Brain cancer is a disease of the brain in which cancer cells (malignant cells) arise in the brain tissue. Cancer cells grow to form a mass of cancer tissue (tumor) that interferes with brain functions such as muscle control, sensation, memory, and other normal body functions. Tumors composed of cancer cells are called malignant tumors, and those composed of mainly non-cancerous cells are called benign tumors. Cancer cells that develop from brain tissue are called primary brain tumors while tumors that spread from other body sites to the brain are termed metastatic or secondary brain tumors.

Prologue:

Brain cancer is actually the abnormal growth and uncontrolled growth of the cancer cells in the brain,that forms a tumor in the brain.Tumours can be either benign or malignant.

Benign brain tumours are abnormal collections of cells that reproduce slowly and usually remain separate from the surrounding normal brain.

Malignant tumours reproduce and grow quickly. Their borders are hard to distinguish from the normal brain around them.

Symptoms:

There are few early symptoms of brain cancer, but as the tumour grows within the confines of the skull, it causes increased intracranial pressure and exerts pressure on the brain, causing signs to develop.

Brain cancer symptoms and signs are varied and depend on the area of the brain involved, but can include:

Headaches.

Seizures.

Nausea and vomiting, which, CANSA reports, may be worse in the morning or after a sudden position change.

Difficulty walking or clumsiness.

Vision changes.

Changes in alertness.

Behavioural impairment.

Causes:

Brain cancer occurs when there is an uncontrolled growth of cancer cells in the brain that form a malignant brain tumor. The underlying cause of primary brain cancer, cancer that begins in the brain, is not known. Secondary brain cancer is caused by a cancer of another organ in the body, such as the breast, prostate, kidney, skin, or bone, that has spread to the brain.

What are the risk factors for brain cancer?

Certain inherited conditions, including neurofibromatosis, Von Hippel-Lindau syndrome, Li-Fraumeni syndrome, and Turcot syndrome

Personal history of cancer or family history of brain cancer

Impaired immune system

Radiation therapy of the head

Treatments Options:

Treatment

Surgery is the main form of treatment for brain tumors that lie within the membranes covering the brain or in parts of the brain that can be removed without damaging critical neurological functions. The goal is to remove the entire tumor, whenever possible, as a tumor may recur if any tumor cells are left behind. Radiation therapy and chemotherapy are generally used as secondary treatment for tumors that cannot be cured through surgery alone.

Stereotactic radiosurgery

Stereotactic radiosurgery is a treatment option that delivers a high concentration of radiation directly to the tumor in order to stop its growth, while delivering only a minimal dose of radiation to the surrounding tissue. Unlike conventional surgery, stereotactic radiosurgery does not require making an incision to remove the tumor. It can be especially effective in patients with many small metastatic brain tumors.

Brain Cancer

Obesity is the new-age lifestyle disease with multiple ramifications. While its effects on the physical aspects are very evident, the damage it does to the brain are more severe, though not obvious. Read on to know some harmful effects of obesity on the emotional well-being.

Leads to binge eating: There is a certain pleasure in eating sugary and fatty food, and this is lost with depression. Therefore, to get that emotional satisfaction, people tend to eat more chocolates, cookies, milkshakes, and other weight-accumulating food items, which further add to obesity. Greater the weight gained by a person, lesser the response or happiness from such food products.
Increases impulsivity: The area of the brain known as orbitofrontal cortex, which is in charge of controlling impulsivity, shrinks in obese people. This results in people eating more impulsively.
Affects immunity: Obesity is a major cause of inflammation, leading to damage in certain parts of the brain. This impairs the immune system, making the affected person more prone to infections and tissue damage. This leads to increased chances of diabetes, heart disease, stroke, sleeping disorders, eating disorders, etc. The chemical known as C-reactive protein increases as seen on MRIs in obese people, and which is usually seen in patients with chronically increased inflammation.
Effects on memory: As the BMI increases, there is a decrease in scores of memory tests. This effect is more obvious in women after menopause. With increased fat accumulation, more hormones are released, which affects the memory. Increased inflammation also affects cognition and memory.
Increased risk of dementia: With more belly fat accumulating, there is extra stress on the body to burn the visceral fat. This reduces brain size and causes certain hormones to release, which further affects the body s ability to remember things. It has been proven that people with smaller brain size are at greater risk for developing dementia.
Weight loss stress adding to more stress: When obesity sets in and the BMI goes up, there is an added pressure to lose weight, which further ups the stress levels. During these dieting days, the brain is constantly alert and finds ways to eat more. This also leads to excess eating. Moreover, there are indications that there could be genetic changes during this phase, which may leave a permanent mark in the person s composition.
Depression: When a person is not happy with their reflection in the mirror, the chances of feeling good and happy are very less. In this age, where aesthetics plays a major morale booster, an obese image staring back does not help at all.
So, if you have a risk of obesity, watch out. It is not just how you look, but how you feel is also altered.

Obesity - How It Affects The Human Brain?

