Gastroesophageal reflux disease (GERD) is also called as acid reflux. It is a long-term digestive disorder that affects the lower esophageal sphincter, the ring of muscle between the esophagus and stomach which causes the stomach contents to come back up into the esophagus resulting in either symptoms or complications. Gastroesophageal reflux disease is mild acid reflux that occurs at least twice a week or moderate-to-severe acid reflux which occurs at least once a week.

Epidemiology

In western populations, GERD affects approximately 10% to 20% of the population and 0.4% newly develop the condition. In developed nations, the prevalence rate of GERD is associated with age; with adults aged 60 to 70 being the most commonly affected.

Signs and Symptoms

Esophageal symptoms include:

Heartburn
Regurgitation of food or sour liquid
Dysphagia
Sensation of a lump in the throat
Extraesophageal symptoms include:

Coughing and/or wheezing
Hoarseness, sore throat, or 
Otitis media
Noncardiac chest pain
Enamel erosion or other dental manifestations
New or worsening asthma
Disrupted sleep
Risk Factors

Obesity
Pregnancy
Hiatus hernia
Scleroderma and systemic sclerosis
The use of medicines such as prednisolone 
Delayed stomach emptying Zollinger-Ellison syndrome which can show an increase in gastric acidity because of gastrin production
A high blood calcium level which can increase gastrin production, leading to increased acidity
Visceroptosis or Gl nard syndrome, in which the stomach has sunk in the abdomen upsetting the motility and acid secretion of the stomach.
Factors that can increase acid reflux involve:

Smoking habit
Eating heavy meals or eating late at night
Eating fatty or fried foods
Drinking certain beverages, such as alcohol or coffee
Medications, such as aspirin
Tight clothes
Increased intra-abdominal pressure
Differential Diagnosis

Heart disease causing chest pain
Laryngopharyngeal reflux OR extraesophageal reflux disease
Infection
Peptic ulcer
Esophageal spasm
Complications

Narrowing of the esophagus (esophageal stricture): Stomach acid causes the formation of a scar tissue which narrows the food pathway.
An open sore in the esophagus (esophageal ulcer): Acid causes an open sore which bleeds, causes pain, and makes swallowing difficult.
Precancerous changes in the esophagus (Barrett's esophagus): Damage from acid can cause changes in the tissue lining the lower esophagus
Anemia
How to arrive at the diagnosis?

Upper gastrointestinal endoscopy/esophagogastroduodenoscopy
Esophageal manometry
Ambulatory 24-hour pH monitoring
Treatment

The goals of treatment are controlling symptoms, healing esophagitis, and prevention of recurrent esophagitis or other complications. Lifestyle modifications include the following:

Losing weight (if overweight)
Eating small and frequent meals instead of large meals
Waiting 3 hours after a meal to lie down
Elevating the head end of the bed by 8 inches
Avoiding bending or stooping positions
Medications

H2 receptor antagonists (ranitidine, cimetidine)
Proton pump inhibitors (omeprazole, pantoprazole)
Prokinetic agents (aluminum hydroxide)
Antacids (magnesium hydroxide)
Surgery

Transthoracic and transabdominal fundoplication
Placement of a device to augment the lower esophageal sphincter

Gastroesophageal Reflux Disease - What Causes It?

From time to time each person tends to get dyspepsia which is basically a mild discomfort in the upper belly or abdomen. Dyspepsia which is also known as indigestion affects millions of people on a daily basis. It s mostly caused by over eating, eating greedily or worse conditions such as stomach ulcer, irritable bowel syndrome or gastrointestinal disease. 

Medically dyspepsia is defined as difficult digestion that is sometimes accompanied with symptoms such as vomiting, heartburn, nausea and bloating. A treatment plan for the patient is usually determined by what causes the indigestion. Below are some of the treatment options available to patients.
Antacids, h-2-receptor antagonists and ppls (proton pump inhibitors)

These three type of drugs all work to reduce the levels of acid in the stomach. Doctors tend to prescribe antacids as the first drug which are usually over the counter and require no prescription. In spite of antacids working fast, h-2-receptor antagonists tend to last longer. However, h-2-receptor antagonists tend to have side effects such as nausea and diarrhea. The other drug option is ppls which is very effective for patients with dyspepsia and also suffer from gastroesophageal reflux disease. 

They are stronger than h-2-receptor antagonists.

