Cystic Fibrosis is a genetic disorder that is known to affect some of the vital organs of the body including the lungs, digestive system to name a few. For long it was believed that cystic fibrosis affects a person in their childhood. However, various research and studies suggest that adults are also susceptible to this inheritable disorder. In this article, we will discuss the cause and symptoms associated with cystic fibrosis.

Cause
The epithelial cells that line the stomach, nasal cavity and lungs, are responsible for the production of the digestive fluids, sweat, tears, mucus. The Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) gene codes for a protein called the CFTR protein. The CFTR protein, a membrane protein plays a pivotal role in transporting the chloride ions of the epithelial cells inside and out of the cell. This regulation of the chloride ions goes a long way in ensuring that the mucus produced is free-flowing and thin.

In the case of Cystic Fibrosis, the CFTR gene that codes for the protein undergoes a mutation. With the CFTR protein unable to perform its function, sticky and thick mucus builds up and clogs some of the major systems of the body including the digestive system, reproductive, and respiratory system. There is also a higher salt content in the sweat of the affected person.

For a person to be affected by cystic fibrosis, he/she must inherit a copy of the mutated CFTR gene from both the parents ( Autosomal Recessive Disorder) at birth.

Symptoms
The symptoms associated with cystic fibrosis depends on the organs and systems affected.

The thick mucus formed can clog the digestive tract resulting in incomplete absorption of the essential nutrients from the food. This may have an impact on the overall growth and development of the body.
- There may be stunted growth or no weight gain.
- The stool may appear greasy and foul smelling. Some may also suffer from constipation.
- Newborns and infants may suffer from an intestinal blockage.
Cystic fibrosis, left unattended can lead to diabetes, intestinal blockage or obstruction.
- The mucus can also block the bile duct triggering a host of problems including liver disorders.
- At times, the obstruction or blockage can occur at the junction where the large and the small intestine meets (Distal intestinal obstruction syndrome).
The thick mucus can also affect the lungs and the respiratory system by blocking the tubes that act as a passage carrying the air inside and out of the lungs. As a result,
- A person may suffer from lung infections frequently.
- There may be difficulty in breathing, stuffy and blocked nose, or wheezing.
- Some people may also suffer from a chronic cough with a thick sputum.
Left untreated the complications can worsen resulting in

Nasal polyps, Chronic infections, Hemoptysis (there is blood while coughing), and Pneumothorax (air fills up in the space bifurcates the chest wall from the lungs).

In severe cases, there may be a respiratory failure.

Cystic fibrosis can also trigger fertility problems (both in males and females).

Cystic Fibrosis- Causes and Symptoms!

Diabetes is something which has become so common over the past few decades and this is said to be a cause of worry as most people don't understand how to prevent and manage it. This has led to some myths, gaining more than their fair share of popularity. So, wouldn t it be a good idea to get to know a little more so as to separate the myths from the facts?

Weight & watch: One of the most common myths when it comes to diabetes is the belief that a person is going to have his or her life adversely affected if he or she is overweight. While it is true that being overweight happens to be one of the risk factors related to diabetes, it is important to keep in mind the fact that there are other risk factors which are responsible, as well. Some of these factors are age and family history, as well as the ethnicity of the person. Taking this into account, it should not come as too much of a surprise to know that there are quite a few people who are not overweight, but are still fighting diabetes.
Packaged tricks: Considering the rise in the number of people who are suffering from diabetes, this has led to food being marketed specifically for their consumption. However, in reality, whatever represents a healthy diet is sufficient for a person who is diabetic. So a diet which does not have a high amount of saturated fats and trans fats and does not go overboard with starch and sugar, but features a fair amount of lean protein works well too. All the fancy diabetic food, which a person buys, is only likely to drive a great hole in the wallet and not have any additional health benefits. Therefore, the extra spending is nowhere close to being worthwhile and should be avoided.
Fruits punch: Many people are of the opinion that it is the processed and sugary food items, which cause diabetes and this is true to a significant extent. However, some people are of the view that since fruit is natural, diabetics can eat as much of it as they like. This is where the thinking gets dangerous. Some fruits are rich in carbohydrates and so it should be consumed in a reasonable quantity, as part of the daily meal plan. After all, too much of any good thing is bad!

