Pancreas Transplant is a surgical procedure where the damaged pancreas is taken out of the body of the patient and transplanted with the healthy ones from the donor s body.
The pancreas is located in the middle part of the body that helps in the secretion of insulin in the body. Insulin helps in the absorption of sugar in the body and helps in maintaining glucose level. If the pancreas is not producing insulin in sufficient quantity than the patient is likely to suffer type 1 diabetes.

Most of the pancreas transplants are done to cure the extreme conditions of type 1 diabetes. However, the transplants are done only in case of severe diabetic conditions because the pancreas transplant has serious side effects and not always pleasant after surgery recovery.

Why is the Pancreas Transplant Done?
There are several reasons for doctors choosing for pancreas transplantation. One of the most reason is the type of diabetes. However, they are also performed along with the kidney transplantation, when damage to the kidney is done by diabetes.

Following reasons are worth considering for pancreas transplantation:
  Extreme and severe type 1 diabetes
  Kidney damage
  Type 2 diabetes due to a lower level of insulin usage in the body
  Poor blood sugar level

Types of Pancreas Transplantations-

  Pancreas Transplant Alone: The pancreas transplantation is done solely for the diabetic patient whose kidney is unaffected and does not require any surgery along with pancreas transplant.

  Pancreas Transplantation Along with Kidney Transplant: This kind of surgery is done by the doctors when the patient has weak kidney and damaged pancreas. In such a scenario, only kidney transplantation is not sufficient and requires new pancreas for overall development.

  Pancreas-after-kidney Transplantation: For patients who have been waiting long enough for a donor for pancreas and kidney both, this is a better solution. Since the waiting list to get, such donor is long and not probable. Doctors prioritize and perform kidney transplantation first since the condition for kidney transplantation is rather severe and affected. Then after pancreas transplantation is done when a suitable donor is found.

  Pancreatic Islet Cell Transplant: Pancreatic islet cells are responsible for producing insulin into the body. So, doctors perform surgery on the patient and inject the pancreatic islet cells from donor s pancreas to the patient under operation.

Complications of the Procedure-
Some of the common complications of the procedure are:

  Blood clots
  Bleeding
  Infection
  Excess sugar in the blood
  Failure of the donated pancreas
  Transplant rejection
  Urinary tract complications

Conclusion-
Pancreas Transplant is done when the patient is severely diabetic and is not curable with only medication. The doctors suggest the post-surgery rest. The patient is required to be hospitalized for one week at least and keep strict follow-up routine to look after the effects of transplantation.

Pancreas Transplant - When Is It Required?

The diagnosis as well as management of pancreatic cystic lesions is a general problem. Nearly 1% of the patients in the chief medical centers have been observed to have pancreatic cystic lesions on cross sectional imaging. It has also been observed that a quarter of all pancreas scanned in an autopsy series contain pancreatic cysts. Earlier, these cystic lesions were regarded benign but with increasing evidence made available from the cystic lesions, they are regarded as origin of pancreatic malignancies.


Information on asymptomatic neoplastic pancreatic cysts
The most vital medical tools that are used in the diagnosis and management of pancreatic cystic lesions include the endoscopic ultrasound and cross sectional imaging. These are used to distinguish non-mucinous cysts from mucinous cysts. The identification of pancreatic cysts creates a lot of anxiety for the clinicians as well as the patients related to the probable presence of a fatal tumor. The findings of a macro cystic lesion that enclose viscous fluid loaded in cea are helpful in the analysis of a mucinous lesion. 


The most common pancreatic cysts are the non-neoplastic inflammatory pseudo cysts, and they can be detected easily by imaging. The identification of pancreatic irregularity with probable association with malignant cells is a vital source of referral for the specialist. The set of guidelines that have been proposed for the management and diagnosis of patients with asymptomatic neoplastic pancreatic cysts are based specifically on the analysis of the quality of the data. It is also designed to address the most important and frequent clinical scenarios. The diagnostic suggestions are provided based on the clinical problem as well as the risk of malignancy.


Imperative guidelines to follow
To achieve accurate diagnosis of asymptomatic neoplastic pancreatic cysts is indeed a great challenge. It is all the more important to find the reproducible methods that can be used to stratify threat of cancer for the patients. The main guidelines include a two year screening interval of cysts that can be of any size as well as stopping observation after 5 years, in case there is no change. The new guidelines, for the most part, recommend surgery if more than one concerning feature is confirmed on the mri by use of endoscopic ultrasound. The new guidelines even suggest discontinuation of inspection after the surgery if no dysplasia or invasive cancer is identified. The guidelines have mainly been developed by use of grading of recomendations assessment, development and evaluation.

Diagnosis and Management of Asymptomatic Neoplastic Pancreatic Cysts

There has been an intense debate, which is in the loop for years and has been raging back and forth regarding the deficiencies of a vegetarian diet versus the perils of a non-vegetarian one. This heated debate is both accurate as well as unfounded. Probably, that s the entire reason it is still a debate. In fact, if you look into the diet of both groups, you will be able to identify the fact that, there is a space for healthy living in both.

