effects on your eyes, kidney, nervous system, and heart health. The most common ailments associated with type 1 diabetes may include the following-

1. Diabetic retinopathy

Diabetic retinopathy is a disease of the eyes, which occurs when the blood vessels in the retina (tissue present at the back of your eyes) are damaged. The walls of the retina gradually weaken from increasing blood pressure and blood sugar levels, and this leads to leakage of blood or fluid into the nearby tissues.

Early symptoms of diabetic retinopathy include-


	
	Blurred vision
	
	
	Floaters
	
	
	Difficulty perceiving colors
	


2. ;Diabetic neuropathy

Diabetic neuropathy unfolds when the nerves are damaged due to type 1 diabetes. The condition mostly affects your feet and legs. Reduced blood circulation due to high blood glucose impedes normal wound healing in the extremities, hence, even a minor bruise ;can develop into a permanent injury.

Symptoms of diabetic neuropathy are-


	
	Numbness
	
	
	Reduced sensation
	
	
	Severe, debilitating pain in the extremities
	


3. Diabetic nephropathy

Also known as ;diabetic kidney disease, the condition is a slow deterioration of the kidney and its ability to function properly. In severe cases, where the levels of blood glucose are extremely high due to type 1 diabetes, diabetic nephropathy can ultimately result in kidney failure ;or end-stage renal disease (esrd).

The following are the symptoms of diabetic nephropathy-


	
	Dark urine
	
	
	Swollen ankles, feet, eyes, or hands
	
	
	Shortness of breath
	


4. Cardiovascular diseases

Cardiovascular diseases refer to a range of heart conditions including blood clots and diseased blood vessels. High blood glucose levels resulting from type 1 diabetes can contribute to the deposition of fat in the walls of the blood vessel. Over time, this may restrict the flow of blood and put you at risk of cardiovascular disorders such as coronary artery disease, stroke, or even ;heart attack.

Symptoms of cardiovascular diseases widely vary, ranging from palpitations ;to chest pain. Sometimes, such a condition may not exhibit any symptoms at all.

Type 1 diabetes complications are related to poor management of blood glucose. The best way to monitor the condition and control the symptoms is to get in touch with your doctor. A specialist in this field can prescribe the correct treatment and help prevent the onset the related health disorders.

Complications Associated With Type 1 Diabetes

When abnormal cells grow inside the brain and are in the form of a mass the condition is called a brain tumour. There are various types of brain tumours that exist. Some of the brain tumours which exist are malignant or cancerous while other may be non-cancerous. A brain tumour can begin in any part of the brain and spread to other parts of the body or vice-versa. The growth rate of brain tumours is different for each individual suffering from it. As per studies, every 2 in 1, 00, 000 people are said to be affected by a brain tumour in india. However, it may come as a relief to some as not all brain tumours are cancerous or life-threatening. Some are benign tumours and seldom pose any threat to the affected individual.

 

Types of brain tumor

Brain tumours may be primary or secondary.

Primary brain tumour

In this type of brain tumour, the abnormal mass of cells that originated in the brain does not metastasize to the other organs. Based on their location in the brain, the primary brain tumours may be of the following types.


	
	Gliomas: one of the most common types of primary brain tumours, gliomas can have their origin in the spinal cord or the brain. Some of the common types of gliomas include astrocytomas (originates in the cerebrum of the brain), glioblastomas (these tumours form from the astrocytes which form the supportive tissues of the brain), ependymoma (these develop from the ependymal cells which are present within the cns), oligodendrogliomas (these tumours are found to arise from the oligodendrocytes).
	
	
	Schwannomas: also called acoustic neuromas, these primary brain tumours form on the nerves that play an important role in regulating the balance and hearing from the inner ear to the brain.
	
	
	Meningiomas: these types of tumours are usually benign and have their origin in the meninges (membranes surrounding the spinal cord and the brain).
	
	
	Primitive neuroectodermal tumours (pnets): primitive neuroectodermal tumours (pnets) are rare malignant tumours that originate from the fetal (embryonic) cells in the brain.
	
