In recent times, the advancement of medical science has substantially contributed in comprehending the Alzheimer s disease. Unfortunately, the number of individuals suffering from the disease is expected to rise in the next ten years which pose a threat to the allocation of health care resources and public health. Alzheimer s disease is thought to be a complex disease which influences a person s behavior as well as cognition through numerous mechanisms.

Can surgery be deemed as a treatment for Alzheimer s disease?
The surgery is a multicenter clinical trial which is making a new direction in clinical research. It is devised to halt or slow down the problems caused by the disease which gradually erases a lifetime of memories in elderly patients. Though there is no cure for Alzheimer s disease, it has been found that low-voltage electric charges delivered right at the brain. Only the symptomatic therapies for Alzheimer s disease are provided which do not have any effect on the evolution of the disease. The standard medical treatments for Alzheimer s disease include cholinesterase inhibitors along with a partial N-methyl D-aspartate antagonist. In most cases of mild to moderate symptoms of this disease, a combination of treatments is used according to the clinical history, age and condition of the patient.

Mental activity supporting cognition
Many patients having normal cognition or mild impairment have a fear that they may develop AD. Many experts are of the opinion that mentally challenging activities including brain teasers and crossword puzzles can be helpful in reducing the risks in such patients. Clinical trials are under the way for determining whether or not these types of activities have any substantial effect on halting the progression of AD.

Treating AD in its moderate to the severe stage
Numerous studies have shown that blockade of NMDA receptors by memantine can be used safely in combination with ChEls. This combination has been shown to delay the institutionalization in patients with Alzheimer s disease.

Treating secondary symptoms
A variety of behavioral as well as pharmacologic interventions can help in overcoming the clinical manifestations of the disease. These include anxiety, psychotic behavior, depression and agitation among others. The effectiveness of this disease can range from modest to excellent. No particular agent or dose of it can be unanimously accepted to be the sole treatment option for the wide range of clinical issues. Moreover, in the recent time, the FDA has not accepted any psychotropic agent for treating AD.

Along with these treatment options, there are behavioral interventions that can range from patient-centred approaches to caregiver training for helping manage the cognitive and behavioral manifestations of Alzheimer s disease. Last but not the least, it is very crucial to point out the significance of treatment in the early stages of AD in order to cure it better.

Alzheimer's Disease - Can Surgery Help You Treat It?

Cerebral palsy is a neurologic condition that occurs in children, and is due to brain injury that develops before, during, or after childbirth. The condition presents with motor impairment, and therefore there is generalized physical and mental dysfunction. The brain continues to develop for the first two years of life, and so conditions like premature birth, asphyxia at birth, and postnatal meningitis and encephalitis.

The diagnosis could be trigged by the slow motor development, poor muscle tone, and delayed response of the baby. One of the main noticeable feature that becomes evident is the spasticity of the limbs. The child may not be able to voice it out, but pain is a significant disabling factor too. While doctors would advise that physical movement is required to keep the spasticity at bay, the pain keeps the child away from most activities. This further adds to the spasticity and worsening of the condition.

Pain control therefore assumes a significant role and the modes can range from physical therapy to pain killers to injections to surgery. The idea, in addition to pain control, is also to:

Improve range of motion
Improve motor response
Promote good motor development
Reduce and control contractures
Improve overall lifestyle
Improve muscle strength
Improve exercise tolerance
Reduce spasticity
Some of the non-medical ways to control pain are listed below. 

Of course, pain killers and injections are always used when immediate relief is required. A structured physical therapy program that includes medications and exercise is the best way to manage cerebral palsy pain. Though initially difficult, over a period of time, it improves range of motion and improves joint movement.

Acupuncture: Triggering specific points via needles is believed to stimulate the nerve endings and help in pain control
Alternating ice and heat therapy: This is also believed to improve pain control, blood circulation, and muscle movement.
Positioning in bed: A well-positioned child in bed may have less pain compared to another child who is not. Special equipment may be used also to keep the child in place, once the most comfortable situation is located.
Muscle massage: The affected muscles need to be massaged repeatedly so that blood flow improves, joint movement is better, and pain is controlled.
Botox is successfully used to pain control, as it paralyzes the specific muscles along with providing pain control.
Medications are used regularly, which are mainly anticholinergic and anti-spastic medications. They reduce stiffness, control pain, and help in pain control too.
Surgery is the last option and needs to be explored with the doctor.

Pain Management Of Spasticity With Cerebral Palsy!

