Addison s disease is known as adrenal insufficiency or hypocortisolism. It is a hormonal disorder which occurs when adrenal glands which are located just above the kidneys do not produce enough of the hormone. The hormones produced by adrenal glands include cortisol and aldosterone, which are essential for a healthy life.

The disease is characterized by weight loss, muscle weakness, fatigue, low blood pressure, and darkening of the skin also sometimes. Most cases of Addison's disease are caused by autoimmune disorders.
It is quite a rare condition. Only 1 in 1 lakh suffer from this condition. this condition can affect a person of any age group irrespective of sex. To live a normal life people, with this condition, a patient will be required to take their medication regularly.

Cortisol and Aldosterone - What do they do?
The most important function of the cortisol in the body is to respond to stress. It helps the body in using protein, carbohydrates, and fat. It maintains blood pressure, cardiovascular function; and controls inflammation. While as aldosterone helps kidneys in regulating the amount of salt and water in the body   which helps in regulating blood volume and keeping blood pressure under control.

Cause of Addison's Disease
Mostly Addison s disease occurs due to problems with adrenal glands themselves   which is known as primary adrenal insufficiency. While Autoimmune disease accounts for 70% of Addison s disease. In this condition, the body's immune system mistakenly attacks the adrenal glands. This attack destroys the outer layer of the glands.

Some long-term infections such as tuberculosis, HIV, and some fungal infections harm the adrenal glands. It is also caused by the cancer cells that spread from other parts of the body to the adrenal glands.
Less commonly, adrenal glands can also be affected by secondary adrenal insufficiency. It is caused by a problem with the pituitary gland or a problem with the hypothalamus, both located in the center of the brain.
These glands produce hormones that control the production of hormones in the rest of the body. A pituitary hormone called ACTH which turns on cortisol production in the adrenal gland. If ACTH levels are too low, the adrenal glands do not function.
One more cause of secondary adrenal insufficiency is also caused by the prolonged or abuse of steroid hormones such as prednisone.
Symptoms of Addison's disease
The symptoms of adrenal insufficiency grow gradually and the main characteristics are:

Chronic, worsening fatigue
Muscle weakness
Loss of appetite
Weight loss
About 50 percent of the time, one will notice:

Nausea
Vomiting
Diarrhea

A Quick Guide To Addison's Disease!

The adrenal glands, which sit above the kidneys, are very important to your body as they secrete many important hormones. These hormones are required to regulate many functions within the body. The two most important hormones that these glands produce are  cortisol  and  aldosterone . When your body suffers from the condition of Addison s disease, the glands end up producing very little amounts of these hormones. This will result in many functions in the body being adversely affected.


How do you know your loved one is suffering from Addison s disease?
Addison s disease develops overtime and doesn t happen immediately. However, you would be able to notice some of the following symptoms:
Drop in blood pressure which may result in fainting as well
Development of darker skin due to hyperpigmentation
Development of hypoglycemia or low blood sugar
Unexpected weight loss and a decreased appetite in general 
Craving for salt
Extreme fatigue
Irritability and depression
Vomiting, nausea and diarrhea 
Muscle and joint pains
Abdominal pains
Of these, if you start seeing a combination of frequent hyperpigmentation, muscle and joint pains, nausea, vomiting, abdominal pain, extreme fatigue and unexplained weight loss, you should take your loved one to the doctor immediately as these are telltale signs of Addison s disease.


Diagnosis
There are no ways to self-diagnose this disease as it requires proper medical tests. Some of the medical tests that may be advised for this are:
Blood tests: These are done to measure the levels of sodium, potassium and cortisol in your blood.
ACTH tests: This is a test to determine the exact levels of  cortisol  in your blood and whether it is being produced normally or not.
Hypoglycemia test: This is a test to measure whether adrenal glands are producing enough hormones to regulate insulin. If blood sugar is low, it will indicate problems with the adrenal glands.
Imaging tests: Other tests, such as CT scans may also be prescribed to detect problems within your adrenal glands.


