The pancreas is a gland located in the abdominal region that performs two main functions for the body: produces digestive juices and the hormone insulin which regulates the blood sugar levels. The part which produces the digestive juices is exocrine and the insulin-producing part is the endocrine portion. Pancreatic cancer, which is an uncontrolled growth of the pancreas cells, often starts in the exocrine portion and is known as the pancreatic adenocarcinoma. The one which develops in the endocrine portion is known as neuroendocrine cancer or islet cell tumors.

Risk factors
Though not clearly established, the following factors are believed to up the risk of pancreatic cancer.

Smoking
Family history
Prolonged uncontrolled diabetes
Pancreatic conditions like inherited pancreatitis
Chronic inflammation of the pancreas
Symptoms
A pancreatic condition is of insidious onset, and the exact period of onset cannot be determined. The symptoms also are nonspecific abdominal symptoms, which do not pinpoint the pancreas per se.

Jaundice, which includes yellowing of the skin and whites of the white. This is because the growth of the pancreas puts pressure on the liver and bile ducts, and so hampers bile flow.
Weight loss, which was unintended. This is due to a bloated feeling plus inability to digest the foods.
Severe pain, which can be difficult and may even require regular injections to control.
Fluctuating sugar levels, which is unexplained.
Onset of diabetes, which is associated with weight loss and jaundice.
Increased tendency for blood clots.
Loss of appetite.
Bowel obstruction due to blockage of the growing pancreas.
Diagnosis
The above symptoms could lead to a further investigation that includes a few important tests, like the following.

Blood tests
Insulin levels
CT scan
Ultrasound
MRI
Laparoscopy, both to look for the extent of the disease and to do a biopsy, which can be used for confirming the type of cancer
Percutaneous transhepatic cholangiography: A dye is injected into the pancreas to study the spread of the dye, which will also help identify the diseased portion.
Treatment
Pancreatic cancer is very aggressive, usually not detected early, and has a very poor prognosis. So, if there is a family history or one has a prolonged pancreatic condition, it is advisable to go for annual screening to help with early detection and intervention. Once identified, treatment would include a combination of the three modalities   surgery, radiation, and chemotherapy. Surgery often may be followed by chemotherapy and/or radiation.

Prognosis
The prognosis for pancreatic cancer is very poor. Only about 25% of patients diagnosed with pancreatic cancer live past the first year. Early detection of risk factor remains the best way to improve prognosis. In case you have a concern or query you can always consult an expert & get answers to your questions!

Pancreatic Cancer - 8 Common Signs You Must Be Aware Of!

Mango is one of the most loved fruits and is known as the king of all fruits. This fruit has different flavors along with fragrance and qualities that will prove best for the body in many areas. It is the seasonal fruit which is mostly found in tropics. It is the tress which is cultivated in different regions in India. It is the juicy fruit which has a unique taste that makes it different from other fruits.

Health benefits of Mango

It has antioxidant compounds and is rich in fibre, minerals and vitamins.
It is rich in potassium, which is best for the body and helps in the composition of cells along with body fluids that will help in controlling blood pressure and heart rate.
It is rich in vitamin B6 along with vitamin E and C. Vitamin C will help in developing immunity, which helps the body in fighting many diseases.
It contains some amount of copper that will help the body in producing red blood cells.
It is also rich in Vitamin A which is important for the skin and keeps the person s skin free from allergies or wrinkles.
Consumption of mango will help you to protect from lung and oral cancer.
It protects the women from breast cancer. Not only women, it protects men from colon and prostate cancer with the help of polyphenolic compound.
It helps the body in losing weight as it contains nutrients and vitamins which are best for the body. It also contains fibre which helps in the digestion process by burning many calories.
It is good for eyes; regular consumption will lead to good eyesight. It also prevents night blindness.
Mango is also used as a body scrub by mixing it with honey and milk. The application of this mix gives smoother and softer skin.
It helps in the reduction of kidney stones.
It is rich in iron, which is best for pregnant women as it increases the level of iron in the body which makes blood healthy.
It helps in controlling the cholesterol levels in the body.
Conclusion
The above-mentioned points are just some of the benefits a mango offers as fruit; there are many more. But before you consume this fruit, visit a general practitioner as they can guide you better because people with diabetes may have to restrict its consumption.

Mango - 13 Surprising Health Benefits Of It!

Pancreas Transplant is a surgical procedure where the damaged pancreas is taken out of the body of the patient and transplanted with the healthy ones from the donor s body.
The pancreas is located in the middle part of the body that helps in the secretion of insulin in the body. Insulin helps in the absorption of sugar in the body and helps in maintaining glucose level. If the pancreas is not producing insulin in sufficient quantity than the patient is likely to suffer type 1 diabetes.