The primary aim of the treatment in patients suffering from seizure is leasing a seizure-free life without giving way to any adverse effects. This goal can be accomplished in over 60 percent people with the help of anticonvulsants. Some patients also experience adverse effects since they suffer from a seizure which is refractory to medical therapy. Here are some of the common treatment options for seizures:

Monotherapy: Sometimes, monotherapy is given as it reduces the chance of all sorts of adverse effects and even avoids drug interactions. Moreover, this type of treatment approach is much less expensive than polytherapy since many older generation of the anticonvulsant agent comprises of hepatic enzyme which is responsible for reducing the serum level of the concomitant drug which leads to an increase in the dosage level of such medicines.
Social And vocational rehabilitation: People suffering from problems in psychosocial adjustments after the diagnosis may also need social and vocational rehabilitation. Many physicians do not pay enough attention to the consequences that an epilepsy diagnosis may leave on the patient. For instance, people with epilepsy may have a fear of experiencing next attack of seizure and they may be unable to work at heights or drive.
Consulting an expert: It is important to refer patients with intractable spells to epileptologist or neurologist for subsequent workup. A neurosurgical consultation may also be needed when the patient has to be treated surgically.
Importance Of anticonvulsant therapy
Patients who have had already suffered from recurrent attacks of unprovoked seizure may need treatment with an anticonvulsant. This treatment is not recommended until the person has risk factors for suffering from the problem yet again. The primary means of treating seizure is anticonvulsant therapy where the most suitable drug is chosen based on accurate diagnosis of the syndrome as a response to specific anticonvulsants may vary from one patient to another. The difference in response may reflect the various pathophysiologic mechanisms in different types of seizures.

Types of anticonvulsant therapy
Some of the anticonvulsant therapy medication may have multiple action mechanism while some have an only single mechanism of action. Some of the most common variants of the therapy include:

Neuronal potassium channel referred to as KCNQ opener
Blockers of unique binding sites such as perampanel, gabapentin, and levetiracetam
H-current modulators such as lamotrigine and gabapentin
Carbonic anhydrase inhibitors such as zonisamide and topiramate
Alpha-amino 3-hydroxy 5-methyl 4-isoxazole propionic acid receptor blockers like topiramate and perampanel.
N and L-calcium channel blockers like zonisamide, valproate, topiramate, and lamotrigine
Even though there are so many types of drugs available, all of them cannot be used for the treatment of seizures. Doctors would evaluate the condition thoroughly before prescribing a medication that can be helpful in reducing the severity of the condition.

Seizures - 3 Ways It Can Be Treated!

There are various neurodegenerative disorders and Huntington Disease is one of them. It is characterized by loss of thinking ability, chorea or uncontrolled writhing and jerking movements, and psychiatric difficulties. 

Nerve cells in the brain are impaired in this disease. This leads to loss of coordination and involuntary movements. As the disease progresses, patients slowly fail to control their throat and mouth muscles and simple tasks like eating, swallowing, and speaking becomes challenging.

Huntington's Disease may also affect the reasoning and thinking abilities of an individual and makes communication and conversations more challenging. The problem of swallowing food can lead to choking as food can go down the wrong way or a lung infection in more severe cases. 

Speech-Language Pathologist or Speech Therapist helps the patients with speaking and swallowing problems with the help of various therapies.

Visiting a Speech-Language Pathologist in the initial stage of Huntington's Disease is advised. This helps in planning in advance about the ways to handle changes as the disease progresses. The therapist can help the patients when they begin showing an inability to speak or understand and swallowing problems. The symptoms showing swallowing difficulties may include choking, coughing and altered eating habits of the patient and loss of weight.

Symptoms

Dysarthria, in which the ability to remember words, understanding and forming a sentence is not lost but clear speech becomes difficult.

Stammering.

Slow or imprecise speech.

Aphasia, inability to understand what is being said and inability to remember grammar and vocabulary, and the pattern of losing a word in between the sentences.

Weak voice or low volume because of respiration issues.

Scanned Speech or unusual lengthy pauses between words.

Problem with pitch control and resonance.

Treatment

The progression of Huntington s disease varies from patient to patient and the therapy also varies as per the needs and challenges of the patients. The therapy usually starts with the discussion of problems and symptoms faced by the patients. 

For swallowing difficulties, patients may be recommended to maintain a journal of swallowing problems and fixing a time for meal intake every day. He/she may be recommended to eat soft food items, and eat slowly and chew the food properly.

As for speech therapy, one may be recommended breathing exercises. The therapist may demonstrate the patients how to overemphasize certain mouth movements to make the words easier to understand. The family of the patient is advised to reduce distraction while communicating with the patient. 

Assistive devices can also help with communication such as computers, smartphones or tablets. Other low-tech objects from everyday life, such as calendars, picture boards with a depiction of daily life activities, and object images and notebooks can also be helpful.