	
	Pituitary adenomas: as the name suggests, these tumours arise from the pituitary gland located at the base of the brain.
	
	
	Medulloblastomas: common among children, these malignant primary tumours develop in the brain (lower back) and gradually spread via the spinal fluid.
	


Other types of primary brain tumours include craniopharyngiomas and germ cell tumours.

Secondary brain tumours ;

Unlike the primary brain tumours, these tumours have their origin in the other body parts and organs (mostly in the lungs, skin, colon, breast, and kidney) and then gradually metastasize to the brain. Secondary brain tumours are found to be more common.

 

What Are The Different Types Of Brain Tumours?

What are the different types of sickle cell disease?

Sickle cell disease or sickle cell disorder is a term often used to talk about a group of diseases affecting hemoglobin. It is the oxygen-carrying element of blood that makes up 2 alpha globins and 2 beta globins. Sickle cell disease happens due to beta-globin mutation and depending on the abnormality in mutation.

Types-
Sickle cell diseases can be of many types depending on the gene mutation in the blood. Some of the common types are-

Sickle hemoglobin s disease (ss)
Hemoglobin ss disease or sickle cell anemia is the most popular type of scd. It takes place when hemoglobin s gene mutation is inherited from both mother and father. In simple words, it happens when the child inherits one substitution beta-globin gene from each parent. In this type, the body only produces hemoglobin s. It is mostly found in people of african and indian origin.

Sickle hemoglobin- c disease (sc):
Patients with sickle hemoglobin sc disease have a moderately dissimilar swapping in their genes of beta-globin. Here, both hemoglobin c and hemoglobin s are inherited from each parent. It may cause similar symptoms like anemia but remains relatively l. People of west african and mediterranean origin are more prone to this.

Hbs beta-thalassemia
People with this type of scd inherit one sickle cell gene s and one gene for beta-thalassemia from each parent. Zero and plus are the two common types of beta-thalassemia. While beta 0 thalassemia usually takes a severe form, beta + thalassemia is a milder form of the disease.

Sickle beta-zero thalassemia
Beta-zero thalassemia takes form when the child inherits the beta s gene from one parent and beta 0 thalassemia gene mutation from the other. With similar symptoms to anemia, it is a slightly severe form of beta-thalassemia.

Sickle beta-plus thalassemia
Substitutions in both beta-globin genes take place in patients with sickle beta thalassemia (sb) disease. This may even lead to the requirement of blood transfusion if no normal beta globin is produced. Mediterranean and caribbean people are more likely to have this disorder.

Hemoglobin sd, hemoglobin se, and hemoglobin so
These are the few rare and not less common types of sickle cell diseases. They are also less severe. People with these forms of scd inherit one sickle cell gene s and one gene from uncommon hemoglobin (d, e, or o) from each parent.

Sickle cell trait
Hbas
People with sct have one sickle cell gene s and one normal gene a from both mother and father. Ones with this disorder show few to no signs of the disease and usually spend a normal life. However, the risk to their future generations still exists.
 

What Are The Different Types Of Sickle Cell Disease?

People suffering from sickle cell disease (scd) usually start showing symptoms very early. They can appear to show up even during the first year of life. Symptoms of a sickle cell vary from one person to another and can be mild to serious depending on the condition.

 

Sickle cell disease is a health condition that worsens with time. Despite the absence of any full-proof solution, some treatments prevent further complications. These treatments can help patients receive aid for a lifetime. Simply said, sickle cell diseases can be managed medically.

 ;

Treatment

Treatment in a sickle cell patient depends on the severity of the symptoms. Preventing complications and relieving pain is the primary aim of the diagnosis. They can range from medications to blood transfusions.

 

Concerns

Some of the concerns that need to be taken care of during the treatment of scd are-

 ;


	
	Prevent painful scenarios
	


A painful episode or sickle cell crisis can be avoided by consuming sufficient fluids, wearing warm clothing, and staying away from sudden temperature changes.

