The primary aim of the treatment in patients suffering from seizure is leasing a seizure-free life without giving way to any adverse effects. This goal can be accomplished in over 60 percent people with the help of anticonvulsants. Some patients also experience adverse effects since they suffer from a seizure which is refractory to medical therapy. Here are some of the common treatment options for seizures:

Monotherapy: Sometimes, monotherapy is given as it reduces the chance of all sorts of adverse effects and even avoids drug interactions. Moreover, this type of treatment approach is much less expensive than polytherapy since many older generation of the anticonvulsant agent comprises of hepatic enzyme which is responsible for reducing the serum level of the concomitant drug which leads to an increase in the dosage level of such medicines.
Social And vocational rehabilitation: People suffering from problems in psychosocial adjustments after the diagnosis may also need social and vocational rehabilitation. Many physicians do not pay enough attention to the consequences that an epilepsy diagnosis may leave on the patient. For instance, people with epilepsy may have a fear of experiencing next attack of seizure and they may be unable to work at heights or drive.
Consulting an expert: It is important to refer patients with intractable spells to epileptologist or neurologist for subsequent workup. A neurosurgical consultation may also be needed when the patient has to be treated surgically.
Importance Of anticonvulsant therapy
Patients who have had already suffered from recurrent attacks of unprovoked seizure may need treatment with an anticonvulsant. This treatment is not recommended until the person has risk factors for suffering from the problem yet again. The primary means of treating seizure is anticonvulsant therapy where the most suitable drug is chosen based on accurate diagnosis of the syndrome as a response to specific anticonvulsants may vary from one patient to another. The difference in response may reflect the various pathophysiologic mechanisms in different types of seizures.

Types of anticonvulsant therapy
Some of the anticonvulsant therapy medication may have multiple action mechanism while some have an only single mechanism of action. Some of the most common variants of the therapy include:

Neuronal potassium channel referred to as KCNQ opener
Blockers of unique binding sites such as perampanel, gabapentin, and levetiracetam
H-current modulators such as lamotrigine and gabapentin
Carbonic anhydrase inhibitors such as zonisamide and topiramate
Alpha-amino 3-hydroxy 5-methyl 4-isoxazole propionic acid receptor blockers like topiramate and perampanel.
N and L-calcium channel blockers like zonisamide, valproate, topiramate, and lamotrigine
Even though there are so many types of drugs available, all of them cannot be used for the treatment of seizures. Doctors would evaluate the condition thoroughly before prescribing a medication that can be helpful in reducing the severity of the condition.

Seizures - 3 Ways It Can Be Treated!

How many of us have heard about Extracorporeal Membrane Oxygenation (ECMO) before Tamil Nadu, Chief Minister late J Jayalalithaa was put on it for recovery? Hardly a handful. Patients who are placed on the device have 50-50 chance of survival and while it could not help the late Chief Minister, her condition put a spotlight on ECMO.

What is ECMO?
ECMO is a life support device that is put in place when a patient's heart and lungs stop functioning completely post a cardiac arrest. When the patient does not respond to Cardio Pulmonary Resuscitation (CPR), the patient is put on ECMO.

Function of ECMO
The core function of the device is to separate carbon dioxide from the blood and add oxygen into it. It takes the load off from heart and lungs, providing critical time to the body organs for its treatment and recovery.
Patients are only put on ECMO, if there is a chance that the condition can be reversed.

How does ECMO work?
The device drains blood from a vein, which is attached to an oxygenator machine. The machine then removes carbon dioxide from the blood and adds oxygen to it. Depending upon the condition of the patient, the warm blood is either pumped into the body with the help of the machine or is transferred back into the body through an artery.

How long a patient can be on ECMO?
After seven days of being put on ECMO,there are chances of patient getting an infection.
In case the patient contracts an infection, it is recommended to take the patient off ECMO support.