Vegetarian Diet

In a vegetarian diet, the food intake of a person is confined to a large variety of foods derived from plants along with milk and dairy. And, any form of meat and products derived from animals are completely avoided.

Pros

Vegetarians have been noted to consume lesser amount of proteins, but they do not suffer from problems related to a high protein diet, such as osteoporosis (characterized by brittle and weak bones) and kidney failure.
The diet includes high level of antioxidants such as vitamin E & C as well as carotene, which is available in vegetables and fruits.
Additionally, they consume less amount of saturated fats.
Cons

Deficiency of vitamin B12 is common amongst vegetarians, as it is mainly available in meat, eggs and fish. Deficiency of vitamin B12 can yield rare symptoms such as increased fatigue, shortness of breath and a temporary loss of body balance.
Lack of protein, as stated above, along with iron and zinc deficiency is also common. 
Symptoms of protein deficiency can be troublesome and include signs like

Sluggish metabolism
Loss of body muscles (as the body tries to derive the regular protein intake from your muscles, thus making them weak),
Trouble gaining or losing weight
Persistent fatigue
Longer healing time in case of wounds and injuries
Pain in joints
Drastic changes in blood sugar level that might result in diabetes
A weak immune system makes you vulnerable to all kinds of diseases.
Non-vegetarian Diet

A non-vegetarian diet includes all forms of plant foods as well as foods and by-products that are derived from animals, such as poultry, fish, meat, etc.

Pros 

Vitamin B12 is present in adequate level since they are derived from sources such as meat, eggs and fish. Adequate intake of proteins is never an issue for  non-vegetarians
Cons

Meat products are loaded with saturated fats, which increase the risk of heart diseases. Studies have shown that people consuming non-vegetarian diets:
Have shorter lifespan and are more vulnerable to chronic diseases.
Tend to develop diabetes, heart diseases and hypertension.
Usually non vegetarians eat less amount of vegetables and fruits than what is recommended.  
If you wish to discuss about any specific problem, you can consult a Dietitian/Nutritionist.

Vegetarian vs Non Vegetarian Diet - Which is Better?

The inflammation of your pancreas over a short period of time indicates acute pancreatitis, which is a serious health condition. You may experience symptoms such as severe abdomen pain all of a sudden, diarrhoea and feeling of being sick. Acute pancreatitis occurs when there are some problems with certain enzymes in the pancreas. This condition is often associated with gallstones and alcohol consumption.


Treatment
Acute pancreatitis can be cured in a hospital, where you will get monitored for signs of serious issues. In some cases, supportive things like oxygen and fluids are required. Here are the various ways by which the condition can be treated:


1. Fluids: The body may get dehydrated during acute pancreatitis. Fluids are provided via a tube connected to one of the veins of the patient. This is known as intravenous or IV fluid. These fluids may help in the prevention of a problem called hypovolemic shock, which occurs when the amount of blood in your body gets lowered due to a drop in fluids. 
2. Nutrition: Diet is usually not restricted for people with acute pancreatitis, but some patients are recommended not to consume solid food for some time. Attempting to digest solid food may cause a strain on the pancreas. You may need to avoid solid food for some days. You should use a feeding tube to get essential nutrients. This process is called enteral feeding and it may involve the insertion of a tube into your stomach via the nose. 
3. Oxygen: For ensuring sufficient oxygen supply to your vital organs, you will be supplied with oxygen through the tubes on your nose. The tube may be removed when your condition improves. In some cases, ventilation equipment may be required for assistance to breathe.
4. Painkillers: Acute pancreatitis causes severe abdominal pain and strong painkillers such as morphine may be given to the patient. These may make the patient feel drowsy. 


Treatment of underlying cause
After controlling the symptoms, the underlying cause must be treated. They are as follows:
1. Gallstone: When pancreatitis occurs because of a gallstone, you may require a process known as endoscopic retrograde cholangiopancreatography or ERCP. The gallbladder may have to be removed, if necessary. 


2. Alcohol consumption: After getting treated for acute pancreatitis and you have recovered from this condition, you should try to avoid alcohol completely. Alcohol may spoil your recovery and the condition might reoccur or the symptoms may reappear. For freedom from alcohol, you may try counselling, joining self-help groups such as Alcoholics Anonymous (AA) or take a medicine which reduces your craving for alcohol. 


It is recommended that you visit a doctor immediately after experiencing any slight or severe symptoms of acute pancreatitis. This will help in early diagnosis and the chances of the symptoms getting worse are prevented.

Acute Pancreatitis - Can it be Cured?

The pancreas is a gland located in the abdominal region that performs two main functions for the body: produces digestive juices and the hormone insulin which regulates the blood sugar levels. The part which produces the digestive juices is exocrine and the insulin-producing part is the endocrine portion. Pancreatic cancer, which is an uncontrolled growth of the pancreas cells, often starts in the exocrine portion and is known as the pancreatic adenocarcinoma. The one which develops in the endocrine portion is known as neuroendocrine cancer or islet cell tumors.

