Female infertility is considered as the inability of conceiving. As per WHO it is described as the inability to be pregnant, maintain and carry forward a pregnancy to its full term. It is often of two types:

    Primary Infertility: This is the inability to give birth to a baby either due to the inability to become pregnant or maintain a pregnancy, which includes stillborn and miscarriage.
    Secondary Infertility: This refers to the inability to give birth when there is already a live birth or the woman was pregnant.

The causes of infertility can vary from being acquired or genetic. However, following factors are largely responsible for infertility:

    Genetic: Some genes can lead to mutation leading to infertility like, in case of BMP15 gene there is a hypergonadotrophic ovarian failure which causes infertility.
    Acquired: This is caused by factors like age, smoking, sexually transmitted diseases, obesity, body weight, eating disorders, diseases like diabetes, thrombophilia and also radiation and chemotherapy.

The treatment for infertility usually depends on the cause, age, duration of time for which a person has been infertile and preference of the patient. Infertility is believed to be a complex disorder and the treatment involves a huge amount of physical, financial and psychological commitments. All this also requires a lot of time. Some women might need just a minimum of two therapies to attain fertility while others might require different treatment before they can conceive.

Treatment is largely aimed to restore the fertility either by means of medication and surgery or help in reproduction with the help of some procedures.

Fertility Restoration through medication

This is the main treatment for women who are infertile because of ovulation disorders. These drugs include:

    Gonadotropins: These are injected to stimulate the ovaries. Drugs like Menopur, Repronex, Follistim AQ, Gonal-F, Bravelle restore the production of eggs, while Ovidrel and Pregnyl are used for maturing the eggs and for their release.
    Clomiphene citrate: This is taken orally and stimulates ovulation by releasing more Follicle Stimulating Hormone and Luteinizing Hormone from the pituitary gland.
    Metformin: This is used in females who have PCOS and also when insulin resistance plays a major role in infertility.
    Bromocriptine: Used when the infertility is caused due to excess prolactin production.
    Letrozole: This also induces ovulation

Fertility Restoration through surgery

Surgical procedures can amend the problem of infertility. However, these treatments are very rare these days owing to the success of other fertility treatments. These include:

    Tubal ligation reversal surgery: In case a tubal ligation has been performed it can be reversed by reconnecting the tubes again through surgery.
    Hysteroscopic surgery: This corrects or removes the abnormalities that cause infertility. This surgery can correct the shape of the uterus, remove endometrial polyps and improve chance of getting pregnant.
    Tubal surgeries: In case of blocked fallopian tubes laproscopic surgery can be performed to dilate the tubes, removed blockages or create a new opening.

Assistance in Reproduction through techniques

The most common used techniques for reproduction assistance are:

    Intrauterine insemination or IUI: In this about million healthy sperms are put in the uterus at the time of ovulation.
    Assisted reproductive technology: In this mature eggs are retrieved from a woman and this is then fertilized with sperms in a dish in the lab. Once the fertilization is done the embryo is placed in the uterus for further development. IVF is the most common and effective assisted reproductive technology. This procedure takes place over weeks with several blood tests and hormone injections.

Dealing with infertility is not easy and can be emotionally and physically draining. To cope with the various tests and treatments of infertility one should be fully prepared, eat a healthy diet, exercise reach out for help and support of family and friends and look for other options like a donor egg, adoption or no children.

Treatments of Infertility

Individuals who stood for an extra two hours daily had about 2% lower blood glucose levels and 11% lower average triglycerides, compared to those who spent more time sitting. More time spent standing rather than sitting could improve your blood sugar, fats in the blood and cholesterol levels, while replacing time spent sitting with time walking could have additional benefits for your waistline and body mass index.




Wellness in Diabetes - Avoid Sitting Too Long To Stay Healthy

Insulin is the most common treatment prescribed for people affected with diabetes. Diabetes is condition where high amounts of glucose prevail in the blood for an extended period of time. However, there are some drugs that offer an alternative to insulin in treating diabetes, which are:

1. Liraglutide: Liraglutide is a glucagon-like peptide-1 (GLP-1) drug that causes the body to release greater amounts of insulin so as to facilitate the movement of glucose from the blood to the cells. People with type 2 diabetes generally use this treatment. It slows the digestion process and can cause symptoms of headache and nausea. 