Most of the pancreas transplants are done to cure the extreme conditions of type 1 diabetes. However, the transplants are done only in case of severe diabetic conditions because the pancreas transplant has serious side effects and not always pleasant after surgery recovery.

Why is the Pancreas Transplant Done?
There are several reasons for doctors choosing for pancreas transplantation. One of the most reason is the type of diabetes. However, they are also performed along with the kidney transplantation, when damage to the kidney is done by diabetes.

Following reasons are worth considering for pancreas transplantation:
  Extreme and severe type 1 diabetes
  Kidney damage
  Type 2 diabetes due to a lower level of insulin usage in the body
  Poor blood sugar level

Types of Pancreas Transplantations-

  Pancreas Transplant Alone: The pancreas transplantation is done solely for the diabetic patient whose kidney is unaffected and does not require any surgery along with pancreas transplant.

  Pancreas Transplantation Along with Kidney Transplant: This kind of surgery is done by the doctors when the patient has weak kidney and damaged pancreas. In such a scenario, only kidney transplantation is not sufficient and requires new pancreas for overall development.

  Pancreas-after-kidney Transplantation: For patients who have been waiting long enough for a donor for pancreas and kidney both, this is a better solution. Since the waiting list to get, such donor is long and not probable. Doctors prioritize and perform kidney transplantation first since the condition for kidney transplantation is rather severe and affected. Then after pancreas transplantation is done when a suitable donor is found.

  Pancreatic Islet Cell Transplant: Pancreatic islet cells are responsible for producing insulin into the body. So, doctors perform surgery on the patient and inject the pancreatic islet cells from donor s pancreas to the patient under operation.

Complications of the Procedure-
Some of the common complications of the procedure are:

  Blood clots
  Bleeding
  Infection
  Excess sugar in the blood
  Failure of the donated pancreas
  Transplant rejection
  Urinary tract complications

Conclusion-
Pancreas Transplant is done when the patient is severely diabetic and is not curable with only medication. The doctors suggest the post-surgery rest. The patient is required to be hospitalized for one week at least and keep strict follow-up routine to look after the effects of transplantation.

Pancreas Transplant - When Is It Required?

There are many food items which would become stale after a few hours, but there are certain foods which may last forever without the need to can them or freeze or dehydrate. If an individual is new to the field of food storage, these staples can be an excellent way to begin.

White rice: There are numerous researchers who have found that polished or white rice keeps up their nutrient content and flavour for almost 30 years if it can be stored in oxygen-free containers in temperatures that range below 40 degrees Fahrenheit. Brown rice, on the other hand, doesn t last more than six months owing to the availability of natural oils in the bran layer.
Honey: Honey is preferably the only food that would last forever due to the perfect chemistry and the handiwork of the bees. The nectar extracted from the flower gets mixed with the enzymes present in the bees  bodies which alter the composition of the nectar. The nectar is further broken down into simple sugars and is accumulated in the honeycombs. The processing, as well as sealing of the honey, is primarily responsible for the incredible shelf life.
Salt: Since sodium chloride is a mineral which is taken from the natural components of the earth, its shelf-life should come as a natural consequence. It is used for centuries as a means of preserving other food products as it can extract out all the moisture. But this doesn t indicate that the table salt would last forever. Experts say that the addition of the iodine to the table salt reduces the shelf life of the salt which means that if the label says that it is an iodized salt, it will not last over five years.
Soy sauce: When left unopened, a container filled with soya sauce would last for a significantly long period. But it is also dependent on the type of soy sauce and the additives used. Even if the soy sauce has been opened, this salty condiment will last for many years if stored in the refrigerator.
Sugar: Quite similar to many items, the storage process of the sugar determines whether the sugar is going to last for long or not. Granulated and powdered sugar must be kept under an airtight condition to steer clear of moisture. Although retailers are needed to provide the manufacturing dates of the sugar, manufacturers say that the sugar remains edible even if it has hardened and become brown.
Pure maple syrup: Pure maple syrup, as well as commercial sugars such as granular sugars and honey, has an irresistible life owing to its shield against any kinds of microbial growth. Unopened maple syrup shall last forever, and in case there is the formation of mould, boiling it to a certain degree and skimming the surface and ultimately pouring it to a clean and air-tight container would eliminate all the problems.
Clarified butter: This kind of butter is boiled unless the total moisture is extracted which is the reason that it doesn t go bad. As long as the clarified butter or ghee is stored in sealed container under cool temperature, it would last for about 100 years.

7 Foods That Never Expire!

Pancreatic cancer is an aggressive form of cancer. The disease shows no early symptoms and often spreads to other organs long before it is properly diagnosed. Due to such poor prognosis, only around 6% of the pancreatic cancer patients are healthy and alive 5 years after the first diagnosis.