Take Away
Huntington Disease is a brain disorder where it becomes difficult for a person to control mouth muscles. In this, speaking, swallowing, and eating becomes a task for them. There are speech therapies that can help the patients to gather control over their words and communication problems.

 Huntington's Disease - How Effective Is Speech Therapy In It?

Dementia refers to the progressive loss of memory in a human being. It does not refer to any particular disease. It is rather a cumulative representation of symptoms which signify that the person is losing his or her memory. Dementia occurs in seven stages. Read on to read more about them:

In the first stage, there is no cognitive decline and the person is mentally sound. There is no memory loss as well.
In the second stage, there is a very mild cognitive decline leading to normal forgetfulness that is often associated with progressing age.
In the third stage, there is a mild cognitive decline. The person has an increased forgetfulness and may find it difficult to concentrate on things.
In the fourth stage, there is moderate cognitive decline and the person starts forgetting even the most recent events. They cannot even travel alone or manage their own finances.
In the fifth stage, there is moderately severe cognitive decline. The person going through this stage often requires help even with their daily activities. People tend to forget even the most common things like phone and email passwords.
In the sixth stage, there is severe cognitive decline. This stage is also called middle dementia and there is prominent memory loss. People cannot even count from 1 to 10. Their speech becomes slurry. They also start having delusions.
In the seventh stage, there is very severe cognitive decline. This stage is also called late dementia. The psychomotor skills are also lost at this stage and the person may not even be able to walk properly.
Some of the early signs of dementia are listed below:

In the initial days of dementia, the person usually tends to get confused when it comes to choosing the right words. This makes them take much longer time to conclude their speech.
There might also be a change in the mood of the person.
Depression is also one of the early signs.

The person will have a tendency to forget even the most recent events that took place in his or her life. This means that they might remember what happened ten years before but they might not remember what they did in the morning.
Early signs also include failure to sense directions. People often tend to forget their addresses and the landmarks and thus become lost when they travel alone.
Confusion is also one of the common signs and this is directly correlated to the loss of memory because when a person cannot remember familiar faces, it leads to a lot of confusion within his own mind.
So, if you suspect that someone in your house is suffering from dementia, then you must look out for these early signs and seek medical help immediately. Early treatment can keep the condition from worsening.

Dementia - Stages and Early Signs!

When particular nerve cells in the brain don't function properly, it leads to epilepsy, which is a common brain disorder. There are several variants of epilepsy, and the one that you are suffering from would play a major role in the type of seizure you are likely to have. Here are the two most common type of seizures:

Common types of Seizures

Generalized seizures: This type of seizures take place when nerve cells on both sides of the brain start misfiring. They may lead to black out, fall or muscle spasms.
Focal seizures: It starts in a particular area of the brain, and the names of the seizure are based on the affected area of the brain. They may lead to both emotional and physical effects which may affect the way a person feels or sees or hear things that have no real presence. In particular cases, the symptoms of focal seizures are regarded of some other kinds of mental or nervous disorder.
Seizures are not considered an either-or thing since some people tend to have a particular type of seizure which gradually alters its course. It is not always easy to classify certain types of seizures which are called unknown-onset seizures and may lead to both physical and sensory symptoms. Both focal and generalized seizures can be categorized into various groups. The most common are listed below:

Subcategories of focal and generalized seizures

Simple focal seizures: It may change how the senses read the surroundings of a person. It can make a familiar taste or smell appear strange. Some people feel dizzy or visualize flashes of light or make the affected individual feel nauseated or sweaty.
Complex focal seizures: It normally happens when a part of the brain which controls emotion and memory gets affected. The affected person may feel awake even when he has lost consciousness. It can take several minutes for a person to come out of the problem.
Secondary generalized seizures: It starts when a part of the brain spreads to the nerve cells. They may lead to a few physical symptoms including muscle slackness and convulsions.
On the other hand, there are six variants of generalized seizures:

Clinic seizure: The muscles tend to have spasms which make a face, neck, and arms jerk rhythmically. It can last for minutes together.
Tonic-clonic seizure: These are the most notable type of seizures and leads to stiffening of the body, jerking and shaking along with the loss of consciousness. It can last between 1 to 3 minutes, and in case they go for a longer span, it is important to seek immediate medical attention. It may lead to breathing issues and may cause the person to bite his tongue or cheek.
Tonic seizures: When the muscled in the legs or arms or trunk tense up for more than 20 seconds, it is called a tonic seizure. If the affected person is in standing position, he or she may end up falling.
Other types of generalized seizure include atonic seizure, absence seizure and myoclonic seizure which are commonly seen in people who have epilepsy.

Seizures - Know The Common Types!

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