2. Pramlintide: It's an artificially produced version of amylin. It is taken by both type 1 and type 2 diabetic patients, facilitates slower digestion of food and therefore, controls release of sugar in the blood. It can cause tiredness and nausea.

3. Dulaglutide:This treatment is for people affected with type 2 diabetes and it is administered once a week. It causes more insulin to be released and pass the glucose to the cells. It can cause loss of appetite, nausea and abdominal cramps as side effects.

4. Albiglutide: This treatment facilitates pancreas to release insulin and limits the glucagon hormone production. It is used by type 2 diabetes patients who have not taken well to other treatments. The side effects are skin reaction, respiratory tract infection and nausea.

5. Exenatide: It is a drug that causes pancreas to release insulin that facilitates movement of glucose to cells. It is a treatment for type 2 diabetes and it restricts release of glucagon in the body. The possible side effects are acidity, constipation and vomiting.

Common Insulin Alternatives

Can Exercise Help Control Blood Sugar Levels?

It is an established fact that regular physical exercise has wonderful effects on the overall health of a person. People of all ages can reap the benefits of exercise that take manifestation in all the various systems of the human body.

One such healthy effect of exercise is that it can help control blood sugar levels. For those who have been diagnosed with diabetes, exercise works like any other drug in keeping blood glucose at an optimal level. It also helps in preventing further health complications that may be caused by this condition, such as heart disease or strokes.

How does exercise control blood sugar?

Exercise affects the body's blood glucose levels in the following ways:

- Exercising increases insulin sensitivity, which makes the body more capable of using insulin to take up available excess glucose in the bloodstream.

- Muscle contractions during exercise stimulate the cells to use up glucose to produce energy.

- Heightened cardiovascular activity while exercising burns through blood glucose a lot faster.

It is necessary to keep checking blood sugar levels at regular intervals, especially if you suffer from diabetes. Working out has different effects on different individuals, depending on the duration and intensity of exercise and the overall health and medical history of the person.

What are the best ways to use exercise to reduce blood sugar levels?

It is important to chalk out a suitable exercise routine that is tailored specifically to your individual needs. Consult a health care specialist or physical therapist for formulating the best possible workout regime for your specific requirements.

Most experts recommend engaging in moderately intense exercise for a minimum of 150 minutes in a week.

A few examples of activities that fall under this category are as follows:

-Brisk walking
-Cycling
-Swimming
-Squats and lunges
-Stretching exercises
-Yoga

One thing that diabetes patients should always keep in mind is that over-exercising must be avoided. Excessively strenuous workouts can lead to hypoglycemia (deficiency of blood glucose) which is a highly unsavory condition.



Can Exercise Help Control Blood Sugar Levels?

Women tend to develop high levels of blood sugar during their pregnancy (especially within the 24th and 28th weeks), irrespective of whether they already had suffered from diabetes prior to their pregnancy. However, gestational diabetes, if not taken proper care of, might escalate the risks of developing diabetes in the near future for both the mother and the child, accompanied by complications in pregnancy or labor. Gestational diabetes is usually characterized by mild symptoms such as excessive urge to urinate, excessive thirst, blurred vision and fatigue.

Causes:
Insulin, a hormone produced by the pancreas, allows for the utilization of the glucose for energy. The food consumed is broken down by the digestive tract of the body, converting carbohydrates into glucose before releasing it into the bloodstream. The glucose is then absorbed by the cells to be used as an energy source. Now, at the time of pregnancy, the placenta (organ nourishing the fetus) connecting the baby to the blood supply also produces various other hormones in high levels, for instance, estrogen and human placental lactogen. Most of these hinder the normal functioning of insulin in the cells, hence raising the blood sugar count. With subsequent growth of the baby, the placenta keeps on producing more amounts of such insulin resistant hormones to an extent that they are capable of meddling with the development of the baby.