Diabetes - 3 Myths Decoded!

Abdomen pain or abdominal pain is usually experienced in the area between the chest and the stomach. This kind of pain usually comes as a dull cramp that also produces shooting stabs of pains intermittently, or it may be a localised pain in one side of the stomach. This may also be accompanied by inflammation and other diseases related to organs like intestines, kidneys, pancreas, liver, spleen and stomach. So what are the causes of stomach or abdomen pain? Read on to find out:

Food Poisoning: Food poisoning can be caused due to dirty water or contaminated food. This can give rise to various infections as well as conditions like traveler's diarrhea or loose motions.

Gastro-Intestinal Conditions: GERD or gastroesophageal reflux disease and gastroenteritis, among various others, can also lead to abdomen pain as a symptom along with severe acidity and nausea. Irritable bowel syndrome is another major ailment which can leave you with persistent abdominal pain. 

Generalized Pain: This kind of pain occurs in the overall area all around the stomach and may point at the presence of conditions like Crohn's Disease, a traumatic injury, appendicitis, flu, or even a urinary tract infection. Further, when the gas settles and tightens the stomach due to the inability to pass a motion on a normal, regular basis, this may be termed as constipation. This also leads to abdomen pain. 

Localised Lower Abdomen Pain: Pain that is found specifically in the lower area of the abdomen can be caused due to appendicitis, obstruction or blockage in the intestine or colon, and other ailments. This pain can also be accompanied by nausea and vomiting. 

Localised Upper Abdomen Pain: This kind of pain may emanate due to the presence of gallstones, liver inflammation or hepatitis, pneumonia, or even in the middle of a heart attack.

Localised Centre Abdomen Pain: Pain in the centre part of the stomach or abdomen may be caused due to gastroenteritis, an injury or even the accumulation of waste products in the body, otherwise known as uremia.

Abdomen Pain and Women: For women, such localised pain may be caused due to pelvic inflammatory disease, urinary tract infection, endometriosis, ectopic pregnancy, menstrual cramps which are also called dysmenorrhoea, and fibroids. Miscarriages can also cause pain in this part of the abdomen, for women.

Renal Stones: Renal stones or stone in kidney is one of the most common causes of abdomen pain. The pain caused by kidney stone is such that it can make a patient roll in bed and this pain may radiate to toward the groin as well. Persistent pain and nausea that come with vomiting and finally give rise to blood in the vomit or stool should be checked by the doctor immediately, so as to rule out any serious ailment. Imaging tests, ultrasound and an X-Ray can help in diagnosis.

Abdomen Pain - Knowing The Common Causes Of It!

What is ADHD?

ADHD refers to attention-deficit hyperactivity disorder, which is a brain-related condition found among preschoolers, children, teenagers and in many cases extends well into adulthood. These individuals have significant impairment in academics as well as social situations and interpersonal relations. The child has difficulty sustaining attention, phases of hyper activeness and cannot control his/her impulses which make their day to day life at school and home difficult.

ADHD Symptoms

The symptoms of this disorder among children can be categorized under three headings.

1.Hyperactivity which includes

- Fidgets often
- Restlessness
- Inability to stay at one place runs around and tries to climb things
- Trouble playing quietly
- Excessive talking

2. Inattention, which can be divided into symptoms like

- Getting easily distracted
- Tendency to loose things
- Daydreaming
- Facing problems related to organizing things
- Not listening carefully
- Forgetting about daily activities, carelessness

3. Impulsiveness

- Interrupts others as they speak and talks out of turn
- Answers questions without listening to what has been asked
- Not being able to wait for their turn to come

Prevalence :

10-12% of school children before puberty are affected by one or more types of ADHD. ADHD especially hyperactivity is more prevalent in boys than in girls, with the ratio up to 9:1. Inattention and poor concentration are more commonly seen amongst girls. The rate of ADHD in parents and sibling of children with ADHD is 5-10 times higher than in the general population.

ADHD Causes

The probable causes of ADHD among children are,

1. Neurodevelopmental changes - Poorly developed activity of the brain particularly in the areas that control attention and concentration cause ADHD. This causes an imbalance in the neurotransmitters or the chemicals important for brain functioning and development.