One of the most common surgeries to remove tumours from the pancreas is Pancreaticoduodenectomy, that is commonly called Whipples surgery. The primary aim of the procedure is to cure cancers or disorders that are identified in the pancreas, bile duct or the duodenum. Here, the tumour is removed to prevent it from spreading to other organs, thus improving the life expectancy of the patient. 

Whipple's Procedure

Before the surgery, an intravenous line will be injected to your arm, to provide you with the necessary medication. Medicines may be passed through this line to soothe your nerves. A spinal injection or an epidural catheter may be placed. This helps you to recover painlessly after the surgery.

The surgery can be carried out in different ways  

Open surgery

Here, the surgeon makes a small incision in your abdomen to access the pancreas and other organs. This is the most common method. This is a complicated operation where the tip of the pancreas, the gallbladder, the bile duct and the initial portion of the small intestine are removed. It is performed to treat cancers that are present on the head of the pancreas. 

Laparoscopic surgery

Here several small incisions are made in your abdomen to insert a camera that transmits the live video of the abdomen to a monitor. According to the live feed, the surgeon performs the operation by using surgical tools. It is a common form of minimally invasive surgery.

Robotic operation

This is another type of minimally invasive surgery where the surgical tools are attached to a special robot. Here, the doctor uses a console to control the robot to perform the surgery. This is used because surgical robots can reach and operate in spaces and corners where the human hands may not reach during surgery.

 The Whipples surgery can take 4 to 12 hours depending upon the approach being used and the complexity of the process. During the surgery, you will be given general anaesthesia, so you will be asleep.

In some cases, a part of your stomach or nearby lymph nodes may be removed to treat the cancer growths. After the process, the doctor will reconnect the other organs so that you can digest food normally.

After the procedure, you may face problems while emptying your bowels. The condition improves around 7 to 10 days after the surgery. Most patients are able to return back to their normal life usually around 6 weeks after the procedure.

It is recommended that you follow the doctor s instructions after the surgery and stick to the diet prescribed. Additionally, keep the incision protected from sunlight and remove the bandages only after consulting the doctors. 

 

 

Whipples Surgery & Pancreatic Cancer - Know About Them!

Pancreas is a small organ that is located in the lower part of the stomach. It lies just behind the abdomen. It functions by producing the insulin hormone which is responsible for regulating blood sugar level in the body and breaking down food into glucagon which is stored in the body. This glucagon is converted into glucose which is used by the body for energy and other purposes. Therefore, pancreatic transplant is done in patients with a malfunctioning pancreas.

Why is pancreatic transplant required?
Patients suffering from type I diabetes usually undergo a pancreatic transplant. Type I diabetes is characterized by the inability of the pancreas to produce insulin, thereby leading to low blood sugar level. This type of diabetes occurs due to the malfunction of pancreatic beta cells whose primary role is to produce insulin. These beta cells make up around 65 to 80 percent of the cells found in the pancreatic islets. They typically malfunction when the body's immune system begins to attack and destroy the pancreatic beta cells. Therefore, type I diabetes is an autoimmune disorder. Patients with type I diabetes require insulin injections that might cause severe reactions. People dependent on insulin are prone to the development of diabetic retinopathy and diabetic nephropathy.

People with type II diabetes generally do not need pancreatic transplant because this type of diabetes occurs due to low production of insulin or lack of insulin resistance. Here is a list of the probable reasons why pancreatic transplant is required:

People who have type I diabetes but are not cured by standard treatment
Severe reactions to insulin injections
Low blood sugar
Kidney damage
Hypoglycemia unawareness
A pancreatic transplant can be of three types. They are:

Pancreas transplant only- People with type I diabetes and normally functioning kidneys require only a pancreatic transplant.
Pancreas and kidney transplant- Type I diabetes, in rare cases, leads to end-stage renal disease (ESRD) or end-stage kidney disease where one or both the kidneys are damaged. In such cases, pancreas and kidney are transplanted simultaneously to disable the dependence on insulin injection. This type of surgery may also be required when the pancreas and the kidneys come from the same donor.
Pancreas-after-kidney transplant- In some cases of type I diabetes, your doctor will recommend kidney transplant first followed by pancreatic transplant. It must be remembered that pancreatic transplant should be done by taking into consideration the side-effects caused by the anti-rejection injections administered after the procedure is performed. It may cause bone thinning, high cholesterol and high blood pressure in a patient s body. As the anti-rejection injections work by suppressing the immune system, the body s defense mechanism against infections and other diseases becomes ineffective to a considerable extent.
A pancreatic transplant is a serious procedure that requires a lot of deliberations and consultations with your doctor and should only be opted for when the benefits outweigh the side effects from the anti-rejection medications.

Pancreatic Transplant - When Is It Required?

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