Snoring is something that not only spoils the sleep of your partner but leaves you embarrassed while travelling or any family gatherings. It is more popular among males but these days, women are also facing this issue. The problem only worsens with age and weight. On the other hand, the person suffering from Sleep Apnoea not only affects his and his partner's sleep but puts his life at risk.

Difference Between Sleep Apnoea And Snoring:

There is a huge difference between just Snorers and those suffering from Sleep Apnoea. Sleep Apnoea almost always results in frequent and loud snoring, while disturbing the breathing pattern. This leads the person suffering from Sleep Apnoea to feel tired even after long sleeping hours.

While Sleep Apnoea will almost always lead to loud snoring, snoring alone does not mean that one is suffering from Sleep Apnoea.



Causes And Symptoms

Snoring

  When a person sleeps, the throat muscles relax and the tongue bends backwards. This narrows down the throat to some extent.
  As the person keeps inhaling and exhaling, the throat muscles vibrate. These vibrations lead to snoring. The narrower the throat becomes, the more are the vibrations and the sound.
  The throat muscles tend to relax more with age. This is why snoring usually increases with age.
  If a person has obstructions in the form of Tonsils, Nasal polyps or Deviated nasal septum, the narrowing gets worse and leads to extensive snoring.
  If there is an inflammation in the throat or nose due to some infection or allergy, the throat may become narrower and result in loud snoring.
  In some people, sleeping positions like sleeping on the back or otherwise may abate snoring.
  Alcohol consumption during evening time may abate throat muscle relaxation and give rise to snoring.

Sleep Apnoea

  It is better described as episodes of pauses in breathing for more than 10 seconds at a time.
  The immediate cause of Sleep Apnoea is extensive narrowing or complete collapse of the upper airway.
  As breathing is paused temporarily, it causes a shortfall of Oxygen in blood. As it happens, the heart works harder to make up for it, even when the person is sleeping. This increases the risk of heart attack and stroke.
  It causes disturbance in the natural sleep cycle.

Treatment

Snoring

  Avoidance of risk factors like various allergies
  Correction of sleeping position with training

Sleep Apnoea

  The most common treatment is CPAP (Continuous Positive Airway Pressure). This is a mask like device worn on the nose before sleep. It keeps the upper airway open with a small positive pressure delivered.
  There is also the option of Uvulopalatopharyngoplasty. This is a surgical intervention to remove excess of soft palate tissue and open up the airway. The remaining tissue becomes stiff and thus minimize vibration.
  If there is a Tonsil or Deviated Nasal Septum or Nasal Polyp, it needs to be resected out in order to minimize obstruction to the airway.

Snoring and Sleep Apnoea are very common issues and can be treated by experienced doctors very easily.

Ways to diagnose snoring and sleep apnoea:

The doctors ask about the allergies you are suffering from, as well as your eating patterns, medicines and drinking and smoking habits. The doctor also examines your throat and nasal passages to ascertain if there are any kind of nasal, dental, mouth jaw, or throat deformities that are triggering your snoring. If your doctor will feel that you may be suffering from sleep apnoea, then your partner may be asked to keep a diary noting your sleeping and snoring patterns.

Polysomnography and CPAP Titration are some other ways through which the doctors diagnose sleep apnoea.

Polysomnography: Polysomnography, also called a sleep study, is a type of test that is conducted to diagnose sleep disorders. In this test, the doctors record the brain waves, the oxygen level in the blood, heart rate and breathing, as well as eye and leg movements of the patient.

CPAP Titration: A CPAP titration study is a type of in-lab sleep study that is carried out to calibrate continuous positive airway pressure (CPAP) therapy. It is a common treatment that is used to manage sleep-related breathing disorders including obstructive sleep apnea, central sleep apnea and hypoventilation and hypoxemia.

In case you find out that you are suffering from snoring or sleep apnoea, you should immediately visit a pulmonologist to get the proper treatment. 

Snoring And Sleep Apnoea - How To Get Rid Of Them?

Epilepsy is one of the most common neurological disorders. This condition can affect men and women of all ages. However, it is associated with a number of myths. As a result of these myths, epileptic patients are often discriminated against. Let s bust a few of these myths.

Myth 1: Epilepsy is contagious
Coming in contact with an epileptic patient will not increase your risk of suffering from this condition. Epilepsy can be caused by a number of factors but is not transferable from one person to another. Factors triggering epilepsy include genetic defects, oxygen deprivation at birth, trauma to the head and strokes.

Myth 2: Epilepsy cannot be treated
There is no known cure for epilepsy but this condition can be managed with treatment. Treatment for epilepsy can take many forms. The most common amongst these is medication to reduce and stop seizures. In some cases, brain surgery may also be advised. A special diet can also help control epileptic attacks. Lastly, nerve stimulation may also be used to treat epilepsy.

Myth 3: Epileptic patients cannot lead a normal life
There is nothing stopping an epileptic patient from living a normal life like everyone else. Epilepsy does not affect a person s intelligence or any other ability. It is also a misconception that epileptic women cannot have children or that their children will also have epilepsy. With treatment and a healthy prenatal plan, they can have a healthy pregnancy and give birth to a healthy child. However, certain activities like driving should be avoided by epileptic patients.