 


	
	Avoid infections
	


Children with sickle cell anemia are made safe from infections by using penicillin. Adults with anemia might need to take penicillin all their lives. Doctors should ensure that all vaccinations in children and adults are periodically done to avoid any infections. However, during the covid-19 pandemic sickle cell patients should take extra care.

 ;

Medications

While there can be numerous ways to manage sickle cell treatment, medications help in a significant way. Some of the prescribed medicines are-


	
	Hydroxyurea- it reduces the frequency of sickle crises. Pregnant women should stay away from this according to experts.
	
	
	Crizanlizumab- this drug injected into the patient can help reduce the sickle crises in adults and children over the age of 16.
	
	
	Voxelotor- it is an oral drug used in children over 12. It lowers the risk of anemia by improving blood flow.
	
	
	Pain-relievers- narcotics to prevent excessive pain can also be used during the treatment.
	


 

Surgical procedures


	
	Blood transfusion
	


It is used to prevent stroke and other related complications in patients. This can increase the number of red blood cells in the body that can help reduce the symptoms.

 ;


	
	Stem cell transplant
	


It is also called a bone marrow transplant and is used to replace affected bone marrow with a healthy one. This procedure is carried out between matched donor and recipient. Although it is a known cure for sickle cell disease, various risks involved make it a less used practice.

 

Can Sickle Cell Be Cured?

All types of viral hepatitis diseases are contagious and they can be transmitted from one person to another easily. Although, the modes of transmission may vary.

 

Experts recommend some preventive steps for every type of infection to lower your risk of acquiring or spreading hepatitis infection.

 ;

Here are some preventive measures that may help in preventing the infection:

 

Vaccines

Vaccines for hepatitis a and hepatitis b are the best ways to prevent these viruses. Vaccines are not for all types of hepatitis infections. However, hepatitis a vaccination can help prevent the infection caused by the hepatitis a virus. The hepatitis a vaccine is generally administered in 2 doses. Similarly, there are vaccines available for hepatitis b as well. It is administered within 6 months duration. The same vaccine is helpful to prevent hepatitis d as well. There are no vaccines for hepatitis c and hepatitis e currently.

 ;

Reducing exposure

Hepatitis diseases can be transmitted through bodily fluids, water, and food containing the infection. One can lower the risk of contamination by minimizing contact with these agents. Practicing proper and good hygiene is a way to avoid getting hepatitis through these mediums.

 

You can decrease your risk of coming in touch with fluids containing these viruses by avoiding:

 ;


	
	Sharing used needles and razors
	
	
	Using someone else s toothbrush
	
	
	Touching spilled blood
	
	
	Not using condoms and dental dams during sexual contact
	


 

Handwashing

One must trust in personal hygiene to lower the risk of spreading or acquiring the hepatitis virus. Here are some preventive steps you can follow by washing hands:

 ;


	
	Washing your hands thoroughly after accessing the restroom
	
	
	When you get in touch with an infected person's blood, or stool
	
	
	After daycare routine for caretakers
	
	
	After a diaper change, and before serving food.
	


 

Avoiding contaminated consumption:

Contaminated or infected food and water may become the primary causes of hepatitis infection. One should take these precautions to avoid any contaminated consumption of food or water:

 ;


	
	Avoid eating raw shellfish
	
	
	Beware of fruits that have been washed in contaminated water
	
	
	Avoiding unhygienic street vendors
	
	
	Use bottled water for brushing or oral cleaning in areas where clean water is not available
	
	
	Bringing the water to a 1-minute boil is a must in doubtful areas
	
	
	Heated food to be eaten right away
	


Hepatitis: Some Ways To Prevent Yourself

Congestive heart failure is a condition when your heart stops pumping blood effectively. By being aware of the risk factors, you can manage your condition in a better way. Also, you must consult your doctor on a regular basis to get yourself checked.

Complications Associated With Congestive Heart Failure

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