Steps to manage Addison s disease 
Pay regular visits to your doctor: This is very important along with regular tests and checkups as other dependent functions may be damaged and suddenly become life threatening. It may fall on you to take your loved one to a doctor regularly for this reason.
Carry bracelets which have your medical information: If your loved one has a tendency to faint due to the problems caused by Addison s disease, it is important that you ensure they always carry bracelets with medical information with them. This way, strangers will be able to recognize the problem and get help quickly in emergency situations. 
Always keep extra medications: This is a very important point as missing a couple of daily doses and medication can result in sudden deterioration of your loved one's  condition. Have all other forms of administering medications handy as well such as syringes among others.

Addison's disease - How to Support a Loved One Suffering from it?

Can Exercise Help Control Blood Sugar Levels?

It is an established fact that regular physical exercise has wonderful effects on the overall health of a person. People of all ages can reap the benefits of exercise that take manifestation in all the various systems of the human body.

One such healthy effect of exercise is that it can help control blood sugar levels. For those who have been diagnosed with diabetes, exercise works like any other drug in keeping blood glucose at an optimal level. It also helps in preventing further health complications that may be caused by this condition, such as heart disease or strokes.

How does exercise control blood sugar?

Exercise affects the body's blood glucose levels in the following ways:

- Exercising increases insulin sensitivity, which makes the body more capable of using insulin to take up available excess glucose in the bloodstream.

- Muscle contractions during exercise stimulate the cells to use up glucose to produce energy.

- Heightened cardiovascular activity while exercising burns through blood glucose a lot faster.

It is necessary to keep checking blood sugar levels at regular intervals, especially if you suffer from diabetes. Working out has different effects on different individuals, depending on the duration and intensity of exercise and the overall health and medical history of the person.

What are the best ways to use exercise to reduce blood sugar levels?

It is important to chalk out a suitable exercise routine that is tailored specifically to your individual needs. Consult a health care specialist or physical therapist for formulating the best possible workout regime for your specific requirements.

Most experts recommend engaging in moderately intense exercise for a minimum of 150 minutes in a week.

A few examples of activities that fall under this category are as follows:

-Brisk walking
-Cycling
-Swimming
-Squats and lunges
-Stretching exercises
-Yoga

One thing that diabetes patients should always keep in mind is that over-exercising must be avoided. Excessively strenuous workouts can lead to hypoglycemia (deficiency of blood glucose) which is a highly unsavory condition.



Can Exercise Help Control Blood Sugar Levels?

Exercise has a considerable number of benefits to offer people who have diabetes. As a result of doing exercise on a regular basis, the blood sugar level stays in check. Managing diabetes without indulging in any physical activity is near to no good as exercise is the backbone of diabetes treatment. Here are the ten exercises that prove to be great for people with diabetes.

Walking: Walking is considered to be one of the best exercises for treating diabetes and the most prescribed physical activity for people with Type 2 diabetes. A daily brisk walking of at least 30 minutes can be the easiest way of increasing one s physical activity level.
Running/jogging: By jogging or running daily, people can control their blood pressure and ensure good heart condition. It proves to be extremely beneficial for diabetes people who often develop risks of heart attacks or high blood pressure.
Weight training: As regular weight training helps in building the muscle mass, opting for this becomes necessary for people with Type 2 diabetes. Because losing muscle mass means difficulty in maintaining the blood sugar levels.
Tai Chi: Tai Chi helps in relaxing the body and mind as well as ensures trouble-free body movements. Tai Chi plays a crucial role in reducing stress and nerve damage, which is a common complication in diabetes.
Swimming: Swimming helps in relaxing and stretching the muscles, without exerting any pressure on the joints, which is why it is a great exercise for diabetic people. Often diabetic people lose sensation in their feet, which makes swimming the best option for them.
Yoga: Helping in lowering the body fat, improving the nerve function, and fighting the insulin resistance, yoga can benefit people suffering from diabetes in a lot of ways. By controlling the stress, it indirectly helps in lowering the blood sugar levels.
Stationary bicycling: A form of aerobic exercise, stationary bicycling ensures a strong heart and well-functioning lungs. Burning lots of calories, it improves the blood flow to the legs, which is important for diabetic people.
Water aerobics: Water aerobics, too, has a lot of benefits to offer to the diabetic people in terms of regaining the right body balance and strengthening the muscles.
Playing: For those who enjoy playing tennis or basketball, treating diabetes with exercise can be an easy job. All one has to do is play rigorously on a daily basis, and the body will stay fit and the blood sugar levels well controlled.
Dancing: Dancing can be a great way of doing exercise for the diabetic people as it helps in improving the flexibility of the body, reducing stress and lowering the blood sugar levels.
By including exercise as a regular part of their daily life, people with diabetes can not only experience positive effects on their diabetic condition but can also achieve an overall good health with desired fitness.

