Addison s disease is known as adrenal insufficiency or hypocortisolism. It is a hormonal disorder which occurs when adrenal glands which are located just above the kidneys do not produce enough of the hormone. The hormones produced by adrenal glands include cortisol and aldosterone, which are essential for a healthy life.

The disease is characterized by weight loss, muscle weakness, fatigue, low blood pressure, and darkening of the skin also sometimes. Most cases of Addison's disease are caused by autoimmune disorders.
It is quite a rare condition. Only 1 in 1 lakh suffer from this condition. this condition can affect a person of any age group irrespective of sex. To live a normal life people, with this condition, a patient will be required to take their medication regularly.

Cortisol and Aldosterone - What do they do?
The most important function of the cortisol in the body is to respond to stress. It helps the body in using protein, carbohydrates, and fat. It maintains blood pressure, cardiovascular function; and controls inflammation. While as aldosterone helps kidneys in regulating the amount of salt and water in the body   which helps in regulating blood volume and keeping blood pressure under control.

Cause of Addison's Disease
Mostly Addison s disease occurs due to problems with adrenal glands themselves   which is known as primary adrenal insufficiency. While Autoimmune disease accounts for 70% of Addison s disease. In this condition, the body's immune system mistakenly attacks the adrenal glands. This attack destroys the outer layer of the glands.

Some long-term infections such as tuberculosis, HIV, and some fungal infections harm the adrenal glands. It is also caused by the cancer cells that spread from other parts of the body to the adrenal glands.
Less commonly, adrenal glands can also be affected by secondary adrenal insufficiency. It is caused by a problem with the pituitary gland or a problem with the hypothalamus, both located in the center of the brain.
These glands produce hormones that control the production of hormones in the rest of the body. A pituitary hormone called ACTH which turns on cortisol production in the adrenal gland. If ACTH levels are too low, the adrenal glands do not function.
One more cause of secondary adrenal insufficiency is also caused by the prolonged or abuse of steroid hormones such as prednisone.
Symptoms of Addison's disease
The symptoms of adrenal insufficiency grow gradually and the main characteristics are:

Chronic, worsening fatigue
Muscle weakness
Loss of appetite
Weight loss
About 50 percent of the time, one will notice:

Nausea
Vomiting
Diarrhea

A Quick Guide To Addison's Disease!

 Thyroid is a small gland situated in front of the neck and secretes hormones like thyroxine (T4) and tri-iodothyronine (T3). These hormones control various functions of our body like heart, blood pressure, digestion, metabolism, growth, blood formation, brain function etc. Any fluctuation in the functioning of the thyroid gland can have a great impact on health. The thyroid gland is primarily responsible for energy and metabolism. This gland triggers the genes that make all the cells in the body conduct their specific jobs. But over a period of time, the optimum functioning of the thyroid may reduce because of specific reasons. The gland may start to under-produce or overproduce the thyroid hormone, which may lead to conditions known as hypothyroidism or hyperthyroidism, respectively. 

Patients with hypothyroidism may feel extreme tiredness and fatigue even though they may be sleeping more than before. An unexplained gain in weight, constipation, inability to stand cold temperatures, and constant pain in muscles and joints are some of the other symptoms of hypothyroidism. 
Hyperthyroidism, or overactive thyroid, is an endocrine disorder. Patients with this disorder may experience excessive sweating, fatigue, and intolerance to heat. They may even experience restlessness, puffy or protruded eyes, hair loss, and muscle weakness. Such patients may lose weight and are unable to sleep properly at night. In some cases, palpitations or abnormal heart rhythm may also be experienced. 
Complications of Thyroid Disorder 

Hypothyroid and hyperthyroid can cause a number of complications if patients don t take medications. It is important for you to not to ignore any of the aforementioned symptoms and speak to your doctor as soon as possible. 

Hypothyroid complications

Myxedema: This condition is characterized by slowed thinking, swelling of tissues, and accumulation of fluid around major organs like brain, lungs and/or heart. This condition may prove life-threatening if not treated on time. 
Enlarged goiter: This is characterized by enlargement of the thyroid gland because of a constant increase in the TSH levels. High cholesterol and triglycerides: This may eventually pave way for heart disease and stroke. 
Sleep apnea: Sleep apnea is a disorder that affects nighttime breathing where the brain that temporarily stops sending signals to the muscles that control breathing, or by an obstruction in the airway. This may prove fatal if left untreated. 
Low blood pressure: This means not enough blood is getting to capillaries and tissues, particularly in your hands, feet, and brain. You may have chronic nail fungal infections and cold hands and feet if so. 
Hyperthyroid complications 