Prokinetics and antibiotics: This medication is usually prescribed to treat indigestion and works if the stomach empties slowly. Antibiotics on the other hand are used when indigestion is a result of peptic ulcers caused by Helicobacter pylori.
Antidepressants: There are a lot of factorsthat cause dyspepsia. However, if the doctors cannot find any cause of a patient s indigestion and no other drug has been effective, they tend to prescribe antidepressants. This medication is used to lessen the level of discomfort that comes with dyspepsia thereby reducing pain.
Home remedies: There are a few studies on natural remedies that can help treat dyspepsia. One of the remedies is to use baking soda to neutralize the stomach acid. This remedy is said to be more effective than antacids. Then there is ginger which while not mentioned to be effective in treating indigestion, helps in relieving nausea and has no side effects. Also peppermint has an effect on how the gastrointestinal tract works and helps with irritable bowel syndrome. However, it does not have a large effect on dyspepsia.
Diet and lifestyle changes: Indigestion is mostly caused by what we put into our bodies or eat and one way of treating it is by controlling our diet. This will especially work if you have mild symptoms that do not occur often. It s advisable to consume foods that are low or reduced in fat content and to, avoid or limit alcohol, chocolates and caffeine. You should also get enough sleep.
A healthy lifestyle goes a long way in helping to relieve indigestion.

Dyspepsia - 4 Best Ways It Can Be Treated!

Colon cancer is believed to be one of the common types of cancer affecting people. As the name suggests, here, the point of origin of the cancer is the colon or the large intestine. Though colon cancer can affect anyone, people with unhealthy lifestyle (sedentary) and habits (excess smoking and consumption of alcohol), obesity, certain medical conditions like diabetes, or exposed to radiations (radiation therapy) are at a greater risk of colon cancer. Colon cancer may also be hereditary.

Colon cancer usually proceeds through five stages, stage 0 (zero), stage I, II, III and IV.

In stage 0, cancer remains in situ, (it remains confined within the innermost layer of the colon).
In stage I, cancer slowly starts spreading to the other layers (second and third) of the inner walls of the colon.
In stage II, cancer spreads further to the muscular walls of the colon (the lymph nodes, are, however, still not affected by this condition).
In stage III, cancer spreads outside the colon, affecting one or more lymph nodes.
Stage IV is more severe and metastatic. Here cancer has spread to and affected vital organs like the liver and the lungs.
Many of the symptoms do not appear at the initial stages. As a result, colon cancer mostly gets detected at a later (often metastatic) stage. Thus, a person should be alert. The initial symptoms, no matter how trivial, should be taken seriously. There is no harm in seeking medical help. It will only help you in the long run. 

The following symptoms are often the initial or first signs of something as big as colon cancer.

Unexplained poor appetite followed by sudden and rapid weight loss. Losing weight at an alarming rate without sweating it out needs thorough investigation. More than often, colon cancer interferes with the digestion process in a person. A person is not able to eat well. There is a feeling of being full (irrespective of how much you eat) all the time.
Constipation, gas or (and) diarrhea. Often overlooked and mistaken for common bowel disorder, these are some of the initial symptoms of colon cancer. The symptoms may be an outcome of polyps (abnormal tissue growths that can take place in any organs. These polyps are mostly benign in nature) or malignant tumors in the colon. Seek medical help if the conditions persist for more than a week. It is better to be safe than to be sorry.
A person feels exhausted, sleepy and weak all the time. The symptom may be an outcome of iron deficiency and anemia. Colon cancer can cause injury to the digestive tract. There may be bleeding followed by blood loss and hence the associated symptoms.
Mild to severe abdominal pain. The abdomen also appears tender than usual (in the case of metastatic tumor).
Stomach upset accompanied by pain, nausea, vomiting, cramps and at times, indigestion (an outcome of intestinal obstruction and inflammation).
There may be blood while passing stool.

Colon Cancer - What Signs You Must Watch Out For?

How does salt help in clearing skin?

Of all the health problems current lifestyle poses, one that harasses both men are women, at times even in their 30s, is marks or blemishes on the face. Acne and blemishes have become almost constant features on the skin, all thanks to the irregular eating habits, junk food, alcohol, late nights and of course, pollution. It is one of the lesser known facts that salt helps clear up the skin. Sea salt and epsom salt are the ideal salts to be used. Let us see how.

1. Salt for bathing - adding salt to your bath is advised for physical and spiritual cleansing. After you are done with your usual bath and washed off the soap, have a bath with salt mixed water. This not only clears the complexion overall but also lightens dark marks on the body.
2. Salt for application - two teaspoons of sea salt mixed with water and applied on the face with cotton, three times a day is said to treat the problem of acne. Having the natural ability to reduce moisture, salt does wonders to your skin by drying out the oils. This eliminates chances of pores getting clogged, closes them and increasing bacterial buildup.
3. Salt as a mask - salt when mixed with honey makes a great mask for the skin. Since both the ingredients have anti-inflammatory properties, this mask soothes the skin, retains hydration in the skin and balances the oil production. A couple of teaspoons of finely ground sugar, when mixed with double the amount of raw honey, makes a perfect balancing mask for the skin.
4. Salt as toner spray - a teaspoon of sea salt mixed with some warm water in a spray bottle until the salt is dissolved makes for a perfect spray toner. Make sure to avoid the eyes, though.
5. Salt for exfoliation - salt is known to be a skin-exfoliate and is often found in body scrubs. One can also make scrubs at home by mixing together aloe vera juice or gel, salt, oil of your choice, essential oil and dried lavender flowers.

