Parkinson's disease is a neurodegenerative condition that affects your brain cells which produce dopamine and thus hampering all kinds of motor functioning and other emotional responses. After the disease is diagnosed, medication and therapy can help to provide relief from the symptoms to a large extent but a permanent cure is not possible.

Causes:

The disorder does not have a definite set of causes. A small percentage of the cases have been related to hereditary factors and others have a range of environmental causes associated with them.

1. Genetic factors:

Specific gene mutations and gene variations have been proved to cause Parkinson's, such as SNCA, PARK2, PARK7, PINK1 and LRRK2. These make or recycle proteins which are linked to the disease.

Research shows that men are at a 1.75 times greater risk of developing the condition than women are. Also, age plays a role with most cases occurring after the age of 60.

2. Environmental factors:

Regular exposure to inorganic insecticides, pesticides, herbicides and heavy metals or other toxins may cause the disorder. In rare cases, Parkinson's disease occurs in the aftermath of a severe head injury or immune disorders.

Symptoms:

The symptoms can be classified into two broad categories-

1. Motor symptoms:

The hand tremors when in resting position
The grip loosens
Walking slows down
Facial muscles freeze partially
Speech is slurred
Balance is disturbed
Swallowing is painful
Urination is abnormally frequent
Dementia-like symptoms are seen
There is involuntary twitching of the fingers and toes
Repetition of the same movement in quick succession is nearly impossible
2. Non-motor symptoms:

Dental problems
Vision impairment
Skin disorders
Panic attacks
Excessive secretion of saliva
Extreme weight loss or gain
Sexual problems
Loss of sense of smell
Lowering of the pitch of the voice
Fatigue

Causes and Symptoms of Parkinson's Disease

If you are young chances are you aren t worried about this particular neurodegenerative disease, and rightly so since the only people afflicted by it are above the age of 50. Although, there are a lot of cases where it develops in the younger age bracket, so you need to be careful and examine the signs of early onset Parkinson s and be wary if any of these symptoms apply to you.

Parkinson s is a neurological disorder wherein the dopamine-producing neurons are affected in a particular area of the brain. It can cause tremors and balance problems, eventually worsening over time. Here are some signs that you should keep an eye out for:

Tremors: If you are experiencing tremors, while at rest, in your hands, arms, fingers or your jaw then it is a sign that you need to be aware about. In an excitable or stressful situation, the tremors may even worsen.
Micrographia: Your hand movements become restricted and, as a result, your handwriting may become cramped and the words smaller in size. Examine your handwriting from the past with your present one, if you find a noticeable difference in the size and positioning of the letters and if you feel like the sentences are extremely crowded together, be wary.
Olfactory issues: One of the symptoms of early onset could be the loss of the sense of smell. If you feel like you can t sense stronger aromas like that of spices and pickle or even bananas as well as others and it isn t because your nose is blocked then you need to be on the lookout.
Sleeping troubles: There are times when you feel restless in bed while trying to sleep. If this becomes a routine then it could be a sign that you are prone to Parkinson s. Sudden movements and jerking while sleeping is a bad sign.
Stiffness: If your arms and joints feel stiff without reason, and you feel like free body movement is restricted or limited if you feel like you can t swing your arms or move your fingers freely, it is a definite sign that you might have Parkinson s. Stiffness can even lead to muscle pain in various parts of the body. Bradykinesia or slowness of movement is common with the stiffness of the body.
Constipation: If every time you have to defecate you have to strain yourself and put a lot of pressure on your bowels, and bowel movement does not come naturally or easily, even with the inclusion of roughage in your diet, it is a symptom.

6 Signs Of Early On-Set Parkinson's That You Need To Look Out For

Parkinson s disease is a disorder involving the nervous system. It can start with a mere tremor of one hand and advances to slow movement and stiffness. The face might show little no symptoms in the beginning but the speech might become slurred. With every passing day, the condition worsens. This condition has no permanent cure but the symptoms can be improved with proper medication.