Heart disorders (cardiac arrest): If left untreated, excess thyroid hormones can lead to congestive heart failure and heart rhythm disorders. 
Osteoporosis: Too much thyroid hormones interfere with the body s ability to use calcium to build bone. This may lead to brittle bones and osteoporosis. 
Thyrotoxic crisis: This is a rare yet life-threatening complication characterized by high fever, vomiting, irregular heartbeat, and agitation. 
Hypertension or high blood pressure: It is a condition in which a patient has high blood force striking the walls of the artery An early diagnosis can help make the treatment of this disorder easier. 
Depending on the condition of the thyroid condition, it requires different ways to manage it. The conventional TSH (thyroid-stimulating hormone) and T-4 (thyroxine) blood tests will be advised and the results should provide a reasonable confirmation of the condition. If doubts still persist an ultrasound or scan can also be ordered. In case you have a concern or query you can always consult an expert & get answers to your questions!

Is Your Thyroid Gland Working Against Your Body? 

One of the most important decisions a couple takes is to start a family. It fills them with hope and joy of new future, but if the attempts have been unsuccessful for more than six months, it can take a toll on the relationship and the mental health of the couple. This is the time to seek fertility specialist who will be appropriate to analyze the situation and provide proper guidance. Read on to find out the exact indications to see a fertility specialist:

1. If a woman who is under the age of 35 is unable to get pregnant even after a year of having regular unprotected sex
2. A woman who has had more than three miscarriages
3. Someone who has suffered from blocked fallopian tubes and is in need of surgery
4. One who experiences irregular ovulation
5. A couple who has suffered from genital infections
6. A pregnant woman who has consumed an estrogen derivative
7. A man who has been diagnosed with low semen count, also known as poor motility
8. A couple who has not been diagnosed with any irregularity but is infertile

Which specialist should you visit?

If you or your partner or both have shown signs of infertility, then visiting the following specialists can be helpful:

Specialists for men

Urologists and Andrologists are specialists who treat men for infertility. Urologists conduct an analysis of semen quality, semen count, hormone levels, reproductive organs and abnormalities in bladder and kidneys. Andrologists are medical professionals who specialize in hormonal conditions and physiology of male infertility.

Specialists for women

Hormonal imbalance is one of the potent obstacles to pregnancy. If a general obstetrician/gynecologist has not been able to successfully treat a woman then she can visit a reproductive endocrinologist who specializes in hormonal disorders. Depending upon the nature of the problem, she can also visit a reproductive surgeon who deals with uterine abnormalities, endometriosis, and reproductive organ surgery.

When Should a Couple See a Fertility Specialist?

Gestational diabetes, as the name suggests, occurs during gestation or pregnancy when the blood sugar levels exceed the normal level. Gestational diabetes, like other form of diabetes, affects how your body cells use glucose or sugar during pregnancy, and usually disappears after you ve given birth.

Causes and symptoms to look out for!
During gestation, the placenta produces hormones that lead to the accumulation of blood glucose. Under normal condition, the pancreas forms enough insulin to counter the buildup of blood glucose. The level of blood sugar rises when the pancreas fails to produce adequate insulin to manage your blood sugar.

Usually, women with gestational diabetes do not show symptoms. So, the presence of the condition can go unnoticed if they are not diagnosed during routine checkups and screening tests. Nevertheless, if the condition goes out of control, you may feel tired, feel thirsty or hungry, or feel the urge to urinate more often.

What are the risk factors?
About 2-10% of pregnant women are affected by gestational diabetes every year. The following factors are likely to put you at risk of developing gestational diabetes-

Excess body weight- You may develop gestational diabetes if you were overweight or had gained excess weight (BMI equal to or greater than 30) before getting pregnant
Family history- Women who have a family history of diabetes are likely to have gestational diabetes.
Age- Women aged more than 25 years are at a greater risk of developing this condition.
Diabetic history- A slightly raised blood sugar level may act as the precursor to Type-2 diabetes, which in turn increases your chance of getting affected by gestational diabetes.
Previous pregnancy- Women who ve previously given birth to a child weighing more than 4.1 Kg (9 pounds), or have delivered a stillborn child are likely to have gestational diabetes.
What is the treatment for gestational diabetes?
Urine tests are performed to check for ketones. In a non-diabetic person, glucagon, insulin and other hormones avert ketone levels in your blood from soaring up too high. Once you re diagnosed with gestational diabetes, it s important that you consult your doctor for treatment. Uncontrolled blood sugar level can affect you and your baby s health after birth. This condition can be treated in the following ways-