All About ECMO - Extracorporeal Membrane Oxygenation 

One of the most common diseases that afflict a large section of the population is arthritis. It is common among people who are above 40 years of age. Acute joint pain, difficulties in movement and weakened bones are among the most common symptoms of arthritis. Given the fact that it is a condition that has permeated into modern life so deeply is what makes arthritis one of the most feared illnesses of this time. Although there are multiple forms of arthritis, there are primarily two types, which are:

Osteoarthritis: This is characterized by a breakdown of the cartilage between the bones. It is mostly known to affect a person s joints.
Rheumatoid Arthritis: This is a form of auto immune disease that severely affects the lining within the joints of bones.
Causes
The causes of arthritis might vary from person to person. Some of them are discussed below:

Diet and nutrition habits: Some food items, especially red meat and products derived from animals can cause a rise in the level of uric acid thus, increasing the risks of arthritis as well as gout. Smoking also has been known to worsen this condition.
Genetic predisposition: Some people are more prone to develop arthritis as they are genetically predisposed to it.
Problem in the immune system: Rheumatoid arthritis is one condition which is caused by the attack of immune system on the lining of the joints within the body.
Risk factors for arthritis include:

Obesity: The joints are subject to excess stress because of the excess weight. This results in a higher risk of arthritis in obese people.
Age: The risk of arthritis increases with age.
Family history: It is possible for you to be vulnerable to this disorder if arthritis runs in the family.
Previous injury: People who have had a previous joint injury are more susceptible to arthritis.
Typical symptoms of both forms of arthritis are:

Redness in the affected areas
Stiffness in the joints
Pain in the joints of the body
Swelling in particular joints or most joints of the body
Decreased mobility either due to pain or stiffness

Can Poor Diet and Nutrition be a Cause of Arthritis?

Being a victim or witnessing a horrific accident or personal assault can leave you shocked and scarred. Sometimes, these conditions last for months and years with memories of the traumatic incident triggering intense emotional and physical responses. This is known as post traumatic stress disorder or PTSD. It is a fairly common anxiety syndrome and can be treated in a number of ways including drugs, exercise and psychotherapy. However, this treatment aims only to control the disorder and there is no known cure for PTSD as yet.

Exercise not only keeps the body fit, but also helps the body release endorphins. Endorphins help fight stress, fear and pain. Thus, exercising helps focus on the body and its movements instead of your fears. It can also help elevate the mood of a person. Low to moderate intensity exercising is ideal for a PTSD patient. Aerobics, pilates, yoga or martial arts like tai chi are known to be effective ways of reducing stress and anxiety in PTSD patients. Breathing exercises like pranayama can also help calm and relax the mind.

Exercise for a PTSD patient should be planned in repetitive sets. This enables the person to slowly master the type of exercise being done and regain control and confidence in himself. It also needs to be predictable so as to avoid triggering a PTSD emotional or physical response. Non competitive exercises are better than competitive exercises as it does not create an opportunity for the person to feel stressed. Exercising and practicing breathing techniques can also help a person analyze himself and his response to stressful situations. By understanding their reactions, a person can slowly bring about changes to handle stress in a better way.

For a PTSD patient, exercise should not be seen as a group activity but as an individual effort to increase self control. Patience is key here both for the patient and the therapist. It is also necessary for the person to have realistic goals from his exercise regimen. An exercise program for PTSD patients also needs to be flexible. In order to meet the needs of a patient, it may need to be changed in accordance to the medication he is under. Small incidents like having a flat tire when cycling can trigger anxiety in a person suffering from PTSD. However, if dealt with correctly, it can bolster confidence in the long run.

Lastly, exercising also helps improve self-image and build confidence which helps a PTSD patient break out of his protective shell and socialize with others.

Post Traumatic Stress Disorder - How Exercising Can Help You Overcome?

The bones and joints orchestrate very well with each other for smooth movements of various joints and the spine. However, due to various reasons, some identified and others unknown, there could be inflammation of the areas where the bones join the muscles leading to impaired movement. The range of motion could be reduced or it could be painful, thereby, limiting movement. Spondyloarthritis includes a group of inflammatory diseases that involves the bones and joints and enthuses which are areas where the ligaments and tendons attach to the bones. This causes conditions like plantar fasciitis, ankylosing spondylitis, psoriatic arthritis and reactive arthritis. The term spondyloarthritis is a blanket term to describe any of the above-mentioned conditions.

Read on to know a little more in detail about it:

Causes: While the exact etiology is not identified for sure, most patients with spondyloarthritis have an autosomal dominant gene (HLA-B27). Chronic infections could trigger the onset of the disease too.

Symptoms:

1. In all forms of spondyloarthritis, there is always inflammation of the spine, joints and entheses. If the fingers or toes are involved, there could be swelling leading to what are typically known as 'sausage digits'.