Risk factors
Though not clearly established, the following factors are believed to up the risk of pancreatic cancer.

Smoking
Family history
Prolonged uncontrolled diabetes
Pancreatic conditions like inherited pancreatitis
Chronic inflammation of the pancreas
Symptoms
A pancreatic condition is of insidious onset, and the exact period of onset cannot be determined. The symptoms also are nonspecific abdominal symptoms, which do not pinpoint the pancreas per se.

Jaundice, which includes yellowing of the skin and whites of the white. This is because the growth of the pancreas puts pressure on the liver and bile ducts, and so hampers bile flow.
Weight loss, which was unintended. This is due to a bloated feeling plus inability to digest the foods.
Severe pain, which can be difficult and may even require regular injections to control.
Fluctuating sugar levels, which is unexplained.
Onset of diabetes, which is associated with weight loss and jaundice.
Increased tendency for blood clots.
Loss of appetite.
Bowel obstruction due to blockage of the growing pancreas.
Diagnosis
The above symptoms could lead to a further investigation that includes a few important tests, like the following.

Blood tests
Insulin levels
CT scan
Ultrasound
MRI
Laparoscopy, both to look for the extent of the disease and to do a biopsy, which can be used for confirming the type of cancer
Percutaneous transhepatic cholangiography: A dye is injected into the pancreas to study the spread of the dye, which will also help identify the diseased portion.
Treatment
Pancreatic cancer is very aggressive, usually not detected early, and has a very poor prognosis. So, if there is a family history or one has a prolonged pancreatic condition, it is advisable to go for annual screening to help with early detection and intervention. Once identified, treatment would include a combination of the three modalities   surgery, radiation, and chemotherapy. Surgery often may be followed by chemotherapy and/or radiation.

Prognosis
The prognosis for pancreatic cancer is very poor. Only about 25% of patients diagnosed with pancreatic cancer live past the first year. Early detection of risk factor remains the best way to improve prognosis. In case you have a concern or query you can always consult an expert & get answers to your questions!

Pancreatic Cancer - 8 Common Signs You Must Be Aware Of!

Diabetes which was earlier called a lazy person's disease does not live up to the name anymore. Owing to the sedentary lifestyle and bad eating habits, diabetes has become an epidemic in the recent years.
As as we all know, diabetes is a condition characterized by an increased concentration of blood glucose level. If not managed and treated on time, the condition can prove to be life threatening. Diabetes is known to trigger a host of health complications and disorders including cancer. In fact, research has established that there is a link between diabetes and pancreatic cancer. The report suggests that people with chronic diabetes for more than 5 years stand at an increased risk of suffering from pancreatic cancer. In some patients, diabetes may be one of the symptoms associated with pancreatic cancer. Whether diabetes triggered pancreatic cancer or was it the precancerous cells that caused the diabetes is difficult to explain.

The pancreas is an important organ involved in the production and secretion of many important hormones including the insulin (by the Beta cells of the pancreas). A diseased condition, such as pancreatic cancer may bring about changes, affecting the proper functioning of the pancreas. This, in turn, may interfere with the production of insulin. Decreased production of insulin or insulin resistance may result in elevated concentrations of glucose in the blood, a condition that will eventually give rise to Diabetes.

According to another published article (NCBI), in many patients with pancreatic cancer, diabetes was detected almost simultaneously along with cancer or 2 years prior to the diagnosis of cancer. These findings indicate the fact that both diabetes and pancreatic cancer not only occurred concomitantly but were also correlated.

Another experiment suggested that in people with Type-2 diabetes, the pancreas was for long subjected to a condition termed as hyperinsulinemia (increased level of insulin in the blood as compared to the blood glucose level). The experiment shows that insulin does have a role to play in establishing a relationship between diabetes and pancreatic cancer.

Managing Diabetes and Pancreatic Cancer
The conditions of diabetes and pancreatic cancer should be managed well to avoid further complications.

The diet plays a significant role in the proper management. The diet should be well balanced with all the essential nutrients. Include more fruits and vegetables in the diet. Berries such as raspberries, blackberries can go a long way to regularize the blood glucose level. Opt for whole grain cereals and food items. Avoid foods rich in fats and carbohydrates.
A healthy body weight can work wonders, both in the case of diabetes and pancreatic cancer. If you are a couch potato, give up the habit at the earliest. Indulge in more physical activities (not necessarily rigorous or strenuous) such as exercise, jogging, morning walk. In addition to keeping your weight in check, these physical activities are excellent stress busters.
The unhealthy lifestyle habits such as drinking, smoking, substance abuse can harm your body beyond imagination. Give up these unhealthy habits as early as you can.
There may be a strong connection between pancreatic cancer and diabetes. However, to avoid one affecting the other, one should take care of themselves and manage the conditions well.

Pancreatic Cancer - Are Diabetic Patients At A Higher Risk?

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