Myth 4: A person having an epileptic fit should be restrained
An epileptic seizure will run its course and restraining the person may do more harm than good. Instead, the person should be made to lie down on their side. This will keep saliva from collecting in their mouth. Clear the area around the person and loosen their clothing. If the person wears spectacles, these should be removed. Do not try and put anything into the person s mouth. An epileptic fit usually lasts for up to 5 minutes. If the person does not recover within that time, call a doctor immediately.

Myth 5: Anyone who has a seizure is epileptic
Seizures are not synonymous with epilepsy. They can be triggered by a number of factors including excessive drinking, heat, injury to the head etc. To be diagnosed with epilepsy, a person should have had two or more seizures with unrelated triggers. 

Myths About Seizures - Debunked!

Hypopituitarism is defined as a condition in which the pituitary gland is unable to produce enough hormones. Under-secretion of pituitary hormones affects reproduction, body growth and blood pressure. It also results in pre-mature aging.

The pituitary gland is a small bean-shaped gland situated at the base of your brain, behind your nose and between your ears. Despite its size, this gland secretes hormones that influence nearly every part of your body.

In hypopituitarism, you have a short supply of one or more of these pituitary hormones. This deficiency can affect any number of your body's routine functions, such as growth, blood pressure and reproduction.

Few Causes:

Head injury

Tuberculosis

Radiation treatment

Stroke

Brain tumors

Brain surgery

Meningitis (brain infection)

Hypophysitis (autoimmune inflammatory disorder)

Sarcoidosis is an infiltrative (accumulation of cells and tissues in excess of the normal amount) disease which occurs in various organs.

Impaired hormone secretion by the pituitary gland is caused by genetic mutations.

Sheehan s syndrome: It is a condition in which the pituitary gland gets damaged due to severe blood loss during childbirth.

Hypothalamus (a part of the brain which is located above the pituitary gland) diseases wherein the pituitary activities are directly affected by the hypothalamus.

Symptoms:

Fatigue

Reduced sex drive

Decreased appetite

Anemia

Irregular menstruation, pubic hair loss, hot flashes (feverish heat), and inability to breast-feed properly because of low breast milk production).

Dwarfism in children

Weight loss

Increased sensitivity to cold temperature

Infertility

Facial puffiness

Reduction in body hair or facial hair

Treatment Options:

Hormone replacement drugs include:

Corticosteroids: Adrenocorticotropic hormone deficiency leads to low production of adrenal hormones (different kinds of hormones such as cortisol and adrenalin, produced in the endocrine glands). These drugs act as a replacement of adrenal hormones.

Growth hormone: Growth hormone, also known as somatropin, is injected beneath the skin. This treatment method promotes growth, which balances the height in children. Growth hormone deficiency in adults is also cured by these medications to some extent.

Surgery: Surgical procedure is needed if the condition of hypopituitarism is the result of a tumor. The doctor will remove the tumor through surgery, thus resulting in normal growth.

Radiation: Radiation therapy helps in reducing the size of the tumor which causes stunted growth or pre-mature aging.

Hypopituitarism: Causes, Symptoms and Treatment

Pain related sleep disruption has affected a large number of people around the globe. Statistics has it that, in India, about 25% of the population suffers from pain-related sleep deprivation. Studies call it  the vicious cycle of pain and sleep  as pain affects your ability to sleep and lack of sleep makes the pain even worse.

Back pain and arthritis are examples of some common pain-related medical disorders. People with these types of chronic pains have reported persistent sleeplessness or have had immense trouble falling asleep.

The following are the primary sleep disorders associated with chronic pain:

Insomnia: It is a medical condition that is characterized by an inability to fall asleep no matter how physically exhausted you are. Insomnia can be acute (lasting for one night to a week) or chronic (that lasts for more than 3 weeks).
Hypersomnia: It is a condition wherein you tend to sleep excessively; in this condition, you will have trouble being awake throughout the day or can fall asleep at any point of time.
Sleep Apnoea: This is a sleep disorder wherein breathing pauses and resumes repeatedly. Risk factors include obesity, age and gender; it is more commonly observed in men. This condition can be chronic with symptoms such as snoring loudly or feeling very tired even after one has had a night s sleep.
Restless leg syndrome: It is a sleep disorder wherein you continuously move your legs while sleeping. However, this condition can also cause you to move your legs even if you aren t sleeping.
Some of the causes of sleep disorders due to chronic pain are:

Pain
Worry and anxiety
Sweating at night
Depression and other mental disorders
Treatment

A pain and sleep disorder should be simultaneous as both the components of it, pain and sleep, are interrelated. Some of the ways people with chronic pain can still have a good night s sleep are:

Limiting caffeine intake
Abstaining from alcohol and smoking, as these disrupt the sleep cycles, thus aggravating the existing pain.
Practicing meditation and other relaxation techniques
Pain killers or sleeping pills can be administered, but only with the doctor s advice.
Hot water fomentation over painful area during night, for better sleep.

Back Pain and Bad Sleep

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