2. There is sacroiliitis which is inflammation of the joint between the pelvis and the spine, and spondylitis which is inflammation of the joints between the spines. 3. Family history and autosomal dominant gene.

Diagnosis:

A detailed medical history and physical examination form the cornerstone of a confirmed diagnosis. In addition, radiographic examination and diagnostic blood tests also could be done to confirm the diagnosis. Radiographs, especially, of the spine and the low back show typical changes including sacroilitis in suspected cases of spondyloarthritis. If the spine does not show these changes, but there is a high likelihood of spondyloarthritis, then MRI (magnetic resonance imaging) can be used to confirm the diagnosis.

As a final step, a blood test for the HLA-B27 gene can also be confirmatory. However, it is not true that a person with the gene will definitely develop the disease.

Treatment:

The most important aspect of treatment is the use of pain medications and anti-inflammatory drugs (NSAIDs) which help manage pain and inflammation.
Corticosteroid injections may sometimes be given directly into the joint spaces or the membranes to provide quick relief of these symptoms.
ESWT / RSWT has a definite role to cure enthesopathy. Plantar fasciitis, and achillodynia can be cured with ESWT. Even small joints of hand and feet are amenable to treatment with RSWT. It is nonoperative and noninvasive treatment and has no side effects.
Very rarely, stronger drugs such as methotrexate or sulfasalazine may be used.
Another set of drugs known as TNF-blockers (tumor necrotizing factor blockers) are also shown to be highly effective in controlling the pain of the spine and joints.
In very severe cases, surgery may be required to correct joint damages or correct severe degenerative changes.
Exercise plays a very vital role in controlling the issue and improving range of motion.

What You Should Know About Spondyloarthritis?

Nuts and dry fruits are probably the oldest and traditional superfoods which our mothers have diligently offered us for our good health. Packed with proteins, iron, magnesium, healthy fats, vitamin B and fiber, these nutritional powerhouses are a must in our diet, but only in a limited quantity. Yes, taking almonds, dates, cashews, pistachios, and walnuts in excess amount can lead to excessive body heat, giving rise to nasty pimples and rashes. Not more than 2 tablespoons of dry fruits are recommended in a day because of their sugar content, they can easily help to put on weight by adding excess calories.

But, how true is the claim or is it a myth? Let's find out.

Here is a brief overview of how overconsumption of dry fruit is detrimental to health:

Weight gain: Studies conducted by researchers over the years has revealed that it takes over 3500 calories to gain 1 pound of weight. However, consuming just 250 calories from dry fruits can result in over 2 pounds of weight in a single month. A sudden increase in weight can bring in other complications such as obesity, menstrual problems in women, high blood pressure, etc. It is therefore imperative to avoid excess intake of dry fruits. To ensure minimum intake of calories, we could focus on dates, apricot, cranberries, blueberries, etc.
Asthma: Sulphur dioxide is often used to process dry fruits. Studies revealed that this foul-smelling gas isn t very harmful when consumed in limited quantities. But, as per food safety experts, the permissible limit of Sulphur dioxide in humans should not be more than 20 mg per day as it can cause asthma, allergic reaction and skin rashes in an individual.
Gastrointestinal problems: Food items with high fiber content help in regular bowel movement and smooth blood flow. However, consuming too much fiber can lead to bloating, diarrhea, flatulence, cramps and constipation. This is exactly the case with dry fruits as well. They contain fiber and have the capacity to wreak havoc in the intestinal lining on overconsumption. Gradual and steady consumption of dry fruits over a period of time can mitigate this risk. 
Tooth decay: Dry fruits that are available in the market come with a thick coat of sugar so that they do not infuse moisture and stick to each other. This sugar significantly contributes to tooth decay. This is the reason why overconsumption of dry foot should be avoided.
Sugar crash: Most dry fruits have a high glycaemic index which can quickly surge blood sugar levels and spike energy levels. Therefore, patients suffering from high pressure should strictly refrain from dry fruits.
While the cons appear frightening, do not cross the nuts off the grocery list completely. Dry fruits when consumed under control, can be really helpful. So remember that moderation is the key. And in case you have a concern or query you can always consult an expert & get answers to all your questions!

Dry Fruits - 5 Reasons Why You Must Not Eat Too Many!

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