Abstract

Background: it is essential to have an understanding of life expectancy and risk factors among patients with sickle cell disease (sickle cell anemia, hemoglobin diseases, and thalassemias). These are required to counsel the patients, target treatment, and plan the right clinical trials.

 

Methods: a research followed 3764 people ranging from birth to 66 years of age and suffering from scd. The procedure was done to understand the life expectancy and calculate the average age at death. Moreover, the study understood the reasons for the death in all 209 adults. It used the proportional-hazards regression analysis to know the risks for an untimely death in adults with sickle cell anemia.

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Results: when the results for young kids and adults with sickle cell anemia were observed, it was found that the average age at death was 48 for women and 42 for men. Moreover, suffering from hemoglobin c disease had an average mortality age of 60 for men and 68 years for women.

 

In people with sickle cell disease, 18% of deaths took place in patients with mainly renal organ failures. 33% of the tested patients were medically free of organ failures but episodes of pain crisis took their life. Out of these patients, 78% experienced chronic pain, chest syndrome, or both, while 22% suffered a stroke that took their lives.

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Clinical modeling showed that people with sickle cell anemia faced acute chest syndrome, seizures, kidney failure, a white-cell count of over 15, 000 per cubic mm, and a low hemoglobin level were related to a risk of early death.

 

Conclusions: results suggested that 50% of patients with sickle cell anemia lived beyond the age of 50. A huge share of those who lost their lives suffered no noticeable chronic organ failure. However, most of them died due to acute episodes of pain or stroke. Early death was seen highest among patients who had symptomatic disease. High levels of fetal hemoglobin suggested improved chances of survival and are assumably a credible source to foresee the risks and other factors related to adult life expectancy.


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Life Expectancy And Risk Factors Involved In Sickle Cell Disease

Urinary tract infections (uti) can occur anywhere in the urinary system   the bladder, kidneys, urethra, and ureter. Most of these infections affect the lower part of the urinary system   urethra and the bladder.

An infection ;confined to the bladder can be frustrating and painful. You may experience pain during urination, and pus or blood in the urine. However, the condition becomes worse if the infection spreads to the upper part of the urinary system, particularly to the kidneys, triggering nausea, ;vomiting, and severe pain in the back.

If uti is left untreated, it can potentially lead to kidney damage   a condition known as pyelonephritis.

How does untreated uti affect the kidneys?

Untreated urinary tract infections can cause the kidneys to swell up and damage them permanently. The infections initially begin in the lower tract of your urinary system. Then the bacteria slowly enter your body through the urethra and begin multiplying and spreading up to the bladder. The bacteria eventually travel to your kidneys through the ureters.

Some people are at higher risk for kidney damage due to urinary tract infections. This includes  


	
	Pregnant women
	
	
	Elderly people
	
	
	People with kidney problems
	
	
	Someone with a weak immune system
	


Signs to watch out for

An untreated infection in the bladder that has spread to the kidneys is associated with symptoms, such as the following  


	
	Chills and ;fever
	
	
	Vomiting and nausea
	
	
	Pain in either side of your lower back
	


You should visit a doctor right away if you notice the above uti symptoms. The condition requires immediate medical intervention in order to prevent damage to your kidneys.

Symptoms of painful utis can be managed by combining medications and lifestyle remedies. Consult a specialist to diagnose the condition early and seek appropriate treatment to avoid complications.

Untreated Urinary Tract Infections And Kidney Damage: Know The Connection

World environment day is celebrated annually on 5th june. This day encourages awareness and action for the protection of our environment. It raises the problems facing our environment such as plastic pollution, air pollution, illegal wildlife trade, sea-level increase, sustainable consumption, and food security, among others. 

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World environment day is a reminder for us to pause and reflect on our actions and their subsequent consequences on the planet. 

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When was the world environment first celebrated?

The day was first observed in 1974 in the city of spokane in the usa.

 

History of world environment day (wed)

1972- the un general assembly established world environment day on the 1st day of the stockholm conference on the human environment. ;

1974- the first" world environment day" was held with the theme" only one earth. 

1987- the idea for rotating the center of these activities by selecting different host countries began. ;

 

Why is world environment day celebrated? ;

For a healthy life, the environment plays an important role. It provides us with air, food, etc. The environment is like our neighborhood, its surrounding conditions affect us and also modify development. It is really necessary to address the environmental issues like deforestation, increasing global warming, pollution, wastage and losses of food, etc. Currently, our earth is experiencing a triple planetary emergency: 


	
	Pollution is poisoning our air, land and water. ;
	
	
	Climate is heating up too quickly
	
	
	Habitat loss
	


The deteriorating environmental conditions worldwide had already raised alarms in academic circles, among scholars studying its conditions. However, general masses seemed oblivious to changes that were not directly affecting them.

The world environment day is structured in a manner that allows one country to take up the responsibility of selecting the theme and hosting the key celebrations each year. 

Let's all come together and ensure this unique and beautiful planet remains a comfortable home for humanity. 

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World Environment Day: What Is World Environment Day And Why It Is Celebrated? 

A brain tumour is a life-threatening situation. Most of the symptoms of the brain tumour are alike, but not all tumours are malignant. The most common type of brain tumour is meningioma. You may even don t need surgery in this case as they are really not dangerous or life-threatening.

 

Here are some of the facts you should know about meningioma:

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Meningioma can develop in numerous locations

 

Cells in the meninges, the lining of the brain and spinal cord, give rise to these tumours. In fact, they are not brain tumours at all, because they are not caused by the altered brain cells. ;

However, they continue to grow inside your sull, indicating that you should now take immediate steps. Meningioma can produce brain tumour symptoms if it grows or creates swelling that presses against the brain or other tissues in the skull.