What are the symptoms?
Some unmistakable symptoms include the following:

A sudden shaking of the limb. A sudden tremor of the hand is a very common symptom of this disease.
Stiffness of the muscles that can limit the range of motion and sharp pain.
The posture of the body might get compromised. Often balancing problems are witnessed among many patients.
There could be problems with speech leading to soft, slurry or quick speech. The speech in some cases can become monotonous devoid of inflexions.
Parkinson s disease can lead to slow movement and makes performing of simple tasks difficult.
Patients often find writing very difficult
What are the possible causes of Parkinson s disease?

Specific genetic mutation can lead to Parkinson s disease in folks who have a family history of Parkinson s disease. Certain variations of the gene increase the risk of this disease
Exposure to certain environmental factors or certain toxins can trigger Parkinson s disease in an individual.
Certain cells in the brain known as Lewy bodies can trigger Parkinson s disease.
A certain kind of protein cells within the brain known as alpha-synuclein can trigger the Parkinson s disease in an individual
What are the risk factors?

Heredity: Having an immediate family member or close relative suffering from Parkinson s disease can increase the risk of getting this disease in an individual
Age: Although not a prime risk factor, but an individual over the age of over 60 have an increased risk of getting this disease
Toxins: Exposure to pesticide or certain herbicide increase the risk of Parkinson s
Sex: Men are more likely to get Parkinson s disease than women
What is the medication for Parkinson s disease?

Carbidopa-levodopa: This is a natural chemical that gets passed to the brain and is converted to dopamine by the body. The benefits of this medication might reduce with increased symptoms.
Carbidopa-levodopa infusion: A popular drug in this category is known as the Duopa. It is administered directly into the small intestine in the form of gel through a feeding tube.
MAO-B inhibitors: Drugs from this group include rasagiline and selegiline. This is powerful medicine. Many patient experiences hallucination during the initial days of consuming these drugs.
Anticholinergics: This medication is mainly used to counter tremors of the limbs in the early stage of Parkinson s disease.

Parkinson's Disease - Know The Risks Involved!

If you are being treated for Parkinson's disease. How can you maximize the effect of Levodopa? The effect of levodopa can be maximized by increasing its absorption from the digestive system. In particular, taking levodopa on an empty stomach is very important. 

Take on an empty stomach: Do not eat anything 1 hour before taking levodopa. Do not eat anything for at least 30 minutes and if possible 1 hour after taking it. Take the pill with 2 glasses of water so that it can dissolve. If taking the levodopa on an empty stomach makes you nauseous, confirm that your medication has the right amount of carbidopa in relation to the levodopa (25%). If you continue to feel nauseous, you can eat a piece of white bread around the time that you take levodopa. Do not apply any butter, yogurt, cheese or similar high protein spreads. Protein can drastically decrease the absorption of levodopa. 
Get your constipation treated: This is critically important too. Being constipated can slow down the passage of levodopa through the digestive system. In most patients, drinking adequate water and taking stool softeners is helpful. 
Get your ulcer treated: It can be difficult to recognize that you have a gastric ulcer. However, if you have a burning sensation in your stomach at any time, or belch frequently, you may have a gastric ulcer. If you think you have an ulcer you should get tested (there is a simple breath test now) and treated with antibiotics (not antacids!) 
Do not take levodopa with iron tablets: The iron binds to levodopa and prevents its absorption. Keep a gap of at least two hours between these two medications. 
Try taking levodopa with orange juice and carbonated water (soda): Mix equal quantities of orange juice and carbonated water (soda). Take your regular levodopa with a glass of this preparation instead of water. The carbonated water hastens disintegration of the tablet, and the acidity of both things helps in levodopa absorption. There are special tablets of levodopa (dispersible levodopa, Madopar) which can be dissolved in this preparation. Talk to your doctor about it.

Suffering From Parkinson's Disease - How You Can Maximise The Effect Of Levodopa? 

You might be aware that the Parkinson s diseases is related to the nervous system and is a progressive disorder that impairs movement. The cause of the illness is still unknown, but certain factors like environmental triggers and genetics may play a part in this regard. There are several myths about this condition that are prevalent among people. Some of them are listed below along with the facts.

Myth #1: Parkinson s disease occurs only in aged persons
This is one of the biggest misconceptions that people have about this disease. The misconception arises because the disease is usually diagnosed at an old age. But according to various researches that are conducted the disease may start developing at a younger age.