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Do You Know Salt Is Only God For Clear Skin?

Obesity can make life miserable. From unhealthy eating habits to unhealthy lifestyles and medical conditions, obesity can be an amalgamation of many factors. Obese people are a greater risk of suffering from many serious health complications like type-2 diabetes, mood swings, and depression, cardiac problems, high blood pressure and high cholesterol, to name a few. It does not stop there. More alarming is the fact that obese people are an increased risk of suffering from different types of cancer.

Bariatric surgery comes as a saviour for highly obese people (with a BMI over 40), who have tried every possible treatment under the sun to lose weight without any success. Bariatric surgery has helped many severely obese people attain a healthy weight. Bariatric surgery can be of three types;

Gastric bypass surgery (Roux-en-Y): This is one of the most common types of weight-loss surgery practised worldwide. The procedure involves rearranging (dividing) the stomach into a smaller upper pouch and a larger lower part. The smaller pouch is then connected to the small intestine. The food consumed will pass into the small intestine through the pouch. The idea is to rearrange the stomach in such a way that a person consumes a lesser quantity of food.
Gastric banding (Laparoscopic Adjustable Gastric Band): In this procedure, the surgeon creates a small pouch at the upper part of the stomach by placing a band (lap band or A-band) around it. The pouch, true to its name, is used to hold the food consumed. The purpose of placing a band around the stomach (upper part) is to reduce the intake of food.
Sleeve Gastrectomy (Gastric Sleeve surgery): In Sleeve Gastrectomy, surgeons remove a large portion of the stomach, leaving behind only a small sleeve-like pouch (hence the name). Like the other two surgeries, sleeve gastrectomy also aids in limiting the consumption of food.
Duodenal switch: The fourth type of bariatric surgery, Duodenal switch with biliopancreatic diversion, is not very commonly used. Bariatric surgery has several health benefits. In addition to the weight loss, it plays a pivotal role in lowering the incidences of Type-2 Diabetes, depression, anxiety, coronary artery problems, sleep apnea cardiovascular diseases.
Research also suggest that bariatric surgery has been instrumental in reducing the chances of cancer (especially colon and breast cancer) by as much as 60%. The correlation between weight loss and reduced cancer instances is still a debatable topic. Some researchers and oncologists believe that the weight loss (bariatric surgery) brings about a hormonal modification which prevents the growth of tumour cells. Another study links obesity with an increased inflammation. In many cases, inflammation acts as a catalyst, accelerating the growth of cancer cells. Research is still going on to understand this correlation (obesity and reduced cancer rates) better.

Bariatric surgery has its share of risks and demerits. Consult your physician and get yourself thoroughly examined before opting for the surgery.

Does Bariatric Surgery Reduces The Risk Of Cancer?

Any kind of injury on the surface of the skin is immediately noticed by us, but when something happens to one of our internal organs, it can take a little longer to get to your notice for example, an obstruction in the bile duct. The bile duct is a tubular structure responsible for carrying bile from the liver and gall bladder through the pancreas to the small intestine. This bile helps the digestion process and the absorption of fat.

An obstruction in the bile duct can be triggered by a number of factors. Some of these are:

    Gallstones
    Inflammation of the bile ducts
    Cysts
    Traumatic accidents
    Bile duct or pancreatic tumors
    Hepatitis infections
    Cirrhosis or severe liver damage
    Abnormal narrowing of the bile duct

This can affect anyone, but the people who have a history of gall stones or tumors in the abdomen are at a higher risk of suffering from bile duct obstruction. Chronic pancreatitis, sudden weight loss or obesity can also increase this risk. The symptoms of biliary obstruction include light coloured stool, dark urine, pain in the upper right abdomen, nausea, vomiting and fever. Your doctor will also probably need an X-ray of the bile ducts, blood tests, a hepatobiliary iminodiacetic acid scan and ultrasonograph to confirm a diagnosis before they can start treating you for the same.

If not treated in time, bile duct blockages can lead to a dangerous buildup of bilirubin in the body and trigger a number of life threatening diseases. Treatment for biliary obstruction can be through medication or surgery with surgery being the more preferred mode of treatment. It is aimed at resolving the underlying cause of the obstruction and alleviating the blockage. Treatment for biliary obstruction can be two common forms of treatment include a cholecystectomy and ERCP. The former involves the removal of the gall bladder and is suited to obstructions caused by gallstones. The latter is a procedure to remove small stones from the bile duct or place a stent inside the duct.

There are many ways bile duct obstruction can be prevented which first and foremost includes following a healthy lifestyle. If you are overweight, exercise for at least half an hour a day to regulate your weight and reach a healthy BMI. Decrease your intake of sugar and saturated fats as both these can cause gall stones. Also, increase the amount of fibre in your diet. All the above mentioned tips will certainly help you in preventing bile duct obstruction.

Bile Duct Blockage -  8 Factors Behind it!

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