 

Meningioma symptoms vary depending on the size and location of the tumour

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Meningioma can cause vision-related issues, headaches or seizures which are all common signs of a brain tumour. A headache, even a strong one, is seldom an indication of meningioma or any other type of brain tumour on its own. 

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Other tumour sites can influence your sense of smell, vision, hearing and even the pituitary gland s function.

 

Meningioma diagnosis usually happens when the doctor is looking for some else

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The discovery of a tumour on a ct scan or mri while investigating the patient for another cause, such as a head injury or another neurological condition, is called an accidental diagnosis. When a doctor identifies a meningioma, you will undergo additional testing to determine how the tumour will behave. A neurosurgeon will decide whether to remove the tumour or just monitor it to see whether it grows based on these findings. 

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Majority of meningioma does not spread

 

Being diagnosed with meningioma, especially a large one, might be shocking, but these tumours are usually non-dangerous. Tumour cells are unlikely to spread to other sections of the body as a result of this. ;

Meningiomas, on the other hand, can grow silently for years without creating any difficulties and they can grow to be enormous.

 

Things You Should Know About Most Common Brain Tumours

Surprising benefits of donating blood

Blood is that element in the human body that can't be manufactured. Hence, it makes blood donation a very significant phenomenon. It benefits the patients, the donors, society, and the overall medical ecosystem. However, people are not particularly aware of some of the benefits of donating blood. While some of them are necessarily good for your overall health, some can even surprise you.

Benefits

Potentially reveal health issues
Donating blood gets your vitals checked to make sure you are adequately fit for the procedure. Hence, it can be a process to keep your overall health checked. Your pulse, blood pressure, and hemoglobin check can ensure that you are free of any chronic illness. Usually, blood low in iron is not taken for donation. As a result, blood donation can find health issues that can be eradicated from the roots.

Reduce harmful overload of iron
Iron overload in the body causes a condition called hemochromatosis. Although this condition is not a usual phenomenon in india, it is important to detect it at the earliest. Blood donations help eliminate the excess iron from the body through red blood cells.

Cardio and vascular health
Regular blood donation maintains low blood pressure and keeps the risk of heart attacks at bay. According to a study, donating blood reduces the chance of heart attacks by 88 percent. High hemoglobin and high iron stores are checked by blood donations that have to do with blood clots and strokes.

Reduce the risk of cancer
A high concentration of iron in the body can cause free-radical damage. It increases the risk of cancer in the lungs, liver, colon, and throat due to the lowering of oxidative stress. Thus, regular blood donations make sure that the risk of cancer and mortality is lower.

Liver stays healthy
Excess iron in the body gets stored in the liver, heart, and pancreas leading to a risk of cirrhosis or liver failure. Various health ailments related to the liver are prevented by donating blood and getting rid of the extra iron in the body.

Help your mental state
With several physical benefits, there are also some psychological edges. As donating blood directly or indirectly helps a patient, it gives a sense of pride and satisfaction. Making a difference in society feels extremely fulfilling and that keeps you in an elated state. Hence, blood donation is equally healthy for your body and mind.

Surprising Benefits Of Donating Blood

Blood donation is a procedure carried out for the noble cause of helping patients and saving lives. As the healthy donor's blood is transfused into the patient, it gives them a new life. That said, the donor has to fulfill a few criteria to be eligible to donate blood.

Eligibility

While any healthy adult of any gender can donate blood, it is advised for males to donate once every three months and for females to donate once every four months. Some of the other criteria are-


	
	Age
	


Any person in the age group of 18 to 65 years can donate blood depending on other factors.


	
	Weight
	


A donor should be at least weigh 45 kilograms in order to be eligible.


	
	Pulse
	


The temperature and pulse of the donor should be normal during the time of blood donation.


	
	Hemoglobin
	


Hemoglobin in the blood should be at least 12.5 grams otherwise the donor stands ineligible.


	
	Childbirth
	


A female donor should have delivered at least 1 year ago and stopped lactation.


	
	Blood pressure
	


Ensuring that the systolic and diastolic pressures are within normal limits is a must.


	
	Malaria
	


One should not have malarial symptoms and not have been treated for the same in the last 3 months.


	
	Tattoo
	


A person should not have had a tattoo in the past 12 months.


	
	Immunization and vaccination
	


A donor should not have had shots for cholera, typhoid, diphtheria, tetanus, or plague in the last 15 days.


	
	Cancer
	


A person should be checked for cancer and should not have any signs of cancer in the body.


	
	Infection
	


There should not be hepatitis b, c, tuberculosis, leprosy, or hiv infection in the body.


	
	Diseases
	


A person should not have epilepsy, bleeding disorders, sickle cell, or thalassemia.


	
	Drugs
	


One cannot donate blood if injected intravenously ever. It may cause risk to the recipient.


	
	Heart issues
	


A person willing to donate cannot have any heart disease.


	
	Diabetes
	


People on oral drugs or dieting to control diabetes can donate blood while patients with insulin injections cannot.

 

Strictly prohibited


	
	Ones who have been tested hiv positive.
	
	
	People suffering from cardiac problems, hypertension, cancer, epilepsy, or kidney ailments.
	
	
	Donors who have consumed alcohol in the past 24 hours.
	
	
	Ones with a major dental procedure done in the last one month.
	
	
	Women with miscarriages in the past 6 months.
	



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Know Eligibility Rules For Donating Blood

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