2. Genetic Factors - genetic studies show that ADHD is largely hereditary in nature with a heritability of 75% approximately.



What are the Causes and Symptoms of ADHD?

Depression in children is not a very uncommon phenomenon. But if the feeling of sadness persists over a period of time with little or no change to their behavior, then it can be seen as a symptom of depression. Children who are suffering from depression need immediate and utmost care as negligence may cause severe long term effects on the child. Read on to find more about them.

Symptoms
Symptoms that indicate childhood depression vary. Some of the different symptoms which indicate depression are:
1. Social withdrawal
2. Irritability
3. Feeling of worthlessness
4. Difficulty in concentrating
5. Reduced ability to function during events
6. Continuous feelings of sadness
7. Physical complaints

Causes
1. Depression in children can be caused due to the combination of a multitude of reasons.
2. Children from a family history of depression are more likely to be suffering from depression.
3. Similarly if the parents suffer from depression then it is more than likely that the child will also suffer from depression.
4. Children from conflicted families or children and teens who are prone to substance or alcohol abuse can suffer from depression.
5. Reasons such as physical health, environment, genetic vulnerability or biochemical disturbance can lead to depression.

Treatment
The treatment process of depression in children is similar to that of adults and can be treated with psychotherapy and medication. If your child is depressed consult a general physician who after his or her diagnosis may refer you to a psychiatrist. The medical specialist will recommend psychotherapy.

In some instances, a child suffering from depression maybe be suicidal. Parents are advised to be vigilant and observe certain behavioral changes that the child may have adapted to or suddenly switched to.
Some of the signs are mentioned below:
1. Changes in eating, sleeping or activities
2. Isolating oneself even from family
3. Talking of suicide, feeling helpless or hopeless
4. Increased risk taking behavior
5. Substance abuse
6. Giving away possessions

Sessions at first and then opt for antidepressant medication if no significant progress is seen. The best results often result from a combination of prescribed medication along with multiple sessions of psychotherapy.

All About Depression in Children

Everybody desires to possess a beautiful smile but poor lifestyle and dietary habits tend to damage the natural white hue of your teeth and add a yellowish tinge to it. Yellowish and dull teeth are among the major factors that cause embarrassment and affect the quality of your beautiful smile.

The following are some foods that tend to damage your teeth:

1. Potato chips- potato chips are high in starch content and have the tendency to get stuck in your teeth. Floss thoroughly after eating potato chips to ensure effective removal of the food particles that get stuck in your teeth to lessen the risk of plaque build-up in it.

2. Sticky food- food which is sticky in nature often has the tendency to stick on to your teeth for longer than most other foods. Most dried fruits also fall under the category of sticky foods that can damage your teeth to a great extent. Rinse and floss on a regular basis after eating these foods to ensure protection of your teeth against damage.

3. Wine- according to studies, wine has positive effect on your health when consumed moderately; however, it is also responsible for damaging your oral health. If you intake a glass of wine at night on a regular basis, it increases the risk of damaging your tooth enamel and leads to its discoloration. Wine can also affect the calcium content of your teeth, cause bad breath and may result in the imbalance of your mouth's ph level. It is advisable to drink small sips of wine without swishing it for a long time.

4. Coffee and black tea- black tea and caffeinated coffee tend to dry your mouth. Frequent consumption of tea and coffee tend to stain your teeth and it is responsible for the discoloration of your teeth. Make it a point to drink plenty of water to minimize the risk of teeth staining.

5. Carbonated drinks- most carbonated drinks, including diet soda and soft drinks are acidic in composition and therefore, harmful for the health of your teeth. Caffeinated beverages tend to dry out the mouth, therefore, ensure to drink adequate water to balance out the negative impact of the caffeine.

6. Sports drinks- most energy drinks and sports drinks are high in sugar content and thus, have the tendency to damage your oral hygiene; ultimately affecting the appearance of your teeth. Replace your sports drinks with fresh natural juice to lessen the risk of teeth damage.

Foods That Are Ruining Your Perfect Smile

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