Treatment:
1. Monitoring the blood sugar count at least four to five times a day and keeping it under control might help to ease the complication.
2. A healthy diet consisting of whole grains, vegetables and fruits in the right proportion and limiting sugar or other highly refined carbs meets the nutrition and fiber requirement of the body. Guard against additional weight gain during pregnancy as that hampers the entire process.
3. Exercise or regular physical activities help to normalize blood sugar level by boosting glucose absorption in the cells. Furthermore, exercises also enhance the sensitivity of the cells towards insulin. This means that only a little amount of insulin production by your body would be enough for the transportation of sugar.
4. Medication, If exercise and diet fall inadequate, insulin injections are often administered to control blood sugar count.
5. Keeping the baby under close observation with the help of repeated ultrasound and other tests to record its growth and development is an essential part of the treatment plan.

Gestational Diabetes - How It Can Be Treated?

 Thyroid is a small gland situated in front of the neck and secretes hormones like thyroxine (T4) and tri-iodothyronine (T3). These hormones control various functions of our body like heart, blood pressure, digestion, metabolism, growth, blood formation, brain function etc. Any fluctuation in the functioning of the thyroid gland can have a great impact on health. The thyroid gland is primarily responsible for energy and metabolism. This gland triggers the genes that make all the cells in the body conduct their specific jobs. But over a period of time, the optimum functioning of the thyroid may reduce because of specific reasons. The gland may start to under-produce or overproduce the thyroid hormone, which may lead to conditions known as hypothyroidism or hyperthyroidism, respectively. 

Patients with hypothyroidism may feel extreme tiredness and fatigue even though they may be sleeping more than before. An unexplained gain in weight, constipation, inability to stand cold temperatures, and constant pain in muscles and joints are some of the other symptoms of hypothyroidism. 
Hyperthyroidism, or overactive thyroid, is an endocrine disorder. Patients with this disorder may experience excessive sweating, fatigue, and intolerance to heat. They may even experience restlessness, puffy or protruded eyes, hair loss, and muscle weakness. Such patients may lose weight and are unable to sleep properly at night. In some cases, palpitations or abnormal heart rhythm may also be experienced. 
Complications of Thyroid Disorder 

Hypothyroid and hyperthyroid can cause a number of complications if patients don t take medications. It is important for you to not to ignore any of the aforementioned symptoms and speak to your doctor as soon as possible. 

Hypothyroid complications

Myxedema: This condition is characterized by slowed thinking, swelling of tissues, and accumulation of fluid around major organs like brain, lungs and/or heart. This condition may prove life-threatening if not treated on time. 
Enlarged goiter: This is characterized by enlargement of the thyroid gland because of a constant increase in the TSH levels. High cholesterol and triglycerides: This may eventually pave way for heart disease and stroke. 
Sleep apnea: Sleep apnea is a disorder that affects nighttime breathing where the brain that temporarily stops sending signals to the muscles that control breathing, or by an obstruction in the airway. This may prove fatal if left untreated. 
Low blood pressure: This means not enough blood is getting to capillaries and tissues, particularly in your hands, feet, and brain. You may have chronic nail fungal infections and cold hands and feet if so. 
Hyperthyroid complications 

Heart disorders (cardiac arrest): If left untreated, excess thyroid hormones can lead to congestive heart failure and heart rhythm disorders. 
Osteoporosis: Too much thyroid hormones interfere with the body s ability to use calcium to build bone. This may lead to brittle bones and osteoporosis. 
Thyrotoxic crisis: This is a rare yet life-threatening complication characterized by high fever, vomiting, irregular heartbeat, and agitation. 
Hypertension or high blood pressure: It is a condition in which a patient has high blood force striking the walls of the artery An early diagnosis can help make the treatment of this disorder easier. 
Depending on the condition of the thyroid condition, it requires different ways to manage it. The conventional TSH (thyroid-stimulating hormone) and T-4 (thyroxine) blood tests will be advised and the results should provide a reasonable confirmation of the condition. If doubts still persist an ultrasound or scan can also be ordered. In case you have a concern or query you can always consult an expert & get answers to your questions!

Is Your Thyroid Gland Working Against Your Body? 

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