Myth #2: The disease symptoms include only impaired movement
Impaired movement maybe one of the biggest symptoms of the diseases but not the only one. There are other symptoms which affect day-to-day activities but are still unnoticed. These symptoms include constipation, sleep disorders, sweating, abnormal bladder functioning, fatigue, sexual dysfunction, cognitive symptoms, depression and even anxiety. But the symptoms that are non-motor are treatable unlike the problems with movement.

Myth #3: There is no hope for patients who are diagnosed with the disease
Patients who are diagnosed with Parkinson s disease are often told that they do not have any hope towards a cure. It is true that the disease is a progressive one, but it is not true that it cannot be controlled. Certain devices have been discovered which when used sends a signal to the brain which helps in reducing the tremors which are one of the well-known symptoms of the disease. So, no need to lose hope.

Myth #4: Medications are the only way in which you can undertake treatment for Parkinson s disease
Some people believe that they cannot do anything except for taking medications to control the disease. But this is not true. Doing regular exercise and changing your food habits are at many times helpful in treating this particular condition. Have a balanced diet which will have enough fiber is also helpful. To increase your stability and flexibility, a daily workout routine is quite recommendable, and it will even increase your self-confidence and your feeling of independence.

Myth #5: Everything about the disease can be predicted
The disease is not at all predictable. If it were, a cure would have been in place by now. Everything from the symptoms to the treatment procedure varies from person to person. The disease may take years to develop in one individual but may develop instantly in someone else.

Don t go by hearsay evidence about a disease. Medical science has improved a lot over the years. If you have any doubt regarding your health condition reach out to your doctor and clarify them at once.

5 Common Myths & Facts About Parkinson's Disease!

One of the common ailments in the elderly people is the Parkinson s. A progressive disorder, when left untreated, results in worsening of the symptoms. Hence, it is essential to understand the treatment options available to manage the condition effectively. You may be suggested surgical therapies if medication is not effective enough to treat the symptoms.

Surgical treatment options can be beneficial for patients who are suffering from symptoms, but they do not help with treating the disease. In the past, surgical methods like Thalamotomy and Pallidotomy were used to destroy brain cells that contributed to the symptoms. While these methods are still used, they are very rare and situational.

Deep Brain Stimulation (DBS), an FDA-approved procedure, has become much more popular as it is much safer and does not involve invasive surgery. Instead of destroying brain cells like traditional methods, DBS involves sending electric pulses to the affected brain cells to reduce the symptoms. It is not a treatment procedure, but a means of bringing down the severity of Parkinson s to allow better and more comfortable treatment.

Deep Brain Simulation   Who are the right candidates?
Deep Brain Simulation is commonly used for Parkinson  s disease, but it is not recommended for everyone. It is a preferred method of treatment for people who have had Parkinson s for at least four years but have complications which include long periods of time where medications do not work, or symptoms return, uncontrolled and involuntary movements or the freezing/stiffness in the body.

Deep Brain Simulation is not recommended for those who have Dementia as it can lead to memory problems. The general rule of thumb that neurosurgeons follow is that Deep Brain Simulation can help with symptoms that do not get better with medication. DBS can help reduce medication requirements for patients as well as reduce the side effects that may occur due to medication.

Disorder specialists and neurosurgeons can conduct tests to determine if DBS is going to be effective for a patient before going ahead with such a procedure. An extensive assessment is necessary to understand the symptoms, the effect of Parkinson's drugs and also brain imaging is done. All of the expected benefits are then evaluated for the patients, and if the procedure can help alleviate the symptoms, DBS is given a green signal by neurosurgeons and patients can undergo the procedure.

How Does Deep Brain Simulation Work?
Deep Brain Simulation is a very complex procedure. Brain cells communicate with the rest of the body through electric signal, and these become irregular and do not work properly when affected by Parkinson's. DBS smoothens the functioning of these brain cells and reduces symptoms through electric pulses through the implantation of a medical device known as neurostimulator which is also referred as brain pacemaker.

But, as with any treatment procedure, DBS has potential risks and side effects, hence discuss with neurosurgeon thoroughly to access the suitability.

Adopting Deep Brain Stimulation For Parkinson's disease

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