10 Exercises That Will Surely Help Diabetic Patients!

Insulin is the most common treatment prescribed for people affected with diabetes. Diabetes is condition where high amounts of glucose prevail in the blood for an extended period of time. However, there are some drugs that offer an alternative to insulin in treating diabetes, which are:

1. Liraglutide: Liraglutide is a glucagon-like peptide-1 (GLP-1) drug that causes the body to release greater amounts of insulin so as to facilitate the movement of glucose from the blood to the cells. People with type 2 diabetes generally use this treatment. It slows the digestion process and can cause symptoms of headache and nausea. 

2. Pramlintide: It's an artificially produced version of amylin. It is taken by both type 1 and type 2 diabetic patients, facilitates slower digestion of food and therefore, controls release of sugar in the blood. It can cause tiredness and nausea.

3. Dulaglutide:This treatment is for people affected with type 2 diabetes and it is administered once a week. It causes more insulin to be released and pass the glucose to the cells. It can cause loss of appetite, nausea and abdominal cramps as side effects.

4. Albiglutide: This treatment facilitates pancreas to release insulin and limits the glucagon hormone production. It is used by type 2 diabetes patients who have not taken well to other treatments. The side effects are skin reaction, respiratory tract infection and nausea.

5. Exenatide: It is a drug that causes pancreas to release insulin that facilitates movement of glucose to cells. It is a treatment for type 2 diabetes and it restricts release of glucagon in the body. The possible side effects are acidity, constipation and vomiting.

Common Insulin Alternatives

Thyroid is a gland which is located in the neck right beneath the Adam s apple. The hormone produced by it is called thyroxin and this hormone is responsible for controlling the body s metabolic rate. This gland works as a thermostat for the human body as it controls other hormones which are responsible for burning and using calories.

How does it affect your life?

Hypothyroidism, also known as the  underactive thyroid disease , is a disorder which causes the thyroid to secrete insufficient hormone, thus causing the body s metabolic rate to slow down, and in turn affecting the heart rate and body temperature.
The people who suffer from hypothyroidism often experience weight gain and sensitivity to cold. Weight gain in case of hypothyroidism occurs despite having a low appetite. This is because the calories consumed are not burnt and used appropriately.
Fatigue is another major issue associated with hypothyroidism. Individuals suffering from hypothyroidism usually become tired after the first half of the day.
An underactive thyroid also causes drowsiness and depression. These may initially not seem to be major problems but in the long run, both the quality of life and overall health are usually negatively affected by it.
Thyroid related issues have become more common nowadays. Research shows that an unhealthy lifestyle is one of the major reasons behind this. Sedentary lifestyle involving little physical movement coupled with consumption of an unbalanced diet has led to surge in the number of such cases.
Doctors prescribe medications in case of hypothyroidism. But apart from medicines, simple modifications in lifestyle can go a long way in addressing this disorder. Research shows that consuming a healthy diet rich in iodine and comprising of sea food and green leafy vegetables, can increase the production of thyroxin in the body. Regular exercises must also be coupled along with following a proper diet.

Hypothyroidism - How It Affects Your Lifestyle?

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