Keep a check on your blood sugar- During pregnancy, your doctor will have you tested for gestational diabetes 4-5times a day to keep a tab on your blood glucose level. For this, a small drop of blood is first drawn from the finger using a needle. The sample of blood is then placed on the test strip inserted into a device called the blood glucose meter to measure and monitor the level of blood sugar in your body.
Medication- Anti-diabetic medications and insulin are prescribed to control the amount of glucose or sugar in the bloodstream. Your doctor may also suggest oral medications like Diabeta and Glynase to manage your blood glucose level.
Healthy diet- Diabetic diet- one that helps control blood sugar levels- is highly prescribed by doctors during pregnancy. Cut down on carbohydrates and sugar, and switch to food items that provide your body sufficient nutrients and calories.
Post treatment the blood sugar levels usually come down to normal within 4-6 weeks of giving birth.

Gestational Diabetes - Know The Risk Factors!

The thyroid gland in your body is responsible for controlling and secreting those hormones that help in your natural growth and development. These hormones are crucial in regulating some of the most important functions of your body,  such as your heart rate, breathing, your body weight, your menstrual cycle and your muscle power to name a few. 

Problems of the thyroid gland (such as hypothyroidism or hyperthyroidism) can hamper all of these vital functions, and these problems usually arise due to a poor diet. However, your diet can also help in improving the health of your thyroid gland. Here are some diet tips to help you out:

1. Include lots of iodine in your diet
Iodine is a  nutritive element, without which your thyroid gland will not be able to function at all, being its building block. Therefore, iodine rich foods, such as fortified salt, eggs, seaweed and other dairy products should be a part of your diet. Along with iodine, zinc, selenium, copper and iron are other very important elements that should be a part of your diet too. 

2. Plenty of B vitamins and antioxidants help
Since stress (blame it on cortisol, the stress hormone that overworks your thyroid in case of chronic stress) plays a major role in hampering the proper functioning of your thyroid gland, eliminating it and detoxifying yourself is extremely important. This can be done by  including plenty of B vitamins and antioxidants in your diet. White meat, fishes like tuna, peanuts, brown rice and fruits such as goji berries and wild blueberries can be of great help in this regard.

3.  Say no to soy
Soy is one of the main culprits behind the malfunctioning of your thyroid gland, as it contains an element known as isoflavones, which can reduce the iodine reserve in the gland. Apart from that, vegetables that belong to the brassica family such as cauliflower, cabbage and Brussels sprouts are linked to causing goitre and must be avoided. Consumption of gluten must be avoided too, as it can cause autoimmune thyroid disorders, celiac disease and hormonal imbalances.

4. Enjoy your daily meals
In today's fast paced world a stress-free meal is a thing of the past as most people are in a rush to get done with their breakfast, lunch or dinner. This hampers your digestive function and also puts stress on your thyroid glands. The best way to eat is to sit on a table and relax, enjoying every morsel you swallow. This ensures your thyroid remains healthy.

Diet Tips to Improve the Health of Your Thyroid Gland

Both women and men suffer from infertility troubles. There are a host of causes that may lead to infertility in men such as lifestyle choices and obesity. Male infertility is characterized by irregular sperm function or reduced sperm count. Infertility has emerged as a common problem as a result of the modern day lifestyle. Extremely hectic schedules, stress, burnout, depression, unhealthy diets; all of these can contribute to fertility issues.

The various reasons for infertility in men are:
1. If you are overweight, then it is time to lose those extra kilos. Obesity leads to a number of health problems, one of them being erectile dysfunction.
2. Various hormonal problems such as complications of the hypothalamus, pituitary and adrenal glands may lead to low testosterone levels in the body.
3. Various infections such as inflammation of the testicles and epididymis that causes blockage of the tubes carrying the sperm can be a cause.
4. Various medications such as using anabolic steroids, antifungal medications and chemotherapy may hamper production of the sperm and thus hit fertility.
5. Both alcohol and cigarettes may cause problems in sperm production, and cause erectile dysfunction. Excessive drinking may lead to complications in the liver resulting in infertility.

The reasons of infertility may range from medical causes to lifestyle choices; some of the causes may be related to the environment. A common cause of infertility is due to problems with transportation of the sperm. These are mainly due to blockages in the tubes that carry the sperm.

Symptoms of infertility in men are:
1. You may experience low libido
2. Your sperm count may be low
3. You may experience lumps or swellings in the testicles
4. Chromosomal complications such as reduced body hair
5. You may have chronic respiratory problems.

What Causes Infertility in Men?

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